A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme

scientific article

A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.JSB.2016.09.011
P3181OpenCitations bibliographic resource ID3478834
P932PMC publication ID5131612
P698PubMed publication ID27650958

P50authorTitia SixmaQ21402771
P2093author name stringAlexander Fish
Shreya Dharadhar
Marcello Clerici
Willem J van Dijk
P2860cites workHuman USP3 is a chromatin modifier required for S phase progression and genome stabilityQ24299488
A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathwayQ24303605
Defining the human deubiquitinating enzyme interaction landscapeQ24315885
UAF1 is a subunit of multiple deubiquitinating enzyme complexesQ24329003
The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradationQ24337922
Determination of domain structure of proteins from X-ray solution scatteringQ24537462
PHENIX: a comprehensive Python-based system for macromolecular structure solutionQ24654617
Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehydeQ27640257
Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetaseQ27674789
Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTERQ27678523
Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46Q27702184
Inference of macromolecular assemblies from crystalline stateQ27860457
XDSQ27860472
Overview of the CCP4 suite and current developmentsQ27860782
Phasercrystallographic softwareQ27860930
Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7Q27860936
Refinement of macromolecular structures by the maximum-likelihood methodQ27861011
Features and development of CootQ27861079
iMOSFLM: a new graphical interface for diffraction-image processing with MOSFLMQ27861099
A human interactome in three quantitative dimensions organized by stoichiometries and abundancesQ27936244
Regulation of monoubiquitinated PCNA by DUB autocleavageQ28115531
WDR20 regulates activity of the USP12 x UAF1 deubiquitinating enzyme complexQ28115820
WD repeat protein WDR48 in complex with deubiquitinase USP12 suppresses Akt-dependent cell survival signaling by stabilizing PH domain leucine-rich repeat protein phosphatase 1 (PHLPP1)Q28116016
Allosteric Activation of Ubiquitin-Specific Proteases by β-Propeller Proteins UAF1 and WDR20Q28117407
Breaking the chains: structure and function of the deubiquitinasesQ28131738
Behavioral characteristics of ubiquitin-specific peptidase 46-deficient miceQ28507136
USP1 deubiquitinates ID proteins to preserve a mesenchymal stem cell program in osteosarcomaQ28594596
Usp12 stabilizes the T-cell receptor complex at the cell surface during signalingQ28941247
The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathwayQ29616746
Lysine 92 amino acid residue of USP46, a gene associated with 'behavioral despair' in mice, influences the deubiquitinating enzyme activityQ34063679
A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses.Q34089593
Protein-protein interactions: general trends in the relationship between binding affinity and interfacial buried surface areaQ34326668
Regulation of histone H2A and H2B deubiquitination and Xenopus development by USP12 and USP46.Q34606198
The PDB_REDO server for macromolecular structure model optimizationQ35215523
Serine phosphorylation is critical for the activation of ubiquitin-specific protease 1 and its interaction with WD40-repeat protein UAF1.Q36743136
Deubiquitylases from genes to organismQ38125278
Layers of DUB regulation.Q38527531
DAMMIF, a program for rapid ab-initio shape determination in small-angle scatteringQ39388340
Enabling high-throughput ligation-independent cloning and protein expression for the family of ubiquitin specific proteasesQ39567597
Structure-function analysis of USP1: insights into the role of Ser313 phosphorylation site and the effect of cancer-associated mutations on autocleavage.Q41285125
The DUSP-Ubl domain of USP4 enhances its catalytic efficiency by promoting ubiquitin exchangeQ42028148
The Differential Modulation of USP Activity by Internal Regulatory Domains, Interactors and Eight Ubiquitin Chain TypesQ64166837
A noncanonical cysteine protease USP1 is activated through active site modulation by USP1-associated factor 1Q83726786
P433issue3
P304page(s)437-447
P577publication date2016-09-17
P1433published inJournal of Structural BiologyQ3186947
P1476titleA conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme
P478volume196

Reverse relations

cites work (P2860)
Q47160528Characterization of the deubiquitination activity and substrate specificity of the chicken ubiquitin-specific protease 1/USP associated factor 1 complex.
Q47137280Function of the Deubiquitinating Enzyme USP46 in the Nervous System and Its Regulation by WD40-Repeat Proteins
Q62612784Molecular mechanism of the TP53-MDM2-AR-AKT signalling network regulation by USP12
Q90838642Structural insights into the activation of USP46 by WDR48 and WDR20
Q55129906The novel anti-androgen candidate galeterone targets deubiquitinating enzymes, USP12 and USP46, to control prostate cancer growth and survival.
Q58690927The structure of the deubiquitinase USP15 reveals a misaligned catalytic triad and an open ubiquitin-binding channel
Q49185754USP48 restrains resection by site-specific cleavage of the BRCA1 ubiquitin mark from H2A.

Search more.