| scholarly article | Q13442814 |
| P50 | author | Grzegorz Bujacz | Q28321229 |
| P2093 | author name string | A Wlodawer | |
| M Jaskólski | |||
| A M Skalka | |||
| G Merkel | |||
| J Alexandratos | |||
| R A Katz | |||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 333-46 | |
| P577 | publication date | 1995-10-20 | |
| P1433 | published in | Journal of Molecular Biology | Q925779 |
| P1476 | title | High-resolution structure of the catalytic domain of avian sarcoma virus integrase | |
| P478 | volume | 253 |
| Q27671859 | A Crystal Structure of the Catalytic Core Domain of an Avian Sarcoma and Leukemia Virus Integrase Suggests an Alternate Dimeric Assembly |
| Q40969466 | A high-throughput assay for Tn5 Tnp-induced DNA cleavage |
| Q33887922 | A large nucleoprotein assembly at the ends of the viral DNA mediates retroviral DNA integration |
| Q73442728 | A metal-induced conformational change and activation of HIV-1 integrase |
| Q45767436 | A synthetic peptide from the human immunodeficiency virus type-1 integrase exhibits coiled-coil properties and interferes with the in vitro integration activity of the enzyme. Correlated biochemical and spectroscopic results |
| Q45423719 | A three-dimensional model of the human immunodeficiency virus type 1 integration complex |
| Q46245422 | Activation/attenuation model for RNase H. A one-metal mechanism with second-metal inhibition. |
| Q34743380 | An amino acid in the central catalytic domain of three retroviral integrases that affects target site selection in nonviral DNA. |
| Q30500118 | Architecture of a full-length retroviral integrase monomer and dimer, revealed by small angle X-ray scattering and chemical cross-linking |
| Q38296937 | Assembly and catalysis of concerted two-end integration events by Moloney murine leukemia virus integrase |
| Q33237569 | Bacterial repetitive extragenic palindromic sequences are DNA targets for Insertion Sequence elements |
| Q35004628 | Binding modes of diketo-acid inhibitors of HIV-1 integrase: a comparative molecular dynamics simulation study |
| Q27740341 | Binding of different divalent cations to the active site of avian sarcoma virus integrase and their effects on enzymatic activity |
| Q37518408 | Biochemical and random mutagenesis analysis of the region carrying the catalytic E152 amino acid of HIV-1 integrase |
| Q44964528 | Biochemical requirements for inhibition of Connexin26-containing channels by natural and synthetic taurine analogs |
| Q41610600 | Brownian and essential dynamics studies of the HIV-1 integrase catalytic domain |
| Q27630838 | Catalytic center of an archaeal type 2 ribonuclease H as revealed by X-ray crystallographic and mutational analyses |
| Q77481353 | Changes in the mechanism of DNA integration in vitro induced by base substitutions in the HIV-1 U5 and U3 terminal sequences |
| Q34190096 | Comparison of multiple molecular dynamics trajectories calculated for the drug-resistant HIV-1 integrase T66I/M154I catalytic domain. |
| Q42119068 | Computational screening of inhibitors for HIV-1 integrase using a receptor based pharmacophore model |
| Q43853916 | Computer aided study of ligand binding with catalytic domain of Avian sarcoma virus integrase and its ligand binding loops |
| Q36145611 | Computer tools in the discovery of HIV-1 integrase inhibitors |
| Q33887759 | Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking |
| Q37007395 | Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function. |
| Q27627174 | Crystal structure of archaeal RNase HII: a homologue of human major RNase H |
| Q62673097 | Crystal structure of avian sarcoma virus integrase with bound essential cations |
| Q27625292 | Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding |
| Q33671188 | Crystal structures of catalytic core domains of retroviral integrases and role of divalent cations in enzymatic activity. |
| Q42648200 | Differential multimerization of Moloney murine leukemia virus integrase purified under nondenaturing conditions. |
| Q30175843 | Dissecting the role of the N-terminal domain of human immunodeficiency virus integrase by trans-complementation analysis |
| Q39580790 | Effects of mutations in residues near the active site of human immunodeficiency virus type 1 integrase on specific enzyme-substrate interactions |
| Q39952961 | Effects of varying the spacing within the D,D-35-E motif in the catalytic region of retroviral integrase |
| Q28379401 | Equivalent inhibition of half-site and full-site retroviral strand transfer reactions by structurally diverse compounds |
| Q27735010 | Flexibility in DNA recombination: structure of the lambda integrase catalytic core |
| Q45326555 | Functional analyses of mutants of the central core domain of an Avian Sarcoma/Leukemia Virus integrase |
