Dengue viremia titer, antibody response pattern, and virus serotype correlate with disease severity

scientific article (publication date: 2000)

Dengue viremia titer, antibody response pattern, and virus serotype correlate with disease severity is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1086/315215
P3181OpenCitations bibliographic resource ID175684
P698PubMed publication ID10608744
P5875ResearchGate publication ID51354979

P50authorBruce L. InnisQ39447629
P2093author name stringGreen S
Ennis FA
Raengsakulrach B
Vaughn DW
Nisalak A
Kalayanarooj S
Nimmannitya S
Rothman AL
Suntayakorn S
Endy TP
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectvirusQ808
antibodyQ79460
Dengue virusQ476209
P304page(s)2-9
P577publication date2000-01-01
P1433published inJournal of Infectious DiseasesQ4051141
P1476titleDengue viremia titer, antibody response pattern, and virus serotype correlate with disease severity
P478volume181

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Q36146301Elevated levels of vitamin D and deficiency of mannose binding lectin in dengue hemorrhagic fever
Q26825663Endothelial cells in dengue hemorrhagic fever
Q29196526Enhancement of Zika virus pathogenesis by preexisting antiflavivirus immunity
Q47558474Enhancing the antiviral potency of ER α-glucosidase inhibitor IHVR-19029 against hemorrhagic fever viruses in vitro and in vivo
Q24289012Epidemiological Scenario of Dengue in Brazil
Q21131163Epidemiological risk factors associated with high global frequency of inapparent dengue virus infections
Q40125629Epidemiology and characteristics of the dengue outbreak in Guangdong, Southern China, in 2014.
Q35866928Epidemiology of Infant Dengue Cases Illuminates Serotype-Specificity in the Interaction between Immunity and Disease, and Changes in Transmission Dynamics
Q27477735Etiology of interepidemic periods of mosquito-borne disease
Q40527785Evaluation by flow cytometry of antibody-dependent enhancement (ADE) of dengue infection by sera from Thai children immunized with a live-attenuated tetravalent dengue vaccine
Q37723567Evaluation of Non-Structural Protein-1(NS1) positive patients of 2013 dengue outbreak in Khyber Pakhtunkhwa, Pakistan.
Q27480925Evaluation of a Commercial Real-Time PCR Kit for Detection of Dengue Virus in Samples Collected during an Outbreak in Goiania, Central Brazil, in 2005
Q27488388Evaluation of an Epitope-Blocking Enzyme-Linked Immunosorbent Assay for the Diagnosis of West Nile Virus Infections in Humans
Q26768523Evaluation of antiviral activities of Houttuynia cordata Thunb. extract, quercetin, quercetrin and cinanserin on murine coronavirus and dengue virus infection
Q35350529Evaluation of commercially available diagnostic tests for the detection of dengue virus NS1 antigen and anti-dengue virus IgM antibody
Q39346277Evaluation of diagnostic tests: dengue
Q34761908Evaluation of host and viral factors associated with severe dengue based on the 2009 WHO classification
Q34522384Evaluation of protection induced by a dengue virus serotype 2 envelope domain III protein scaffold/DNA vaccine in non-human primates.
Q27485433Evaluation of the Langat/dengue 4 chimeric virus as a live attenuated tick-borne encephalitis vaccine for safety and immunogenicity in healthy adult volunteers
Q84957829Evaluation of the antiviral activity of orlistat (tetrahydrolipstatin) against dengue virus, Japanese encephalitis virus, Zika virus and chikungunya virus
Q34075766Evaluation of the traditional and revised WHO classifications of Dengue disease severity
Q28204656Evasion of innate and adaptive immunity by flaviviruses
Q33609685Evasion of the human innate immune system by dengue virus
Q40291127Eventual role of asymptomatic cases of dengue for the introduction and spread of dengue viruses in non-endemic regions
Q40363094Evidence for inter- and intra-genotypic variations in dengue serotype 4 viruses representing predominant and non-predominant genotypes co-circulating in Thailand from 1977 to 2001.
