Automated protein model building combined with iterative structure refinement

scientific article (publication date: May 1999)

Automated protein model building combined with iterative structure refinement is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1037336361
P356DOI10.1038/8263
P3181OpenCitations bibliographic resource ID631520
P698PubMed publication ID10331874
P5875ResearchGate publication ID12966602

P50authorAnastassis PerrakisQ28320511
Richard J MorrisQ38319860
P2093author name stringV S Lamzin
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectautomationQ184199
protein structureQ735188
P304page(s)458-63
P577publication date1999-05-01
P1433published inNature structural biologyQ26842658
P1476titleAutomated protein model building combined with iterative structure refinement
P478volume6

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cites work (P2860)
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Q27644045Apo and Calcium-bound Crystal Structures of Alpha-11 Giardin, an Unusual Annexin from Giardia lamblia
Q27660139Apo and ligand-bound structures of ModA from the archaeonMethanosarcina acetivorans
Q27668136Apo raver1 structure reveals distinct RRM domain orientations
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Q27639213Archaeal Sm proteins form heptameric and hexameric complexes: crystal structures of the Sm1 and Sm2 proteins from the hyperthermophile Archaeoglobus fulgidus
Q27649521Archaeal protoglobin structure indicates new ligand diffusion paths and modulation of haem-reactivity
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Q27644735Atomic resolution insight into host cell recognition by Toxoplasma gondii
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Q27639970Atomic structure of Mycobacterium tuberculosis CYP121 to 1.06 A reveals novel features of cytochrome P450
Q27678807Atomic structure of the nuclear pore complex targeting domain of a nup116 homologue from the yeast, Candida glabrata
Q27648915Atomic-resolution crystal structure of the antiviral lectin scytovirin
Q27860936Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7
Q27861082Automated main-chain model building by template matching and iterative fragment extension
Q33253602Automated protein-ligand crystallography for structure-based drug design
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Q56877796Automatic Solution of Heavy-Atom Substructures
Q41940007Automating crystallographic structure solution and refinement of protein-ligand complexes.
Q27640041Autotracing of Escherichia coli acetate CoA-transferase alpha-subunit structure using 3.4 A MAD and 1.9 A native data
Q92797023B1 oligomerization regulates PML nuclear body biogenesis and leukemogenesis
Q27860570BALBES: a molecular-replacement pipeline
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Q27649557Bacterial polysaccharide co-polymerases share a common framework for control of polymer length
Q27677799Bacteriophage P23-77 Capsid Protein Structures Reveal the Archetype of an Ancient Branch from a Major Virus Lineage
Q24301800Bardet-Biedl syndrome-associated small GTPase ARL6 (BBS3) functions at or near the ciliary gate and modulates Wnt signaling
Q27675927Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family
Q27649855Bifunctional NMN Adenylyltransferase/ADP-Ribose Pyrophosphatase: Structure and Function in Bacterial NAD Metabolism
Q31030689Binding of different monosaccharides by lectin PA-IIL from Pseudomonas aeruginosa: thermodynamics data correlated with X-ray structures
Q27642001Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change
Q24307993Binding of the PX domain of p47(phox) to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interaction
Q28829782Biocatalytic Asymmetric Alkene Reduction: Crystal Structure and Characterization of a Double Bond Reductase from Nicotiana tabacum
Q27649089Biochemical and Structural Characterization of a Novel Family of Cystathionine β-Synthase Domain Proteins Fused to a Zn Ribbon-Like Domain
Q27680563Biochemical and Structural Studies of Conserved Maf Proteins Revealed Nucleotide Pyrophosphatases with a Preference for Modified Nucleotides
Q27675880Biochemical and Structural Studies of Uncharacterized Protein PA0743 from Pseudomonas aeruginosa Revealed NAD+-dependent L-Serine Dehydrogenase
Q27677244Biochemical and Structural Studies of the Mycobacterium tuberculosis O6-Methylguanine Methyltransferase and Mutated Variants
Q38313265Biochemical and structural analysis of Helix pomatia agglutinin. A hexameric lectin with a novel fold
Q28601088Biochemical and structural characterization of polyphosphate kinase 2 from the intracellular pathogen Francisella tularensis
Q24315733Biochemical and structural characterization of the gem GTPase
Q24621823Biochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesis
Q28144948Biological function made crystal clear - annotation of hypothetical proteins via structural genomics
Q30411062Biophysical analysis of the putative acetyltransferase SACOL2570 from methicillin-resistant Staphylococcus aureus
Q27641732Biosynthesis of isoprenoids: Crystal structure of 4-diphosphocytidyl-2C-methyl-D-erythritol kinase
Q27648724Bis-methionyl Coordination in the Crystal Structure of the Heme-binding Domain of the Streptococcal Cell Surface Protein Shp
Q34597298Bispecific abs against modified protein and DNA with oxidized lipids
Q27677012Bivalent Carbohydrate Binding Is Required for Biological Activity of Clitocybe nebularis Lectin (CNL), the N,N'-Diacetyllactosediamine (GalNAc 1-4GlcNAc, LacdiNAc)-specific Lectin from Basidiomycete C. nebularis
Q27654107Blood Group Antigen Recognition by a Solute-Binding Protein from a Serotype 3 Strain of Streptococcus pneumoniae
Q31061712Blood group antigen recognition by a Streptococcus pneumoniae virulence factor
Q27657889Bothnia dystrophy is caused by domino-like rearrangements in cellular retinaldehyde-binding protein mutant R234W
Q27664646Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral Cap-Dependent Transcription
Q27677974CC2D1A Is a Regulator of ESCRT-III CHMP4B
Q24337746CLASP2 Has Two Distinct TOG Domains That Contribute Differently to Microtubule Dynamics
Q36668865Can I solve my structure by SAD phasing? Anomalous signal in SAD phasing.
Q27641763Candida tropicalis expresses two mitochondrial 2-enoyl thioester reductases that are able to form both homodimers and heterodimers
Q36342243Cas5d processes pre-crRNA and is a member of a larger family of CRISPR RNA endonucleases
Q55041982Catalytic mechanism and structure of viral flavin-dependent thymidylate synthase ThyX.
Q36959595Central base pair flipping and discrimination by PspGI.
Q46140634Challenges of sulfur SAD phasing as a routine method in macromolecular crystallography
Q27663730Channeling and conformational changes in the heterotetrameric sarcosine oxidase from Corynebacterium sp. U-96
Q24671918Channelling and formation of 'active' formaldehyde in dimethylglycine oxidase
Q27674716Characterization of Staphylococcus aureus EssB, an integral membrane component of the Type VII secretion system: atomic resolution crystal structure of the cytoplasmic segment
Q27670794Characterization of the Deoxynucleotide Triphosphate Triphosphohydrolase (dNTPase) Activity of the EF1143 Protein from Enterococcus faecalis and Crystal Structure of the Activator-Substrate Complex
Q27664981Chimeric avidin shows stability against harsh chemical conditions--biochemical analysis and 3D structure
Q27649863Cholix toxin, a novel ADP-ribosylating factor from Vibrio cholerae
Q51102354Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity.
Q27639341Class I tyrosyl-tRNA synthetase has a class II mode of cognate tRNA recognition
Q27675533Classification of a Haemophilus influenzae ABC Transporter HI1470/71 through Its Cognate Molybdate Periplasmic Binding Protein, MolA
Q24617142Cloning, Baeyer-Villiger biooxidations, and structures of the camphor pathway 2-oxo-Δ(3)-4,5,5-trimethylcyclopentenylacetyl-coenzyme A monooxygenase of Pseudomonas putida ATCC 17453
Q46754157Cloning, expression, characterisation and three-dimensional structure determination of Caenorhabditis elegans spermidine synthase
Q42110608Coenzyme- and His-tag-induced crystallization of octopine dehydrogenase
Q28550279Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases
Q30549619Comparative proteomics identifies the cell-associated lethality of M. tuberculosis RelBE-like toxin-antitoxin complexes
Q27681434Comparative structural and functional analysis of orthomyxovirus polymerase cap-snatching domains
Q64124737Comparison of Alicyclobacillus acidocaldarius o-Succinylbenzoate Synthase to Its Promiscuous N-Succinylamino Acid Racemase/ o-Succinylbenzoate Synthase Relatives
Q24621015Comparison of apo- and heme-bound crystal structures of a truncated human heme oxygenase-2
Q27678088Comparison of the structural changes in two cellobiohydrolases, CcCel6A and CcCel6C, from Coprinopsis cinerea--a tweezer-like motion in the structure of CcCel6C
Q27652276Completing the family portrait of the anti-apoptotic Bcl-2 proteins: crystal structure of human Bfl-1 in complex with Bim
Q27651059Complexes of the copper-containing amine oxidase fromArthrobacter globiformiswith the inhibitors benzylhydrazine and tranylcypromine
Q27679889Conformational Plasticity and Ligand Binding of Bacterial Monoacylglycerol Lipase
Q89965793Conformational Plasticity of HLA-B27 Molecules Correlates Inversely With Efficiency of Negative T Cell Selection
Q40362650Conformational dimorphism of self-peptides and molecular mimicry in a disease-associated HLA-B27 subtype
Q27682005Conformational flexibility in the catalytic triad revealed by the high-resolution crystal structure ofStreptomyces erythraeustrypsin in an unliganded state
Q27650458Conformational gating of dimannose binding to the antiviral protein cyanovirin revealed from the crystal structure at 1.35 Å resolution
Q40513209Conotoxin αD-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors
Q24541480Consensus-derived structural determinants of the ankyrin repeat motif
Q27654522Contraction of the disordered loop located within C-terminal domain of the transcriptional regulator HlyIIR causes its structural rearrangement
Q34188142Contribution of single tryptophan residues to the fluorescence and stability of ribonuclease Sa
Q27668148Contribution of the 80s loop of HIV-1 protease to the multidrug-resistance mechanism: crystallographic study of MDR769 HIV-1 protease variants
Q27681587CorA Is a Copper Repressible Surface-Associated Copper(I)-Binding Protein Produced in Methylomicrobium album BG8
Q27658961Coupled chaperone action in folding and assembly of hexadecameric Rubisco
Q33621760Crystal Structural and Functional Analysis of the Putative Dipeptidase from Pyrococcus horikoshii OT3
Q27668109Crystal Structure Analysis Reveals Functional Flexibility in the Selenocysteine-Specific tRNA from Mouse
Q27657661Crystal Structure and Catalytic Mechanism of 4-Methylmuconolactone Methylisomerase
Q27681551Crystal Structure and Characterization of the Glycoside Hydrolase Family 62 α-l-Arabinofuranosidase fromStreptomyces coelicolor
Q27677366Crystal Structure and Mode of Helicase Binding of the C-Terminal Domain of Primase from Helicobacter pylori
Q27677240Crystal Structure and Site-Directed Mutagenesis Analyses of Haloalkane Dehalogenase LinB from Sphingobium sp. Strain MI1205
Q27666159Crystal Structure and Size-Dependent Neutralization Properties of HK20, a Human Monoclonal Antibody Binding to the Highly Conserved Heptad Repeat 1 of gp41
Q47960807Crystal Structure and Substrate Specificity Modification of Acetyl Xylan Esterase from Aspergillus luchuensis
Q27681209Crystal Structure of Arabidopsis Cyclophilin38 Reveals a Previously Uncharacterized Immunophilin Fold and a Possible Autoinhibitory Mechanism
Q27651618Crystal Structure of Botulinum Neurotoxin Type A in Complex with the Cell Surface Co-Receptor GT1b—Insight into the Toxin–Neuron Interaction
Q27678893Crystal Structure of ChrR—A Quinone Reductase with the Capacity to Reduce Chromate
Q27678177Crystal Structure of Diedel, a Marker of the Immune Response of Drosophila melanogaster
Q27640737Crystal Structure of Enterococcus faecalis SlyA-like Transcriptional Factor
Q27651883Crystal Structure of Escherichia coli Rnk, a New RNA Polymerase-Interacting Protein
Q27657880Crystal Structure of Family 14 Polysaccharide Lyase with pH-dependent Modes of Action
Q27661326Crystal Structure of Full-length Mycobacterium tuberculosis H37Rv Glycogen Branching Enzyme
Q27653650Crystal Structure of Glycoside Hydrolase Family 55  -1,3-Glucanase from the Basidiomycete Phanerochaete chrysosporium
Q27652078Crystal Structure of Human Plasma Platelet-activating Factor Acetylhydrolase: STRUCTURAL IMPLICATION TO LIPOPROTEIN BINDING AND CATALYSIS
Q27658379Crystal Structure of Prolyl 4-Hydroxylase from Bacillus anthracis
Q27642296Crystal Structure of Putidaredoxin, the [2Fe–2S] Component of the P450cam Monooxygenase System from Pseudomonas putida
Q27675109Crystal Structure of Reduced MsAcg, a Putative Nitroreductase from Mycobacterium smegmatis and a Close Homologue of Mycobacterium tuberculosis Acg
Q27642191Crystal Structure of Trimestatin, a Disintegrin Containing a Cell Adhesion Recognition Motif RGD
Q27655548Crystal Structure of a Class XIB Phospholipase A2 (PLA2): RICE (ORYZA SATIVA) ISOFORM-2 PLA2 AND AN OCTANOATE COMPLEX
Q51408849Crystal Structure of a Complex of the Intracellular Domain of Interferon λ Receptor 1 (IFNLR1) and the FERM/SH2 Domains of Human JAK1.
Q27650101Crystal Structure of a Functional Dimer of the PhoQ Sensor Domain
Q27657439Crystal Structure of a Mucus-binding Protein Repeat Reveals an Unexpected Functional Immunoglobulin Binding Activity
Q27670452Crystal Structure of a Zinc-dependent D-Serine Dehydratase from Chicken Kidney
Q27676682Crystal Structure of an Uncommon Cellulosome-Related Protein Module from Ruminococcus flavefaciens That Resembles Papain-Like Cysteine Peptidases
Q27660172Crystal Structure of the Botulinum Neurotoxin Type G Binding Domain: Insight into Cell Surface Binding
Q90661738Crystal Structure of the Catalytic and Cytochrome b Domains in a Eukaryotic Pyrroloquinoline Quinone-Dependent Dehydrogenase
Q27656921Crystal Structure of the Frizzled-Like Cysteine-Rich Domain of the Receptor Tyrosine Kinase MuSK
Q27662541Crystal Structure of the GalNAc/Gal-Specific Agglutinin from the Phytopathogenic Ascomycete Sclerotinia sclerotiorum Reveals Novel Adaptation of a β-Trefoil Domain
Q27679392Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex
Q27659681Crystal Structure of the Narrow-Spectrum OXA-46 Class D  -Lactamase: Relationship between Active-Site Lysine Carbamylation and Inhibition by Polycarboxylates
Q27661588Crystal Structure of the Neutralizing Llama VHH D7 and Its Mode of HIV-1 gp120 Interaction
Q27659184Crystal Structure of the Peptidase Domain of Streptococcus ComA, a Bifunctional ATP-binding Cassette Transporter Involved in the Quorum-sensing Pathway
Q27651384Crystal Structure of the Thermus thermophilus 16 S rRNA Methyltransferase RsmC in Complex with Cofactor and Substrate Guanosine
Q27648859Crystal Structure of the Transcriptional Regulator AcrR from Escherichia coli
Q27647080Crystal Structure of the Transcriptional Regulator CmeR from Campylobacter jejuni
Q27667330Crystal Structure of the Vibrio cholerae Colonization Factor TcpF and Identification of a Functional Immunogenic Site
Q27648832Crystal Structure of the interleukin-15.interleukin-15 receptor alpha complex: insights into trans and cis presentation
Q27663873Crystal Structure-Based Selective Targeting of the Pyridoxal 5′-Phosphate Dependent Enzyme Kynurenine Aminotransferase II for Cognitive Enhancement
Q27661614Crystal Structures of Aspergillus japonicus Fructosyltransferase Complex with Donor/Acceptor Substrates Reveal Complete Subsites in the Active Site for Catalysis
Q27670903Crystal Structures of Bacterial Peptidoglycan Amidase AmpD and an Unprecedented Activation Mechanism
Q27651548Crystal Structures of C4-Dicarboxylate Ligand Complexes with Sensor Domains of Histidine Kinases DcuS and DctB
Q27653132Crystal Structures of Cytochrome P450 105P1 from Streptomyces avermitilis: Conformational Flexibility and Histidine Ligation State
Q27667369Crystal Structures of Human TBC1D1 and TBC1D4 (AS160) RabGTPase-activating Protein (RabGAP) Domains Reveal Critical Elements for GLUT4 Translocation
Q27664178Crystal Structures of Phosphoketolase: THIAMINE DIPHOSPHATE-DEPENDENT DEHYDRATION MECHANISM
Q27655490Crystal Structures of Two Archaeal 8-Oxoguanine DNA Glycosylases Provide Structural Insight into Guanine/8-Oxoguanine Distinction
Q27652786Crystal Structures of Two Coronavirus ADP-Ribose-1''-Monophosphatases and Their Complexes with ADP-Ribose: a Systematic Structural Analysis of the Viral ADRP Domain
Q27671848Crystal Structures of a CTX  pIII Domain Unbound and in Complex with a Vibrio cholerae TolA Domain Reveal Novel Interaction Interfaces
Q27676765Crystal Structures of a Glycoside Hydrolase Family 20 Lacto-N-biosidase from Bifidobacterium bifidum
Q27648948Crystal Structures of the Luciferase and Green Fluorescent Protein from Renilla reniformis
Q27667783Crystal Structures of the Transcriptional Repressor RolR Reveals a Novel Recognition Mechanism between Inducer and Regulator
Q27641504Crystal complexes of a predicted S-adenosylmethionine-dependent methyltransferase reveal a typical AdoMet binding domain and a substrate recognition domain
Q27684256Crystal structure analysis of a fatty acid double-bond hydratase from Lactobacillus acidophilus
Q27676488Crystal structure analysis of a recombinant predicted acetamidase/formamidase from the thermophile Thermoanaerobacter tengcongensis
Q38330458Crystal structure and DNA-binding analysis of RecO from Deinococcus radiodurans.
Q27629468Crystal structure and deletion analysis show that the accessory subunit of mammalian DNA polymerase gamma, Pol gamma B, functions as a homodimer
Q31051866Crystal structure and desulfurization mechanism of 2'-hydroxybiphenyl-2-sulfinic acid desulfinase
Q24531093Crystal structure and electron transfer kinetics of CueO, a multicopper oxidase required for copper homeostasis in Escherichia coli
Q34366536Crystal structure and functional analysis of DEAD-box protein Dhh1p
Q27641912Crystal structure and functional analysis of Drosophila Wind, a protein-disulfide isomerase-related protein
Q44852703Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe
Q27694818Crystal structure and its bearing towards an understanding of key biological functions of EpCAM
Q27666525Crystal structure and mode of action of a class V chitinase from Nicotiana tabacum
Q27658298Crystal structure and molecular modeling study of N-carbamoylsarcosine amidase Ta0454 from Thermoplasma acidophilum
Q27647394Crystal structure and putative function of small Toprim domain-containing protein from Bacillus stearothermophilus
Q27642249Crystal structure and snapshots along the reaction pathway of a family 51 -L-arabinofuranosidase
Q27643762Crystal structure and solution characterization of the activation domain of human methionine synthase
Q36458279Crystal structure of 3-hydroxyanthranilic acid 3,4-dioxygenase from Saccharomyces cerevisiae: a special subgroup of the type III extradiol dioxygenases
Q27654344Crystal structure of AFV1-102, a protein from theAcidianus Filamentous Virus 1
Q21245135Crystal structure of AFV3-109, a highly conserved protein from crenarchaeal viruses
Q43020228Crystal structure of AmyA lacks acidic surface and provide insights into protein stability at poly-extreme condition
Q33263320Crystal structure of Bacillus cereus HlyIIR, a transcriptional regulator of the gene for pore-forming toxin hemolysin II.
