Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS

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Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2014PNAS..111..197I
P356DOI10.1073/PNAS.1320786110
P3181OpenCitations bibliographic resource ID2666061
P932PMC publication ID3890817
P698PubMed publication ID24344300
P5875ResearchGate publication ID259350680

P2093author name stringStuart A Sievers
Magdalena I Ivanova
Michael R Sawaya
P John Hart
David S Eisenberg
Duane D Winkler
Lisa M Johnson
Ahmad Galaleldeen
Elizabeth L Guenther
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Molecular basis for insulin fibril assemblyQ24657505
Atomic structures of amyloid cross-beta spines reveal varied steric zippersQ27644644
Disrupted Zinc-Binding Sites in Structures of Pathogenic SOD1 Variants D124V and H80RQ27662078
Determination and analysis of the 2 A-structure of copper, zinc superoxide dismutaseQ27729237
Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injuryQ28511628
Amyotrophic lateral sclerosisQ29619516
Mutation-dependent polymorphism of Cu,Zn-superoxide dismutase aggregates in the familial form of amyotrophic lateral sclerosisQ33559556
Identifying the amylome, proteins capable of forming amyloid-like fibrilsQ33734407
Immature copper-zinc superoxide dismutase and familial amyotrophic lateral sclerosis.Q33772493
Novel antibodies reveal inclusions containing non-native SOD1 in sporadic ALS patientsQ33996210
An examination of wild-type SOD1 in modulating the toxicity and aggregation of ALS-associated mutant SOD1Q34341120
IL-17A is increased in the serum and in spinal cord CD8 and mast cells of ALS patientsQ34351001
Copper and zinc metallation status of copper-zinc superoxide dismutase from amyotrophic lateral sclerosis transgenic mice.Q34509452
Disulfide-reduced ALS variants of Cu, Zn superoxide dismutase exhibit increased populations of unfolded speciesQ34788369
Molecular biology of amyotrophic lateral sclerosis: insights from geneticsQ36573336
Different regulation of wild-type and mutant Cu,Zn superoxide dismutase localization in mammalian mitochondriaQ36934610
Initiation and elongation in fibrillation of ALS-linked superoxide dismutaseQ36978868
Structural similarity of wild-type and ALS-mutant superoxide dismutase-1 fibrils using limited proteolysis and atomic force microscopyQ36991027
SOD1 aggregation and ALS: role of metallation states and disulfide statusQ38075887
Extracellular aggregated Cu/Zn superoxide dismutase activates microglia to give a cytotoxic phenotype.Q39217852
Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding siteQ44070818
Copper-binding-site-null SOD1 causes ALS in transgenic mice: aggregates of non-native SOD1 delineate a common featureQ44579313
Familial amyotrophic lateral sclerosis with His46Arg mutation in Cu/Zn superoxide dismutase presenting characteristic clinical features and Lewy body-like hyaline inclusionsQ45090366
Dissociation of human copper-zinc superoxide dismutase dimers using chaotrope and reductant. Insights into the molecular basis for dimer stabilityQ45107835
Expression of wild-type human superoxide dismutase-1 in mice causes amyotrophic lateral sclerosisQ48355423
Clinical and functional investigation of 10 missense mutations and a novel frameshift insertion mutation of the gene for copper-zinc superoxide dismutase in UK families with amyotrophic lateral sclerosisQ73144671
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectamyotrophic lateral sclerosisQ206901
P304page(s)197-201
P577publication date2014-01-07
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleAggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS
P478volume111

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