| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Dawn M. Elliott | |
| Nandan L. Nerurkar | |||
| Robert L. Mauck | |||
| P2860 | cites work | United States trends in lumbar fusion surgery for degenerative conditions | Q28256883 |
| Adjacent segment degeneration following spinal fusion for degenerative disc disease | Q28304521 | ||
| Nucleus pulposus tissue engineering: a brief review | Q30434295 | ||
| Novel biodegradable poly(1,8-octanediol malate) for annulus fibrosus regeneration | Q30444202 | ||
| Biphasic scaffold for annulus fibrosus tissue regeneration | Q30444971 | ||
| Extracellular matrix in development of the intervertebral disc. | Q30665753 | ||
| Degeneration affects the fiber reorientation of human annulus fibrosus under tensile load. | Q51436946 | ||
| Tissue engineering of the intervertebral disc with cultured annulus fibrosus cells using atelocollagen honeycomb-shaped scaffold with a membrane seal (ACHMS scaffold). | Q30777807 | ||
| Assessment of compressive modulus, hydraulic permeability and matrix content of trypsin-treated nucleus pulposus using quantitative MRI. | Q30992586 | ||
| Osteogenic protein-1 injection into a degenerated disc induces the restoration of disc height and structural changes in the rabbit anular puncture model | Q31035667 | ||
| An experimental study of the regeneration of the intervertebral disc with an allograft of cultured annulus fibrosus cells using a tissue-engineering method | Q31135433 | ||
| Distinct intervertebral disc cell populations adopt similar phenotypes in three-dimensional culture | Q33603558 | ||
| Engineering orthopedic tissue interfaces | Q33634554 | ||
| Engineering on the straight and narrow: the mechanics of nanofibrous assemblies for fiber-reinforced tissue regeneration. | Q33634560 | ||
| Expression of chondrocyte markers by cells of normal and degenerate intervertebral discs | Q33918947 | ||
| Functional tissue engineering: the role of biomechanics | Q34147577 | ||
| Osmolarity regulates gene expression in intervertebral disc cells determined by gene array and real-time quantitative RT-PCR. | Q34447190 | ||
| Confined compression experiments on bovine nucleus pulposus and annulus fibrosus: sensitivity of the experiment in the determination of compressive modulus and hydraulic permeability. | Q34449910 | ||
| Tissue-engineering approach to regenerating the intervertebral disc | Q34630771 | ||
| Multiaxial Mechanical Behavior of Biological Materials | Q35120926 | ||
| Nutrition of the intervertebral disc | Q35963858 | ||
| Nanofibrous biologic laminates replicate the form and function of the annulus fibrosus | Q36152358 | ||
| Engineered disc-like angle-ply structures for intervertebral disc replacement. | Q36172350 | ||
| Nucleus pulposus replacement: basic science and indications for clinical use. | Q36231717 | ||
| Material properties in unconfined compression of human nucleus pulposus, injectable hyaluronic acid-based hydrogels and tissue engineering scaffolds. | Q36421239 | ||
| Mechanical behavior of the human lumbar spine. I. Creep analysis during static compressive loading | Q36473622 | ||
| What is intervertebral disc degeneration, and what causes it? | Q36568385 | ||
| A comparison of the effects of automated percutaneous diskectomy and conventional diskectomy on intradiscal pressure, disk geometry, and stiffness | Q36725646 | ||
| The Lumbar Disc and Low Back Pain | Q37064356 | ||
| The effect of relative needle diameter in puncture and sham injection animal models of degeneration | Q37111562 | ||
| Engineering controllable anisotropy in electrospun biodegradable nanofibrous scaffolds for musculoskeletal tissue engineering | Q37130496 | ||
| Lumbar disc arthroplasty: a critical review. | Q37173894 | ||
| Intervertebral disc tissue engineering using a novel hyaluronic acid-nanofibrous scaffold (HANFS) amalgam | Q37176606 | ||
| SMAD3 functions as a transcriptional repressor of acid-sensing ion channel 3 (ASIC3) in nucleus pulposus cells of the intervertebral disc | Q37197284 | ||
| Lumbar adjacent segment degeneration and disease after arthrodesis and total disc arthroplasty | Q37204941 | ||