Q37471239Crystal structure of Bacillus subtilis YckF: structural and functional evolution.
Q27648675Crystal structure of Cel44A, a glycoside hydrolase family 44 endoglucanase from Clostridium thermocellum
Q27641084Crystal structure of Escherichia coli sigmaE with the cytoplasmic domain of its anti-sigma RseA
Q24598272Crystal structure of FadR, a fatty acid-responsive transcription factor with a novel acyl coenzyme A-binding fold
Q27666850Crystal structure of HP0721, a novel secreted protein from Helicobacter pylori
Q24653746Crystal structure of Homo sapiens kynureninase
Q24297467Crystal structure of Homo sapiens protein LOC79017
Q34489087Crystal structure of HugZ, a novel heme oxygenase from Helicobacter pylori
Q27635292Crystal structure of Klebsiella aerogenes UreE, a nickel-binding metallochaperone for urease activation
Q27689315Crystal structure of L-sorbose dehydrogenase, a pyrroloquinoline quinone-dependent enzyme with homodimeric assembly, from Ketogulonicigenium vulgare
Q24630452Crystal structure of Leishmania major oligopeptidase B gives insight into the enzymatic properties of a trypanosomatid virulence factor
Q27642975Crystal structure of MO25 alpha in complex with the C terminus of the pseudo kinase STE20-related adaptor
Q27640988Crystal structure of Mg2+- and Ca2+-bound Gla domain of factor IX complexed with binding protein
Q34166584Crystal structure of Mil (Mth680): internal duplication and similarity between the Imp4/Brix domain and the anticodon-binding domain of class IIa aminoacyl-tRNA synthetases
Q21135758Crystal structure of Spy0129, a Streptococcus pyogenes class B sortase involved in pilus assembly
Q46896191Crystal structure of Staphylococcus aureus tRNA adenosine deaminase TadA in complex with RNA.
Q27634505Crystal structure of Streptococcus mutans pyrophosphatase: a new fold for an old mechanism
Q27628944Crystal structure of Streptococcus pneumoniae N-acetylglucosamine-1-phosphate uridyltransferase bound to acetyl-coenzyme A reveals a novel active site architecture
Q27650417Crystal structure of Tflp: a ferredoxin-like metallo-beta-lactamase superfamily protein from Thermoanaerobacter tengcongensis
Q27642919Crystal structure of Thermotoga maritima alpha-L-fucosidase. Insights into the catalytic mechanism and the molecular basis for fucosidosis
Q27628727Crystal structure of Trbp111: a structure-specific tRNA-binding protein
Q27622559Crystal structure of YbaK protein from Haemophilus influenzae (HI1434) at 1.8 A resolution: functional implications
Q27636863Crystal structure of YecO from Haemophilus influenzae (HI0319) reveals a methyltransferase fold and a bound S-adenosylhomocysteine
Q41457535Crystal structure of Yersinia enterocolitica type III secretion chaperone SycT.
Q24628795Crystal structure of a 117 kDa glucansucrase fragment provides insight into evolution and product specificity of GH70 enzymes
Q24561935Crystal structure of a Baeyer-Villiger monooxygenase
Q27627081Crystal structure of a D-aminopeptidase from Ochrobactrum anthropi, a new member of the 'penicillin-recognizing enzyme' family
Q27651380Crystal structure of a UDP-glucose-specific glycosyltransferase from a Mycobacterium species
Q27635332Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication
Q27646035Crystal structure of a bacterial albumin-binding domain at 1.4 A resolution
Q27640698Crystal structure of a bacterial endospore coat component. A laccase with enhanced thermostability properties
Q29616590Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters
Q42676269Crystal structure of a bacterial type IB DNA topoisomerase reveals a preassembled active site in the absence of DNA.
Q24321428Crystal structure of a dimeric oxidized form of human peroxiredoxin 5
Q45064158Crystal structure of a dodecameric tetrahedral-shaped aminopeptidase
Q27648731Crystal structure of a family I.3 lipase from Pseudomonas sp. MIS38 in a closed conformation
Q57898162Crystal structure of a feruloyl esterase belonging to the tannase family: A disulfide bond near a catalytic triad
Q27659737Crystal structure of a glycoside hydrolase family 6 enzyme, CcCel6C, a cellulase constitutively produced by Coprinopsis cinerea
Q27643947Crystal structure of a histidine kinase sensor domain with similarity to periplasmic binding proteins
Q37621873Crystal structure of a human CD3-epsilon/delta dimer in complex with a UCHT1 single-chain antibody fragment.
Q24539028Crystal structure of a human aminoacyl-tRNA synthetase cytokine
Q27642420Crystal structure of a hypothetical protein, TT1725, from Thermus thermophilus HB8 at 1.7 A resolution
Q43067615Crystal structure of a lipoxygenase from Cyanothece sp. may reveal novel features for substrate acquisition
Q27639989Crystal structure of a major secreted protein of Mycobacterium tuberculosis-MPT63 at 1.5-Å resolution
Q27666455Crystal structure of a novel non-Pfam protein PF2046 solved using low resolution B-factor sharpening and multi-crystal averaging methods
Q37471206Crystal structure of a novel shikimate dehydrogenase from Haemophilus influenzae.
Q27667347Crystal structure of a phenol-coupling P450 monooxygenase involved in teicoplanin biosynthesis
Q27639602Crystal structure of a prostate kallikrein isolated from stallion seminal plasma: a homologue of human PSA
Q35546797Crystal structure of a putative HTH-type transcriptional regulator yxaF from Bacillus subtilis.
Q27679429Crystal structure of a putative aspartic proteinase domain of theMycobacterium tuberculosiscell surface antigen PE_PGRS16
Q27677386Crystal structure of a putative isochorismatase hydrolase from Oleispira antarctica
Q27680491Crystal structure of a putative quorum sensing-regulated protein (PA3611) from the Pseudomonas-specific DUF4146 family
Q27668091Crystal structure of a putative transcriptional regulator SCO0520 from Streptomyces coelicolor A3(2) reveals an unusual dimer among TetR family proteins
Q28273696Crystal structure of a ternary complex of DnrK, a methyltransferase in daunorubicin biosynthesis, with bound products
Q27639911Crystal structure of a thermostable lipase from Bacillus stearothermophilus P1
Q27646378Crystal structure of a transcriptional regulator TM1030 from Thermotoga maritima solved by an unusual MAD experiment
Q27640340Crystal structure of a trimeric form of dephosphocoenzyme A kinase from Escherichia coli
Q27663517Crystal structure of a truncated urease accessory protein UreF from Helicobacter pylori
Q34419574Crystal structure of acetylcholine-binding protein from Bulinus truncatus reveals the conserved structural scaffold and sites of variation in nicotinic acetylcholine receptors.
Q27641730Crystal structure of aclacinomycin methylesterase with bound product analogues: implications for anthracycline recognition and mechanism
Q27648480Crystal structure of activin receptor type IIB kinase domain from human at 2.0 Å resolution
Q27628998Crystal structure of alkaline phosphatase from human placenta at 1.8 A resolution. Implication for a substrate specificity
Q27648249Crystal structure of aminopeptidase N from human pathogen Neisseria meningitidis
Q27641811Crystal structure of an ADP-dependent glucokinase from Pyrococcus furiosus: implications for a sugar-induced conformational change in ADP-dependent kinase
Q27641913Crystal structure of an archaeal class I aldolase and the evolution of (betaalpha)8 barrel proteins
Q27660234Crystal structure of an eIF4G-like protein fromDanio rerio
Q54433470Crystal structure of an unusual thioredoxin protein with a zinc finger domain.
Q27648905Crystal structure of anapoform ofShigella flexneriArsH protein with an NADPH-dependent FMN reductase activity
Q30163863Crystal structure of archaeal ribonuclease P protein Ph1771p from Pyrococcus horikoshii OT3: an archaeal homolog of eukaryotic ribonuclease P protein Rpp29
Q36973191Crystal structure of botulinum neurotoxin type G light chain: serotype divergence in substrate recognition
Q27653847Crystal structure of bovine 3-hydroxyanthranilate 3,4-dioxygenase
Q27648745Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine analogue
Q24562017Crystal structure of elongation factor P from Thermus thermophilus HB8
Q38319400Crystal structure of enteric adenovirus serotype 41 short fiber head
Q27641149Crystal structure of fungal lectin: six-bladed beta-propeller fold and novel fucose recognition mode for Aleuria aurantia lectin
Q30351378Crystal structure of glucooligosaccharide oxidase from Acremonium strictum: a novel flavinylation of 6-S-cysteinyl, 8alpha-N1-histidyl FAD.
Q37008173Crystal structure of glutamate-1-semialdehyde-2,1-aminomutase from Arabidopsis thaliana
Q58612169Crystal structure of heme A synthase from
Q34505592Crystal structure of heparinase II from Pedobacter heparinus and its complex with a disaccharide product
Q27664996Crystal structure of hexokinase KlHxk1 of Kluyveromyces lactis: a molecular basis for understanding the control of yeast hexokinase functions via covalent modification and oligomerization
Q27670989Crystal structure of human MTH1 and the 8-oxo-dGMP product complex
Q24630615Crystal structure of human alpha-tocopherol transfer protein bound to its ligand: implications for ataxia with vitamin E deficiency
Q24683471Crystal structure of human cyclin K, a positive regulator of cyclin-dependent kinase 9
Q27644341Crystal structure of human cytosolic 5'-nucleotidase II: insights into allosteric regulation and substrate recognition
Q24311982Crystal structure of human diphosphoinositol phosphatase 1
Q34586219Crystal structure of human inosine triphosphatase. Substrate binding and implication of the inosine triphosphatase deficiency mutation P32T.
Q27649208Crystal structure of human kynurenine aminotransferase II, a drug target for the treatment of schizophrenia
Q24299598Crystal structure of human otubain 2.
Q27642396Crystal structure of human pirin: an iron-binding nuclear protein and transcription cofactor
Q24297054Crystal structure of human riboflavin kinase reveals a beta barrel fold and a novel active site arch
Q34405959Crystal structure of human vacuolar protein sorting protein 29 reveals a phosphodiesterase/nuclease-like fold and two protein-protein interaction sites.
Q36458420Crystal structure of hypothetical protein TTHB192 from Thermus thermophilus HB8 reveals a new protein family with an RNA recognition motif-like domain
Q30437663Crystal structure of hypothetical protein YfiH from Shigella flexneri at 2 A resolution
Q24657898Crystal structure of iodotyrosine deiodinase, a novel flavoprotein responsible for iodide salvage in thyroid glands
Q27654519Crystal structure of isoflurane bound to integrin LFA-1 supports a unified mechanism of volatile anesthetic action in the immune and central nervous systems
Q27630979Crystal structure of isopentenyl diphosphate:dimethylallyl diphosphate isomerase
Q27670797Crystal structure of menin reveals binding site for mixed lineage leukemia (MLL) protein
Q27676541Crystal structure of microsomal prostaglandin E2 synthase provides insight into diversity in the MAPEG superfamily
Q47251372Crystal structure of native β-N-acetylhexosaminidase isolated from Aspergillus oryzae sheds light onto its substrate specificity, high stability, and regulation by propeptide
Q34697647Crystal structure of neurotropism-associated variable surface protein 1 (Vsp1) of Borrelia turicatae
Q24564277Crystal structure of nickel-containing superoxide dismutase reveals another type of active site
Q46542399Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an alpha-conotoxin PnIA variant.
Q34479784Crystal structure of obelin after Ca2+-triggered bioluminescence suggests neutral coelenteramide as the primary excited state
Q27679013Crystal structure of periplasmic catecholate-siderophore binding protein VctP from Vibrio cholerae at 1.7 Å resolution
Q27685148Crystal structure of peroxisomal targeting signal-2 bound to its receptor complex Pex7p-Pex21p
Q27638842Crystal structure of plant pectin methylesterase
Q42681698Crystal structure of prephenate dehydrogenase from Aquifex aeolicus. Insights into the catalytic mechanism
Q27628392Crystal structure of protein isoaspartyl methyltransferase: a catalyst for protein repair
Q27636276Crystal structure of quinohemoprotein alcohol dehydrogenase from Comamonas testosteroni: structural basis for substrate oxidation and electron transfer
Q24299686Crystal structure of rab11 in complex with rab11 family interacting protein 2
Q27639495Crystal structure of recombinant human interleukin-22
Q27640805Crystal structure of rice alpha-galactosidase complexed with D-galactose
Q40541096Crystal structure of species D adenovirus fiber knobs and their sialic acid binding sites
Q27639530Crystal structure of the 47-kDa lipoprotein of Treponema pallidum reveals a novel penicillin-binding protein
Q41866374Crystal structure of the Bowman-Birk Inhibitor from Vigna unguiculata seeds in complex with beta-trypsin at 1.55 A resolution and its structural properties in association with proteinases.
Q34323722Crystal structure of the C-terminal clock-oscillator domain of the cyanobacterial KaiA protein
Q27639906Crystal structure of the C-terminal half of tropomodulin and structural basis of actin filament pointed-end capping
Q39490343Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme
Q51052695Crystal structure of the CN-hydrolase SA0302 from the pathogenic bacterium Staphylococcus aureus belonging to the Nit and NitFhit Branch of the nitrilase superfamily.
Q27632267Crystal structure of the CheA histidine phosphotransfer domain that mediates response regulator phosphorylation in bacterial chemotaxis
Q27638843Crystal structure of the Escherichia coli SbmC protein that protects cells from the DNA replication inhibitor microcin B17
Q30160113Crystal structure of the FERM domain of focal adhesion kinase.
Q27637525Crystal structure of the GABAA-receptor-associated protein, GABARAP
Q27639121Crystal structure of the Homer 1 family conserved region reveals the interaction between the EVH1 domain and own proline-rich motif
Q30157689Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit
Q51146971Crystal structure of the N-terminal anticodon-binding domain of the nondiscriminating aspartyl-tRNA synthetase from Helicobacter pylori.
Q27684711Crystal structure of the N-terminal domain of a glycoside hydrolase family 131 protein from Coprinopsis cinerea
Q27663566Crystal structure of the P2 C-repressor: a binder of non-palindromic direct DNA repeats
Q24324478Crystal structure of the PTPL1/FAP-1 human tyrosine phosphatase mutated in colorectal cancer: evidence for a second phosphotyrosine substrate recognition pocket
Q40100747Crystal structure of the PsbP protein of photosystem II from Nicotiana tabacum.
Q27641938Crystal structure of the PsbQ protein of photosystem II from higher plants
Q34342036Crystal structure of the S-adenosylmethionine-dependent enzyme MoaA and its implications for molybdenum cofactor deficiency in humans
Q27639585Crystal structure of the YciO protein from Escherichia coli
Q24535966Crystal structure of the ankyrin repeat domain of Bcl-3: a unique member of the IkappaB protein family.
Q27650679Crystal structure of the aquaglyceroporin PfAQP from the malarial parasite Plasmodium falciparum
Q27702266Crystal structure of the bacteriophage P2 integrase catalytic domain
Q27642399Crystal structure of the bifunctional chorismate synthase from Saccharomyces cerevisiae
Q27637854Crystal structure of the carbohydrate recognition domain of p58/ERGIC-53, a protein involved in glycoprotein export from the endoplasmic reticulum
Q24600266Crystal structure of the catalytic domain of human complement c1s: a serine protease with a handle
Q27651294Crystal structure of the cell wall anchor domain of MotB, a stator component of the bacterial flagellar motor: Implications for peptidoglycan recognition
Q24645314Crystal structure of the collagen triple helix model [(Pro-Pro-Gly)(10)](3)
Q28487478Crystal structure of the conserved hypothetical protein Rv1155 from Mycobacterium tuberculosis
Q34376013Crystal structure of the cysteine-rich secretory protein stecrisp reveals that the cysteine-rich domain has a K+ channel inhibitor-like fold.
Q27631524Crystal structure of the dimeric C-terminal domain of TonB reveals a novel fold
Q30439454Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase
Q28902946Crystal structure of the flagellar sigma/anti-sigma complex sigma(28)/FlgM reveals an intact sigma factor in an inactive conformation
Q27637352Crystal structure of the functional unit of interphotoreceptor retinoid binding protein
Q27651944Crystal structure of the hexamer of human heat shock factor binding protein 1
Q27628348Crystal structure of the human acyl protein thioesterase I from a single X-ray data set to 1.5 A
Q27642262Crystal structure of the human centromere protein B (CENP-B) dimerization domain at 1.65-A resolution
Q53624433Crystal structure of the human monocyte-activating receptor, "Group 2" leukocyte Ig-like receptor A5 (LILRA5/LIR9/ILT11).
Q27634739Crystal structure of the human nuclear cap binding complex
Q27639952Crystal structure of the human supernatant protein factor
Q46384109Crystal structure of the hydroxyquinol 1,2-dioxygenase from Nocardioides simplex 3E, a key enzyme involved in polychlorinated aromatics biodegradation
Q37471300Crystal structure of the hypothetical protein TA1238 from Thermoplasma acidophilum: a new type of helical super-bundle
Q27647464Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor
Q45264602Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate
Q27649890Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain
Q24599743Crystal structure of the matrix protein VP40 from Ebola virus
Q27641919Crystal structure of the measles virus phosphoprotein domain responsible for the induced folding of the C-terminal domain of the nucleoprotein
Q27628333Crystal structure of the molybdenum cofactor biosynthesis protein MobA from Escherichia coli at near-atomic resolution
Q34666672Crystal structure of the murine cytomegalovirus MHC-I homolog m144.
Q27668134Crystal structure of the novel PaiA N-acetyltransferase from Thermoplasma acidophilum involved in the negative control of sporulation and degradative enzyme production
Q27668133Crystal structure of the novel PaiB transcriptional regulator from Geobacillus stearothermophilus
Q33980474Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA
Q27628731Crystal structure of the peptidyl-cysteine decarboxylase EpiD complexed with a pentapeptide substrate
Q24533405Crystal structure of the phosphatidylinositol 3,4-bisphosphate-binding pleckstrin homology (PH) domain of tandem PH-domain-containing protein 1 (TAPP1): molecular basis of lipid specificity
Q27651109Crystal structure of the polymerase PA(C)-PB1(N) complex from an avian influenza H5N1 virus
Q43408014Crystal structure of the polysialic acid-degrading endosialidase of bacteriophage K1F.
Q27674655Crystal structure of the primary piRNA biogenesis factor Zucchini reveals similarity to the bacterial PLD endonuclease Nuc
Q24644417Crystal structure of the protease-resistant core domain of Yersinia pestis virulence factor YopR
Q35618676Crystal structure of the protein from Arabidopsis thaliana gene At5g06450, a putative DnaQ-like exonuclease domain-containing protein with homohexameric assembly
Q42928352Crystal structure of the proximal BAH domain of the polybromo protein.
Q47991289Crystal structure of the putative cytoplasmic protein STM0279 (Hcp2) from Salmonella typhimurium
Q47880819Crystal structure of the quorum-sensing protein TraM and its interaction with the transcriptional regulator TraR.