Q39565102Evolution of attenuating mutations in dengue-2 strain S16803 PDK50 vaccine and comparison of growth kinetics with parent virus
Q39611325Expression of enhancing-activity-free neutralizing antibody against dengue type 1 virus in plasmid-inoculated mice
Q26257542Extended Evaluation of Virological, Immunological and Pharmacokinetic Endpoints of CELADEN: A Randomized, Placebo-Controlled Trial of Celgosivir in Dengue Fever Patients
Q34531142Factors influencing dengue virus isolation by C6/36 cell culture and mosquito inoculation of nested PCR-positive clinical samples
Q38916168Fever after a stay in the tropics. Part 2: Common imported tropical diseases
Q24289308Fever from the forest: prospects for the continued emergence of sylvatic dengue virus and its impact on public health
Q64359207Fever in travellers returning from the tropics
Q91913005Fever in travellers returning from the tropics
Q31156754First experimental in vivo model of enhanced dengue disease severity through maternally acquired heterotypic dengue antibodies
Q55519030Flavivirus serocomplex cross-reactive immunity is protective by activating heterologous memory CD4 T cells.
Q35632639Fluorescently labeled dengue viruses as probes to identify antigen-specific memory B cells by multiparametric flow cytometry
Q56877982Focus: Dengue
Q40333405Frequency alterations in key innate immune cell components in the peripheral blood of dengue patients detected by FACS analysis
Q24737418From research to phase III: preclinical, industrial and clinical development of the Sanofi Pasteur tetravalent dengue vaccine
Q34738972Full serotype- and group-specific NS1 capture enzyme-linked immunosorbent assay for rapid differential diagnosis of dengue virus infection
Q35601805Functionality of dengue virus specific memory T cell responses in individuals who were hospitalized or who had mild or subclinical dengue infection
Q28474384Gene expression patterns of dengue virus-infected children from nicaragua reveal a distinct signature of increased metabolism
Q27478354Generation and Characterization of Monoclonal Antibodies against Dengue Virus Type 1 for Epitope Mapping and Serological Detection by Epitope-Based Peptide Antigens
Q39273369Generation and characterization of potential dengue vaccine candidates based on domain III of the envelope protein and the capsid protein of the four serotypes of dengue virus.
Q39126155Generation and preclinical evaluation of a DENV-1/2 prM+E chimeric live attenuated vaccine candidate with enhanced prM cleavage.
Q37698942Generation of human single-chain variable fragment antibodies specific to dengue virus non-structural protein 1 that interfere with the virus infectious cycle
Q34759091Genetic and phenotypic characterization of manufacturing seeds for a tetravalent dengue vaccine (DENVax).
Q92416661Genetic risk for dengue hemorrhagic fever and dengue fever in multiple ancestries
Q28943386Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1
Q33638451Genome-wide expression profiling deciphers host responses altered during dengue shock syndrome and reveals the role of innate immunity in severe dengue
Q36172100Genome-wide patterns of intrahuman dengue virus diversity reveal associations with viral phylogenetic clade and interhost diversity
Q28073351Genomic approaches for understanding dengue: insights from the virus, vector, and host
Q45324483Geraniin extracted from the rind of Nephelium lappaceum binds to dengue virus type-2 envelope protein and inhibits early stage of virus replication.
Q24736362Global spread of dengue virus types: mapping the 70 year history
Q56766779Global spread of epidemic dengue: the influence of environmental change
Q35993466HLA Class I Supertype Associations With Clinical Outcome of Secondary Dengue Virus Infections in Ethnic Thais
Q40569492HLA-A and -B allele associations with secondary dengue virus infections correlate with disease severity and the infecting viral serotype in ethnic Thais.
Q40293331HLA-A*01 allele: a risk factor for dengue haemorrhagic fever in Brazil's population
Q35057781HLA-A*33:01 as protective allele for severe dengue in a population of Filipino children
Q40409069Heat shock effect upon dengue virus replication into U937 cells.
