Serum response factor regulates immediate early host gene expression in Toxoplasma gondii-infected host cells

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Serum response factor regulates immediate early host gene expression in Toxoplasma gondii-infected host cells is …
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scholarly articleQ13442814

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P819ADS bibcode2011PLoSO...618335W
P356DOI10.1371/JOURNAL.PONE.0018335
P932PMC publication ID3066233
P698PubMed publication ID21479245
P5875ResearchGate publication ID51038175

P2093author name stringIra J Blader
Crystal Teygong
Eric Phelps
Jay Radke
Mandi Wiley
P2860cites workChanges in the expression of human cell division autoantigen-1 influence Toxoplasma gondii growth and developmentQ21131617
Inhibition of caspase activation and a requirement for NF-kappaB function in the Toxoplasma gondii-mediated blockade of host apoptosisQ42796145
Anthrax lethal factor-cleavage products of MAPK (mitogen-activated protein kinase) kinases exhibit reduced binding to their cognate MAPKsQ43003536
Microarray analysis reveals previously unknown changes in Toxoplasma gondii-infected human cellsQ43569597
Inhibition of host cell apoptosis by Toxoplasma gondii is accompanied by reduced activation of the caspase cascade and alterations of poly(ADP-ribose) polymerase expressionQ43781488
Rho protein-mediated changes in the structure of the actin cytoskeleton regulate human inducible NO synthase gene expressionQ44473522
A novel role for serum response factor in neuronal survival.Q44785518
Complexities in ETS-domain transcription factor function and regulation: lessons from the TCF (ternary complex factor) subfamily. The Colworth Medal LectureQ48362966
Host cell Ca2+ and protein kinase C regulate innate recognition of Toxoplasma gondii.Q64985972
AP-1 complexes containing cJun and JunB cause cellular transformation of Rat1a fibroblasts and share transcriptional targetsQ73876722
Parasitehost cell interactions in toxoplasmosis: new avenues for intervention?Q76384892
p38 MAPK autophosphorylation drives macrophage IL-12 production during intracellular infectionQ81546534
Signal-regulated activation of serum response factor is mediated by changes in actin dynamicsQ22010445
4-Bromophenacyl bromide specifically inhibits rhoptry secretion during Toxoplasma invasionQ28472120
ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivationQ28578241
Actin dynamics control SRF activity by regulation of its coactivator MALQ28646140
ToxoplasmosisQ30080013
Host cell invasion by Toxoplasma gondii is temporally regulated by the host microtubule cytoskeletonQ30497318
A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3.Q33591077
Communication between Toxoplasma gondii and its host: impact on parasite growth, development, immune evasion, and virulenceQ33606893
Lytic cycle of Toxoplasma gondiiQ34023676
Toxoplasma gondii activates hypoxia-inducible factor (HIF) by stabilizing the HIF-1alpha subunit via type I activin-like receptor kinase receptor signalingQ34094330
Linking actin dynamics and gene transcription to drive cellular motile functionsQ34111717
Toxoplasma rhoptry protein 16 (ROP16) subverts host function by direct tyrosine phosphorylation of STAT6.Q34121309
Integrative genomic approaches highlight a family of parasite-specific kinases that regulate host responsesQ34238191
Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression.Q34304925
Glucosylation of Rho proteins by Clostridium difficile toxin B.Q34312765
Strain-specific activation of the NF-kappaB pathway by GRA15, a novel Toxoplasma gondii dense granule protein.Q34501481
Toxoplasma gondii: the model apicomplexan.Q34909928
SRF-dependent gene expression is required for PI3-kinase-regulated cell proliferationQ35123848
Ets ternary complex transcription factorsQ35615313
Toxoplasma gondii targets a protein phosphatase 2C to the nuclei of infected host cells.Q35641036
Toxin-induced resistance in Bacillus anthracis lethal toxin-treated macrophages.Q36350534
Two pathways for serum regulation of the c-fos serum response element require specific sequence elements and a minimal domain of serum response factorQ36665209
Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologueQ37087502
Toxoplasma gondii actively remodels the microtubule network in host cellsQ37394996
Phenotypic and gene expression changes among clonal type I strains of Toxoplasma gondiiQ37477708
Membrane translocation by anthrax toxinQ37535082
Transcriptional profile of Toxoplasma gondii-infected human fibroblasts as revealed by gene-array hybridizationQ37873587
Association of host cell endoplasmic reticulum and mitochondria with the Toxoplasma gondii parasitophorous vacuole membrane: a high affinity interactionQ38342669
Cytosolic delivery and characterization of the TcdB glucosylating domain by using a heterologous protein fusionQ39518070
Toxoplasma evacuoles: a two-step process of secretion and fusion forms the parasitophorous vacuoleQ39735086
Toxoplasma gondii rhoptry discharge correlates with activation of the early growth response 2 host cell transcription factorQ39954131
Epithelial cell-cell contacts regulate SRF-mediated transcription via Rac-actin-MAL signallingQ40003513
Toxoplasma gondii sequesters lysosomes from mammalian hosts in the vacuolar spaceQ40289140
Early growth response protein 1 (Egr-1): prototype of a zinc-finger family of transcription factors.Q40527459
Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibitionQ40707709
Anthrax lethal factor cleaves the N-terminus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophagesQ41016601
Involvement of MAPK activation in chemokine or COX-2 productions by Toxoplasma gondiiQ42433568
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectToxoplasma gondiiQ131003
P304page(s)e18335
P577publication date2011-03-29
P1433published inPLOS OneQ564954
P1476titleSerum response factor regulates immediate early host gene expression in Toxoplasma gondii-infected host cells
P478volume6

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cites work (P2860)
Q37194952A Toxoplasma dense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation.
Q35842701Gene expression profiles in genetically different mice infected with Toxoplasma gondii: ALDH1A2, BEX2, EGR2, CCL3 and PLAU.
Q34803573Genetic basis for phenotypic differences between different Toxoplasma gondii type I strains
Q37723997Infection by Toxoplasma gondii specifically induces host c-Myc and the genes this pivotal transcription factor regulates
Q36457572Toward a molecular pathogenic pathway for Yersinia pestis YopM.
Q38731005Toxoplasma Effectors Targeting Host Signaling and Transcription
Q35745869Transcriptome Profiles of Human Lung Epithelial Cells A549 Interacting with Aspergillus fumigatus by RNA-Seq
Q35078531Trypanosoma brucei gambiense adaptation to different mammalian sera is associated with VSG expression site plasticity

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