Q27657862Crystal structure of the shutoff and exonuclease protein from the oncogenic Kaposi's sarcoma-associated herpesvirus
Q24647566Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a
Q35213068Crystal structure of the ubiquitin-associated (UBA) domain of p62 and its interaction with ubiquitin.
Q24564886Crystal structure of the von Willebrand factor A domain of human capillary morphogenesis protein 2: an anthrax toxin receptor
Q27642230Crystal structure of the yeast Phox homology (PX) domain protein Grd19p complexed to phosphatidylinositol-3-phosphate
Q27660521Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function
Q27621469Crystal structure of the zymogen form of the group A Streptococcus virulence factor SpeB: An integrin-binding cysteine protease
Q27654971Crystal structure of the    -Me type II restriction endonuclease Hpy99I with target DNA
Q46184015Crystal structure of thy1, a thymidylate synthase complementing protein from Thermotoga maritima at 2.25 A resolution
Q36458504Crystal structure of trehalose-6-phosphate phosphatase-related protein: biochemical and biological implications
Q24646931Crystal structure of truncated human βB1‐crystallin
Q40726200Crystal structure of wild-type human thrombin in the Na+-free state.
Q27930662Crystal structure of yeast Ypr118w, a methylthioribose-1-phosphate isomerase related to regulatory eIF2B subunits
Q27639347Crystal structure ofBacillus subtilis ioli shows endonuclase IV fold with altered Zn binding
Q27639348Crystal structure ofEscherichia coli EC1530, a glyoxylate induced protein YgbM
Q24300567Crystal structure study on human S100A13 at 2.0 A resolution
Q28115448Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2
Q27639238Crystal structures at atomic resolution reveal the novel concept of "electron-harvesting" as a role for the small tetraheme cytochrome c
Q27670494Crystal structures of DntR inducer binding domains in complex with salicylate offer insights into the activation of LysR-type transcriptional regulators
Q24293341Crystal structures of S100A6 in the Ca(2+)-free and Ca(2+)-bound states: the calcium sensor mechanism of S100 proteins revealed at atomic resolution
Q27680672Crystal structures of Trypanosoma brucei oligopeptidase B broaden the paradigm of catalytic regulation in prolyl oligopeptidase family enzymes
Q34676632Crystal structures of VAP1 reveal ADAMs' MDC domain architecture and its unique C-shaped scaffold
Q27646535Crystal structures of a family 19 chitinase from Brassica juncea show flexibility of binding cleft loops
Q27634518Crystal structures of a novel ferric reductase from the hyperthermophilic archaeon Archaeoglobus fulgidus and its complex with NADP+
Q27641069Crystal structures of a pantothenate synthetase fromM. tuberculosisand its complexes with substrates and a reaction intermediate
Q27643571Crystal structures of an ATP-dependent hexokinase with broad substrate specificity from the hyperthermophilic archaeon Sulfolobus tokodaii
Q44828368Crystal structures of arginine deiminase with covalent reaction intermediates; implications for catalytic mechanism.
Q27703750Crystal structures of chitin binding domains of chitinase from Thermococcus kodakarensis KOD1
Q50108918Crystal structures of chloroperoxidase with its bound substrates and complexed with formate, acetate, and nitrate.
Q37471306Crystal structures of delta1-pyrroline-5-carboxylate reductase from human pathogens Neisseria meningitides and Streptococcus pyogenes.
Q27641843Crystal structures of engrailed homeodomain mutants: implications for stability and dynamics
Q27656116Crystal structures of g-type lysozyme from Atlantic cod shed new light on substrate binding and the catalytic mechanism
Q34514460Crystal structures of gamma-glutamyltranspeptidase from Escherichia coli, a key enzyme in glutathione metabolism, and its reaction intermediate
Q27684300Crystal structures of glycoside hydrolase family 3 β-glucosidase 1 from Aspergillus aculeatus
Q24338623Crystal structures of human SIRT3 displaying substrate-induced conformational changes
Q27678305Crystal structures of multidrug-resistant HIV-1 protease in complex with two potent anti-malarial compounds
Q27670421Crystal structures of open and closed forms of d-serine deaminase from Salmonella typhimurium - implications on substrate specificity and catalysis
Q27677942Crystal structures of putative phosphoglycerate kinases from B. anthracis and C. jejuni
Q27641498Crystal structures of the ATPase subunit of the glucose ABC transporter from Sulfolobus solfataricus: nucleotide-free and nucleotide-bound conformations
Q34828345Crystal structures of the DsbG disulfide isomerase reveal an unstable disulfide.
Q41308269Crystal structures of the Gon7/Pcc1 and Bud32/Cgi121 complexes provide a model for the complete yeast KEOPS complex
Q27678211Crystal structures of the Tudor domains of human PHF20 reveal novel structural variations on the Royal Family of proteins
Q27650835Crystal structures of the effector-binding domain of repressor Central glycolytic gene Regulator fromBacillus subtilisreveal ligand-induced structural changes upon binding of several glycolytic intermediates
Q27667505Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming
Q27641971Crystal structures of the liganded and unliganded nickel-binding protein NikA from Escherichia coli
Q27652885Crystal structures of the organomercurial lyase MerB in its free and mercury-bound forms: insights into the mechanism of methylmercury degradation
Q27677450Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life
Q36476624Crystal structures of the tryptophan repressor binding protein WrbA and complexes with flavin mononucleotide
Q30342172Crystal structures of two cyanobacterial response regulators in apo- and phosphorylated form reveal a novel dimerization motif of phytochrome-associated response regulators.
Q35585795Crystal structures of two putative phosphoheptose isomerases.
Q24618513Crystal structures that suggest late development of genetic code components for differentiating aromatic side chains
Q36591772Crystallization and X-ray diffraction analysis of a novel immune-type receptor from Ictalurus punctatus and phasing by selenium anomalous dispersion methods.
Q27646708Crystallization and X-ray structure of cold-shock protein E fromSalmonella typhimurium
Q42132846Crystallization and calcium/sulfur SAD phasing of the human EF-hand protein S100A2.
Q42154336Crystallization and crystallographic analysis of the ligand-binding domain of the Pseudomonas putida chemoreceptor McpS in complex with malate and succinate
Q41909720Crystallization and molecular-replacement studies of the monoclonal antibody mAbR310 specific for the (R)-HNE-modified protein
Q41961169Crystallization and preliminary X-ray analysis of a cohesin-like module from AF2375 of the archaeon Archaeoglobus fulgidus.
Q42949106Crystallization and preliminary X-ray analysis of cytochrome c nitrite reductase from Thioalkalivibrio nitratireducens.
Q39643155Crystallization and preliminary X-ray analysis of peptidyl-tRNA hydrolase from Escherichia coli in complex with the acceptor-TΨC domain of tRNA
Q39013688Crystallization and preliminary X-ray analysis of the RPB5 subunit of human RNA polymerase II
Q41542808Crystallization and preliminary X-ray crystallographic analysis of Sulfolobus solfataricus thioredoxin reductase
Q42371000Crystallization and preliminary X-ray crystallographic analysis of the Sulfolobus solfataricus nucleotide-exchange factor 1beta.
Q41974186Crystallization and preliminary X-ray crystallographic analysis of two dimeric hyperthermostable thioredoxins isolated from Sulfolobus solfataricus.
Q42836612Crystallization and preliminary X-ray diffraction studies of the (R)-selective amine transaminase from Aspergillus fumigatus
Q41260819Crystallization and preliminary crystallographic analysis of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus
Q42000878Crystallization and preliminary crystallographic studies of putative RNA 3'-terminal phosphate cyclase from the crenarchaeon Sulfolobus tokodaii
Q42001104Crystallization and preliminary crystallographic studies of putative threonyl-tRNA synthetases from Aeropyrum pernix and Sulfolobus tokodaii
Q27673385Crystallographic Snapshots of Tyrosine Phenol-lyase Show That Substrate Strain Plays a Role in C–C Bond Cleavage
Q27657036Crystallographic ab initio protein structure solution below atomic resolution
Q27675121Crystallographic and X-ray absorption spectroscopic characterization of Helicobacter pylori UreE bound to Ni 2+ and Zn 2+ reveals a role for the disordered C-terminal arm in metal trafficking
Q27655782Crystallographic and mutational analyses of substrate recognition of endo-alpha-N-acetylgalactosaminidase from Bifidobacterium longum
Q30942706Crystallographic and mutational data show that the streptococcal pyrogenic exotoxin J can use a common binding surface for T-cell receptor binding and dimerization
Q36407777Crystallographic structure of the nuclease domain of 3'hExo, a DEDDh family member, bound to rAMP.
Q27648680Crystallographic studies of human MitoNEET
Q42000466Crystallographic study of wild-type carbonic anhydrase alpha CA1 from Chlamydomonas reinhardtii
Q27665912Cyclic AMP Analog Blocks Kinase Activation by Stabilizing Inactive Conformation: Conformational Selection Highlights a New Concept in Allosteric Inhibitor Design
Q27640625Cytochrome c nitrite reductase from Desulfovibrio desulfuricans ATCC 27774. The relevance of the two calcium sites in the structure of the catalytic subunit (NrfA)
Q27643705DNA binding mechanism revealed by high resolution crystal structure of Arabidopsis thaliana WRKY1 protein
Q34302323DNA recognition by a σ(54) transcriptional activator from Aquifex aeolicus
Q58321492Data Analysis: Keeping Pace with Extraordinary Change
Q27679789Deamination of 6-Aminodeoxyfutalosine in Menaquinone Biosynthesis by Distantly Related Enzymes
Q34500858Deciphering the structural framework of glycine receptor anchoring by gephyrin
Q29616440Decision-making in structure solution using Bayesian estimates of map quality: the PHENIX AutoSol wizard
Q34809121Deletion of C7L and K1L genes leads to significantly decreased virulence of recombinant vaccinia virus TianTan
Q27650133Design of an engineered N-terminal HIV-1 gp41 trimer with enhanced stability and potency
Q27650469Determination of protein structures--a series of fortunate events
Q30351263Determining relevant features to recognize electron density patterns in x-ray protein crystallography.
Q27681127Development and binding characteristics of phosphonate inhibitors of SplA protease from Staphylococcus aureus
Q35636414Development of a shutterless continuous rotation method using an X-ray CMOS detector for protein crystallography
Q46923707Development of the signal in sensory rhodopsin and its transfer to the cognate transducer
Q56534201Dextranase from Penicillium minioluteum
Q27656489Differential Recognition and Hydrolysis of Host Carbohydrate Antigens by Streptococcus pneumoniae Family 98 Glycoside Hydrolases
Q27635158Differential dimer activities of the transcription factor Oct-1 by DNA-induced interface swapping
Q27639219Differential oligosaccharide recognition by evolutionarily-related beta-1,4 and beta-1,3 glucan-binding modules
Q27628357Dimeric structure of the coxsackievirus and adenovirus receptor D1 domain at 1.7 A resolution
Q27650780Dimerization effect of sucrose octasulfate on rat FGF1
Q27656916Dimerization of Hepatitis E Virus Capsid Protein E2s Domain Is Essential for Virus–Host Interaction
Q27660790Discovery and Structure Determination of the Orphan Enzyme Isoxanthopterin Deaminase,
Q27644677Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium tuberculosis That Target Leucyl-tRNA Synthetase
Q27680134Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual Screening
Q33684957Discovery of a novel L-lyxonate degradation pathway in Pseudomonas aeruginosa PAO1.
Q46276845Discovery of α-L-arabinopyranosidases from human gut microbiome expands the diversity within glycoside hydrolase family 42.
Q33944428Disordered to ordered folding in the regulation of diphtheria toxin repressor activity
Q30278363Dissecting the Structural Elements for the Activation of β-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae
Q33804706Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia
Q92513880Distinctive ligand-binding specificities of tandem PA14 biomass-sensory elements from Clostridium thermocellum and Clostridium clariflavum
Q30401434Distributed structure determination at the JCSG.
Q27649908Divergent Modes of Glycan Recognition by a New Family of Carbohydrate-binding Modules
Q30378529Diversity in the structures and ligand-binding sites of nematode fatty acid and retinol-binding proteins revealed by Na-FAR-1 from Necator americanus
Q34083739Does NMR mean "not for molecular replacement"? Using NMR-based search models to solve protein crystal structures
Q27648746Domain Swapping within PDZ2 Is Responsible for Dimerization of ZO Proteins
Q27639107Domain-swapped structure of a mutant of cyanovirin-N
Q34547829Domain-swapped structure of the potent antiviral protein griffithsin and its mode of carbohydrate binding.
Q30370754Double trouble-Buffer selection and His-tag presence may be responsible for nonreproducibility of biomedical experiments.
Q27681935Dual kinase-bromodomain inhibitors for rationally designed polypharmacology
Q27642989Dual, HLA-B27 Subtype-dependent Conformation of a Self-peptide
Q34116221Dual-mode recognition of noncanonical tRNAs(Ser) by seryl-tRNA synthetase in mammalian mitochondria
Q35223123E pluribus unum, no more: from one crystal, many conformations
Q36073783Effect of BET Missense Mutations on Bromodomain Function, Inhibitor Binding and Stability
Q31108222Effect of impurities and post-experimental purification in SAD phasing with serial femtosecond crystallography data
Q27646517Electrostatic Interactions of Hsp-organizing Protein Tetratricopeptide Domains with Hsp70 and Hsp90: COMPUTATIONAL ANALYSIS AND PROTEIN ENGINEERING
Q27645072Engineering of PA-IIL lectin from Pseudomonas aeruginosa – Unravelling the role of the specificity loop for sugar preference
Q27694964Engineering specificity in a dynamic protein complex with a single conserved mutation
Q30327989Entering a new phase: using solvent halide ions in protein structure determination.
Q27641892Essential roles of zinc ligation and enzyme dimerization for catalysis in the aminoacylase-1/M20 family
Q27652738Evf, a virulence factor produced by the Drosophila pathogen Erwinia carotovora, is an S-palmitoylated protein with a new fold that binds to lipid vesicles
Q27671628Evidence for a Two-Metal-Ion Mechanism in the Cytidyltransferase KdsB, an Enzyme Involved in Lipopolysaccharide Biosynthesis
Q27666360Evolution in a family of chelatases facilitated by the introduction of active site asymmetry and protein oligomerization
Q27679273Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis
Q27650066Expansion of substrate specificity and catalytic mechanism of azoreductase by X-ray crystallography and site-directed mutagenesis
Q27671961Experimental phasing using zinc anomalous scattering
Q27860790Experimental phasing with SHELXC/D/E: combining chain tracing with density modification
Q27644308Exploring subdomain cooperativity in T4 lysozyme I: Structural and energetic studies of a circular permutant and protein fragment
Q33877204Expression, crystallization and preliminary X-ray data analysis of NT-Als9-2, a fungal adhesin from Candida albicans.
Q42411839Expression, purification, crystallization and preliminary X-ray analysis of YaeQ (XAC2396) from Xanthomonas axonopodis pv. citri.
Q42860212Expression, purification, crystallization and preliminary X-ray analysis of the human RuvB-like protein RuvBL1.
Q24604680Expression, purification, crystallization and preliminary crystallographic studies of Rhagium inquisitor antifreeze protein
Q27643861Factor B structure provides insights into activation of the central protease of the complement system
Q27657785Fatty Acid- and Retinoid-binding Proteins Have Distinct Binding Pockets for the Two Types of Cargo
Q64986911Features and structure of a cold active N-acetylneuraminate lyase.
Q27689091Fine-structural variance of family 3 carbohydrate-binding modules as extracellular biomass-sensing components of Clostridium thermocellum anti-σI factors
Q24306216First crystallographic models of human TBC domains in the context of a family-wide structural analysis
Q54460051Formate-reduced E. coli formate dehydrogenase H: The reinterpretation of the crystal structure suggests a new reaction mechanism.
Q35215396From clone to crystal: maximizing the amount of protein samples for structure determination.
Q30660474Fully automatic characterization and data collection from crystals of biological macromolecules
Q27658101Function-biased choice of additives for optimization of protein crystallization - the case of the putative thioesterase PA5185 from Pseudomonas aeruginosa PAO1
Q27653489Functional Annotation and Three-Dimensional Structure of Dr0930 from Deinococcus radiodurans , a Close Relative of Phosphotriesterase in the Amidohydrolase Superfamily † ‡
Q27654600Functional Annotation of Two New Carboxypeptidases from the Amidohydrolase Superfamily of Enzymes
Q35662809Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases from Saccharomyces cerevisiae: BIOCHEMICAL, STRUCTURAL, AND EVOLUTIONARY INSIGHTS.
Q27650545Functional and Structural Characterization of Four Glutaminases from Escherichia coli and Bacillus subtilis †
Q27690135Functional and molecular features of the calmodulin-interacting protein IQCG required for haematopoiesis in zebrafish
Q48083197Functional and structural aspects of poplar cytosolic and plastidial type a methionine sulfoxide reductases
Q27653000Functional and structural characterization of the integrase from the prototype foamy virus
Q36525244Functional annotation and three-dimensional structure of an incorrectly annotated dihydroorotase from cog3964 in the amidohydrolase superfamily
Q27655871Functional importance of Crenarchaea-specific extra-loop revealed by an X-ray structure of a heterotetrameric crenarchaeal splicing endonuclease
Q27646052Functional specialization of domains tandemly duplicated within 16S rRNA methyltransferase RsmC
Q27674861GES-18, a New Carbapenem-Hydrolyzing GES-Type  -Lactamase from Pseudomonas aeruginosa That Contains Ile80 and Ser170 Residues
Q27675170Gating of the designed trimeric/tetrameric voltage-gated H+channel
Q27639621Gene sequence and the 1.8 A crystal structure of the tungsten-containing formate dehydrogenase from Desulfovibrio gigas
Q27660402Globin-like proteins in Caenorhabditis elegans: in vivo localization, ligand binding and structural properties
Q27639914GluR2 ligand-binding core complexes: importance of the isoxazolol moiety and 5-substituent for the binding mode of AMPA-type agonists
Q27666371Glutathione Transferases of Phanerochaete chrysosporium: S-GLUTATHIONYL-p-HYDROQUINONE REDUCTASE BELONGS TO A NEW STRUCTURAL CLASS
Q27666510Glycine amide shielding on the aromatic surfaces of lysozyme: implication for suppression of protein aggregation
Q27642487Gram-positive DsbE proteins function differently from Gram-negative DsbE homologs. A structure to function analysis of DsbE from Mycobacterium tuberculosis
Q27654484Group B Streptococcus Pullulanase Crystal Structures in the Context of a Novel Strategy for Vaccine Development
Q27639674HLA-B27 subtypes differentially associated with disease exhibit subtle structural alterations
Q30433615Harvesting the high-hanging fruit: the structure of the YdeN gene product from Bacillus subtilis at 1.8 angstroms resolution
Q35055587Helical shape of Helicobacter pylori requires an atypical glutamine as a zinc ligand in the carboxypeptidase Csd4
Q27626606Heparan/chondroitin sulfate biosynthesis. Structure and mechanism of human glucuronyltransferase I
Q45091600Hexameric assembly of the bifunctional methylerythritol 2,4-cyclodiphosphate synthase and protein-protein associations in the deoxy-xylulose-dependent pathway of isoprenoid precursor biosynthesis
Q27651455High Affinity Interaction between a Bivalve C-type Lectin and a Biantennary Complex-type N-Glycan Revealed by Crystallography and Microcalorimetry
Q27682725High resolution crystal structure of Sco5413, a widespread actinomycete MarR family transcriptional regulator of unknown function
Q37522439High resolution crystal structure of the catalytic domain of MCR-1.