Q34763787Heterotypic dengue infection with live attenuated monotypic dengue virus vaccines: implications for vaccination of populations in areas where dengue is endemic
Q40152182High Anti-Dengue Virus Activity of the OAS Gene Family Is Associated With Increased Severity of Dengue
Q27481682High Pro-Inflammatory Cytokine Secretion and Loss of High Avidity Cross-Reactive Cytotoxic T-Cells during the Course of Secondary Dengue Virus Infection
Q29618174High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever
Q28486302High content screening of a kinase-focused library reveals compounds broadly-active against dengue viruses
Q33419779High producing tumor necrosis factor alpha gene alleles in protection against severe manifestations of dengue
Q39799030High rate of unrecognized dengue virus infection in parts of the rainforest region of Nigeria.
Q33877767High-dimensional CyTOF analysis of dengue virus-infected human DCs reveals distinct viral signatures
Q35665847High-resolution analysis of intrahost genetic diversity in dengue virus serotype 1 infection identifies mixed infections
Q40147299Higher levels of dengue-virus-specific IgG and IgA during pre-defervescence associated with primary dengue hemorrhagic fever
Q27488302Highly Sensitive Detection of Dengue Virus Nucleic Acid in Samples from Clinically Ill Patients
Q36096412Honokiol, a Lignan Biphenol Derived from the Magnolia Tree, Inhibits Dengue Virus Type 2 Infection
Q27482207Host Gene Expression Profiling of Dengue Virus Infection in Cell Lines and Patients
Q38002407Host genetic susceptibility to severe dengue infection
Q37793734How Innate Immune Mechanisms Contribute to Antibody-Enhanced Viral Infections
Q33853984How season and serotype determine dengue transmissibility
Q26314609Human antibody response to dengue virus: implications for dengue vaccine design
Q25161212Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus
Q40585577Human dendritic cells as targets of dengue virus infection
Q27468843Human heme oxygenase 1 is a potential host cell factor against dengue virus replication
Q37995555Human poly- and cross-reactive anti-viral antibodies and their impact on protection and pathology
Q24658429Humanized mice show clinical signs of dengue fever according to infecting virus genotype
Q47558315Humoral Immune Responses Against Zika Virus Infection and the Importance of Preexisting Flavivirus Immunity
Q29994510Humoral cross-reactivity between Zika and dengue viruses: implications for protection and pathology
Q27305770IFN-γ production depends on IL-12 and IL-18 combined action and mediates host resistance to dengue virus infection in a nitric oxide-dependent manner
Q39034933IL-22 modulates IL-17A production and controls inflammation and tissue damage in experimental dengue infection
Q62485484Identification of Broad-Spectrum Antiviral Compounds by Targeting Viral Entry
Q26694068Identification of RNA Binding Proteins Associated with Dengue Virus RNA in Infected Cells Reveals Temporally Distinct Host Factor Requirements
Q35807844Identification of clinical factors associated with severe dengue among Thai adults: a prospective study
Q39781949Identification of mutations in a candidate dengue 4 vaccine strain 341750 PDK20 and construction of a full-length cDNA clone of the PDK20 vaccine candidate
Q100428036Identification of the phytobioactive Polygonum cuspidatum as an antiviral source for restricting dengue virus entry
Q33438726IgG antibodies to dengue enhanced for FcγRIIIA binding determine disease severity
Q37584342Imino sugar glucosidase inhibitors as broadly active anti-filovirus agents
Q27490592Immature Dengue Virus: A Veiled Pathogen?
Q35179653Immature dengue virus is infectious in human immature dendritic cells via interaction with the receptor molecule DC-SIGN.
Q33430763Immune Response to Dengue Virus Infection in Pediatric Patients in New Delhi, India--Association of Viremia, Inflammatory Mediators and Monocytes with Disease Severity
Q38059915Immune evasion strategies of flaviviruses
Q37901360Immunity to dengue virus: a tale of original antigenic sin and tropical cytokine storms
Q34261827Immunodominance changes as a function of the infecting dengue virus serotype and primary versus secondary infection
Q34165624Immunodominant T-cell responses to dengue virus NS3 are associated with DHF.
Q33841915Immunological and viral determinants of dengue severity in hospitalized adults in Ha Noi, Viet Nam.
Q51131051Immunological serotype interactions and their effect on the epidemiological pattern of dengue.