| Q74473323 | Functional characterization of the Tn5 transposase by limited proteolysis |
| Q39551623 | Functional interactions of the HHCC domain of moloney murine leukemia virus integrase revealed by nonoverlapping complementation and zinc-dependent dimerization |
| Q45730026 | Functional oligomeric state of avian sarcoma virus integrase |
| Q36065855 | HIV DNA integration |
| Q30175416 | HIV integrase structure and function. |
| Q34247770 | HIV integrase, a brief overview from chemistry to therapeutics |
| Q41479059 | HIV integrase: a target for AIDS therapeutics |
| Q28367702 | HIV-1 integrase catalytic core: molecular dynamics and simulated fluorescence decays |
| Q34050694 | HIV-1 integrase inhibitors: past, present, and future |
| Q37034614 | HIV-1 integrase inhibitors: update and perspectives |
| Q28343322 | Human immunodeficiency virus type 1 integrase: arrangement of protein domains in active cDNA complexes |
| Q38307116 | Identification of HIV-1 integrase inhibitors via three-dimensional database searching using ASV and HIV-1 integrases as targets. |
| Q51213682 | Identification of RNase HII from psychrotrophic bacterium, Shewanella sp. SIB1 as a high-activity type RNase H. |
| Q52081212 | Identification of two catalytic residues in RAG1 that define a single active site within the RAG1/RAG2 protein complex. |
| Q45262143 | Identifying amino acid residues that contribute to the cellular-DNA binding site on retroviral integrase |
| Q34942626 | Impact of synchrotron radiation on macromolecular crystallography: a personal view |
| Q39642519 | Implication of a central cysteine residue and the HHCC domain of Moloney murine leukemia virus integrase protein in functional multimerization |
| Q35864113 | Inhibition of human immunodeficiency virus type 1 integrase by the Fab fragment of a specific monoclonal antibody suggests that different multimerization states are required for different enzymatic functions |
| Q39877349 | Intracellular expression of single-chain variable fragments to inhibit early stages of the viral life cycle by targeting human immunodeficiency virus type 1 integrase. |
| Q35577172 | Key determinants of target DNA recognition by retroviral intasomes |
| Q33782240 | Mapping viral DNA specificity to the central region of integrase by using functional human immunodeficiency virus type 1/visna virus chimeric proteins |
| Q37468745 | Molecular Interactions between HIV-1 integrase and the two viral DNA ends within the synaptic complex that mediates concerted integration |
| Q34997039 | Molecular and Genetic Determinants of Rous Sarcoma Virus Integrase for Concerted DNA Integration |
| Q34170581 | Molecular dynamics studies on the HIV-1 integrase catalytic domain |
| Q34063962 | Molecular genetics and target site specificity of retroviral integration |
| Q40868886 | Molecular mechanisms in retrovirus DNA integration |
| Q71032193 | Mu transpositional recombination: donor DNA cleavage and strand transfer in trans by the Mu transposase |
| Q45790359 | Multimerization determinants reside in both the catalytic core and C terminus of avian sarcoma virus integrase |
| Q45749105 | Multiple integrase functions are required to form the native structure of the human immunodeficiency virus type I intasome |
| Q76368269 | Mutational analyses of the core domain of Avian Leukemia and Sarcoma Viruses integrase: critical residues for concerted integration and multimerization |
| Q35210006 | Mutational analysis of RAG1 and RAG2 identifies three catalytic amino acids in RAG1 critical for both cleavage steps of V(D)J recombination |
| Q33359287 | Mutational analysis of highly conserved aspartate residues essential to the catalytic core of the piggyBac transposase |
| Q39578393 | Mutational scan of the human immunodeficiency virus type 2 integrase protein |
| Q79300526 | Mutations in the C‐terminal domain of ALSV (Avian Leukemia and Sarcoma Viruses) integrase alter the concerted DNA integration process in vitro |
| Q40178054 | Mutations in the catalytic core or the C-terminus of murine leukemia virus (MLV) integrase disrupt virion infectivity and exert diverse effects on reverse transcription |
| Q43837693 | N-Terminal domain of HTLV-I integrase. Complexation and conformational studies of the zinc finger |
| Q27660109 | ORF157 from the Archaeal Virus Acidianus Filamentous Virus 1 Defines a New Class of Nuclease |
| Q35208441 | Organization and dynamics of the Mu transpososome: recombination by communication between two active sites |
| Q35222265 | Patterns of sequence conservation at termini of long terminal repeat (LTR) retrotransposons and DNA transposons in the human genome: lessons from phage Mu. |
| Q37353786 | Piecing together the structure of retroviral integrase, an important target in AIDS therapy |
| Q54484307 | Processing of viral DNA ends channels the HIV-1 integration reaction to concerted integration. |
