A ligand-gated, hinged loop rearrangement opens a channel to a buried artificial protein cavity

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A ligand-gated, hinged loop rearrangement opens a channel to a buried artificial protein cavity is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1049596700
P356DOI10.1038/NSB0796-626
P698PubMed publication ID8673607
P5875ResearchGate publication ID14527350

P2093author name stringD B Goodin
D E McRee
M M Fitzgerald
R A Musah
P2860cites workApplication of a Theory of Enzyme Specificity to Protein SynthesisQ24620284
A cavity-containing mutant of T4 lysozyme is stabilized by buried benzeneQ27643869
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The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1Q27731226
Small molecule binding to an artificially created cavity at the active site of cytochrome c peroxidaseQ27731261
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Crystallographic R factor refinement by molecular dynamicsQ27860942
Response of a protein structure to cavity-creating mutations and its relation to the hydrophobic effectQ28292427
Solvent-accessible surfaces of proteins and nucleic acidsQ29614464
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Amino acid preferences for specific locations at the ends of alpha helicesQ29618508
Rate theories and puzzles of hemeprotein kineticsQ30407135
Identification by ENDOR of Trp191 as the free-radical site in cytochrome c peroxidase compound ES.Q34042682
The role of aspartate-235 in the binding of cations to an artificial cavity at the radical site of cytochrome c peroxidaseQ36279350
Dynamics of the flexible loop of triosephosphate isomerase: the loop motion is not ligand gatedQ41674035
Segmental movement: definition of the structural requirements for loop closure in catalysis by triosephosphate isomeraseQ42603338
Solvent viscosity and protein dynamicsQ42671854
Detection of an oxyferryl porphyrin pi-cation-radical intermediate in the reaction between hydrogen peroxide and a mutant yeast cytochrome c peroxidase. Evidence for tryptophan-191 involvement in the radical site of compound I.Q43606566
Characterization of a folding intermediate of apoplastocyanin trapped by proline isomerizationQ44346116
Structural and evolutionary relationships between retroviral and eukaryotic aspartic proteinasesQ44626059
Crystal structure of nitric oxide inhibited cytochrome c peroxidaseQ46547057
Comprehensive explanation of the anomalous EPR spectra of wild-type and mutant cytochrome c peroxidase compound ES.Q52397232
Dynamics of a flexible loop in dihydrofolate reductase from Escherichia coli and its implication for catalysis.Q54642715
Functional role of a mobile loop of Escherichia coli dihydrofolate reductase in transition-state stabilizationQ68026082
P433issue7
P304page(s)626-31
P577publication date1996-07-01
P1433published inNature structural biologyQ26842658
P1476titleA ligand-gated, hinged loop rearrangement opens a channel to a buried artificial protein cavity
P478volume3

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