Q35613349Immunology and immunopathogenesis of dengue disease
Q39410861Immunopathogenesis Versus Protection in Dengue Virus Infections
Q27468884Impact of dengue virus (DENV) co-infection on clinical manifestations, disease severity and laboratory parameters
Q38157106Impact of prior flavivirus immunity on Zika virus infection in rhesus macaques
Q38896966Impedimetric cell-based biosensor for real-time monitoring of cytopathic effects induced by dengue viruses
Q27478084Improved Molecular Detection of Dengue Virus Serotype 1 Variants
Q51733262Improvement of the Dengue Virus (DENV) Nonhuman Primate Model via a Reverse Translational Approach Based on Dengue Vaccine Clinical Efficacy Data against DENV-2 and -4.
Q26314599Improving dengue virus capture rates in humans and vectors in Kamphaeng Phet Province, Thailand, using an enhanced spatiotemporal surveillance strategy
Q30250977In a randomized trial, the live attenuated tetravalent dengue vaccine TV003 is well-tolerated and highly immunogenic in subjects with flavivirus exposure prior to vaccination
Q40309971Incidence and seroprevalence of dengue virus infections in Australian travellers to Asia.
Q39495783Induced autophagy reduces virus output in dengue infected monocytic cells
Q37500519Induction of neutralizing antibodies against four serotypes of dengue viruses by MixBiEDIII, a tetravalent dengue vaccine
Q40307795Infection and activation of human peripheral blood monocytes by dengue viruses through the mechanism of antibody-dependent enhancement.
Q27469687Infection of human cells by dengue virus is modulated by different cell types and viral strains
Q27485321Infection-Enhancing and -Neutralizing Activities of Mouse Monoclonal Antibodies against Dengue Type 2 and 4 Viruses Are Controlled by Complement Levels
Q30396651Influenza and dengue virus co-infection impairs monocyte recruitment to the lung, increases dengue virus titers, and exacerbates pneumonia
Q37347305Inhibition of Polyamine Biosynthesis Is a Broad-Spectrum Strategy against RNA Viruses
Q90024871Inhibition of dengue virus replication in monocyte-derived dendritic cells by vivo-morpholino oligomers
Q36228889Innate immune responses to dengue virus
Q26314406Interaction of a dengue virus NS1-derived peptide with the inhibitory receptor KIR3DL1 on natural killer cells
Q34633606International dispersal of dengue through air travel: importation risk for Europe
Q39624994Intra-genotypic variation of predominant genotype II strains of dengue type-3 virus isolated during different epidemics in Thailand from 1973 to 2001.
Q91605068Intra-host growth kinetics of dengue virus in the mosquito Aedes aegypti
Q34671059Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexes
Q40528042Introduction of mutations into the non-structural genes or 3' untranslated region of an attenuated dengue virus type 4 vaccine candidate further decreases replication in rhesus monkeys while retaining protective immunity
Q38870485Investigational drugs in early development for treating dengue infection.
Q90353798Isolation and molecular characterization of dengue virus clinical isolates from pediatric patients in New Delhi
Q33597509Isolation of dengue virus from the upper respiratory tract of four patients with dengue fever.
Q38779406Issues in contemporary and potential future molecular diagnostics for dengue.
Q30395396Issues related to recent dengue vaccine development
Q115204511Ivermectin Accelerates Circulating Nonstructural Protein 1 (NS1) Clearance in Adult Dengue Patients: A Combined Phase 2/3 Randomized Double-blinded Placebo Controlled Trial
Q40374538JNK phosphorylation, induced during dengue virus infection, is important for viral infection and requires the presence of cholesterol
Q38618056Key concepts, strategies, and challenges in dengue vaccine development: an opportunity for sub-unit candidates?
Q33394239Kinetics of plasma viremia and soluble nonstructural protein 1 concentrations in dengue: differential effects according to serotype and immune status
Q28476805Kinetics of viremia and NS1 antigenemia are shaped by immune status and virus serotype in adults with dengue
Q33424504Laboratory-confirmed Dengue in Children in Three Regional Hospitals in the Philippines in 2009-2010.