| Tissue engineering and the intervertebral disc: the challenges | Q37324314 | ||
| Culture of human anulus fibrosus cells on polyamide nanofibers: extracellular matrix production | Q37363789 | ||
| Photo-crosslinked alginate hydrogels support enhanced matrix accumulation by nucleus pulposus cells in vivo | Q37366581 | ||
| In vivo remodeling of intervertebral discs in response to short- and long-term dynamic compression | Q37375511 | ||
| Frequency-dependent behavior of the intervertebral disc in response to each of six degree of freedom dynamic loading: solid phase and fluid phase contributions. | Q37377921 | ||
| Biomimetic stratified scaffold design for ligament-to-bone interface tissue engineering | Q37550615 | ||
| Effect of strain rate on tensile properties of sheep disc anulus fibrosus. | Q51594832 | ||
| Spatial and structural dependence of mechanical properties of porcine intervertebral disc. | Q51621968 | ||
| A nonlinear hyperelastic mixture theory model for anisotropy, transport, and swelling of annulus fibrosus. | Q51712070 | ||
| Recombinant osteogenic protein-1 upregulates extracellular matrix metabolism by rabbit annulus fibrosus and nucleus pulposus cells cultured in alginate beads. | Q51836252 | ||
| Shear mechanical properties of human lumbar annulus fibrosus. | Q52136583 | ||
| Role of actin stress fibres in the development of the intervertebral disc: cytoskeletal control of extracellular matrix assembly. | Q52175944 | ||
| Biomechanics of load-bearing of the intervertebral disc: an experimental and finite element model. | Q52271795 | ||
| Effects of degeneration on the elastic modulus distribution in the lumbar intervertebral disc. | Q52307361 | ||
| Mechanical behavior of a simple model of an intervertebral disk under compressive loading. | Q52767010 | ||
| Degenerative anular changes induced by puncture are associated with insufficiency of disc biomechanical function. | Q53510195 | ||
| The effect of serial monolayer passaging on the collagen expression profile of outer and inner anulus fibrosus cells. | Q53603967 | ||
| Nonlinear stress analysis of the whole lumbar spine in torsion--mechanics of facet articulation. | Q54213025 | ||
| Enhancing annulus fibrosus tissue formation in porous silk scaffolds | Q57219267 | ||
| Laboratory Conditions for Tensile Tests in Annulus Fibrosus from Human Intervertebral Discs | Q58260451 | ||
| Adenovirus-mediated gene transfer to nucleus pulposus cells. Implications for the treatment of intervertebral disc degeneration | Q64381801 | ||
| Lumbar disc degeneration: correlation with age, sex, and spine level in 600 autopsy specimens | Q68478106 | ||
| Investigation of the laminate structure of lumbar disc anulus fibrosus | Q68837455 | ||
| Biaxial mechanical behavior of excised ventricular epicardium | Q68864216 | ||
| Hierarchical structure of the intervertebral disc | Q69459488 | ||
| Ultrastructure of the human intervertebral disc. I. Changes in notochordal cells with age | Q70680494 | ||
| Tensile properties of nondegenerate human lumbar anulus fibrosus | Q71134655 | ||
| Allografting intervertebral discs in dogs: a possible clinical application | Q71292513 | ||
| Confined compression of canine annulus fibrosus under chemical and mechanical loading | Q71369605 | ||
| Regional variation in tensile properties and biochemical composition of the human lumbar anulus fibrosus | Q72142140 | ||
| Compressive mechanical properties of the human anulus fibrosus and their relationship to biochemical composition | Q72353980 | ||
| Stress Analysis of the Lumbar Disc-Body Unit in Compression A Three-Dimensional Nonlinear Finite Element Study | Q72816464 | ||
| Flexibility of lumbar spinal motion segments correlated to type of tears in the annulus fibrosus | Q73313696 | ||
| Biaxial mechanical properties of the natural and glutaraldehyde treated aortic valve cusp--Part I: Experimental results | Q73735649 | ||
| The viscoelastic behavior of the non-degenerate human lumbar nucleus pulposus in shear | Q73927624 | ||
| Anisotropic and inhomogeneous tensile behavior of the human anulus fibrosus: experimental measurement and material model predictions | Q74281544 | ||