Q27639475High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site
Q27639982High resolution crystal structures of Siglec-7. Insights into ligand specificity in the Siglec family
Q27648497High resolution structure and catalysis of O-acetylserine sulfhydrylase isozyme B from Escherichia coli
Q27627517High resolution structure of the phosphohistidine-activated form of Escherichia coli cofactor-dependent phosphoglycerate mutase
Q27640685High-resolution X-ray and NMR structures of the SMN Tudor domain: conformational variation in the binding site for symmetrically dimethylated arginine residues
Q27641428High-resolution structure of RNase P protein from Thermotoga maritima
Q27671054High-resolution structure of a new crystal form of BamA POTRA4–5 fromEscherichia coli
Q27686989High-resolution structure of a papaya plant-defense barwin-like protein solved by in-house sulfur-SAD phasing
Q34120510High-resolution structure of the catalytic region of MICAL (molecule interacting with CasL), a multidomain flavoenzyme-signaling molecule
Q27639493High-resolution structure of the pleckstrin homology domain of protein kinase b/akt bound to phosphatidylinositol (3,4,5)-trisphosphate
Q24646937High-resolution structure prediction and the crystallographic phase problem
Q27675648High-resolution structures of AidH complexes provide insights into a novel catalytic mechanism forN-acyl homoserine lactonase
Q27641399High-resolution structures of RmlC from Streptococcus suis in complex with substrate analogs locate the active site of this class of enzyme
Q27644930High-resolution structures of formate dehydrogenase fromCandida boidinii
Q51620562High-throughput crystallization-to-structure pipeline at RIKEN SPring-8 Center.
Q30331190High-throughput crystallography for lead discovery in drug design.
Q30328636High-throughput three-dimensional protein structure determination.
Q27665402Homologue structure of the SLAC1 anion channel for closing stomata in leaves
Q27651972Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase PB2 Subunit
Q27658743How Much Binding Affinity Can be Gained by Filling a Cavity?
Q46574978How family 26 glycoside hydrolases orchestrate catalysis on different polysaccharides: structure and activity of a Clostridium thermocellum lichenase, CtLic26A.
Q27664652Human OGA binds substrates in a conserved peptide recognition groove
Q27675671Human Suv3 protein reveals unique features among SF2 helicases
Q24312786IQGAP proteins reveal an atypical phosphoinositide (aPI) binding domain with a pseudo C2 domain fold
Q27711232Identification and characterization of a bacterial hyaluronidase and its production in recombinant form
Q27643400Identification and structural basis of binding to host lung glycogen by streptococcal virulence factors
Q24301596Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis
Q58691730Identification of a novel zinc-binding protein, C1orf123, as an interactor with a heavy metal-associated domain
Q38341009Identification of functional residues on Caenorhabditis elegans actin-interacting protein 1 (UNC-78) for disassembly of actin depolymerizing factor/cofilin-bound actin filaments
Q27636152Identification, characterization, and crystal structure of Bacillus subtilis nicotinic acid mononucleotide adenylyltransferase
Q27650961Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes
Q36073490Improved crystallographic models through iterated local density-guided model deformation and reciprocal-space refinement
Q37351114Improving macromolecular atomic models at moderate resolution by automated iterative model building, statistical density modification and refinement
Q37415680In different organisms, the mode of interaction between two signaling proteins is not necessarily conserved
Q42183036In praise of impurity: 30S ribosomal S15 protein-assisted crystallization of turnip yellow mosaic virus proteinase
Q27704826In vitro heme biotransformation by the HupZ enzyme from Group A streptococcus
Q27650544In vitro reconstitution and crystal structure of p-aminobenzoate N-oxygenase (AurF) involved in aureothin biosynthesis
Q27652980Incompatibility with Formin Cdc12p Prevents Human Profilin from Substituting for Fission Yeast Profilin: INSIGHTS FROM CRYSTAL STRUCTURES OF FISSION YEAST PROFILIN
Q27661330Induced-fit mechanism for prolyl endopeptidase
Q47162787Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine.
Q27650694Inhibition of the glucosyltransferase activity of clostridial Rho/Ras-glucosylating toxins by castanospermine
Q27315848Initiation of T cell signaling by CD45 segregation at 'close contacts'
Q27676482Insight into S -adenosylmethionine biosynthesis from the crystal structures of the human methionine adenosyltransferase catalytic and regulatory subunits
Q30275606Insight into the 3D structure and substrate specificity of previously uncharacterized GNAT superfamily acetyltransferases from pathogenic bacteria
Q24319669Insights into DNA recombination from the structure of a RAD51-BRCA2 complex
Q27646432Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex
Q27637371Insights into enzyme evolution revealed by the structure of methylaspartate ammonia lyase
Q27641337Insights into ssDNA recognition by the OB fold from a structural and thermodynamic study of Sulfolobus SSB protein
Q27651715Insights into the Catalytic Mechanism of Tyrosine Phenol-lyase from X-ray Structures of Quinonoid Intermediates
Q27667119Insights into the Function of the CRM1 Cofactor RanBP3 from the Structure of Its Ran-Binding Domain
Q44795452Insights into the molecular determinants of substrate specificity in glycoside hydrolase family 5 revealed by the crystal structure and kinetics of Cellvibrio mixtus mannosidase 5A.
Q58038949Insights into the relationship between the haem-binding pocket and the redox potential ofc6cytochromes: four atomic resolution structures ofc6andc6-like proteins fromSynechococcussp. PCC 7002
Q34598232Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates
Q34489798Insights into voltage-gated calcium channel regulation from the structure of the CaV1.2 IQ domain-Ca2+/calmodulin complex
Q27641156Integrating Structure, Bioinformatics, and Enzymology to Discover Function: BioH, A NEW CARBOXYLESTERASE FROM ESCHERICHIA COLI
Q47788364Interactions of calmodulin with death-associated protein kinase peptides: experimental and modeling studies
Q63979648Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains
Q36790438Interpretation of ensembles created by multiple iterative rebuilding of macromolecular models
Q27649108Intrinsic motions along an enzymatic reaction trajectory
Q27653933Involvement of a carboxylated lysine in UV damage endonuclease
Q28131661Iterative model building, structure refinement and density modification with the PHENIX AutoBuild wizard
Q36713744Iterative-build OMIT maps: map improvement by iterative model building and refinement without model bias
Q27671606Kinetic and Crystallographic Studies of Extended-Spectrum GES-11, GES-12, and GES-14  -Lactamases
Q28492217Kinetic and structural insights into the mechanism of AMPylation by VopS Fic domain
Q42095354Kinetic, inhibition and structural studies on 3-oxoacyl-ACP reductase from Plasmodium falciparum, a key enzyme in fatty acid biosynthesis
Q24314691Klotho-related protein is a novel cytosolic neutral beta-glycosylceramidase
Q27676039Large FK506-Binding Proteins Shape the Pharmacology of Rapamycin
Q27659245Large-scale Domain Dynamics and Adenosylcobalamin Reorientation Orchestrate Radical Catalysis in Ornithine 4,5-Aminomutase
Q27010394Lessons from structural genomics
Q56877898Ligand Electron Density Shape Recognition Using 3D Zernike Descriptors
Q27676497Long-range Electrostatic Complementarity Governs Substrate Recognition by Human Chymotrypsin C, a Key Regulator of Digestive Enzyme Activation
Q64237702Long-wavelength Mesh&Collect native SAD phasing from microcrystals
Q27666781Loss of recognition by cross-reactive T cells and its relation to a C-terminus-induced conformational reorientation of an HLA-B*2705-bound peptide
Q36390384Low Resolution Refinement of Atomic Models Against Crystallographic Data.
Q28486885LppX is a lipoprotein required for the translocation of phthiocerol dimycocerosates to the surface of Mycobacterium tuberculosis
Q30332071MAMMOTH (matching molecular models obtained from theory): an automated method for model comparison
Q27677863Macro-to-Micro Structural Proteomics: Native Source Proteins for High-Throughput Crystallization
Q27635933Maintenance of an unfolded polypeptide by a cognate chaperone in bacterial type III secretion
Q27643755Mannose foraging by Bacteroides thetaiotaomicron: structure and specificity of the beta-mannosidase, BtMan2A
Q37351137Map-likelihood phasing
Q27678085Matrix Metalloproteinase-10 (MMP-10) Interaction with Tissue Inhibitors of Metalloproteinases TIMP-1 and TIMP-2: BINDING STUDIES AND CRYSTAL STRUCTURE
Q28364738Maximum-likelihood density modification using pattern recognition of structural motifs
Q27670614Mdm38 is a 14-3-3-like receptor and associates with the protein synthesis machinery at the inner mitochondrial membrane
Q27656024Mechanism for the Hydrolysis of a Sulfur-Sulfur Bond Based on the Crystal Structure of the Thiosulfohydrolase SoxB
Q36485301Mechanism of CREB recognition and coactivation by the CREB-regulated transcriptional coactivator CRTC2
Q24534544Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase
Q24550963Mechanism of action of a flavin-containing monooxygenase
Q27636255Mechanism of ubiquitin activation revealed by the structure of a bacterial MoeB-MoaD complex
Q64060598Mechanisms of redundancy and specificity of the Aspergillus fumigatus Crh transglycosylases
Q27679345Mechanistic Insights into Regulated Cargo Binding by ACAP1 Protein
Q27653166Mechanistic Insights into the Hydrolysis and Synthesis of Ceramide by Neutral Ceramidase
Q27640940Methyltransferase That Modifies Guanine 966 of the 16 S rRNA: FUNCTIONAL IDENTIFICATION AND TERTIARY STRUCTURE
Q24671640MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone
Q37280214Model morphing and sequence assignment after molecular replacement
Q33505472Modeling discrete heterogeneity in X-ray diffraction data by fitting multi-conformers
Q27678830Molecular Architecture of the Ankyrin SOCS Box Family of Cul5-Dependent E3 Ubiquitin Ligases
Q27654035Molecular Basis of Arabinobio-hydrolase Activity in Phytopathogenic Fungi: CRYSTAL STRUCTURE AND CATALYTIC MECHANISM OF FUSARIUM GRAMINEARUM GH93 EXO- -L-ARABINANASE
Q27662700Molecular Characterization of a Class I P450 Electron Transfer System from Novosphingobium aromaticivorans DSM12444
Q27653194Molecular Mechanisms of Yeast Cell Wall Glucan Remodeling
Q27666685Molecular and structural basis of ESCRT-III recruitment to membranes during archaeal cell division
Q27677427Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres
Q27641772Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains
Q46465766Molecular basis of intramolecular electron transfer in sulfite-oxidizing enzymes is revealed by high resolution structure of a heterodimeric complex of the catalytic molybdopterin subunit and a c-type cytochrome subunit
Q27639365Molecular basis of mitomycin C resistance in streptomyces: structure and function of the MRD protein
Q27647509Molecular basis of the activity of the phytopathogen pectin methylesterase
Q24657851Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-A structure of the heparin-bridged complex
Q27680420Molecular characterization of monoclonal antibodies that inhibit acetylcholinesterase by targeting the peripheral site and backdoor region
Q27644441Molecular implications of evolutionary differences in CHD double chromodomains
Q41813798Molecular insights into the interaction of the ribosomal stalk protein with elongation factor 1α.
Q27658750Molecular mechanism of elongation factor 1A inhibition by a Legionella pneumophila glycosyltransferase
Q27650770Molecular mechanism of energy conservation in polysulfide respiration
Q27640909Molecular mechanism of membrane recruitment of GGA by ARF in lysosomal protein transport
Q30329498Molecular modelling in structural biology.
Q27640994Moth chemosensory protein exhibits drastic conformational changes and cooperativity on ligand binding
Q38606560MrBUMP: an automated pipeline for molecular replacement
Q27653883Multifunctionality and mechanism of ligand binding in a mosquito antiinflammatory protein
Q27660526Mutation of Archaeal Isopentenyl Phosphate Kinase Highlights Mechanism and Guides Phosphorylation of Additional Isoprenoid Monophosphates
Q24650011Mutation of interfaces in domain-swapped human betaB2-crystallin
Q27682784Mutational and crystallographic analysis ofl-amino acid oxidase/monooxygenase fromPseudomonassp. AIU 813: Interconversion between oxidase and monooxygenase activities
Q27655825Mutations of key hydrophobic surface residues of 11β-hydroxysteroid dehydrogenase type 1 increase solubility and monodispersity in a bacterial expression system
Q27649360Mycobacterium tuberculosis CYP130: CRYSTAL STRUCTURE, BIOPHYSICAL CHARACTERIZATION, AND INTERACTIONS WITH ANTIFUNGAL AZOLE DRUGS
Q54977853Myroilysin Is a New Bacterial Member of the M12A Family of Metzincin Metallopeptidases and Is Activated by a Cysteine Switch Mechanism.
Q27655409N-Acetylglucosamine Recognition by a Family 32 Carbohydrate-Binding Module from Clostridium perfringens NagH
Q35565948N-myristoyltransferase is a cell wall target in Aspergillus fumigatus
Q27650169N15 Cro and lambda Cro: orthologous DNA-binding domains with completely different but equally effective homodimer interfaces
Q27639031NAD binding induces conformational changes in Rho ADP-ribosylating clostridium botulinum C3 exoenzyme
Q27727699NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine
Q24801634Native interface of the SAM domain polymer of TEL.
Q35024047New antiviral target revealed by the hexameric structure of mouse hepatitis virus nonstructural protein nsp15.
Q27652073New insights into intra- and intermolecular interactions of immunoglobulins: crystal structure of mouse IgG2b-Fc at 2·1-Å resolution
Q34242649New structural forms of a mycobacterial adenylyl cyclase Rv1625c
Q27640664Ni-Zn-[Fe4-S4] and Ni-Ni-[Fe4-S4] clusters in closed and open subunits of acetyl-CoA synthase/carbon monoxide dehydrogenase
Q21145891Nicotinamide riboside kinase structures reveal new pathways to NAD+
Q27681886Niemann-Pick type C2 protein mediating chemical communication in the worker ant
Q27665113Noncellulosomal cohesin from the hyperthermophilic archaeon Archaeoglobus fulgidus
Q24305202Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation
Q27666434Novel structure of an N-terminal domain that is crucial for the dimeric assembly and DNA-binding of an archaeal DNA polymerase D large subunit from Pyrococcus horikoshii
Q34645464Nucleotide binding to human UMP-CMP kinase using fluorescent derivatives -- a screening based on affinity for the UMP-CMP binding site
Q27652562Nucleotide-binding flexibility in ultrahigh-resolution structures of the SRP GTPase Ffh
Q30445728Nup50/Npap60 function in nuclear protein import complex disassembly and importin recycling
Q27660109ORF157 from the Archaeal Virus Acidianus Filamentous Virus 1 Defines a New Class of Nuclease
Q27645667Oligomerization of BenM, a LysR-type transcriptional regulator: structural basis for the aggregation of proteins in this family
Q27660359Omp85 from the Thermophilic Cyanobacterium Thermosynechococcus elongatus Differs from Proteobacterial Omp85 in Structure and Domain Composition
Q36244382On the accuracy of unit-cell parameters in protein crystallography
Q42575593On the combination of molecular replacement and single-wavelength anomalous diffraction phasing for automated structure determination
Q41446369On the structure of the stator of the mitochondrial ATP synthase
Q27643832Open and closed structures of the UDP-glucose pyrophosphorylase from Leishmania major
Q27641195Origins of peptide selectivity and phosphoinositide binding revealed by structures of disabled-1 PTB domain complexes
Q41917232Overexpression, purification, crystallization and preliminary X-ray crystallographic studies of a proline-specific aminopeptidase from Aneurinibacillus sp. strain AM-1
Q42244497Overproduction, purification, crystallization and preliminary X-ray characterization of a novel carbohydrate-binding module of endoglucanase Cel5A from Eubacterium cellulosolvens.
Q27630743Oxyanion binding alters conformation and quaternary structure of the c-terminal domain of the transcriptional regulator mode. Implications for molybdate-dependent regulation, signaling, storage, and transport
Q24312088PB1 domain-mediated heterodimerization in NADPH oxidase and signaling complexes of atypical protein kinase C with Par6 and p62
Q27640904PDZ tandem of human syntenin: crystal structure and functional properties
Q27663641Papain-Like Protease 1 from Transmissible Gastroenteritis Virus: Crystal Structure and Enzymatic Activity toward Viral and Cellular Substrates
Q46825053Paratope determination of the antithrombotic antibody 82D6A3 based on the crystal structure of its complex with the von Willebrand factor A3-domain
Q27646152Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid
Q27637718Passive acquisition of ligand by the MopII molbindin from Clostridium pasteurianum: structures of apo and oxyanion-bound forms
Q30384389Peptide binding to a bacterial signal peptidase visualized by peptide tethering and carrier-driven crystallization
Q75209504Phasing on rapidly soaked ions
Q27684591Phosphates in the Z-DNA dodecamer are flexible, but their P-SAD signal is sufficient for structure solution
Q27652030PilF Is an Outer Membrane Lipoprotein Required for Multimerization and Localization of the Pseudomonas aeruginosa Type IV Pilus Secretin
Q37631800Polder maps: improving OMIT maps by excluding bulk solvent.
Q27646511Prediction and assignment of function for a divergent N-succinyl amino acid racemase
Q92364588Prediction of models for ordered solvent in macromolecular structures by a classifier based upon resolution-independent projections of local feature data
Q38272976Preliminary X-ray characterization of a novel type of anchoring cohesin from the cellulosome of Ruminococcus flavefaciens
Q35950572Preliminary crystallographic analysis of ADP-glucose pyrophosphorylase from Agrobacterium tumefaciens
Q24319024Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression
Q30419320Probabilistic ensembles for improved inference in protein-structure determination
Q37334404Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia.
Q43193151Prospects for de novo phasing with de novo protein models
Q28647499Protein Crystallography from the Perspective of Technology Developments
Q30409760Protein crystallography for aspiring crystallographers or how to avoid pitfalls and traps in macromolecular structure determination
Q27649711Protein crystallography with a micrometre-sized synchrotron-radiation beam
Q30364487Protein phasing at non-atomic resolution by combining Patterson and VLD techniques.
Q35607334Protein structures at atomic resolution
Q27662061Prp43p contains a processive helicase structural architecture with a specific regulatory domain
Q47148465Psoriasis pathogenesis - Pso p27 constitutes a compact structure forming large aggregates
Q42124759Purification, crystallization and preliminary crystallographic analysis of banyan peroxidase
Q27860905REFMAC5 for the refinement of macromolecular crystal structures
Q27645082RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors
Q55077521RING tetramerization is required for nuclear body biogenesis and PML sumoylation.
