scholarly article | Q13442814 |
P50 | author | Omar S. Harb | Q55153327 |
Lucia Peixoto | Q55979536 | ||
David S Roos | Q56394669 | ||
P2093 | author name string | Feng Chen | |
Daniel P Beiting | |||
Paul H Davis | |||
Catie Small Brownback | |||
Dinkorma Ouloguem | |||
P2860 | cites work | The dictyostelium kinome--analysis of the protein kinases from a simple model organism. | Q21145270 |
MUSCLE: a multiple sequence alignment method with reduced time and space complexity | Q21284290 | ||
The protein kinase complement of the human genome | Q24324497 | ||
The rice kinase database. A phylogenomic database for the rice kinome | Q24670049 | ||
Protein kinases of the human malaria parasite Plasmodium falciparum: the kinome of a divergent eukaryote | Q24792290 | ||
PHYML Online--a web server for fast maximum likelihood-based phylogenetic inference | Q24811999 | ||
Comparative analysis of the kinomes of three pathogenic trypanosomatids: Leishmania major, Trypanosoma brucei and Trypanosoma cruzi | Q24815881 | ||
DAVID: Database for Annotation, Visualization, and Integrated Discovery | Q27499374 | ||
Novel structural and regulatory features of rhoptry secretory kinases in Toxoplasma gondii | Q27653674 | ||
Profile hidden Markov models | Q27860536 | ||
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources | Q27860739 | ||
A Simple, Fast, and Accurate Algorithm to Estimate Large Phylogenies by Maximum Likelihood | Q27861000 | ||
PAML: a program package for phylogenetic analysis by maximum likelihood | Q27861096 | ||
The protein kinases of budding yeast: six score and more | Q27930077 | ||
A novel protein kinase family in Plasmodium falciparum is differentially transcribed and secreted to various cellular compartments of the host cell | Q27972747 | ||
Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification | Q28131753 | ||
Evolution of protein kinase signaling from yeast to man | Q28205635 | ||
Genetics. Themes and variations in apicomplexan parasite biology | Q28259689 | ||
The toxoplasma kinase ROP18: an active member of a degenerate family | Q28763605 | ||
Dynamics of Toxoplasma gondii differentiation | Q30806899 | ||
The ROP2 family of Toxoplasma gondii rhoptry proteins: proteomic and genomic characterization and molecular modeling | Q33259406 | ||
ROP18 is a rhoptry kinase controlling the intracellular proliferation of Toxoplasma gondii | Q33274196 | ||
Reranking candidate gene models with cross-species comparison for improved gene prediction | Q33375875 | ||
Selection at a single locus leads to widespread expansion of Toxoplasma gondii lineages that are virulent in mice | Q33415462 | ||
Toxoplasma gondii bradyzoites form spontaneously during sporozoite-initiated development | Q33765729 | ||
The protein kinases of Caenorhabditis elegans: a model for signal transduction in multicellular organisms | Q33777991 | ||
Stage differentiation of the protozoan parasite Toxoplasma gondii | Q33815044 | ||
Toxoplasma gondii: transmission, diagnosis and prevention | Q34155408 | ||
Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii | Q34432069 | ||
The apicoplast: A plastid in Plasmodium falciparum and other apicomplexan parasites | Q34533262 | ||
Emerging roles of pseudokinases | Q34552850 | ||
Rethinking pseudokinases | Q34590810 | ||
A secreted serine-threonine kinase determines virulence in the eukaryotic pathogen Toxoplasma gondii | Q34591236 | ||
Determination of the genera of cyst-forming coccidia | Q35541176 | ||
Differences among the three major strains of Toxoplasma gondii and their specific interactions with the infected host | Q36228600 | ||
ToxoDB: an integrated Toxoplasma gondii database resource | Q36454249 | ||
Rhoptries: an arsenal of secreted virulence factors | Q36998670 | ||
Kiss and spit: the dual roles of Toxoplasma rhoptries | Q37024471 | ||
Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue | Q37087502 | ||
Polymorphic secreted kinases are key virulence factors in toxoplasmosis | Q37105671 | ||
Infection with Toxoplasma gondii results in dysregulation of the host cell cycle | Q37109789 | ||
The Toxoplasma gondii rhoptry protein ROP4 is secreted into the parasitophorous vacuole and becomes phosphorylated in infected cells. | Q37579631 | ||
A helical membrane-binding domain targets the Toxoplasma ROP2 family to the parasitophorous vacuole | Q39812575 | ||
Toxoplasma gondii rhoptry discharge correlates with activation of the early growth response 2 host cell transcription factor | Q39954131 | ||
Toxoplasma gondii sequesters lysosomes from mammalian hosts in the vacuolar space | Q40289140 | ||
The host cell transcription factor hypoxia-inducible factor 1 is required for Toxoplasma gondii growth and survival at physiological oxygen levels | Q40324186 | ||
Molecular tools for genetic dissection of the protozoan parasite Toxoplasma gondii | Q40501292 | ||
Microarray analysis reveals previously unknown changes in Toxoplasma gondii-infected human cells | Q43569597 | ||
Origins, lineage-specific expansions, and multiple losses of tyrosine kinases in eukaryotes | Q44159571 | ||
Evolution from fish to mammals by gene duplication | Q45239092 | ||
Organellar dynamics during the cell cycle of Toxoplasma gondii. | Q46645614 | ||
Toxoplasma gondii interferes with lipopolysaccharide-induced mitogen-activated protein kinase activation by mechanisms distinct from endotoxin tolerance. | Q51024816 | ||
Pseudokinases: functional insights gleaned from structure. | Q54774270 | ||
A genomic perspective of protein kinases in Plasmodium falciparum | Q56558814 | ||
Sequential protein secretion from three distinct organelles of Toxoplasma gondii accompanies invasion of human fibroblasts | Q73478363 | ||
Inverted topology of the Toxoplasma gondii ROP5 rhoptry protein provides new insights into the association of the ROP2 protein family with the parasitophorous vacuole membrane | Q80032319 | ||
P4510 | describes a project that uses | limma | Q112236343 |
P433 | issue | 2 | |
P304 | page(s) | 208-218 | |
P577 | publication date | 2010-08-01 | |
P1433 | published in | Cell Host & Microbe | Q5058153 |
P1476 | title | Integrative genomic approaches highlight a family of parasite-specific kinases that regulate host responses | |
P478 | volume | 8 |
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