| Characterization and phenotypic stability of human disc cells in vitro | Q74311778 | ||
| Fluid flow and convective transport of solutes within the intervertebral disc | Q75223401 | ||
| Degeneration affects the anisotropic and nonlinear behaviors of human anulus fibrosus in compression | Q77355012 | ||
| An atelocollagen honeycomb-shaped scaffold with a membrane seal (ACHMS-scaffold) for the culture of annulus fibrosus cells from an intervertebral disc | Q78776062 | ||
| Effects of swelling pressure and hydraulic permeability on dynamic compressive behavior of lumbar annulus fibrosus | Q78829682 | ||
| Comparison of animals used in disc research to human lumbar disc geometry | Q79702074 | ||
| Nucleus pulposus glycosaminoglycan content is correlated with axial mechanics in rat lumbar motion segments | Q79979388 | ||
| MEK/ERK signaling controls osmoregulation of nucleus pulposus cells of the intervertebral disc by transactivation of TonEBP/OREBP | Q79981860 | ||
| Effect of bone morphogenetic protein-2 (BMP-2) on matrix production, other BMPs, and BMP receptors in rat intervertebral disc cells | Q80601733 | ||
| Experimental intervertebral disc degeneration induced by chondroitinase ABC in the goat | Q80971510 | ||
| Single lamellar mechanics of the human lumbar anulus fibrosus | Q81547493 | ||
| Effects of degeneration on the biphasic material properties of human nucleus pulposus in confined compression | Q82054802 | ||
| Polar surface chemistry of nanofibrous polyurethane scaffold affects annulus fibrosus cell attachment and early matrix accumulation | Q83082471 | ||
| Serum-free, chemically defined medium with TGF-beta(3) enhances functional properties of nucleus pulposus cell-laden carboxymethylcellulose hydrogel constructs | Q84583955 | ||
| Factors involved in the nutrition of the human lumbar intervertebral disc: cellularity and diffusion of glucose in vitro | Q39223995 | ||
| Biomechanical comparison between fusion of two vertebrae and implantation of an artificial intervertebral disc | Q40355504 | ||
| Young investigator award winner: validation of the mouse and rat disc as mechanical models of the human lumbar disc | Q40516987 | ||
| Cell shape and gene expression in human intervertebral disc cells: in vitro tissue engineering studies | Q40557304 | ||
| Proteoglycans synthesized by canine intervertebral disc cells grown in a type I collagen-glycosaminoglycan matrix | Q40609096 | ||
| Finite deformation biphasic material properties of bovine articular cartilage from confined compression experiments | Q40870803 | ||
| Degeneration and aging affect the tensile behavior of human lumbar anulus fibrosus. | Q40962212 | ||
| Is the nucleus pulposus a solid or a fluid? Mechanical behaviors of the nucleus pulposus of the human intervertebral disc. | Q41051067 | ||
| A poroelastic-swelling finite element model with application to the intervertebral disc | Q41083509 | ||
| Mechanical properties of human lumbar spine motion segments. Influence of age, sex, disc level, and degeneration | Q41521993 | ||
| Application of a fiber-reinforced continuum theory to multiple deformations of the annulus fibrosus | Q41688960 | ||
| A special theory of biphasic mixtures and experimental results for human annulus fibrosus tested in confined compression | Q41738733 | ||
| Investigation of nano-mechanical properties of annulus fibrosus using atomic force microscopy | Q41871423 | ||
| Porous silk scaffolds can be used for tissue engineering annulus fibrosus | Q41910998 | ||
| Inclusion of regional poroelastic material properties better predicts biomechanical behavior of lumbar discs subjected to dynamic loading | Q41997559 | ||
| ISSLS prize winner: integrating theoretical and experimental methods for functional tissue engineering of the annulus fibrosus | Q42286059 | ||
| X-ray diffraction studies of the arrangement of collagenous fibres in human fetal intervertebral disc. | Q42535928 | ||
| Developing an alginate/chitosan hybrid fiber scaffold for annulus fibrosus cells | Q42830557 | ||
| The effect of nanofiber alignment on the maturation of engineered meniscus constructs. | Q42861878 | ||
| Evaluation criteria for musculoskeletal and craniofacial tissue engineering constructs: a conference report | Q42932612 | ||
