Multivalent Interactions by the Set8 Histone Methyltransferase With Its Nucleosome Substrate

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Multivalent Interactions by the Set8 Histone Methyltransferase With Its Nucleosome Substrate is …
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scholarly articleQ13442814

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P356DOI10.1016/J.JMB.2016.02.025
P3181OpenCitations bibliographic resource ID3385857
P932PMC publication ID5549631
P698PubMed publication ID26953260

P2093author name stringSong Tan
Robert K McGinty
Taverekere S Girish
P2860cites workSpecificity and mechanism of the histone methyltransferase Pr-Set7.Q24304412
Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferaseQ24529594
PR-Set7 and H4K20me1: at the crossroads of genome integrity, cell cycle, chromosome condensation, and transcriptionQ26823191
The effect of H3K79 dimethylation and H4K20 trimethylation on nucleosome and chromatin structureQ27652164
Structure of RCC1 chromatin factor bound to the nucleosome core particleQ27664183
The MBT Repeats of L3MBTL1 Link SET8-mediated p53 Methylation at Lysine 382 to Target Gene RepressionQ27664677
Structural Basis of Silencing: Sir3 BAH Domain in Complex with a Nucleosome at 3.0 Å ResolutionQ27675642
A Conserved Mechanism for Centromeric Nucleosome Recognition by Centromere Protein CENP-CQ27678426
Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNAQ27733704
Overview of the CCP4 suite and current developmentsQ27860782
Phasercrystallographic softwareQ27860930
Refinement of macromolecular structures by the maximum-likelihood methodQ27861011
Latest methods of fluorescence-based protein crystal identificationQ28087575
SET8 is degraded via PCNA-coupled CRL4(CDT2) ubiquitylation in S phase and after UV irradiationQ28302907
PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatinQ28647369
SET domain protein lysine methyltransferases: Structure, specificity and catalysis.Q30159622
Strategies for crystallizing a chromatin protein in complex with the nucleosome core particleQ30409526
CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradationQ30430339
Regulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damageQ33733896
Histone modifying enzymes: structures, mechanisms, and specificitiesQ33761580
Expression and purification of recombinant histones and nucleosome reconstitutionQ33914576
Purification and functional characterization of SET8, a nucleosomal histone H4-lysine 20-specific methyltransferaseQ34139275
The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells.Q34144213
Substrate and product specificities of SET domain methyltransferasesQ34208487
CRL4Cdt2-Mediated Destruction of the Histone Methyltransferase Set8 Prevents Premature Chromatin Compaction in S PhaseQ34215301
Histone H4 Lysine 20 methylation: key player in epigenetic regulation of genomic integrityQ34647591
Nucleosome acidic patch promotes RNF168- and RING1B/BMI1-dependent H2AX and H2A ubiquitination and DNA damage signaling.Q35113119
Structural Mechanisms of Nucleosome Recognition by Linker Histones.Q35987539
Aberrant monomethylation of histone H4 lysine 20 activates the DNA damage checkpoint in Drosophila melanogasterQ36117699
Post-crystallization treatments for improving diffraction quality of protein crystals.Q36244741
The histone methyltransferase SET8 is required for S-phase progressionQ36639133
PR-Set7-dependent lysine methylation ensures genome replication and stability through S phaseQ36639143
Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse developmentQ37145387
The multiple facets of histone H4-lysine 20 methylationQ37398622
A new regulator of the cell cycle: the PR-Set7 histone methyltransferaseQ37825723
Coupling mitosis to DNA replication: the emerging role of the histone H4-lysine 20 methyltransferase PR-Set7.Q37883700
SET8 methyltransferase activity during the DNA double-strand break response is required for recruitment of 53BP1.Q38953670
Catalytic function of the PR-Set7 histone H4 lysine 20 monomethyltransferase is essential for mitotic entry and genomic stabilityQ39680313
The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus LANA.Q40318272
Trace fluorescent labeling for protein crystallizationQ41138994
SETting the clock for histone H4 monomethylationQ41195886
Crystal structure of the PRC1 ubiquitylation module bound to the nucleosomeQ42001356
Trace fluorescent labeling for high-throughput crystallographyQ43247747
Cell cycle: Disposing of SETD8.Q53287654
The pST44 polycistronic expression system for producing protein complexes in Escherichia coliQ53625100
Quantifying chromatin-associated interactions: the HI-FI systemQ84838486
Nucleosome structure and functionQ86246092
P4510describes a project that usesImageQuantQ112270642
P433issue8
P407language of work or nameEnglishQ1860
P1104number of pages13
P304page(s)1531-1543
P577publication date2016-03-04
P1433published inJournal of Molecular BiologyQ925779
P1476titleMultivalent Interactions by the Set8 Histone Methyltransferase With Its Nucleosome Substrate
P478volume428

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cites work (P2860)
Q90149929A key to unlocking chromatin revealed by complex structures
Q49367973A systematic analysis of nucleosome core particle and nucleosome-nucleosome stacking structure
Q64927759Asymmetry between the two acidic patches dictates the direction of nucleosome sliding by the ISWI chromatin remodeler.
Q47729663Controlling the supramolecular assembly of nucleosomes asymmetrically modified on H4.
Q39350728Cryo-electron microscopy of chromatin biology.
Q57799531Molecular basis for chromatin assembly and modification by multi-protein complexes
Q100693814Multivalent interactions drive nucleosome binding and efficient chromatin deacetylation by SIRT6
Q38895557Progress in the Development of Lysine Methyltransferase SETD8 Inhibitors.
Q51022048Residues in the Nucleosome Acidic Patch Regulate Histone Occupancy and Are Important for FACT Binding in Saccharomyces cerevisiae
Q28079964The emerging role of lysine methyltransferase SETD8 in human diseases
Q64389511Understanding the Histone DNA Repair Code: H4K20me2 Makes Its Mark

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