Crystal structure of a Trypanosoma brucei metacaspase

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Crystal structure of a Trypanosoma brucei metacaspase is …
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scholarly articleQ13442814

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P819ADS bibcode2012PNAS..109.7469M
P356DOI10.1073/PNAS.1200885109
P932PMC publication ID3358904
P698PubMed publication ID22529389
P5875ResearchGate publication ID224824955

P50authorJana RudolfQ81416163
Jeremy C. MottramQ41417991
P2093author name stringKaren McLuskey
Neil W Isaacs
Graham H Coombs
Catherine X Moss
William R Proto
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Two Arabidopsis metacaspases AtMCP1b and AtMCP2b are arginine/lysine-specific cysteine proteases and activate apoptosis-like cell death in yeastQ45251284
Metacaspase 2 of Trypanosoma brucei is a calcium-dependent cysteine peptidase active without processingQ46898424
Bloodstream form Trypanosoma brucei depend upon multiple metacaspases associated with RAB11-positive endosomesQ46968629
Metacaspase-dependent programmed cell death is essential for plant embryogenesisQ47668098
Metacaspase activity of Arabidopsis thaliana is regulated by S-nitrosylation of a critical cysteine residueQ49069048
Arabidopsis Type I Metacaspases Control Cell DeathQ57051912
Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphomaQ24290550
Cysteine protease mcII-Pa executes programmed cell death during plant embryogenesisQ24530417
Knockout of caspase-like gene, YCA1, abrogates apoptosis and elevates oxidized proteins in Saccharomyces cerevisiaeQ24538781
Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegmentQ24561952
MEROPS: the peptidase databaseQ24644757
Crystal structure of gingipain R: an Arg-specific bacterial cysteine proteinase with a caspase-like foldQ27619994
The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivityQ27625099
Small Molecule-Induced Allosteric Activation of the Vibrio cholerae RTX Cysteine Protease DomainQ27652468
Mechanistic and structural insights into the proteolytic activation of Vibrio cholerae MARTX toxinQ27655603
Substrate-Induced Conformational Changes Occur in All Cleaved Forms of Caspase-6Q27666081
Crystal structure of the mucosa-associated lymphoid tissue lymphoma translocation 1 (MALT1) paracaspase regionQ27676124
Crystal structure of the wild-type human procathepsin B at 2.5 A resolution reveals the native active site of a papain-like cysteine protease zymogenQ27743415
Metacaspase Yca1 is required for clearance of insoluble protein aggregates.Q27934472
Mechanisms of caspase activationQ28187994
Type II metacaspases Atmc4 and Atmc9 of Arabidopsis thaliana cleave substrates after arginine and lysineQ28278397
Classification of the caspase-hemoglobinase fold: detection of new families and implications for the origin of the eukaryotic separinsQ30809775
A non-death role of the yeast metacaspase: Yca1p alters cell cycle dynamics.Q33359593
Calcium-dependent activation and autolysis of Arabidopsis metacaspase 2d.Q33786493
The meaning of death: evolution and ecology of apoptosis in protozoan parasitesQ34102675
Caspase activation: revisiting the induced proximity modelQ34328287
Clan CD cysteine peptidases of parasitic protozoaQ35104744
Metacaspases.Q35210619
Trypanosoma brucei metacaspase 4 is a pseudopeptidase and a virulence factorQ35562663
The protein structures that shape caspase activity, specificity, activation and inhibitionQ35902423
Programmed cell death in plant embryogenesisQ36159265
Are metacaspases caspases?Q39752566
Design and evaluation of Trypanosoma brucei metacaspase inhibitors.Q39807680
Lanthanides as probes for calcium in biological systemsQ39810508
An essential role for the Leishmania major metacaspase in cell cycle progression.Q40074936
P433issue19
P407language of work or nameEnglishQ1860
P921main subjectTrypanosoma bruceiQ33244
crystal structureQ895901
P304page(s)7469-7474
P577publication date2012-04-23
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleCrystal structure of a Trypanosoma brucei metacaspase
P478volume109

Reverse relations

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