| Collagen gene expression and mechanical properties of intervertebral disc cell-alginate cultures | Q43595027 | ||
| Intervertebral disc cells exhibit differences in gene expression in alginate and monolayer culture | Q43700372 | ||
| Radial tensile properties of the lumbar annulus fibrosus are site and degeneration dependent | Q43891970 | ||
| Theoretical model and experimental results for the nonlinear elastic behavior of human annulus fibrosus | Q44037658 | ||
| The potential and limitations of a cell-seeded collagen/hyaluronan scaffold to engineer an intervertebral disc-like matrix | Q44342972 | ||
| Comparison of animal discs used in disc research to human lumbar disc: axial compression mechanics and glycosaminoglycan content | Q44378187 | ||
| Biomechanical evaluation of lumbar spinal stability after graded facetectomies. | Q44523600 | ||
| Fresh frozen intervertebral disc allografting in a bipedal animal model | Q44564252 | ||
| Intervertebral disc cell therapy for regeneration: mesenchymal stem cell implantation in rat intervertebral discs | Q44850558 | ||
| Tissue-engineered composites of anulus fibrosus and nucleus pulposus for intervertebral disc replacement | Q44929532 | ||
| Mechanical behavior of the human annulus fibrosus | Q45250520 | ||
| Characterization of novel photocrosslinked carboxymethylcellulose hydrogels for encapsulation of nucleus pulposus cells. | Q45978039 | ||
| Biaxial testing of human annulus fibrosus and its implications for a constitutive formulation | Q46126652 | ||
| Characterization of photocrosslinked alginate hydrogels for nucleus pulposus cell encapsulation | Q46374334 | ||
| Anisotropic shear behavior of the annulus fibrosus: effect of harvest site and tissue prestrain. | Q46572550 | ||
| The potential of chitosan-based gels containing intervertebral disc cells for nucleus pulposus supplementation | Q46672147 | ||
| Biomechanical and biochemical characterization of composite tissue-engineered intervertebral discs | Q46705490 | ||
| Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment | Q46891204 | ||
| Effect of position and height of a mobile core type artificial disc on the biomechanical behaviour of the lumbar spine. | Q47236069 | ||
| ISSLS prize winner: microstructure and mechanical disruption of the lumbar disc annulus: part I: a microscopic investigation of the translamellar bridging network | Q47240809 | ||
| Rheological characterization of the nucleus pulposus and dense collagen scaffolds intended for functional replacement | Q47247333 | ||
| Restoration of disc height loss by recombinant human osteogenic protein-1 injection into intervertebral discs undergoing degeneration induced by an intradiscal injection of chondroitinase ABC. | Q47288761 | ||
| Mechanisms for mechanical damage in the intervertebral disc annulus fibrosus. | Q47304175 | ||
| Tissue engineered nucleus pulposus tissue formed on a porous calcium polyphosphate substrate. | Q47369703 | ||
| Quantifying the contributions of structure to annulus fibrosus mechanical function using a nonlinear, anisotropic, hyperelastic model | Q48421886 | ||
| In vitro studies of annulus fibrosus disc cell attachment, differentiation and matrix production on PDLLA/45S5 Bioglass composite films. | Q50478329 | ||
| Development of controlled matrix heterogeneity on a triphasic scaffold for orthopedic interface tissue engineering. | Q50998188 | ||
| Occupational and genetic risk factors associated with intervertebral disc disease. | Q51014820 | ||
| Mechanics of oriented electrospun nanofibrous scaffolds for annulus fibrosus tissue engineering. | Q51018409 | ||
| Transplantation of mesenchymal stem cells embedded in Atelocollagen gel to the intervertebral disc: a potential therapeutic model for disc degeneration. | Q51023294 | ||
| Polyethylene wear debris and long-term clinical failure of the Charité disc prosthesis: a study of 4 patients. | Q51083769 | ||
| Design and analysis of tissue engineering scaffolds that mimic soft tissue mechanical anisotropy. | Q51245248 | ||
| Intralamellar relationships within the collagenous architecture of the annulus fibrosus imaged in its fully hydrated state. | Q51347559 | ||
