Structure of the Toxoplasma gondii ROP18 Kinase Domain Reveals a Second Ligand Binding Pocket Required for Acute Virulence

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Structure of the Toxoplasma gondii ROP18 Kinase Domain Reveals a Second Ligand Binding Pocket Required for Acute Virulence is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M113.523266
P3181OpenCitations bibliographic resource ID1752552
P932PMC publication ID3843107
P698PubMed publication ID24129568

P50authorJeroen P SaeijQ67222671
Emily E RosowskiQ83104125
P2093author name stringMichael B Yaffe
Daniel Lim
Daniel A Gold
Wendy Niedelman
Lindsay Julien
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A secreted serine-threonine kinase determines virulence in the eukaryotic pathogen Toxoplasma gondiiQ34591236
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ATF6beta is a host cellular target of the Toxoplasma gondii virulence factor ROP18.Q35102296
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The effect of polylysine on casein-kinase-2 activity is influenced by both the structure of the protein/peptide substrates and the subunit composition of the enzymeQ68110979
P4510describes a project that usesImageQuantQ112270642
P433issue48
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
Toxoplasma gondiiQ131003
virulenceQ1460232
ligand bindingQ61659151
binding pocketQ61659196
P304page(s)34968-34980
P577publication date2013-10-15
P1433published inJournal of Biological ChemistryQ867727
P1476titleStructure of the Toxoplasma gondii ROP18 kinase domain reveals a second ligand binding pocket required for acute virulence
P478volume288