Q42866758RNABC: forward kinematics to reduce all-atom steric clashes in RNA backbone
Q33682980Rapid chain tracing of polypeptide backbones in electron-density maps
Q24643501Rapid model building of alpha-helices in electron-density maps
Q33682973Rapid model building of beta-sheets in electron-density maps
Q27645469Rational Conversion of Substrate and Product Specificity in a Salvia Monoterpene Synthase: Structural Insights into the Evolution of Terpene Synthase Function
Q27666020Rational Design of Inhibitors and Activity-Based Probes Targeting Clostridium difficile Virulence Factor TcdB
Q33403171Re-refinement from deposited X-ray data can deliver improved models for most PDB entries
Q42585595Reassembly and co-crystallization of a family 9 processive endoglucanase from its component parts: structural and functional significance of the intermodular linker
Q34066538Recent developments in software for the automation of crystallographic macromolecular structure determination
Q27684566Recent progress in robot-based systems for crystallography and their contribution to drug discovery
Q27653123Recognition and repair of UV lesions in loop structures of duplex DNA by DASH-type cryptochrome
Q27655495Recognition of AT-Rich DNA Binding Sites by the MogR Repressor
Q27664388Recognition of the Helical Structure of  -1,4-Galactan by a New Family of Carbohydrate-binding Modules
Q42709189Reduction of density-modification bias by β correction.
Q53619114Regulation of the Dha operon of Lactococcus lactis: a deviation from the rule followed by the Tetr family of transcription regulators.
Q42079214Resolution-adapted recombination of structural features significantly improves sampling in restraint-guided structure calculation
Q54454190Respective importance of protein folding and glycosylation in the thermal stability of recombinant feruloyl esterase A.
Q27650474Revealing the moonlighting role of NADP in the structure of a flavin-containing monooxygenase
Q27649408RhaU of Rhizobium leguminosarum Is a Rhamnose Mutarotase
Q27316687RoboDiff: combining a sample changer and goniometer for highly automated macromolecular crystallography experiments
Q27651684Ruffling of Metalloporphyrins Bound to IsdG and IsdI, Two Heme-degrading Enzymes in Staphylococcus aureus
Q27722821S-Nitrosylation Induces Structural and Dynamical Changes in a Rhodanese Family Protein
Q27684212SHP family protein tyrosine phosphatases adopt canonical active-site conformations in the apo and phosphate-bound states
Q27860481SOLVE and RESOLVE: automated structure solution and density modification
Q27655841ST1710-DNA complex crystal structure reveals the DNA binding mechanism of the MarR family of regulators
Q57979697SUMO modification of the ubiquitin-conjugating enzyme E2-25K
Q78057863Selenium-based MAD phasing: setting the sites on larger structures
Q27655111Selenomethionine incorporation in proteins expressed inLactococcus lactis
Q36520477Serological, genomic and structural analyses of the major mite allergen Der p 23.
Q34595903Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzyme
Q38310798Siglec-7 undergoes a major conformational change when complexed with the alpha(2,8)-disialylganglioside GT1b
Q30793293Simultaneous use of solution NMR and X-ray data in REFMAC5 for joint refinement/detection of structural differences
Q30446685Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A
Q27678635Small-Molecule Inhibitors of the c-Fes Protein-Tyrosine Kinase
Q24616901Small-molecule inhibition of BRDT for male contraception
Q30328668Soft X-rays, high redundancy, and proper scaling: a new procedure for automated protein structure determination via SAS.
Q27671160Solution NMR and X-ray crystal structures of Pseudomonas syringae Pspto_3016 from protein domain family PF04237 (DUF419) adopt a “double wing” DNA binding motif
Q27666758Specific CLK Inhibitors from a Novel Chemotype for Regulation of Alternative Splicing
Q34251178Specificity of Staphyloferrin B recognition by the SirA receptor from Staphylococcus aureus
Q24648142Stabilization of a binary protein complex by intein-mediated cyclization
Q41037129Standalone cohesin as a molecular shuttle in cellulosome assembly.
Q27642197Staphostatins resemble lipocalins, not cystatins in fold
Q27678435Staphylococcal biofilm-forming protein has a contiguous rod-like structure
Q27649310Staphylococcus aureus DsbA does not have a destabilizing disulfide. A new paradigm for bacterial oxidative folding
Q27664084Staphylococcus aureus elongation factor G--structure and analysis of a target for fusidic acid
Q37351107Statistical density modification using local pattern matching
Q27660863Stepwise [FeFe]-hydrogenase H-cluster assembly revealed in the structure of HydA(DeltaEFG)
Q27639997Stereoselectivity of enoyl-CoA hydratase results from preferential activation of one of two bound substrate conformers
Q27652737Streptococcus mutans SMU.623c Codes for a Functional, Metal-Dependent Polysaccharide Deacetylase That Modulates Interactions with Salivary Agglutinin
Q27635708Streptococcus pneumonia YlxR at 1.35 A shows a putative new fold
Q27653606Streptococcus pneumoniae Endohexosaminidase D, Structural and Mechanistic Insight into Substrate-assisted Catalysis in Family 85 Glycoside Hydrolases
Q27649734Structural Analyses of the Ankyrin Repeat Domain of TRPV6 and Related TRPV Ion Channels † , ‡
Q27653790Structural Analysis of Ligand Stimulation of the Histidine Kinase NarX
Q27666696Structural Analysis of Protein Folding by the Long-Chain Archaeal Chaperone FKBP26
Q27641594Structural Analysis of the Domain Interface in DrrB, a Response Regulator of the OmpR/PhoB Subfamily
Q27653985Structural Basis and Catalytic Mechanism for the Dual Functional Endo-β-N-Acetylglucosaminidase A
Q27671687Structural Basis for Antiviral Inhibition of the Main Protease, 3C, from Human Enterovirus 93
Q44412875Structural Basis for Catalysis and Substrate Specificity of Agrobacterium radiobacter N-Carbamoyl-D-amino Acid Amidohydrolase
Q27671639Structural Basis for ESCRT-III CHMP3 Recruitment of AMSH
Q27657363Structural Basis for Phototoxicity of the Genetically Encoded Photosensitizer KillerRed
Q27683789Structural Basis for Reversible Phosphorolysis and Hydrolysis Reactions of 2-O- -Glucosylglycerol Phosphorylase
Q30382812Structural Basis for Toughness and Flexibility in the C-terminal Passenger Domain of an Acinetobacter Trimeric Autotransporter Adhesin.
Q27651439Structural Basis for a Distinct Catalytic Mechanism in Trypanosoma brucei Tryparedoxin Peroxidase
Q27666328Structural Basis for the Oxidation of Protein-bound Sulfur by the Sulfur Cycle Molybdohemo-Enzyme Sulfane Dehydrogenase SoxCD
Q27650793Structural Basis for the Regulation Mechanism of the Tyrosine Kinase CapB from Staphylococcus aureus
Q27670708Structural Basis of Biological Nitrile Reduction
Q27676527Structural Basis of Response Regulator Inhibition by a Bacterial Anti-Activator Protein
Q27676159Structural Basis of Trypsin Inhibition and Entomotoxicity of Cospin, Serine Protease Inhibitor Involved in Defense of Coprinopsis cinerea Fruiting Bodies
Q27679365Structural Changes during Cysteine Desulfurase CsdA and Sulfur Acceptor CsdE Interactions Provide Insight into the trans -Persulfuration
Q27667447Structural Characterization and Epitope Mapping of the Glutamic Acid/Alanine-rich Protein from Trypanosoma congolense: DEFINING ASSEMBLY ON THE PARASITE CELL SURFACE
Q27678205Structural Characterization of CFA/III and Longus Type IVb Pili from Enterotoxigenic Escherichia coli
Q27678135Structural Characterization of Closely Related O-antigen Lipopolysaccharide (LPS) Chain Length Regulators
Q27654633Structural Characterization of Clostridium acetobutylicum 8-Oxoguanine DNA Glycosylase in Its Apo Form and in Complex with 8-Oxodeoxyguanosine
Q27650993Structural Characterization of Myotoxic Ecarpholin S From Echis carinatus Venom
Q27653476Structural Characterization of the Bradyzoite Surface Antigen (BSR4) from Toxoplasma gondii, a Unique Addition to the Surface Antigen Glycoprotein 1-related Superfamily
Q27661137Structural Characterization of the Predominant Family of Histidine Kinase Sensor Domains
Q27683582Structural Conservation, Variability, and Immunogenicity of the T6 Backbone Pilin of Serotype M6 Streptococcus pyogenes
Q27676731Structural Determinants for Activity and Specificity of the Bacterial Toxin LlpA
Q27677293Structural Elucidation of Dextran Degradation Mechanism by Streptococcus mutans Dextranase Belonging to Glycoside Hydrolase Family 66
Q27682073Structural Elucidation of the Cyclization Mechanism of  -1,6-Glucan by Bacillus circulans T-3040 Cycloisomaltooligosaccharide Glucanotransferase
Q27674998Structural Enzymology of Cellvibrio japonicus Agd31B Protein Reveals  -Transglucosylase Activity in Glycoside Hydrolase Family 31
Q27663896Structural Insight into the Mechanism of c-di-GMP Hydrolysis by EAL Domain Phosphodiesterases
Q27677517Structural Insights into Antibody Sequestering and Neutralizing of Na + Channel α-Type Modulator from Old World Scorpion Venom
Q27684887Structural Insights into the Catalytic Mechanism of Synechocystis Magnesium Protoporphyrin IX O -Methyltransferase (ChlM)
Q27678069Structural Insights into the Ferroxidase Site of Ferritins from Higher Eukaryotes
Q27665838Structural Underpinnings of Nitrogen Regulation by the Prototypical Nitrogen-Responsive Transcriptional Factor NrpR
Q27643481Structural analysis of Xanthomonas XopD provides insights into substrate specificity of ubiquitin-like protein proteases
Q51596676Structural analysis of a function-associated loop mutant of the substrate-recognition domain of Fbs1 ubiquitin ligase.
Q27667916Structural analysis of a putative aminoglycoside N-acetyltransferase from Bacillus anthracis
Q27667570Structural analysis of a putative family 32 carbohydrate-binding module from theStreptococcus pneumoniaeenzyme EndoD
Q36438036Structural analysis of haemoglobin binding by HpuA from the Neisseriaceae family
Q27641814Structural analysis of lipid complexes of GM2-activator protein
Q24304211Structural analysis of the synaptic protein neuroligin and its beta-neurexin complex: determinants for folding and cell adhesion
Q24536893Structural analysis of two enzymes catalysing reverse metabolic reactions implies common ancestry
Q27653616Structural analysis reveals DNA binding properties of Rv2827c, a hypothetical protein from Mycobacterium tuberculosis
Q27648150Structural and Biochemical Basis for Polyamine Binding to the Tp0655 Lipoprotein of Treponema pallidum: Putative Role for Tp0655 (TpPotD) as a Polyamine Receptor
Q27681147Structural and Biochemical Basis for Ubiquitin Ligase Recruitment by Arrestin-related Domain-containing Protein-3 (ARRDC3)
Q27664447Structural and Biochemical Studies of a Fluoroacetyl-CoA-Specific Thioesterase Reveal a Molecular Basis for Fluorine Selectivity
Q27654814Structural and Biophysical Characterization of BoxC from Burkholderia xenovorans LB400: A NOVEL RING-CLEAVING ENZYME IN THE CROTONASE SUPERFAMILY
Q27673793Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human KDM4 Histone Demethylase Family
Q27655362Structural and Functional Analysis of the Globular Head Domain of p115 Provides Insight into Membrane Tethering
Q27655359Structural and Functional Characterisation of a Conserved Archaeal RadA Paralog with Antirecombinase Activity
Q27678618Structural and Functional Characterization of Microcin C Resistance Peptidase MccF from Bacillus anthracis
Q27659892Structural and Functional Characterization of SporoSAG: A SAG2-RELATED SURFACE ANTIGEN FROM TOXOPLASMA GONDII
Q36193159Structural and Functional Characterization of the Hazelnut Allergen Cor a 8
Q27670716Structural and Functional Insights into DR2231 Protein, the MazG-like Nucleoside Triphosphate Pyrophosphohydrolase from Deinococcus radiodurans
Q27670941Structural and Functional Profiling of the Human Histone Methyltransferase SMYD3
Q57091000Structural and Mutational Analysis of Substrate Complexation by Anthranilate Phosphoribosyltransferase fromSulfolobus solfataricus
Q24305176Structural and biochemical analysis reveal pirins to possess quercetinase activity
Q30042256Structural and biochemical characterization of a mitochondrial peroxiredoxin from Plasmodium falciparum
Q36393196Structural and biochemical characterization of a novel Mn2+-dependent phosphodiesterase encoded by the yfcE gene.
Q27671188Structural and biochemical characterization of a trapped coenzyme A adduct ofCaenorhabditis elegansglucosamine-6-phosphateN-acetyltransferase 1
Q28289498Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases
Q45197483Structural and biochemical evidence for an enzymatic quinone redox cycle in Escherichia coli: identification of a novel quinol monooxygenase
Q34579798Structural and biochemical studies of the C-terminal domain of mouse peptide-N-glycanase identify it as a mannose-binding module
Q27679787Structural and bioinformatic analysis of the kiwifruit allergen Act d 11, a member of the family of ripening-related proteins
Q46096490Structural and chemical requirements for histidine phosphorylation by the chemotaxis kinase CheA.
Q27667082Structural and enzymatic characterization of a glycoside hydrolase family 31 α-xylosidase from Cellvibrio japonicus involved in xyloglucan saccharification
Q27689442Structural and functional analyses of a glutaminyl cyclase from Ixodes scapularis reveal metal-independent catalysis and inhibitor binding
Q24529594Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferase
Q24642435Structural and functional analysis of SmeT, the repressor of the Stenotrophomonas maltophilia multidrug efflux pump SmeDEF
Q27639783Structural and functional analysis of the kid toxin protein from E. coli plasmid R1
Q27657606Structural and functional characteristics of xenavidin, the first frog avidin from Xenopus tropicalis
Q27644542Structural and functional characterization of a novel T cell receptor co-regulatory protein complex, CD97-CD55
Q24633112Structural and functional characterization of a novel homodimeric three-finger neurotoxin from the venom of Ophiophagus hannah (king cobra)
Q27655625Structural and functional characterization of a putative polysaccharide deacetylase of the human parasiteEncephalitozoon cuniculi
Q27640170Structural and functional characterization of the Pseudomonas hydroperoxide resistance protein Ohr.
Q38014319Structural and functional dissection of aminocoumarin antibiotic biosynthesis: a review
Q27642598Structural and functional features of theEscherichia colihydroperoxide resistance protein OsmC
Q27673218Structural and functional insight into the mechanism of an alkaline exonuclease from Laribacter hongkongensis
Q27678522Structural and functional insight into the universal stress protein family
Q33993041Structural and functional studies suggest a catalytic mechanism for the phosphotransacetylase from Methanosarcina thermophila
Q24645419Structural and mechanistic insight into the basis of mucopolysaccharidosis IIIB
Q27689132Structural and mechanistic insights into an extracytoplasmic copper trafficking pathway in Streptomyces lividans
Q24321241Structural and mechanistic studies on the inhibition of the hypoxia-inducible transcription factor hydroxylases by tricarboxylic acid cycle intermediates
Q27646147Structural and membrane binding analysis of the Phox homology domain of Bem1p: basis of phosphatidylinositol 4-phosphate specificity
Q50091770Structural and mutational analysis of human Ad37 and canine adenovirus 2 fiber heads in complex with the D1 domain of coxsackie and adenovirus receptor.
Q27633990Structural and mutational analysis of the PhoQ histidine kinase catalytic domain. Insight into the reaction mechanism
Q34392501Structural and mutational analysis of the SBDS protein family. Insight into the leukemia-associated Shwachman-Diamond Syndrome
Q27644220Structural and mutational studies of anthocyanin malonyltransferases establish the features of BAHD enzyme catalysis
Q27650045Structural and thermodynamic analyses of solute-binding Protein from Bifidobacterium longum specific for core 1 disaccharide and lacto-N-biose I
Q27641395Structural and thermodynamic dissection of specific mannan recognition by a carbohydrate binding module, TmCBM27
Q42634227Structural and transcriptional analyses of a purine nucleotide-binding protein from Pyrococcus furiosus: a component of a novel, membrane-bound multiprotein complex unique to this hyperthermophilic archaeon
Q27639595Structural basis for AMPA receptor activation and ligand selectivity: crystal structures of five agonist complexes with the GluR2 ligand-binding core
Q24299379Structural basis for ARF1-mediated recruitment of ARHGAP21 to Golgi membranes
Q24298505Structural basis for Arl1-dependent targeting of homodimeric GRIP domains to the Golgi apparatus
Q54040210Structural basis for HIV-1 neutralization by a gp41 fusion intermediate-directed antibody.
Q24563113Structural basis for L27 domain-mediated assembly of signaling and cell polarity complexes
Q27635419Structural basis for Ni(2+) transport and assembly of the urease active site by the metallochaperone UreE from Bacillus pasteurii
Q27641338Structural basis for SH3 domain-mediated high-affinity binding between Mona/Gads and SLP-76
Q43192506Structural basis for UTP specificity of RNA editing TUTases from Trypanosoma brucei
Q27644319Structural basis for autoinhibition of Notch
Q27644284Structural basis for enzymatic excision of N1-methyladenine and N3-methylcytosine from DNA
Q27653005Structural basis for gibberellin recognition by its receptor GID1
Q41785648Structural basis for haem piracy from host haemopexin by Haemophilus influenzae.
Q27657254Structural basis for ligand and substrate recognition by torovirus hemagglutinin esterases.
Q35025071Structural basis for ligand promiscuity in cytochrome P450 3A4.
Q24307771Structural basis for mammalian vitamin B12 transport by transcobalamin
Q28302835Structural basis for metal ion coordination and the catalytic mechanism of sphingomyelinases D
Q27628860Structural basis for nucleotide exchange and competition with tRNA in the yeast elongation factor complex eEF1A:eEF1Balpha
Q24336970Structural basis for polyproline recognition by the FE65 WW domain
Q27677073Structural basis for recognition of H3K56-acetylated histone H3–H4 by the chaperone Rtt106
Q27646871Structural basis for recognition of breast and colon cancer epitopes Tn antigen and Forssman disaccharide by Helix pomatia lectin
Q24672052Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27
Q24306152Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide
Q54492936Structural basis for substrate binding, cleavage and allostery in the tRNA maturase RNase Z.
Q24652968Structural basis for substrate fatty acyl chain specificity: crystal structure of human very-long-chain acyl-CoA dehydrogenase
Q27650819Structural basis for substrate recognition and hydrolysis by mouse carnosinase CN2
Q27646754Structural basis for synthesis of inflammatory mediators by human leukotriene C4 synthase
Q24642648Structural basis for the NAD-hydrolysis mechanism and the ARTT-loop plasticity of C3 exoenzymes
Q27932010Structural basis for the assembly of a nuclear export complex.
Q45016651Structural basis for the binding of compatible solutes by ProX from the hyperthermophilic archaeon Archaeoglobus fulgidus.
Q27646469Structural basis for the function of DCN-1 in protein Neddylation
Q28570360Structural basis for the inhibitory role of tomosyn in exocytosis
Q38328871Structural basis for the interaction between human milk oligosaccharides and the bacterial lectin PA-IIL of Pseudomonas aeruginosa
Q36764971Structural basis for the membrane association of ankyrinG via palmitoylation
Q42547293Structural basis for the recognition of guide RNA and target DNA heteroduplex by Argonaute
Q34536831Structural basis for the redox control of plant glutamate cysteine ligase.
Q50736444Structural basis for the spectral difference in luciferase bioluminescence.
Q27671700Structural basis for the substrate recognition and catalysis of peptidyl-tRNA hydrolase
Q30160822Structural basis of 5-nitroimidazole antibiotic resistance: the crystal structure of NimA from Deinococcus radiodurans.