| Formation of a nucleus pulposus-cartilage endplate construct in vitro. | Q51360932 | ||
| A homogenization model of the annulus fibrosus. | Q51433748 | ||
| P433 | issue | 6 | |
| P921 | main subject | tissue engineering | Q1540285 |
| P304 | page(s) | 1017-30 | |
| P577 | publication date | 2010-04-19 | |
| P1433 | published in | Journal of Biomechanics | Q4862281 |
| P1476 | title | Mechanical design criteria for intervertebral disc tissue engineering | |
| P478 | volume | 43 |
| Q77790047 | A dynamic radiographic imaging study of lumbar intervertebral disc morphometry and deformation in vivo |
| Q37075958 | Analysis of quantitative magnetic resonance imaging and biomechanical parameters on human discs with different grades of degeneration |
| Q43484391 | Biaxial mechanics and inter-lamellar shearing of stem-cell seeded electrospun angle-ply laminates for annulus fibrosus tissue engineering |
| Q39190870 | Biomaterials for intervertebral disc regeneration and repair |
| Q64068586 | Biomechanical comparison of percutaneous posterior endoscopic cervical discectomy and anterior cervical decompression and fusion on the treatment of cervical spondylotic radiculopathy |
| Q33733279 | Biomechanics and mechanobiology in functional tissue engineering |
| Q47745012 | Biomimetic nanofibers can construct effective tissue-engineered intervertebral discs for therapeutic implantation |
| Q48273530 | Biomimetic nucleus pulposus scaffold created from bovine caudal intervertebral disc tissue utilizing an optimal decellularization procedure |
| Q47858072 | Bioreactors with hydrostatic pressures imitating physiological environments in intervertebral discs. |
| Q26829807 | Challenges and strategies in the repair of ruptured annulus fibrosus |
| Q44794590 | Characterization of injectable hydrogels based on poly(N-isopropylacrylamide)-g-chondroitin sulfate with adhesive properties for nucleus pulposus tissue engineering |
| Q90431486 | Ciliary parathyroid hormone signaling activates transforming growth factor-β to maintain intervertebral disc homeostasis during aging |
| Q89783831 | Current Treatment Options for Intervertebral Disc Pathologies |
| Q52670101 | Cyclic mechanical tension reinforces DNA damage and activates the p53-p21-Rb pathway to induce premature senescence of nucleus pulposus cells. |
| Q88409983 | Decellularization and characterization of a whole intervertebral disk xenograft scaffold |
| Q37814771 | Degeneration and regeneration of the intervertebral disc: lessons from development |
| Q28392944 | Design Requirements for Annulus Fibrosus Repair: Review of Forces, Displacements, and Material Properties of the Intervertebral Disk and a Summary of Candidate Hydrogels for Repair |
| Q50789411 | Differentiation of adipose stem cells seeded towards annulus fibrosus cells on a designed poly(trimethylene carbonate) scaffold prepared by stereolithography. |
| Q91714413 | Disordered Mechanical Stress and Tissue Engineering Therapies in Intervertebral Disc Degeneration |
| Q33717664 | Elastic, permeability and swelling properties of human intervertebral disc tissues: A benchmark for tissue engineering |
| Q35886192 | Ex vivo observation of human intervertebral disc tissue and cells isolated from degenerated intervertebral discs |
| Q64069601 | Exogenous Delivery of Link N mRNA into Chondrocytes and MSCs-The Potential Role in Increasing Anabolic Response |
| Q42082376 | Fabrication and mechanical evaluation of anatomically-inspired quasilaminate hydrogel structures with layer-specific formulations. |
| Q35566891 | Fiber angle and aspect ratio influence the shear mechanics of oriented electrospun nanofibrous scaffolds |
| Q57393634 | Fiber-Assisted Molding (FAM) of Surfaces with Tunable Curvature to Guide Cell Alignment and Complex Tissue Architecture |
| Q53480891 | Functional nucleus pulposus-like matrix assembly by human mesenchymal stromal cells is directed by macromer concentration in photocrosslinked carboxymethylcellulose hydrogels. |
| Q41536307 | Homologous structure-function relationships between native fibrocartilage and tissue engineered from MSC-seeded nanofibrous scaffolds |