| Q30384774 | Protein crystallography for non-crystallographers, or how to get the best (but not more) from published macromolecular structures. |
| Q34288648 | RAG1 and RAG2 in V(D)J recombination and transposition |
| Q27628711 | Refined solution structure of the dimeric N-terminal HHCC domain of HIV-2 integrase |
| Q28596842 | Retroviral DNA Integration |
| Q35249277 | Retroviral DNA Transposition: Themes and Variations |
| Q36314249 | Retroviral DNA integration--mechanism and consequences |
| Q33787076 | Retroviral DNA integration. |
| Q34500837 | Retroviral DNA integration: reaction pathway and critical intermediates |
| Q34668065 | Retroviral Integrase Structure and DNA Recombination Mechanism |
| Q28073156 | Retroviral Integrase: Then and Now |
| Q39176798 | Retroviral integrase protein and intasome nucleoprotein complex structures |
| Q41029973 | Retroviral integrase, putting the pieces together |
| Q34387887 | Retroviral integrases and their cousins |
| Q79748685 | Retroviral integrases that are improved for processing but impaired for joining |
| Q33257614 | Revealing domain structure through linker-scanning analysis of the murine leukemia virus (MuLV) RNase H and MuLV and human immunodeficiency virus type 1 integrase proteins |
| Q35873097 | Reversion of a human immunodeficiency virus type 1 integrase mutant at a second site restores enzyme function and virus infectivity |
| Q45736590 | Role of DNA end distortion in catalysis by avian sarcoma virus integrase |
| Q73469975 | Similarities in the HIV-1 and ASV integrase active sites upon metal cofactor binding |
| Q30408688 | Soluble expression, purification and characterization of the full length IS2 Transposase |
| Q33887936 | Solution structure of the Mu end DNA-binding ibeta subdomain of phage Mu transposase: modular DNA recognition by two tethered domains. |
| Q27740763 | Solution structure of the N-terminal zinc binding domain of HIV-1 integrase |
| Q41701981 | Stereospecificity of reactions catalyzed by HIV-1 integrase |
| Q38356920 | Strategy to discriminate between high and low affinity bindings of human immunodeficiency virus, type 1 integrase to viral DNA. |
| Q27766079 | Structural basis for inactivating mutations and pH-dependent activity of avian sarcoma virus integrase |
| Q36806748 | Structural biology of retroviral DNA integration |
| Q42570699 | Structural biology: When four become one. |
| Q30175939 | Structural determinants of metal-induced conformational changes in HIV-1 integrase |
| Q27636829 | Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein |
| Q27749615 | Structure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitor |
| Q34141071 | Structure-based HIV-1 integrase inhibitor design: a future perspective |
| Q35882489 | Structure-based mutagenesis of the catalytic domain of human immunodeficiency virus type 1 integrase. |
| Q39580599 | Structure-based mutational analysis of the C-terminal DNA-binding domain of human immunodeficiency virus type 1 integrase: critical residues for protein oligomerization and DNA binding |
| Q35876147 | Subcellular localization of avian sarcoma virus and human immunodeficiency virus type 1 integrases |
| Q38993322 | Successes and challenges with retroviral enzymes |
| Q31164008 | Targeting Tn5 transposase identifies human immunodeficiency virus type 1 inhibitors |
| Q27733364 | The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of divalent cations |
| Q27734254 | The catalytic domain of human immunodeficiency virus integrase: ordered active site in the F185H mutant |
| Q71032186 | The interwoven architecture of the Mu transposase couples DNA synapsis to catalysis |
| Q36281117 | The molecular biology of HIV integrase |
| Q35610274 | The outs and ins of transposition: from mu to kangaroo |
| Q73878403 | The solution structure of the amino-terminal HHCC domain of HIV-2 integrase: a three-helix bundle stabilized by zinc |
| Q27617962 | The three-dimensional structure of a Tn5 transposase-related protein determined to 2.9-A resolution |
| Q27764898 | Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium |
| Q36486586 | Tn552 transposase catalyzes concerted strand transfer in vitro |
| Q33888644 | Transposase makes critical contacts with, and is stimulated by, single-stranded DNA at the P element termini in vitro |
| Q41011364 | Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system |
| Q37485954 | True reversal of Mu integration |
| Q35830443 | V(D)J recombination: how to tame a transposase |
| Q35922636 | Zinc folds the N-terminal domain of HIV-1 integrase, promotes multimerization, and enhances catalytic activity |
| Q30047434 | [28] Phase determination from multiwavelength anomalous diffraction measurements |
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