Q35146621Lack of clinical manifestations in asymptomatic dengue infection is attributed to broad down-regulation and selective up-regulation of host defence response genes
Q37223621Larval Temperature-Food Effects on Adult Mosquito Infection and Vertical Transmission of Dengue-1 Virus
Q36615111Lessons from malaria control to help meet the rising challenge of dengue
Q27315772Lethal antibody enhancement of dengue disease in mice is prevented by Fc modification
Q40418273Limited replication of yellow fever 17DD and 17D-Dengue recombinant viruses in rhesus monkeys
Q40508579Lineage extinction and replacement in dengue type 1 virus populations are due to stochastic events rather than to natural selection
Q36396156Liposome-mediated delivery of iminosugars enhances efficacy against dengue virus in vivo
Q33743890Live attenuated tetravalent dengue virus host range vaccine is immunogenic in African green monkeys following a single vaccination
Q33380611Liver injury caused by antibodies against dengue virus nonstructural protein 1 in a murine model
Q34160073Liver involvement associated with dengue infection in adults in Vietnam
Q35105926Lovastatin delays infection and increases survival rates in AG129 mice infected with dengue virus serotype 2
Q35763159Lower Low-Density Lipoprotein Cholesterol Levels Are Associated with Severe Dengue Outcome
Q34629343Mapping the interactions of dengue virus NS1 protein with human liver proteins using a yeast two-hybrid system: identification of C1q as an interacting partner
Q34025762Maternal and perinatal outcomes of dengue in PortSudan, Eastern Sudan
Q35097469Maternal antibody and viral factors in the pathogenesis of dengue virus in infants
Q92162622Mathematics of dengue transmission dynamics: Roles of vector vertical transmission and temperature fluctuations
Q24570135Maturation of dengue virus nonstructural protein 4B in monocytes enhances production of dengue hemorrhagic fever-associated chemokines and cytokines
Q34306877Mechanistic study of broadly neutralizing human monoclonal antibodies against dengue virus that target the fusion loop
Q34088956Memory CD8+ T cells from naturally acquired primary dengue virus infection are highly cross-reactive
Q36026358Meta-Analysis of Dengue Severity during Infection by Different Dengue Virus Serotypes in Primary and Secondary Infections
Q41722923Meta-analysis of biomarkers for severe dengue infections.
Q35935426Metabolomics-Based Discovery of Small Molecule Biomarkers in Serum Associated with Dengue Virus Infections and Disease Outcomes
Q56395792Methods to discriminate primary from secondary dengue during acute symptomatic infection
Q28742358Microevolution and virulence of dengue viruses
Q38247016Micronutrients and dengue
Q35009344Minimal within-host dengue models highlight the specific roles of the immune response in primary and secondary dengue infections
Q27468903Miscarriage following dengue virus 3 infection in the first six weeks of pregnancy of a dengue virus-naive traveller returning from Bali to Italy, April 2016
Q26310760Modeling Mosquito-Borne Disease Spread in U.S. Urbanized Areas: The Case of Dengue in Miami
Q57092750Modeling the Heterogeneity of Dengue Transmission in a City
Q35082837Models of the impact of dengue vaccines: a review of current research and potential approaches
Q54217627Modulation of Dengue/Zika Virus Pathogenicity by Antibody-Dependent Enhancement and Strategies to Protect Against Enhancement in Zika Virus Infection.
Q90396144Molecular & serological study of dengue virus-infected patients attending a tertiary hospital of Dhaka city, Bangladesh (2013 to 2016)
Q64063103Molecular characterization of dengue virus reveals regional diversification of serotype 2 in Colombia
Q40141583Molecular characterization of the 17D-204 yellow fever vaccine
Q35716609Molecular detection and typing of dengue viruses from archived tissues of fatal cases by rt-PCR and sequencing: diagnostic and epidemiologic implications
Q27869771Molecular detection of Zika virus in blood and RNA load determination during the French Polynesian outbreak
Q40564210Molecular evolution and phylogeny of dengue type 4 virus in the Caribbean.