Q27651729Structural basis of Clostridium perfringens toxin complex formation
Q27647566Structural basis of Dscam isoform specificity
Q27659390Structural basis of YAP recognition by TEAD4 in the Hippo pathway
Q27643631Structural basis of allele variation of human thiopurine-S-methyltransferase
Q27642656Structural basis of calcium and galactose recognition by the lectin PA-IL of Pseudomonas aeruginosa
Q27346512Structural basis of cytotoxicity mediated by the type III secretion toxin ExoU from Pseudomonas aeruginosa
Q42747768Structural basis of fumarate hydratase deficiency
Q27650340Structural basis of proteolytic activation of L-phenylalanine oxidase from Pseudomonas sp. P-501
Q34511593Structural basis of reduction-dependent activation of human cystatin F.
Q24301370Structural basis of semaphorin-plexin signalling
Q27646887Structural basis of substrate-binding specificity of human arylamine N-acetyltransferases
Q38344257Structural basis of sugar-recognizing ubiquitin ligase
Q35794344Structural basis of the 3'-end recognition of a leading strand in stalled replication forks by PriA.
Q27644606Structural basis of the catalytic reaction mechanism of novel 1,2-alpha-L-fucosidase from Bifidobacterium bifidum
Q42132567Structural basis of the interaction between the putative adhesion-involved and iron-regulated FrpD and FrpC proteins of Neisseria meningitidis
Q24317769Structural basis of the migfilin-filamin interaction and competition with integrin beta tails
Q55113662Structural biology computing: Lessons for the biomedical research sciences
Q28489540Structural characterization and function determination of a nonspecific carboxylate esterase from the amidohydrolase superfamily with a promiscuous ability to hydrolyze methylphosphonate esters
Q27660309Structural characterization of Burkholderia pseudomallei adenylate kinase (Adk): Profound asymmetry in the crystal structure of the ‘open’ state
Q27667100Structural characterization of CalO1: a putative orsellinic acid methyltransferase in the calicheamicin-biosynthetic pathway
Q36458407Structural characterization of GntR/HutC family signaling domain
Q27676928Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members
Q36352176Structural characterization of core-bradavidin in complex with biotin
Q27665571Structural characterization of human S100A16, a low-affinity calcium binder
Q34996814Structural characterization of the Boca/Mesd maturation factors for LDL-receptor-type β propeller domains
Q27668151Structural characterization of the PPIase domain of FKBP51, a cochaperone of human Hsp90
Q27667659Structural characterization of the mitomycin 7-O-methyltransferase
Q30303111Structural characterization of the putative ABC-type 2 transporter from Thermotoga maritima MSB8.
Q27650281Structural complexes of human adenine phosphoribosyltransferase reveal novel features of the APRT catalytic mechanism
Q27643663Structural conservation of RecF and Rad50: implications for DNA recognition and RecF function
Q28119195Structural definition of the F-actin-binding THATCH domain from HIP1R
Q27657109Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptor
Q27635230Structural determinants for ligand binding and catalysis of triosephosphate isomerase
Q33922976Structural determinants of agonist-specific kinetics at the ionotropic glutamate receptor 2.
Q30477201Structural determinants of selective alpha-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP.
Q38313846Structural dissection of the reaction mechanism of cellobiose phosphorylase
Q27681061Structural dynamics of the aminoacylation and proofreading functional cycle of bacterial leucyl-tRNA synthetase
Q27645060Structural elucidation of the m157 mouse cytomegalovirus ligand for Ly49 natural killer cell receptors
Q24535595Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline
Q27638461Structural genomics: A pipeline for providing structures for the biologist
Q40775999Structural inhibition of the colicin D tRNase by the tRNA-mimicking immunity protein
Q24619681Structural insight into KCNQ (Kv7) channel assembly and channelopathy
Q25257757Structural insight into gene transcriptional regulation and effector binding by the Lrp/AsnC family.
Q27682067Structural insight into how Pseudomonas aeruginosa peptidoglycanhydrolase Tse1 and its immunity protein Tsi1 function
Q34324879Structural insight into poly(A) binding and catalytic mechanism of human PARN.
Q27671523Structural insight into the low affinity between Thermotoga maritima CheA and CheB compared to their Escherichia coli/Salmonella typhimurium counterparts
Q27650112Structural insight into the mechanism of substrate specificity and catalytic activity of an HD-domain phosphohydrolase: the 5'-deoxyribonucleotidase YfbR from Escherichia coli
Q99571780Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases
Q28116050Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly
Q27653016Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1
Q27652083Structural insights into amino acid binding and gene control by a lysine riboswitch
Q27933318Structural insights into endosomal sorting complex required for transport (ESCRT-I) recognition of ubiquitinated proteins.
Q27694598Structural insights into enzymatic degradation of oxidized polyvinyl alcohol
Q24308894Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP
Q24305108Structural insights into recognition of acetylated histone ligands by the BRPF1 bromodomain
Q27642734Structural insights into substrate specificity and function of glucodextranase
Q27649556Structural insights into the dual activity of RNase J
Q28769998Structural insights into the first incision reaction during nucleotide excision repair
Q27670621Structural insights into the function of 23S rRNA methyltransferase RlmG (m2G1835) from Escherichia coli
Q27652978Structural insights into the inhibited states of the Mer receptor tyrosine kinase
Q34502637Structural insights into the mechanism and inhibition of eukaryotic O-GlcNAc hydrolysis
Q24338433Structural insights into the recognition of substrates and activators by the OSR1 kinase
Q98463635Structural insights of the enzymes from the chitin utilization locus of Flavobacterium johnsoniae
Q28909148Structural mechanics of the pH-dependent activity of beta-carbonic anhydrase from Mycobacterium tuberculosis
Q24312868Structural ramification for acetyl-lysine recognition by the bromodomain of human BRG1 protein, a central ATPase of the SWI/SNF remodeling complex
Q38309351Structural rearrangements of sucrose phosphorylase from Bifidobacterium adolescentis during sucrose conversion.
Q27635893Structural requirements of endopolygalacturonase for the interaction with PGIP (polygalacturonase-inhibiting protein)
Q27647006Structural similarity between the DnaA-binding proteins HobA (HP1230) from Helicobacter pylori and DiaA from Escherichia coli
Q24312741Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A
Q28263057Structural snapshots of Escherichia coli histidinol phosphate phosphatase along the reaction pathway
Q34438336Structural studies of cinnamoyl-CoA reductase and cinnamyl-alcohol dehydrogenase, key enzymes of monolignol biosynthesis.
Q36458499Structural studies of human alkaline phosphatase in complex with strontium: implication for its secondary effect in bones
Q27640444Structural studies of molybdopterin synthase provide insights into its catalytic mechanism
Q27642884Structural studies on flavin reductase PheA2 reveal binding of NAD in an unusual folded conformation and support novel mechanism of action
Q27664980Structural studies on the enzyme complex isopropylmalate isomerase (LeuCD) from Mycobacterium tuberculosis
Q35516038Structural variation in bacterial glyoxalase I enzymes: investigation of the metalloenzyme glyoxalase I from Clostridium acetobutylicum.
Q27659058Structure Function Studies of Vaccinia Virus Host Range Protein K1 Reveal a Novel Functional Surface for Ankyrin Repeat Proteins
Q27683687Structure analysis of the global metabolic regulator Crc from Pseudomonas aeruginosa
Q27660959Structure and Activity of the Metal-independent Fructose-1,6-bisphosphatase YK23 from Saccharomyces cerevisiae
Q27664369Structure and Cellular Roles of the RMI Core Complex from the Bloom Syndrome Dissolvasome
Q27659630Structure and DNA binding activity of the mouse condensin hinge domain highlight common and diverse features of SMC proteins
Q40018615Structure and DNA-binding properties of the cytolysin regulator CylR2 from Enterococcus faecalis
Q27640844Structure and Dynamics of UDP–Glucose Pyrophosphorylase from Arabidopsis thaliana with Bound UDP–Glucose and UTP
Q24337331Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b
Q27649568Structure and Function of A41, a Vaccinia Virus Chemokine Binding Protein
Q27642280Structure and Interactions of NCAM Ig1-2-3 Suggest a Novel Zipper Mechanism for Homophilic Adhesion
Q27670570Structure and Mechanism of the trans -Acting Acyltransferase from the Disorazole Synthase
Q27660353Structure and Protein-Protein Interaction Studies on Chlamydia trachomatis Protein CT670 (YscO Homolog)
Q27652822Structure and Substrate Recruitment of the Human Spindle Checkpoint Kinase Bub1
Q46594066Structure and activity of the atypical serine kinase Rio1.
Q46907790Structure and activity of two metal ion-dependent acetylxylan esterases involved in plant cell wall degradation reveals a close similarity to peptidoglycan deacetylases.
Q27657237Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1
Q27628611Structure and assembly of the Alu domain of the mammalian signal recognition particle
Q38340908Structure and assembly of the RNA binding domain of bluetongue virus non-structural protein 2.
Q27649369Structure and catalytic mechanism of eukaryotic selenocysteine synthase
Q27644002Structure and characterization of a novel chicken biotin-binding protein A (BBP-A)
Q27677375Structure and function of CYP108D1 from Novosphingobium aromaticivorans DSM12444: an aromatic hydrocarbon-binding P450 enzyme
Q42043296Structure and function of GDP-mannose-3',5'-epimerase: an enzyme which performs three chemical reactions at the same active site
Q27937176Structure and function of Tim14 and Tim16, the J and J-like components of the mitochondrial protein import motor
Q27640539Structure and function of an archaeal homolog of survival protein E (SurEalpha): an acid phosphatase with purine nucleotide specificity
Q24596697Structure and function of both domains of ArnA, a dual function decarboxylase and a formyltransferase, involved in 4-amino-4-deoxy-L-arabinose biosynthesis
Q45100697Structure and function of the C-terminal domain of the polymerase cofactor of rabies virus
Q24681912Structure and interactions of the first three RNA recognition motifs of splicing factor prp24
Q45310569Structure and kinetics of a monomeric glucosamine 6-phosphate deaminase: missing link of the NagB superfamily?
Q27640692Structure and ligand binding of carbohydrate-binding module CsCBM6-3 reveals similarities with fucose-specific lectins and "galactose-binding" domains
Q27937235Structure and mechanism of ADP-ribose-1''-monophosphatase (Appr-1''-pase), a ubiquitous cellular processing enzyme
Q28492135Structure and mechanism of a bacterial beta-glucosaminidase having O-GlcNAcase activity
Q27631738Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme
Q27649111Structure and metal binding properties of ZnuA, a periplasmic zinc transporter from Escherichia coli
Q27650001Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms
Q34077718Structure and metal-dependent mechanism of peptidoglycan deacetylase, a streptococcal virulence factor
Q27653012Structure and non-essential function of glycerol kinase inPlasmodium falciparumblood stages
Q24656034Structure and proposed activity of a member of the VapBC family of toxin-antitoxin systems. VapBC-5 from Mycobacterium tuberculosis
Q37657138Structure and protective efficacy of the Staphylococcus aureus autocleaving protease EpiP.
Q27640961Structure and quantum chemical characterization of chloroperoxidase compound 0, a common reaction intermediate of diverse heme enzymes
Q24312927Structure and reactivity of human mitochondrial 2,4-dienoyl-CoA reductase: enzyme-ligand interactions in a distinctive short-chain reductase active site
Q34043647Structure and reactivity of hydroxypropylphosphonic acid epoxidase in fosfomycin biosynthesis by a cation- and flavin-dependent mechanism.
Q27687046Structure and secretion of CofJ, a putative colonization factor of enterotoxigenic Escherichia coli
Q35951121Structure at 1.6 A resolution of the protein from gene locus At3g22680 from Arabidopsis thaliana
Q28492891Structure determination of an FMN reductase from Pseudomonas aeruginosa PA01 using sulfur anomalous signal
Q27638950Structure of 2C-methyl-D-erythritol 2,4- cyclodiphosphate synthase: an essential enzyme for isoprenoid biosynthesis and target for antimicrobial drug development
Q27643942Structure of 5-formyltetrahydrofolate cyclo-ligase fromBacillus anthracis(BA4489)
Q36870144Structure of Arabidopsis thaliana At1g77540 protein, a minimal acetyltransferase from the COG2388 family.
Q24657871Structure of Bacillus subtilis YXKO--a member of the UPF0031 family and a putative kinase
Q27679001Structure of Bradavidin – C-Terminal Residues Act as Intrinsic Ligands
Q27675239Structure of Collagen Receptor Integrin  1I Domain Carrying the Activating Mutation E317A
Q27675073Structure of Escherichia coli RutC, a member of the YjgF family and putative aminoacrylate peracid reductase of the rut operon
Q27657272Structure of EstA esterase from psychrotrophicPseudoalteromonassp. 643A covalently inhibited by monoethylphosphonate
Q28485426Structure of FliM provides insight into assembly of the switch complex in the bacterial flagella motor
Q27675646Structure of Gentlyase, the neutral metalloprotease ofPaenibacillus polymyxa
Q27631571Structure of Hjc, a Holliday junction resolvase, from Sulfolobus solfataricus
Q27667266Structure of HsdS Subunit from Thermoanaerobacter tengcongensis Sheds Lights on Mechanism of Dynamic Opening and Closing of Type I Methyltransferase
Q27652487Structure of L-Xylulose-5-Phosphate 3-Epimerase (UlaE) from the Anaerobic L-Ascorbate Utilization Pathway of Escherichia coli: Identification of a Novel Phosphate Binding Motif within a TIM Barrel Fold
Q27619169Structure of L-aspartate oxidase: implications for the succinate dehydrogenase/fumarate reductase oxidoreductase family
Q42411750Structure of Mesorhizobium loti arylamine N-acetyltransferase 1.
Q35950620Structure of PIN-domain protein PH0500 from Pyrococcus horikoshii
Q81330900Structure of Ptr ToxA: an RGD-containing host-selective toxin from Pyrenophora tritici-repentis
Q27650908Structure of SO2946 orphan from Shewanella oneidensis shows “jelly-roll” fold with carbohydrate-binding module
Q27652003Structure of Staphylococcus aureus EsxA Suggests a Contribution to Virulence by Action as a Transport Chaperone and/or Adaptor Protein
Q27622332Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine
Q24642964Structure of Thermotoga maritima stationary phase survival protein SurE: a novel acid phosphatase
Q27649357Structure of Vps26B and mapping of its interaction with the retromer protein complex
Q30435859Structure of YidB protein from Shigella flexneri shows a new fold with homeodomain motif
Q27658888Structure of YqgQ protein fromBacillus subtilis, a conserved hypothetical protein
Q27640350Structure of a Drosophila sigma class glutathione S-transferase reveals a novel active site topography suited for lipid peroxidation products
Q46886569Structure of a [2Fe-2S] ferredoxin from Rhodobacter capsulatus likely involved in Fe-S cluster biogenesis and conformational changes observed upon reduction.
Q27685171Structure of a bacterial glycoside hydrolase family 63 enzyme in complex with its glycosynthase product, and insights into the substrate specificity
Q27639269Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA
Q24554202Structure of a cholesterol-binding protein deficient in Niemann-Pick type C2 disease
Q27640913Structure of a conserved hypothetical protein SA1388 from S. aureus reveals a capped hexameric toroid with two PII domain lids and a dinuclear metal center
Q27635340Structure of a family 15 carbohydrate-binding module in complex with xylopentaose. Evidence that xylan binds in an approximate 3-fold helical conformation
Q43257652Structure of a flavonoid glucosyltransferase reveals the basis for plant natural product modification
Q27638084Structure of a functional IGF2R fragment determined from the anomalous scattering of sulfur
Q34201820Structure of a group A streptococcal phage-encoded virulence factor reveals a catalytically active triple-stranded beta-helix
Q43018765Structure of a halophilic nucleoside diphosphate kinase from Halobacterium salinarum.
Q45696228Structure of a knockout mutant of influenza virus M1 protein that has altered activities in membrane binding, oligomerisation and binding to NEP (NS2).
Q34161099Structure of a nonheme globin in environmental stress signaling.
Q27675306Structure of a periplasmic glucose-binding protein fromThermotoga maritima
Q27660223Structure of a polyisoprenoid binding domain from Saccharophagus degradans implicated in plant cell wall breakdown
Q27681676Structure of a post-translationally processed heterodimeric double-headed Kunitz-type serine protease inhibitor from potato
Q33581892Structure of a proteolytically resistant core from the severe acute respiratory syndrome coronavirus S2 fusion protein
Q27646669Structure of a putative β-phosphoglucomutase (TM1254) fromThermotoga maritima
Q27681078Structure of a short-chain dehydrogenase/reductase from Bacillus anthracis
Q27682341Structure of a thermophilic cyanobacterial b6f-type Rieske protein
Q27622631Structure of a two-domain chitotriosidase from Serratia marcescens at 1.9-A resolution
Q27648371Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH
Q27650250Structure of acostatin, a dimeric disintegrin from Southern copperhead (Agkistrodon contortrix contortrix), at 1.7 Å resolution
Q35037226Structure of aminopeptidase N from Escherichia coli suggests a compartmentalized, gated active site
Q27658251Structure of an N-terminally truncated Nudix hydrolase DR2204 fromDeinococcus radiodurans
Q27679310Structure of an early native-like intermediate of β2-microglobulin amyloidogenesis
Q27638916Structure of apo-phosphatidylinositol transfer protein alpha provides insight into membrane association.
Q36426310Structure of armadillo ACBP: a new member of the acyl-CoA-binding protein family.
Q27639468Structure of arterivirus nsp4. The smallest chymotrypsin-like proteinase with an alpha/beta C-terminal extension and alternate conformations of the oxyanion hole
Q27640995Structure of aspartoacylase, the brain enzyme impaired in Canavan disease
Q27649813Structure of calcium-bound human S100A13 at pH 7.5 at 1.8 Å resolution
Q24543850Structure of complement factor H carboxyl-terminus reveals molecular basis of atypical haemolytic uremic syndrome
Q27650821Structure of coronavirus hemagglutinin-esterase offers insight into corona and influenza virus evolution
Q24613075Structure of cyanase reveals that a novel dimeric and decameric arrangement of subunits is required for formation of the enzyme active site
Q46384097Structure of human cyclophilin A in complex with the novel immunosuppressant sanglifehrin A at 1.6 A resolution
Q24305246Structure of human dCK suggests strategies to improve anticancer and antiviral therapy
Q27649765Structure of human dual specificity protein phosphatase 23, VHZ, enzyme-substrate/product complex
Q27646652Structure of hypothetical Mo-cofactor biosynthesis protein B (ST2315) fromSulfolobus tokodaii
Q27679826Structure of isochorismate synthase DhbC from Bacillus anthracis
Q24598268Structure of melanoma inhibitory activity protein, a member of a recently identified family of secreted proteins
Q27639479Structure of mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 suggests a bifunctional switch that couples kinase activation with nuclear export
Q38342137Structure of mouse Golgi alpha-mannosidase IA reveals the molecular basis for substrate specificity among class 1 (family 47 glycosylhydrolase) alpha1,2-mannosidases
Q24555822Structure of palmitoylated BET3: insights into TRAPP complex assembly and membrane localization
Q27639228Structure of porphobilinogen synthase from Pseudomonas aeruginosa in complex with 5-fluorolevulinic acid suggests a double Schiff base mechanism
Q50735699Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning.