| Q37954579 | Hydrogels in acellular and cellular strategies for intervertebral disc regeneration. |
| Q48595223 | Imaging Cell Viability on Non-transparent Scaffolds - Using the Example of a Novel Knitted Titanium Implant |
| Q43991738 | In vivo multifrequency magnetic resonance elastography of the human intervertebral disk |
| Q41693930 | Injectable, high-density collagen gels for annulus fibrosus repair: An in vitro rat tail model |
| Q37871995 | Intervertebral disc properties: challenges for biodevices. |
| Q61818208 | Materials for the Spine: Anatomy, Problems, and Solutions |
| Q38761799 | Mechanical function near defects in an aligned nanofiber composite is preserved by inclusion of disorganized layers: Insight into meniscus structure and function |
| Q38116401 | Mechanical loading of the intervertebral disc: from the macroscopic to the cellular level. |
| Q39245619 | Meniscus, articular cartilage and nucleus pulposus: a comparative review of cartilage-like tissues in anatomy, development and function |
| Q36995489 | Microscale fiber network alignment affects macroscale failure behavior in simulated collagen tissue analogs |
| Q37188424 | Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs. |
| Q36996310 | N-cadherin is Key to Expression of the Nucleus Pulposus Cell Phenotype under Selective Substrate Culture Conditions |
| Q44822753 | Numerical evaluation of the correlation between the normal variation in the sagittal alignment of the lumbar spine and the spinal loads. |
| Q57917839 | On the Experimental Intradiscal Pressure Measurement Techniques: A Review |
| Q52325002 | Physiology and Engineering of the Graded Interfaces of Musculoskeletal Junctions. |
| Q92970196 | Promise, progress, and problems in whole disc tissue engineering |
| Q36352488 | Regenerating nucleus pulposus of the intervertebral disc using biodegradable nanofibrous polymer scaffolds |
| Q28540801 | Regional variations in the cellular, biochemical, and biomechanical characteristics of rabbit annulus fibrosus |
| Q39437875 | Rheological and mechanical properties of acellular and cell-laden methacrylated gellan gum hydrogels |
| Q38078104 | Role of biomechanics in intervertebral disc degeneration and regenerative therapies: what needs repairing in the disc and what are promising biomaterials for its repair? |
| Q41846384 | Screening of hyaluronic acid-poly(ethylene glycol) composite hydrogels to support intervertebral disc cell biosynthesis using artificial neural network analysis |
| Q47215487 | Silk-based multilayered angle-ply annulus fibrosus construct to recapitulate form and function of the intervertebral disc |
| Q38840657 | Structure and mechanical function of the inter-lamellar matrix of the annulus fibrosus in the disc. |
| Q39108596 | Surgical repair of annulus defect with biomimetic multilamellar nano/microfibrous scaffold in a porcine model |
| Q42684285 | Synthesis of Thermogelling Poly(N-isopropylacrylamide)-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering. |
| Q40008387 | The distribution of fibrillin-2 and LTBP-2, and their co-localisation with fibrillin-1 in adult bovine tail disc |
| Q90644788 | The transcription factors regulating intervertebral disc development |
| Q31036347 | Theory of MRI contrast in the annulus fibrosus of the intervertebral disc |
| Q35151962 | Thermogelling bioadhesive scaffolds for intervertebral disk tissue engineering: preliminary in vitro comparison of aldehyde-based versus alginate microparticle-mediated adhesion |
| Q91999009 | Tissue Engineering Strategies for Intervertebral Disc Treatment Using Functional Polymers |
| Q26774889 | Tissue Engineering a Biological Repair Strategy for Lumbar Disc Herniation |
| Q35164708 | Tissue-engineered intervertebral discs produce new matrix, maintain disc height, and restore biomechanical function to the rodent spine |
| Q51675279 | Translational challenges for the development of a novel nucleus pulposus substitute: Experimental results from biomechanical and in vivo studies. |
| Q92970150 | Viscoelastic heating of insulated bovine intervertebral disc |
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