Insights into Soluble Guanylyl Cyclase Activation Derived from Improved Heme-Mimetics

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Insights into Soluble Guanylyl Cyclase Activation Derived from Improved Heme-Mimetics is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1021/JM400539D
P932PMC publication ID3902542
P698PubMed publication ID24090476
P5875ResearchGate publication ID257348526

P50authorAndreas PapapetropoulosQ40644576
Antonia MaraziotiQ59681629
Vijay KumarQ80829363
P2093author name stringFocco van den Akker
Georgios A Spyroulias
Zongmin Zhou
Athanassios Giannis
Margarete von Wantoch Rekowski
Johann Moschner
Marina Bantzi
P2860cites workNO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potentialQ24656131
Structure of cinaciguat (BAY 58-2667) bound to Nostoc H-NOX domain reveals insights into heme-mimetic activation of the soluble guanylyl cyclaseQ27661554
Insights into BAY 60-2770 Activation and S -Nitrosylation-Dependent Desensitization of Soluble Guanylyl Cyclase via Crystal Structures of Homologous Nostoc H-NOX Domain ComplexesQ27677544
Guanylyl cyclases and signaling by cyclic GMP.Q33917038
NO-independent, haem-dependent soluble guanylate cyclase stimulatorsQ34906036
Soluble guanylate cyclase as an emerging therapeutic target in cardiopulmonary diseaseQ35010064
Regulation of nitric oxide-sensitive guanylyl cyclaseQ35185117
Diazonamide support studies: stereoselective formation of the C10 chiral center in both the CDEFG and AEFG fragmentsQ37089141
NO- and haem-independent soluble guanylate cyclase activatorsQ37352787
Role of guanylate cyclase modulators in decompensated heart failureQ37537154
Nitrate therapy: new aspects concerning molecular action and toleranceQ37876052
Expression and characterization of the catalytic domains of soluble guanylate cyclase: interaction with the heme domainQ39369792
The nitrovasodilators. New ideas about old drugsQ40905911
Soluble guanylate cyclase: the forgotten sibling.Q41698395
Synthesis of N-benzyl- and N-phenyl-2-amino-4,5-dihydrothiazoles and thioureas and evaluation as modulators of the isoforms of nitric oxide synthase.Q44570520
Identification of residues crucially involved in the binding of the heme moiety of soluble guanylate cyclaseQ44626758
4-(Phenylsulfonamidomethyl)benzamides as potent and selective inhibitors of the 11beta-hydroxysteroid dehydrogenase type 1 with efficacy in diabetic ob/ob mice.Q45947580
Synthesis, characterization and structure-activity relationship analysis of novel depsides as potential antibacterialsQ46551626
Electrochemically assisted Heck reactions.Q51321151
P433issue21
P407language of work or nameEnglishQ1860
P921main subjectdrug discoveryQ1418791
P304page(s)8948-8952
P577publication date2013-10-24
P1433published inJournal of Medicinal ChemistryQ900316
P1476titleInsights into soluble guanylyl cyclase activation derived from improved heme-mimetics
P478volume56

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cites work (P2860)
Q28084239Agents with vasodilator properties in acute heart failure: how to design successful trials
Q39320532Bacterial Haemoprotein Sensors of NO: H-NOX and NosP.
Q42361109Regulation of soluble guanylyl cyclase redox state by hydrogen sulfide

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