Q27643740Structure of rat acidic fibroblast growth factor at 1.4 Å resolution
Q35843917Structure of testis ACE glycosylation mutants and evidence for conserved domain movement
Q27667121Structure of the C-terminal domain of Saccharomyces cerevisiae Nup133, a component of the nuclear pore complex
Q27656624Structure of the C-terminal domain of nsp4 from feline coronavirus
Q27651601Structure of the C-terminal domain of the arginine repressor protein fromMycobacterium tuberculosis
Q27643639Structure of the C-terminal half of UvrC reveals an RNase H endonuclease domain with an Argonaute-like catalytic triad
Q27683946Structure of the C-terminal half of human XPB helicase and the impact of the disease-causing mutation XP11BE
Q27650881Structure of the C-terminal head domain of the fowl adenovirus type 1 short fibre
Q27650710Structure of the DNA Repair Helicase XPD
Q27659060Structure of the Dimerization Domain of the Rabies Virus Phosphoprotein
Q27664879Structure of the Dom34-Hbs1 complex and implications for no-go decay
Q24536732Structure of the EMAPII domain of human aminoacyl-tRNA synthetase complex reveals evolutionary dimer mimicry
Q40567830Structure of the Essential Mtb FadD32 Enzyme: A Promising Drug Target for Treating Tuberculosis
Q27680306Structure of the Homodimeric Glycine Decarboxylase P-protein from Synechocystis sp. PCC 6803 Suggests a Mechanism for Redox Regulation
Q27649717Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans
Q27485162Structure of the Murray Valley encephalitis virus RNA helicase at 1.9 Å resolution
Q24337012Structure of the N-terminal domain of the FOP (FGFR1OP) protein and implications for its dimerization and centrosomal localization
Q27670584Structure of the RBD-PRDI fragment of the antiterminator protein GlcT
Q27649733Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase
Q27649311Structure of the Receptor-Binding Protein of Bacteriophage Det7: a Podoviral Tail Spike in a Myovirus
Q35994898Structure of the SARS coronavirus main proteinase as an active C2 crystallographic dimer
Q27652850Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases
Q27704894Structure of the T4 baseplate and its function in triggering sheath contraction
Q27655698Structure of the Ternary Complex of Phosphomevalonate Kinase: The Enzyme and Its Family
Q27646601Structure of the ThDP-dependent enzyme benzaldehyde lyase refined to 1.65 Å resolution
Q27658250Structure of the adenylation domain of NAD+-dependent DNA ligase fromStaphylococcus aureus
Q27638714Structure of the bacterial RNA polymerase promoter specificity sigma subunit
Q50095688Structure of the bacterial flagellar hook and implication for the molecular universal joint mechanism.
Q27644311Structure of the buffalo secretory signalling glycoprotein at 2.8 Å resolution
Q27678521Structure of the c10 ring of the yeast mitochondrial ATP synthase in the open conformation
Q27677381Structure of the catalytic domain of the Clostridium thermocellum cellulase CelT
Q27675137Structure of the catalytic domain of theSalmonellavirulence factor SseI
Q27642799Structure of the catalytic fragment of translation initiation factor 2B and identification of a critically important catalytic residue
Q33339927Structure of the conserved domain of ANAC, a member of the NAC family of transcription factors
Q27682999Structure of the corrinoid:coenzyme M methyltransferase MtaA from Methanosarcina mazei
Q27661993Structure of the dimerization domain of DiGeorge Critical Region 8
Q24648836Structure of the fungal beta-glucan-binding immune receptor dectin-1: implications for function
Q34394266Structure of the house dust mite allergen Der f 2: implications for function and molecular basis of IgE cross-reactivity
Q27655343Structure of the human Nac1 POZ domain
Q27641290Structure of the human beta-ketoacyl [ACP] synthase from the mitochondrial type II fatty acid synthase
Q45216896Structure of the major cytosolic glutathione S-transferase from the parasitic nematode Onchocerca volvulus
Q27663868Structure of the micronemal protein 2 A/I domain fromToxoplasma gondii
Q27628828Structure of the molecular chaperone prefoldin: unique interaction of multiple coiled coil tentacles with unfolded proteins
Q27641194Structure of the monooxygenase component of a two-component flavoprotein monooxygenase
Q34497659Structure of the mouse peptide N-glycanase-HR23 complex suggests co-evolution of the endoplasmic reticulum-associated degradation and DNA repair pathways.
Q27690679Structure of the nisin leader peptidase NisP revealing a C-terminal autocleavage activity
Q36253498Structure of the nuclear exosome component Rrp6p reveals an interplay between the active site and the HRDC domain
Q35222255Structure of the origin-binding domain of simian virus 40 large T antigen bound to DNA.
Q30164179Structure of the polyketide cyclase SnoaL reveals a novel mechanism for enzymatic aldol condensation
Q27639150Structure of the retinal determination protein Dachshund reveals a DNA binding motif
Q27639902Structure of the sporulation-specific transcription factor Ndt80 bound to DNA.
Q27651590Structure of the thioredoxin-like domain of yeast glutaredoxin 3
Q34324896Structure of unliganded HSV gD reveals a mechanism for receptor-mediated activation of virus entry.
Q27659441Structure of uracil-DNAN-glycosylase (UNG) fromVibrio cholerae: mapping temperature adaptation through structural and mutational analysis
Q27654545Structure ofDebaryomyces castelliiCBS 2923 phytase
Q27650786Structure ofDeinococcus radioduranstunicamycin-resistance protein (TmrD), a phosphotransferase
Q27653403Structure, Binding, and Activity of Syd, a SecY-interacting Protein
Q27658572Structure, Mechanism, and Substrate Profile for Sco3058: The Closest Bacterial Homologue to Human Renal Dipeptidase,
Q24656225Structure- and function-based characterization of a new phosphoglycolate phosphatase from Thermoplasma acidophilum
Q40024861Structure-Based Insight into the Asymmetric Bioreduction of the C=C Double Bond of alpha,beta-Unsaturated Nitroalkenes by Pentaerythritol Tetranitrate Reductase
Q27666367Structure-Function Analyses of a Caffeic Acid O -Methyltransferase from Perennial Ryegrass Reveal the Molecular Basis for Substrate Preference
Q27653480Structure-Function Relationship of the Chloroplastic Glutaredoxin S12 with an Atypical WCSYS Active Site
Q27649337Structure-assisted discovery of an aminothiazole derivative as a lead molecule for inhibition of bacterial fatty-acid synthesis
Q30478835Structure-based engineering of internal cavities in coiled-coil peptides.
Q27935132Structure-based functional annotation: yeast ymr099c codes for a D-hexose-6-phosphate mutarotase
Q27687825Structure-based optimization of the terminal tripeptide in glycopeptide dendrimer inhibitors of Pseudomonas aeruginosa biofilms targeting LecA
Q27681054Structure-function studies of an unusual 3-methyladenine DNA glycosylase II (AlkA) from Deinococcus radiodurans
Q27675796Structure-guided studies of the SHP-1/JAK1 interaction provide new insights into phosphatase catalytic domain substrate recognition
Q27679818Structure/Function Analysis of a Type III Polyketide Synthase in the Brown Alga Ectocarpus siliculosus Reveals a Biochemical Pathway in Phlorotannin Monomer Biosynthesis
Q28274662Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations
Q24656690Structures of BIR domains from human NAIP and cIAP2
Q44976541Structures of Bacillus subtilis PdaA, a family 4 carbohydrate esterase, and a complex with N-acetyl-glucosamine
Q27672453Structures of Human DPP7 Reveal the Molecular Basis of Specific Inhibition and the Architectural Diversity of Proline-Specific Peptidases
Q27644014Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity
Q27659855Structures of PHR Domains from Mus musculus Phr1 (Mycbp2) Explain the Loss-of-Function Mutation (Gly1092→Glu) of the C. elegans Ortholog RPM-1
Q27644607Structures of Staphylococcus aureus D-tagatose-6-phosphate kinase implicate domain motions in specificity and mechanism
Q42688039Structures of apo- and holo-tyrosine phenol-lyase reveal a catalytically critical closed conformation and suggest a mechanism for activation by K+ ions
Q28273530Structures of complement component C3 provide insights into the function and evolution of immunity
Q27666299Structures of domains I and IV from YbbR are representative of a widely distributed protein family
Q27653389Structures of endonuclease V with DNA reveal initiation of deaminated adenine repair
Q24338927Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding
Q27640697Structures of shikimate dehydrogenase AroE and its Paralog YdiB. A common structural framework for different activities
Q27657361Structures of the Arm-type Binding Domains of HPI and HAI7 Integrases
Q36922797Structures of the N- and C-terminal domains of MHV-A59 nucleocapsid protein corroborate a conserved RNA-protein binding mechanism in coronavirus
Q27670796Structures of the PelD Cyclic Diguanylate Effector Involved in Pellicle Formation in Pseudomonas aeruginosa PAO1
Q27660306Structures of the autoproteolytic domain from theSaccharomyces cerevisiaenuclear pore complex component, Nup145
Q27640105Structures of the cancer-related Aurora-A, FAK, and EphA2 protein kinases from nanovolume crystallography
Q27938892Structures of the carbohydrate recognition domain of Ca2+-independent cargo receptors Emp46p and Emp47p
Q42643100Structures of the first and second double-stranded RNA-binding domains of human TAR RNA-binding protein
Q27653459Structures of the multicomponent Rieske non-heme iron toluene 2,3-dioxygenase enzyme system
Q27655318Structures of the tumor necrosis factor alpha inducing protein Tipalpha: a novel virulence factor from Helicobacter pylori
Q35167677Structures of three polycystic kidney disease-like domains from Clostridium histolyticum collagenases ColG and ColH.
Q27657920Structures of two truncated phage-tail hyaluronate lyases fromStreptococcus pyogenesserotype M1
Q27644749Studies on peptide:N-glycanase-p97 interaction suggest that p97 phosphorylation modulates endoplasmic reticulum-associated degradation
Q34796506Subfamily-specific adaptations in the structures of two penicillin-binding proteins from Mycobacterium tuberculosis
Q27633262Substrate flow in catalases deduced from the crystal structures of active site variants of HPII from Escherichia coli
Q40249260Substrate recognition and catalysis by the Holliday junction resolving enzyme Hje.
Q34323063Substrate-induced conformational changes in human UMP/CMP kinase
Q27642465Sulfur single-wavelength anomalous diffraction crystal structure of a pheromone-binding protein from the honeybee Apis mellifera L
Q90212036Super Potent Bispecific Llama VHH Antibodies Neutralize HIV via a Combination of gp41 and gp120 Epitopes
Q27702560Superoxide reductase from Giardia intestinalis: structural characterization of the first SOR from a eukaryotic organism shows an iron centre that is highly sensitive to photoreduction
Q42120285Superoxide reductase from the syphilis spirochete Treponema pallidum: crystallization and structure determination using soft X-rays
Q30497306SurR regulates hydrogen production in Pyrococcus furiosus by a sulfur-dependent redox switch.
Q36672509Surprises and pitfalls arising from (pseudo)symmetry
Q27659278Switching Catalysis from Hydrolysis to Perhydrolysis in Pseudomonas fluorescens Esterase ,
Q36399643T cell cross-reactivity and conformational changes during TCR engagement
Q38739200TAK1-binding protein 1 is a pseudophosphatase.
Q44706800TEXTAL system: artificial intelligence techniques for automated protein model building
Q40018790Tandem LIM domains provide synergistic binding in the LMO4:Ldb1 complex
Q27727739Targeted Disruption of the Interaction Between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes
Q48223029Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
Q73616502The 'fingerprint' that X-rays can leave on structures
Q27642190The 0.93Å Crystal Structure of Sphericase: A Calcium-loaded Serine Protease from Bacillus sphaericus
Q27639364The 1.1 A crystal structure of human TGF-beta type II receptor ligand binding domain
Q42656301The 1.3 A crystal structure of the flavoprotein YqjM reveals a novel class of Old Yellow Enzymes
Q27644564The 1.4-A crystal structure of the S. pombe Pop2p deadenylase subunit unveils the configuration of an active enzyme
Q27657075The 1.5-Å Structure of XplA-heme, an Unusual Cytochrome P450 Heme Domain That Catalyzes Reductive Biotransformation of Royal Demolition Explosive
Q27641515The 1.6 A resolution structure of Fe-superoxide dismutase from the thermophilic cyanobacterium Thermosynechococcus elongatus
Q27675932The 1.6 Å Crystal Structure of Pyranose Dehydrogenase from Agaricus meleagris Rationalizes Substrate Specificity and Reveals a Flavin Intermediate
Q24297511The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link
Q27639006The 109 residue nerve tissue minihemoglobin from Cerebratulus lacteus highlights striking structural plasticity of the alpha-helical globin fold
Q27622535The 2 Å crystal structure of leucyl-tRNA synthetase and its complex with a leucyl-adenylate analogue
Q27639925The 2-A crystal structure of 6-oxo camphor hydrolase. New structural diversity in the crotonase superfamily
Q36426459The 2.1 A structure of Aerococcus viridans L-lactate oxidase (LOX)
Q27654534The Active Site of a Carbohydrate Esterase Displays Divergent Catalytic and Noncatalytic Binding Functions
Q27676839The Architecture of EssB, an Integral Membrane Component of the Type VII Secretion System
Q38799873The Architecture of the Anbu Complex Reflects an Evolutionary Intermediate at the Origin of the Proteasome System
Q28267097The C-terminal basic tail of RhoG assists the guanine nucleotide exchange factor trio in binding to phospholipids
Q27643300The C2A-C2B linker defines the high affinity Ca(2+) binding mode of rabphilin-3A
Q27643851The Crystal Structure of Bacillus subtilis YycI Reveals a Common Fold for Two Members of an Unusual Class of Sensor Histidine Kinase Regulatory Proteins
Q27640972The DCX-domain tandems of doublecortin and doublecortin-like kinase
Q42069819The Diamond Light Source and the challenges ahead for structural biology: some informal remarks
Q27658262The Distal Pocket Histidine Residue in Horse Heart Myoglobin Directs the O -Binding Mode of Nitrite to the Heme Iron
Q27682054The EAGR box structure: a motif involved in mycoplasma motility
Q27677021The Gal3p transducer of the GAL regulon interacts with the Gal80p repressor in its ligand-induced closed conformation
Q27646805The Laminin 511/521 binding site on the Lutheran blood group glycoprotein is located at the flexible junction of Ig domains 2 and 3
Q35215523The PDB_REDO server for macromolecular structure model optimization
Q24306231The RUNX1 Runt domain at 1.25A resolution: a structural switch and specifically bound chloride ions modulate DNA binding
Q27641705The Staphostatin-staphopain complex: a forward binding inhibitor in complex with its target cysteine protease
Q37015481The Structural Biology Center 19ID undulator beamline: facility specifications and protein crystallographic results.
Q27675907The Structure and Enzymatic Properties of a Novel RNase II Family Enzyme from Deinococcus radiodurans
Q27649703The Structure of Clostridium perfringens NanI Sialidase and Its Catalytic Intermediates
Q27644460The Structure of Two N-Methyltransferases from the Caffeine Biosynthetic Pathway
Q27676803The Structure of a Streptomyces avermitilis  -L-Rhamnosidase Reveals a Novel Carbohydrate-binding Module CBM67 within the Six-domain Arrangement
Q27656866The Structure of the Dizinc Subclass B2 Metallo- -Lactamase CphA Reveals that the Second Inhibitory Zinc Ion Binds in the Histidine Site
Q27653414The Structure of the MAP2K MEK6 Reveals an Autoinhibitory Dimer
Q27676785The Vibrio cholerae Colonization Factor GbpA Possesses a Modular Structure that Governs Binding to Different Host Surfaces
Q27657840The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA
Q24605244The Yersinia adhesin YadA collagen-binding domain structure is a novel left-handed parallel beta-roll
Q27641457The active conformation of glutamate synthase and its binding to ferredoxin
Q27639661The active principle of garlic at atomic resolution
Q33755346The active site of O-acetylserine sulfhydrylase is the anchor point for bienzyme complex formation with serine acetyltransferase
Q27640780The alpha-glucuronidase, GlcA67A, of Cellvibrio japonicus utilizes the carboxylate and methyl groups of aldobiouronic acid as important substrate recognition determinants
Q57050584The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signaling
Q27635758The binding site of acetylcholine receptor as visualized in the X-Ray structure of a complex between alpha-bungarotoxin and a mimotope peptide
Q34511800The closed structure of presequence protease PreP forms a unique 10,000 Angstroms3 chamber for proteolysis
Q24295264The complex of Arl2-GTP and PDE delta: from structure to function
Q36426377The copper-containing amine oxidase from Arthrobacter globiformis: refinement at 1.55 and 2.20 A resolution in two crystal forms
Q27639726The cross-reactive calcium-binding pollen allergen, Phl p 7, reveals a novel dimer assembly
Q34585464The crystal structure and mutational binding analysis of the extracellular domain of the platelet-activating receptor CLEC-2.
Q46868128The crystal structure of (S)-3-O-geranylgeranylglyceryl phosphate synthase reveals an ancient fold for an ancient enzyme
Q27641963The crystal structure of 1-D-myo-inosityl 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) from Mycobacterium tuberculosis reveals a zinc hydrolase with a lactate dehydrogenase fold
Q27675391The crystal structure of AphB, a virulence gene activator from Vibrio cholerae, reveals residues that influence its response to oxygen and pH
Q27632199The crystal structure of E. coli pantothenate synthetase confirms it as a member of the cytidylyltransferase superfamily
Q34335181The crystal structure of Escherichia coli MoaB suggests a probable role in molybdenum cofactor synthesis
Q27634513The crystal structure of Escherichia coli MoeA and its relationship to the multifunctional protein gephyrin
Q27637139The crystal structure of Helicobacter pylori cysteine-rich protein B reveals a novel fold for a penicillin-binding protein
Q36458476The crystal structure of Mycobacterium tuberculosis adenylate kinase in complex with two molecules of ADP and Mg2+ supports an associative mechanism for phosphoryl transfer.
Q27638528The crystal structure of Mycobacterium tuberculosis alkylhydroperoxidase AhpD, a potential target for antitubercular drug design
Q27651332The crystal structure of Pyrococcus abyssi tRNA (uracil-54, C5)-methyltransferase provides insights into its tRNA specificity
Q34650612The crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, defines a third class of sulfatases
Q27635042The crystal structure of Sulfolobus solfataricus elongation factor 1alpha in complex with GDP reveals novel features in nucleotide binding and exchange
Q27641314The crystal structure of a cockroach pheromone-binding protein suggests a new ligand binding and release mechanism
Q27631567The crystal structure of a heptameric archaeal Sm protein: Implications for the eukaryotic snRNP core
Q53344894The crystal structure of a human PP2A phosphatase activator reveals a novel fold and highly conserved cleft implicated in protein-protein interactions.
Q36476600The crystal structure of a novel SAM-dependent methyltransferase PH1915 from Pyrococcus horikoshii
Q36571987The crystal structure of augmenter of liver regeneration: A mammalian FAD-dependent sulfhydryl oxidase
Q48071304The crystal structure of auracyanin A at 1.85 A resolution: the structures and functions of auracyanins A and B, two almost identical "blue" copper proteins, in the photosynthetic bacterium Chloroflexus aurantiacus
Q24646382The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases
Q37647499The crystal structure of filamentous hemagglutinin secretion domain and its implications for the two-partner secretion pathway
Q27642398The crystal structure of gankyrin, an oncoprotein found in complexes with cyclin-dependent kinase 4, a 19 S proteasomal ATPase regulator, and the tumor suppressors Rb and p53
Q45149894The crystal structure of guinea pig 11beta-hydroxysteroid dehydrogenase type 1 provides a model for enzyme-lipid bilayer interactions
Q54633864The crystal structure of hexamer RraA from Pseudomonas aeruginosa reveals six conserved protein-protein interaction sites.
