Trypanosoma brucei metacaspase 4 is a pseudopeptidase and a virulence factor

scientific article published on 23 September 2011

Trypanosoma brucei metacaspase 4 is a pseudopeptidase and a virulence factor is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M111.292334
P932PMC publication ID3220528
P698PubMed publication ID21949125

P50authorJeremy C. MottramQ41417991
Alana HamiltonQ63651583
Laurence TetleyQ80154182
P2093author name stringGraham H Coombs
Luiz Juliano
Catherine X Moss
William R Proto
Esther Castanys-Munoz
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The GPI-phospholipase C of Trypanosoma brucei is nonessential but influences parasitemia in mice.Q41980701
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Two Arabidopsis metacaspases AtMCP1b and AtMCP2b are arginine/lysine-specific cysteine proteases and activate apoptosis-like cell death in yeastQ45251284
Metacaspase 2 of Trypanosoma brucei is a calcium-dependent cysteine peptidase active without processingQ46898424
Bloodstream form Trypanosoma brucei depend upon multiple metacaspases associated with RAB11-positive endosomesQ46968629
Flagellar motility is required for the viability of the bloodstream trypanosomeQ47219440
Inactive enzyme-homologues find new function in regulatory processesQ47311616
Metacaspase activity of Arabidopsis thaliana is regulated by S-nitrosylation of a critical cysteine residueQ49069048
Expression and cellular localisation of calpain-like proteins in Trypanosoma brucei.Q52699031
Use of monoclonal antibodies to analyse the expression of a multi-tubulin family.Q54195556
Arabidopsis Type I Metacaspases Control Cell DeathQ57051912
Protein transport and flagellum assembly dynamics revealed by analysis of the paralysed trypanosome mutant snl-1Q61540312
Double-stranded RNA interference in Trypanosoma brucei using head-to-head promotersQ73214229
Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphomaQ24290550
Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signalingQ24298141
Cysteine protease mcII-Pa executes programmed cell death during plant embryogenesisQ24530417
Mechanism of procaspase-8 activation by c-FLIPLQ27655368
A metacaspase of Trypanosoma brucei causes loss of respiration competence and clonal death in the yeast Saccharomyces cerevisiaeQ27932448
Metacaspase Yca1 is required for clearance of insoluble protein aggregates.Q27934472
A caspase-related protease regulates apoptosis in yeastQ27938405
Type II metacaspases Atmc4 and Atmc9 of Arabidopsis thaliana cleave substrates after arginine and lysineQ28278397
A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma bruceiQ29617358
Intraflagellar transport and functional analysis of genes required for flagellum formation in trypanosomesQ30481394
A non-death role of the yeast metacaspase: Yca1p alters cell cycle dynamics.Q33359593
Exocytosis and protein secretion in Trypanosoma.Q33526674
High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosomeQ33833378
Calflagin inhibition prolongs host survival and suppresses parasitemia in Trypanosoma brucei infectionQ33983124
Trypanosome-derived oligopeptidase B is released into the plasma of infected rodents, where it persists and retains full catalytic activityQ34007095
Human caspases: activation, specificity, and regulationQ34608215
Global analysis of protein palmitoylation in African trypanosomes.Q34739483
Oligopeptidase B deficient mutants of Leishmania majorQ35089762
Clan CD cysteine peptidases of parasitic protozoaQ35104744
Metacaspases.Q35210619
Kinetoplastid PPEF phosphatases: dual acylated proteins expressed in the endomembrane system of LeishmaniaQ35830228
New approaches to the microscopic imaging of Trypanosoma brucei.Q35938657
A cytosolic serine endopeptidase from Trypanosoma cruzi is required for the generation of Ca2+ signaling in mammalian cellsQ36258539
Exosomes and other microvesicles in infection biology: organelles with unanticipated phenotypesQ37805756
P433issue46
P407language of work or nameEnglishQ1860
P921main subjectTrypanosoma bruceiQ33244
Metacaspase-4Q61561024
P304page(s)39914-39925
P577publication date2011-09-23
P1433published inJournal of Biological ChemistryQ867727
P1476titleTrypanosoma brucei metacaspase 4 is a pseudopeptidase and a virulence factor
P478volume286

Reverse relations

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