Thermodynamic analysis of halide binding to haloalkane dehalogenase suggests the occurrence of large conformational changes

scientific article published on February 1999

Thermodynamic analysis of halide binding to haloalkane dehalogenase suggests the occurrence of large conformational changes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1110/PS.8.2.355
P932PMC publication ID2144270
P698PubMed publication ID10048328
P5875ResearchGate publication ID13242631

P2093author name stringFloris R
Janssen DB
Krooshof GH
Tepper AW
P2860cites workRefined X-ray structures of haloalkane dehalogenase at pH 6.2 and pH 8.2 and implications for the reaction mechanismQ27731980
Crystallographic analysis of the catalytic mechanism of haloalkane dehalogenaseQ27732188
A ligand-gated, hinged loop rearrangement opens a channel to a buried artificial protein cavityQ27732870
Kinetic characterization and X-ray structure of a mutant of haloalkane dehalogenase with higher catalytic activity and modified substrate rangeQ27733700
Kinetic analysis and X-ray structure of haloalkane dehalogenase with a modified halide-binding siteQ27765748
GEPASI: a software package for modelling the dynamics, steady states and control of biochemical and other systemsQ34348589
Two conformational states of Candida rugosa lipaseQ36278235
Histidine 289 is essential for hydrolysis of the alkyl-enzyme intermediate of haloalkane dehalogenaseQ38295626
Rapid quench kinetic analysis of polymerases, adenosinetriphosphatases, and enzyme intermediatesQ40550874
Characterization of a folding intermediate of apoplastocyanin trapped by proline isomerizationQ44346116
Site-directed mutagenesis and oxygen isotope incorporation studies of the nucleophilic aspartate of haloalkane dehalogenaseQ48085044
Specificity and kinetics of haloalkane dehalogenase.Q52303142
Kinetics of halide release of haloalkane dehalogenase: evidence for a slow conformational change.Q54588772
Construction of an expression and site-directed mutagenesis system of haloalkane dehalogenase in Escherichia coli.Q54650466
Effect of prolyl isomerase on the folding reactions of staphylococcal nucleaseQ73940344
Raising water to new heightsQ81220497
P433issue2
P304page(s)355-360
P577publication date1999-02-01
P1433published inProtein ScienceQ7251445
P1476titleThermodynamic analysis of halide binding to haloalkane dehalogenase suggests the occurrence of large conformational changes
P478volume8

Reverse relations

cites work (P2860)
Q62274595Conformational changes allow processing of bulky substrates by a haloalkane dehalogenase with a small and buried active site
Q64980883Dehalogenases: From Improved Performance to Potential Microbial Dehalogenation Applications.
Q36639249Functionally relevant motions of haloalkane dehalogenases occur in the specificity-modulating cap domains
Q43947032Molecular dynamics simulations as a tool for improving protein stability

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