Q38045381Molecular mechanisms involved in antibody-dependent enhancement of dengue virus infection in humans
Q27488337Molecular mechanisms of antibody-mediated neutralisation of flavivirus infection
Q27489123Monoclonal antibody to dengue capsid protein: its application in dengue studies
Q24684689Monoclonal antibody-mediated enhancement of dengue virus infection in vitro and in vivo and strategies for prevention
Q24655645Mosquito Saliva Increases Endothelial Permeability in the Skin, Immune Cell Migration, and Dengue Pathogenesis during Antibody-Dependent Enhancement
Q27010151Mouse models to study dengue virus immunology and pathogenesis
Q27477548Murine Model for Dengue Virus-Induced Lethal Disease with Increased Vascular Permeability
Q35880177Myanmar dengue outbreak associated with displacement of serotypes 2, 3, and 4 by dengue 1.
Q55648073NS1 Antigenemia and Viraemia Load: Potential Markers of Progression to Dengue Fatal Outcome?
Q24194181NS1 antigen detecting assays for diagnosing acute dengue infection in people living in or returning from endemic countries
Q35034151Natural, persistent oscillations in a spatial multi-strain disease system with application to dengue
Q29618172Neutralization and antibody-dependent enhancement of dengue viruses
Q50099498Neutralization of antibody-enhanced dengue infection by VIS513, a pan serotype reactive monoclonal antibody targeting domain III of the dengue E protein
Q38093249New development in the diagnosis of dengue infections
Q35491639Next-generation dengue vaccines: novel strategies currently under development
Q57454669Nonalcoholic fatty liver disease is associated with increased hemoconcentration, thrombocytopenia, and longer hospital stay in dengue-infected patients with plasma leakage
Q37672305Novel Genetic and Molecular Tools for the Investigation and Control of Dengue Virus Transmission by Mosquitoes
Q34472346Novel antiviral activity of baicalein against dengue virus
Q34583461Novel benzoxazole inhibitor of dengue virus replication that targets the NS3 helicase
Q30390721Observed and projected drivers of emerging infectious diseases in Europe
Q36666340Of cascades and perfect storms: the immunopathogenesis of dengue haemorrhagic fever-dengue shock syndrome (DHF/DSS).
Q52593443Operational utility of the reverse-transcription recombinase polymerase amplification for detection of dengue virus.
Q27469986Optimized diagnosis of acute dengue fever in Swedish travelers by a combination of reverse transcription-PCR and immunoglobulin M detection
Q29619585Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever
Q27472938Paired charge-to-alanine mutagenesis of dengue virus type 4 NS5 generates mutants with temperature-sensitive, host range, and mouse attenuation phenotypes
Q38636217Paradoxical role of antibodies in dengue virus infections: considerations for prophylactic vaccine development
Q37851212Partial maturation: an immune-evasion strategy of dengue virus?
Q58997716Pathogenesis of Dengue Haemorrhagic Fever and Its Impact on Case Management
Q26766198Pathogenesis of Dengue: Dawn of a New Era
Q28729784Patterns of cellular immunity associated with experimental infection with rDEN2Δ30 (Tonga/74) supports its suitability as a human DENV challenge strain
Q35097474Patterns of gene transcript abundance in the blood of children with severe or uncomplicated dengue highlight differences in disease evolution and host response to dengue virus infection
Q33702837Patterns of host genome-wide gene transcript abundance in the peripheral blood of patients with acute dengue hemorrhagic fever
Q39017020Peptide inhibitors against dengue virus infection.
Q64236704Perspective: The promises of a holistic view of proteins-impact on antibody engineering and drug discovery
Q27490989Phase 1 Trial of the Dengue Virus Type 4 Vaccine Candidate rDEN4 30-4995 in Healthy Adult Volunteers
Q39835610Phenotypic analysis of dengue virus isolates associated with dengue fever and dengue hemorrhagic fever for cellular attachment, replication and interferon signaling ability
Q39472973Phenotypic and genotypic characterization of dengue virus isolates differentiates dengue fever and dengue hemorrhagic fever from dengue shock syndrome
Q27486912Phenotyping of peripheral blood mononuclear cells during acute dengue illness demonstrates infection and increased activation of monocytes in severe cases compared to classic dengue fever
Q98906699Phosphoproteomic analysis of dengue virus infected U937 cells and identification of pyruvate kinase M2 as a differentially phosphorylated phosphoprotein
Q34611164Phylodynamic analysis of the emergence and epidemiological impact of transmissible defective dengue viruses
Q40532518Phylogeography and molecular evolution of dengue 2 in the Caribbean basin, 1981-2000.
