The crystal structure of BlmI as a model for nonribosomal peptide synthetase peptidyl carrier proteins

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The crystal structure of BlmI as a model for nonribosomal peptide synthetase peptidyl carrier proteins is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/PROT.24485
P3181OpenCitations bibliographic resource ID4482142
P932PMC publication ID4109001
P698PubMed publication ID25050442

P50authorAndrzej JoachimiakQ28028611
Jeremy R. LohmanQ78377036
George N PhillipsQ95337388
P2093author name stringBen Shen
Ming Ma
Gyorgy Babnigg
Lance Bigelow
Marianne E Cuff
Jessica Bearden
P2860cites workMUSCLE: multiple sequence alignment with high accuracy and high throughputQ24613456
MolProbity: all-atom structure validation for macromolecular crystallographyQ24649111
Solution structure of PCP, a prototype for the peptidyl carrier domains of modular peptide synthetasesQ27622440
Biosynthesis of D-alanyl-lipoteichoic acid: the tertiary structure of apo-D-alanyl carrier proteinQ27632900
Structural and functional insights into a peptide bond-forming bidomain from a nonribosomal peptide synthetaseQ27646796
Crystal structure of the termination module of a nonribosomal peptide synthetaseQ27650957
Dynamic thiolation–thioesterase structure of a non-ribosomal peptide synthetaseQ27651612
Structural basis for the selectivity of the external thioesterase of the surfactin synthetaseQ27651615
Structural Basis for Phosphopantetheinyl Carrier Domain Interactions in the Terminal Module of Nonribosomal Peptide SynthetasesQ27675813
Structural and Functional Investigation of the Intermolecular Interaction between NRPS Adenylation and Carrier Protein DomainsQ27677481
Structure of PA1221, a Nonribosomal Peptide Synthetase Containing Adenylation and Peptidyl Carrier Protein DomainsQ27678231
Inference of macromolecular assemblies from crystalline stateQ27860457
HKL-3000: the integration of data reduction and structure solution--from diffraction images to an initial model in minutesQ27860502
Coot: model-building tools for molecular graphicsQ27860505
Searching protein structure databases with DaliLite v.3Q27860638
ESPript: analysis of multiple sequence alignments in PostScriptQ27860708
Overview of the CCP4 suite and current developmentsQ27860782
MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony MethodsQ27860929
Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7Q27860936
Refinement of macromolecular structures by the maximum-likelihood methodQ27861011
Calculation of protein extinction coefficients from amino acid sequence dataQ27861073
Twilight zone of protein sequence alignmentsQ29614388
Ligation-independent cloning of PCR products (LIC-PCR)Q29618962
High-throughput protein purification and quality assessment for crystallizationQ30406950
Project management system for structural and functional proteomics: SesameQ30787059
A protein interaction surface in nonribosomal peptide synthesis mapped by combinatorial mutagenesis and selectionQ33237794
Interdomain communication between the thiolation and thioesterase domains of EntF explored by combinatorial mutagenesis and selectionQ33255195
Assembly-line enzymology for polyketide and nonribosomal Peptide antibiotics: logic, machinery, and mechanisms.Q34555236
Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesisQ36862015
A free-standing condensation enzyme catalyzing ester bond formation in C-1027 biosynthesisQ37132922
A family of LIC vectors for high-throughput cloning and purification of proteinsQ37408286
An expression vector tailored for large-scale, high-throughput purification of recombinant proteinsQ37471293
The structural role of the carrier protein--active controller or passive carrierQ38038812
Cloning and sequencing of the kedarcidin biosynthetic gene cluster from Streptoalloteichus sp. ATCC 53650 revealing new insights into biosynthesis of the enediyne family of antitumor antibiotics.Q38455653
Stoichiometry and specificity of in vitro phosphopantetheinylation and aminoacylation of the valine-activating module of surfactin synthetaseQ40868475
Identification and characterization of a type II peptidyl carrier protein from the bleomycin producer Streptomyces verticillus ATCC 15003.Q41681873
Biosynthesis of the beta-amino acid moiety of the enediyne antitumor antibiotic C-1027 featuring beta-amino acyl-S-carrier protein intermediatesQ46653695
Evidence for a protein-protein interaction motif on an acyl carrier protein domain from a modular polyketide synthaseQ48547204
Structure of apo acyl carrier protein and a proposal to engineer protein crystallization through metal ions.Q51626317
Localized protein interaction surfaces on the EntB carrier protein revealed by combinatorial mutagenesis and selection.Q54457270
Structure of the EntB multidomain nonribosomal peptide synthetase and functional analysis of its interaction with the EntE adenylation domain.Q54466416
High throughput methods for gene cloning and expression.Q54543520
Conformational Switches Modulate Protein Interactions in Peptide Antibiotic SynthetasesQ57903771
Biochemical characterization of peptidyl carrier protein (PCP), the thiolation domain of multifunctional peptide synthetasesQ71824474
Chain initiation in the leinamycin-producing hybrid nonribosomal peptide/polyketide synthetase from Streptomyces atroolivaceus S-140. Discrete, monofunctional adenylation enzyme and peptidyl carrier protein that directly load D-alanineQ80335891
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectcrystal structureQ895901
P304page(s)1210-8
P577publication date2014-07-01
P1433published inProteinsQ7251514
P1476titleThe crystal structure of BlmI as a model for nonribosomal peptide synthetase peptidyl carrier proteins
P478volume82

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cites work (P2860)
Q34499818Crystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892
Q27701584High-resolution structures of the D-alanyl carrier protein (Dcp) DltC from Bacillus subtilis reveal equivalent conformations of apo- and holo-forms
Q64240372Insights into Thiotemplated Pyrrole Biosynthesis Gained from the Crystal Structure of Flavin-Dependent Oxidase in Complex with Carrier Protein
Q36599498Loop dynamics of thymidine diphosphate-rhamnose 3'-O-methyltransferase (CalS11), an enzyme in calicheamicin biosynthesis
Q28075494New Structural Data Reveal the Motion of Carrier Proteins in Nonribosomal Peptide Synthesis
Q34074552Probing the phosphopantetheine arm conformations of acyl carrier proteins using vibrational spectroscopy
Q36398859Solution Structure of a Nonribosomal Peptide Synthetase Carrier Protein Loaded with Its Substrate Reveals Transient, Well-Defined Contacts
Q36597567Structural Biology of Nonribosomal Peptide Synthetases
Q33733616Structural and bioinformatic characterization of an Acinetobacter baumannii type II carrier protein
Q90242836Structural basis for chain release from the enacyloxin polyketide synthase
Q40718758Structure and Substrate Sequestration in the Pyoluteorin Type II Peptidyl Carrier Protein PltL
Q27697457Structure of the terminal PCP domain of the non-ribosomal peptide synthetase in teicoplanin biosynthesis
Q36607621Structure-based analysis of the molecular interactions between acyltransferase and acyl carrier protein in vicenistatin biosynthesis.
Q27703606Synthetic cycle of the initiation module of a formylating nonribosomal peptide synthetase
Q38568948The structural biology of biosynthetic megaenzymes
Q90587824Type II non-ribosomal peptide synthetase proteins: structure, mechanism, and protein-protein interactions

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