Q27650272The crystal structure of human WD40 repeat-containing peptidylprolyl isomerase (PPWD1)
Q41948918The crystal structure of human dipeptidyl peptidase I (cathepsin C) in complex with the inhibitor Gly-Phe-CHN2.
Q27637732The crystal structure of human tyrosyl-DNA phosphodiesterase, Tdp1
Q46751737The crystal structure of mismatch-specific uracil-DNA glycosylase (MUG) from Deinococcus radiodurans reveals a novel catalytic residue and broad substrate specificity.
Q27644329The crystal structure of phenylpyruvate decarboxylase from Azospirillum brasilense at 1.5 A resolution. Implications for its catalytic and regulatory mechanism
Q27636531The crystal structure of spermidine synthase with a multisubstrate adduct inhibitor
Q27657496The crystal structure of the AF2331 protein from Archaeoglobus fulgidus DSM 4304 forms an unusual interdigitated dimer with a new type of alpha + beta fold.
Q27642364The crystal structure of the Calystegia sepium agglutinin reveals a novel quaternary arrangement of lectin subunits with a beta-prism fold
Q27626968The crystal structure of the Escherichia coli MobA protein provides insight into molybdopterin guanine dinucleotide biosynthesis
Q27641638The crystal structure of the Escherichia coli YfdW gene product reveals a new fold of two interlaced rings identifying a wide family of CoA transferases
Q28252681The crystal structure of the Escherichia coli lipocalin Blc suggests a possible role in phospholipid binding
Q28486991The crystal structure of the Mycobacterium tuberculosis Rv3019c-Rv3020c ESX complex reveals a domain-swapped heterotetramer
Q24291846The crystal structure of the PX domain from p40(phox) bound to phosphatidylinositol 3-phosphate
Q27652454The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase
Q27647399The crystal structure of the effector-binding domain of the trehalose repressor TreR from Bacillus subtilis 168 reveals a unique quarternary assembly
Q24300447The crystal structure of the exon junction complex reveals how it maintains a stable grip on mRNA
Q24309182The crystal structure of the human Mov34 MPN domain reveals a metal-free dimer
Q27650046The crystal structure of the human toll-like receptor 10 cytoplasmic domain reveals a putative signaling dimer
Q27640175The crystal structure of the phosphorylation domain in PhoP reveals a functional tandem association mediated by an asymmetric interface
Q30418692The crystal structure of the reduced, Zn2+-bound form of the B. subtilis Hsp33 chaperone and its implications for the activation mechanism
Q27644196The crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity
Q30349872The crystal structure of yeast copper thionein: the solution of a long-lasting enigma.
Q27630892The crystal structures of Apo and complexed Saccharomyces cerevisiae GNA1 shed light on the catalytic mechanism of an amino-sugar N-acetyltransferase
Q27631583The crystallographic structure of the mannitol 2-dehydrogenase NADP+ binary complex from Agaricus bisporus
Q27678972The cytoplasmic coiled-coil mediates cooperative gating temperature sensitivity in the voltage-gated H(+) channel Hv1
Q27656812The dimer formed by the periplasmic domain of EpsL from the Type 2 Secretion System of Vibrio parahaemolyticus
Q27639655The disulfide bond isomerase DsbC is activated by an immunoglobulin-fold thiol oxidoreductase: crystal structure of the DsbC-DsbDalpha complex
Q27641933The evolutionarily conserved trimeric structure of CutA1 proteins suggests a role in signal transduction
Q34326406The family 11 carbohydrate-binding module of Clostridium thermocellum Lic26A-Cel5E accommodates beta-1,4- and beta-1,3-1,4-mixed linked glucans at a single binding site
Q30159757The first crystal structure of class III superoxide reductase from Treponema pallidum
Q27653655The first structure of a cold-adapted superoxide dismutase (SOD): biochemical and structural characterization of iron SOD fromAliivibrio salmonicida
Q27650815The first structure of dipeptidyl-peptidase III provides insight into the catalytic mechanism and mode of substrate binding
Q38325706The fucose-binding lectin from Ralstonia solanacearum. A new type of beta-propeller architecture formed by oligomerization and interacting with fucoside, fucosyllactose, and plant xyloglucan
Q34157437The genesis of high-throughput structure-based drug discovery using protein crystallography
Q44326923The high resolution crystal structure of rat liver AKR7A1: understanding the substrate specificites of the AKR7 family.
Q27674322The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism
Q27638946The importance of the conserved Arg191-Asp227 salt bridge of triosephosphate isomerase for folding, stability, and catalysis
Q37380845The long-chain fatty acid sensor, PsrA, modulates the expression of rpoS and the type III secretion exsCEBA operon in Pseudomonas aeruginosa
Q24599244The magic triangle goes MAD: experimental phasing with a bromine derivative
Q27683564The major cockroach allergen Bla g 4 binds tyramine and octopamine
Q27640898The matrix protein VP40 from Ebola virus octamerizes into pore-like structures with specific RNA binding properties
Q37471199The membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus binds the dipeptide GlyMet via side chain interactions
Q34480441The molecular architecture of the metalloprotease FtsH.
Q27661881The molecular basis of glycogen breakdown and transport in Streptococcus pneumoniae
Q27641782The molecular basis of vitamin E retention: structure of human alpha-tocopherol transfer protein
Q34302351The molecular structure and catalytic mechanism of a novel carboxyl peptidase from Scytalidium lignicolum
Q36426545The molecular structure of Rv1873, a conserved hypothetical protein from Mycobacterium tuberculosis, at 1.38 A resolution
Q80618093The multifunctional human p100 protein 'hooks' methylated ligands
Q27673500The multiple Tudor domain-containing protein TDRD1 is a molecular scaffold for mouse Piwi proteins and piRNA biogenesis factors
Q30369977The olfactomedin domain from gliomedin is a β-propeller with unique structural properties.
Q24644821The oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs)
Q30457119The quality and validation of structures from structural genomics
Q27679374The role of a voltage-dependent Ca2+ channel intracellular linker: a structure-function analysis
Q27640944The sequence and crystal structure of the alpha-amino acid ester hydrolase from Xanthomonas citri define a new family of beta-lactam antibiotic acylases
Q27696038The side chain of a glycosylated asparagine residue is important for the stability of isopullulanase
Q35264433The significance of G protein-coupled receptor crystallography for drug discovery
Q27650520The structural basis for cap binding by influenza virus polymerase subunit PB2
Q27638772The structural basis for catalysis and specificity of the Pseudomonas cellulosa alpha-glucuronidase, GlcA67A
Q27654215The structural basis for peptide selection by the transport receptor OppA
Q27655456The structural basis for the difference in absorbance spectra for the FMO antenna protein from various green sulfur bacteria
Q28248816The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3
Q24596953The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase gcn5p
Q27631126The structural basis of acyl coenzyme A-dependent regulation of the transcription factor FadR
Q27641813The structural basis of receptor-binding by Escherichia coli associated with diarrhea and septicemia
Q28487093The structural basis of signal transduction for the response regulator PrrA from Mycobacterium tuberculosis
Q27628928The structural basis of the catalytic mechanism and regulation of glucose-1-phosphate thymidylyltransferase (RmlA)
Q27674486The structural characterization of a prophage-encoded extracellular DNase from Streptococcus pyogenes
Q27658328The structure and NO binding properties of the nitrophorin-like heme-binding protein from Arabidopsis thaliana gene locus At1g79260.1
Q27673075The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase
Q30434632The structure and ligand binding properties of the B. subtilis YkoF gene product, a member of a novel family of thiamin/HMP-binding proteins
Q33979555The structure and mechanism of serine acetyltransferase from Escherichia coli
Q35951067The structure at 1.7 A resolution of the protein product of the At2g17340 gene from Arabidopsis thaliana
Q35950614The structure at 2.4 A resolution of the protein from gene locus At3g21360, a putative Fe(II)/2-oxoglutarate-dependent enzyme from Arabidopsis thaliana
Q35994874The structure at 2.5 A resolution of human basophilic leukemia-expressed protein BLES03
Q27636942The structure of 3-methylaspartase from Clostridium tetanomorphum functions via the common enolase chemical step
Q24540326The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis.
Q28486666The structure of MbtI from Mycobacterium tuberculosis, the first enzyme in the biosynthesis of the siderophore mycobactin, reveals it to be a salicylate synthase
Q27638755The structure of Neurospora crassa 3-carboxy-cis,cis-muconate lactonizing enzyme, a beta propeller cycloisomerase
Q24542391The structure of Rauvolfia serpentina strictosidine synthase is a novel six-bladed beta-propeller fold in plant proteins
Q30341567The structure of Ski8p, a protein regulating mRNA degradation: Implications for WD protein structure
Q27648812The structure of a full-length response regulator from Mycobacterium tuberculosis in a stabilized three-dimensional domain-swapped, activated state
Q31042840The structure of an ancient conserved domain establishes a structural basis for stable histidine phosphorylation and identifies a new family of adenosine-specific kinases.
Q27646666The structure of an archaeal ribose-5-phosphate isomerase fromMethanocaldococcus jannaschii(MJ1603)
Q24679546The structure of human ADP-ribosylhydrolase 3 (ARH3) provides insights into the reversibility of protein ADP-ribosylation
Q27643642The structure of human collapsin response mediator protein 2, a regulator of axonal growth
Q24297646The structure of mammalian serine racemase: evidence for conformational changes upon inhibitor binding
Q27678921The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes
Q27646604The structure of pyogenecin immunity protein, a novel bacteriocin-like immunity protein from Streptococcus pyogenes
Q24553353The structure of siglec-7 in complex with sialosides: leads for rational structure-based inhibitor design
Q27675201The structure of the CS1 pilus of enterotoxigenic Escherichia coli reveals structural polymorphism
Q42741839The structure of the GPIb-filamin A complex.
Q27666462The structure of the Helicobacter pylori ferric uptake regulator Fur reveals three functional metal binding sites
Q27666639The structure of the Klf4 DNA-binding domain links to self-renewal and macrophage differentiation
Q34305323The structure of the MAPK scaffold, MP1, bound to its partner, p14. A complex with a critical role in endosomal map kinase signaling
Q27636667The structure of the feruloyl esterase module of xylanase 10B from Clostridium thermocellum provides insights into substrate recognition
Q27644101The structure of the first representative of Pfam family PF09836 reveals a two-domain organization and suggests involvement in transcriptional regulation
Q27653890The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2)
Q27644107The structure of the macrophage signal regulatory protein alpha (SIRPalpha) inhibitory receptor reveals a binding face reminiscent of that used by T cell receptors
Q30490997The structure of the myosin VI motor reveals the mechanism of directionality reversal
Q42623791The structure of the organic hydroperoxide resistance protein from Deinococcus radiodurans. Do conformational changes facilitate recycling of the redox disulfide?
Q27641688The structure of the periplasmic ligand-binding domain of the sensor kinase CitA reveals the first extracellular PAS domain
Q27641750The structure of the receptor-binding domain of the bacteriophage T4 short tail fibre reveals a knitted trimeric metal-binding fold
Q27650828The structure of “defective in induced resistance” protein ofArabidopsis thaliana, DIR1, reveals a new type of lipid transfer protein
Q27641881The structure ofPseudomonasP51 Cl-muconate lactonizing enzyme: Co-evolution of structure and dynamics with the dehalogenation function
Q27673410The substrate/product-binding modes of a novel GH120 β-xylosidase (XylC) from Thermoanaerobacterium saccharolyticum JW/SL-YS485
Q27652926The sulfur atoms of the substrate CoA and the catalytic cysteine are required for a productive mode of substrate binding in bacterial biosynthetic thiolase, a thioester-dependent enzyme
Q27655626The thermo- and acido-stable ORF-99 from the archaeal virus AFV1
Q27642875The thrH gene product of Pseudomonas aeruginosa is a dual activity enzyme with a novel phosphoserine:homoserine phosphotransferase activity
Q27654465The three-dimensional structure of the cytoplasmic domains of EpsF from the type 2 secretion system of Vibrio cholerae
Q27641400The three-dimensional structure of the human NK cell receptor NKp44, a triggering partner in natural cytotoxicity
Q54484266The three-dimensional structures of tick carboxypeptidase inhibitor in complex with A/B carboxypeptidases reveal a novel double-headed binding mode.
Q27674290The unique structure of carbonic anhydrase αCA1 from Chlamydomonas reinhardtii
Q50973336The use of VLD (vive la difference) in the molecular-replacement approach: a pipeline.
Q27667775The ygeW encoded protein from Escherichia coli is a knotted ancestral catabolic transcarbamylase
Q30274897The young person's guide to the PDB.
Q27934958The zinc finger protein Ynr046w is plurifunctional and a component of the eRF1 methyltransferase in yeast
Q42917477Thiolation-enhanced substrate recognition by D-alanyl carrier protein ligase DltA from Bacillus cereus
Q27650527Thioredoxin A Active-Site Mutants Form Mixed Disulfide Dimers That Resemble Enzyme–Substrate Reaction Intermediates
Q53623694Three-dimensional structure of AzoR from Escherichia coli. An oxidereductase conserved in microorganisms.
Q27638849Three-dimensional structure of human gamma -glutamyl hydrolase. A class I glatamine amidotransferase adapted for a complex substate
Q27649335Three-dimensional structure/function analysis of SCP-2-like2 reveals differences among SCP-2 family members
Q30435031To automate or not to automate: this is the question
Q27637363Toward a structural understanding of the dehydratase mechanism
Q36904963Tracking solvent and protein movement during CO2 release in carbonic anhydrase II crystals
Q27680560Transient Protein States in Designing Inhibitors of the MDM2-p53 Interaction
Q27649730Transitive homology-guided structural studies lead to discovery of Cro proteins with 40% sequence identity but different folds
Q41954823Trapping a 96 degrees domain rotation in two distinct conformations by engineered disulfide bridges
Q27639594Trimeric crystal structure of the glycoside hydrolase family 42 beta-galactosidase from Thermus thermophilus A4 and the structure of its complex with galactose
Q27641895Trypsin revisited: crystallography AT (SUB) atomic resolution and quantum chemistry revealing details of catalysis
Q27684053Two Amino Acid Residues Confer Different Binding Affinities of Abelson Family Kinase Src Homology 2 Domains for Phosphorylated Cortactin
Q27670502Two autonomous structural modules in the fimbrial shaft adhesin FimA mediate Actinomyces interactions with streptococci and host cells during oral biofilm development
Q27653977Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin
Q27653144UPF201 Archaeal Specific Family Members Reveal Structural Similarity to RNA-Binding Proteins but Low Likelihood for RNA-Binding Function
Q27675397UV damage endonuclease employs a novel dual-dinucleotide flipping mechanism to recognize different DNA lesions
Q27644072Unique Thermodynamic Response of Tipranavir to Human Immunodeficiency Virus Type 1 Protease Drug Resistance Mutations
Q28487595Unique features of the sodC-encoded superoxide dismutase from Mycobacterium tuberculosis, a fully functional copper-containing enzyme lacking zinc in the active site
Q93177828Unique mechanism of target recognition by PfoI restriction endonuclease of the CCGG-family
Q27658200Unusual Diheme Conformation of the Heme-Degrading Protein from Mycobacterium tuberculosis
Q27635472Unusual binding properties of the SH3 domain of the yeast actin-binding protein Abp1: structural and functional analysis
Q30418666Using surface-bound rubidium ions for protein phasing
Q27678938Utility of anion and cation combinations for phasing of protein structures
Q27651621Vaccinia Virus Proteins A52 and B14 Share a Bcl-2–Like Fold but Have Evolved to Inhibit NF-κB rather than Apoptosis
Q30370948Vaccinia virus protein A49 is an unexpected member of the B-cell Lymphoma (Bcl)-2 protein family
Q27689547Versatile C(3)-symmetric scaffolds and their use for covalent stabilization of the foldon trimer
Q27657876Versatile Loops in Mycocypins Inhibit Three Protease Families
Q34474432Vitamin B6 biosynthesis by the malaria parasite Plasmodium falciparum: biochemical and structural insights
Q27652067X-ray Crystal Structure of a TRPM Assembly Domain Reveals an Antiparallel Four-stranded Coiled-coil
Q47589092X-ray crystal structure of Escherichia coli HspQ, a protein involved in the retardation of replication initiation
Q27636876X-ray crystal structure of MTH938 from Methanobacterium thermoautotrophicum at 2.2 A resolution reveals a novel tertiary protein fold
Q27631420X-ray crystal structure of the trimeric N-terminal domain of gephyrin
Q27639153X-ray crystallographic studies on butyryl-ACP reveal flexibility of the structure around a putative acyl chain binding site
Q29619405X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution
Q27639181X-ray structure and ligand binding study of a moth chemosensory protein
Q27650791X-ray structure of ILL2, an auxin-conjugate amidohydrolase fromArabidopsis thaliana
Q27639349X-ray structure of Saccharomyces cerevisiae homologous mitochondrial matrix factor 1 (Hmf1)
Q27639214X-ray structure of a dihydropyrimidinase from Thermus sp. at 1.3 A resolution
Q27641402X-ray structure of human acid-β-glucosidase, the defective enzyme in Gaucher disease
Q33245653X-ray structure of potato epoxide hydrolase sheds light on substrate specificity in plant enzymes
Q34319723X-ray structure of tRNA pseudouridine synthase TruD reveals an inserted domain with a novel fold.
Q41092772X-ray structure of the membrane-bound cytochrome c quinol dehydrogenase NrfH reveals novel haem coordination
Q24535893X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation.
Q27639646X-ray structure of two crystalline forms of a streptomycete ribonuclease with cytotoxic activity
Q27653937X-ray structure ofDanio reriosecretagogin: A hexa-EF-hand calcium sensor
Q27646612X-ray structures and thermodynamics of the interaction of PA-IIL from Pseudomonas aeruginosa with disaccharide derivatives
Q27648687X-ray structures of two proteins belonging to Pfam DUF178 revealed unexpected structural similarity to the DUF191 Pfam family
Q30843533Xylan utilization in human gut commensal bacteria is orchestrated by unique modular organization of polysaccharide-degrading enzymes
Q38318369Xyloglucan is recognized by carbohydrate-binding modules that interact with beta-glucan chains
Q27679921Yeast Mnn9 is both a priming glycosyltransferase and an allosteric activator of mannan biosynthesis
Q27680554Zebavidin - An Avidin-Like Protein from Zebrafish
Q27657481Zinc-Independent Folate Biosynthesis: Genetic, Biochemical, and Structural Investigations Reveal New Metal Dependence for GTP Cyclohydrolase IB
Q34390229[1,2,4]triazolo[4,3-a]phthalazines: inhibitors of diverse bromodomains
Q24300775p31comet blocks Mad2 activation through structural mimicry
Q36031413phenix.mr_rosetta: molecular replacement and model rebuilding with Phenix and Rosetta
Q27674238α-Galactosidase/Sucrose Kinase (AgaSK), a Novel Bifunctional Enzyme from the Human Microbiome Coupling Galactosidase and Kinase Activities
Q36673699α/β coiled coils

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