Q50255448Plasma leakage in dengue haemorrhagic fever
Q33194696Policymakers’ views on dengue fever/dengue haemorrhagic fever and the need for dengue vaccines in four southeast Asian countries
Q37572667Population structure of the dengue viruses, Aragua, Venezuela, 2006-2007. Insights into dengue evolution under hyperendemic transmission
Q30364184Porcine reproductive and respiratory syndrome (PRRS): an immune dysregulatory pandemic.
Q66679798Potent neutralizing antibodies elicited by dengue vaccine in rhesus macaque target diverse epitopes
Q36718596Potential of ancestral sylvatic dengue-2 viruses to re-emerge
Q34080726Potential opportunities and perils of imperfect dengue vaccines.
Q37609595Preclinical and clinical development of YFV 17D-based chimeric vaccines against dengue, West Nile and Japanese encephalitis viruses
Q21146686Predicting outcome from dengue
Q55084344Prediction and prevention of urban arbovirus epidemics: A challenge for the global virology community.
Q26315571Presence of three dengue serotypes in Ouagadougou (Burkina Faso): research and public health implications
Q33357597Preventive transfusion in dengue shock syndrome–is it necessary?
Q37007528Primary dengue haemorrhagic fever in patients from northeast of Brazil is associated with high levels of interferon-β during acute phase
Q36720238Primary dengue virus infections induce differential cytokine production in Mexican patients.
Q34345965Primary vaccination with low dose live dengue 1 virus generates a proinflammatory, multifunctional T cell response in humans
Q37010921Prior infection and passive transfer of neutralizing antibody prevent replication of severe acute respiratory syndrome coronavirus in the respiratory tract of mice
Q40037516Progress and Challenges Towards Point-of-Care Diagnostic Development for Dengue.
Q36825107Progress for dengue virus diseases. Towards the NS2B-NS3pro inhibition for a therapeutic-based approach
Q35009119Progress towards a dengue vaccine
Q30235612Prospects for a Zika Virus Vaccine
Q29619608Prospects for a dengue virus vaccine
Q27486945Protective and Enhancing HLA Alleles, HLA-DRB1*0901 and HLA-A*24, for Severe Forms of Dengue Virus Infection, Dengue Hemorrhagic Fever and Dengue Shock Syndrome
Q38731663Protective and immunological behavior of chimeric yellow fever dengue vaccine
Q39505039Proteomic analysis of an Aedes albopictus cell line infected with Dengue serotypes 1 and 3 viruses
Q30203504Prototype early warning systems for vector-borne diseases in Europe
Q35022653Public versus personal serotypes of a viral quasispecies.
Q24727667Quantitative competitive reverse transcription-PCR for quantification of dengue virus RNA
Q40290385Quasispecies of dengue virus
Q33338951Questions on viral population biology to complete dengue puzzle
Q27472702Randomized, Placebo-Controlled Trial of Nonpegylated and Pegylated Forms of Recombinant Human Alpha Interferon 2a for Suppression of Dengue Virus Viremia in Rhesus Monkeys
Q36992653Re-evaluation of the pathogenic roles of nonstructural protein 1 and its antibodies during dengue virus infection
Q27477646Recent Advances in Deciphering Viral and Host Determinants of Dengue Virus Replication and Pathogenesis
Q92859173Recent advances in understanding dengue
Q40197722Receptor-activated human α2-macroglobulin interacts with the envelope protein of dengue virus and protects virions from temperature-induced inactivation through multivalent binding
Q92471671Reciprocal immune enhancement of dengue and Zika virus infection in human skin
Q39028302Recombinant lipidated dengue-4 envelope protein domain III elicits protective immunity
Q27469474Recombinant, live-attenuated tetravalent dengue virus vaccine formulations induce a balanced, broad, and protective neutralizing antibody response against each of the four serotypes in rhesus monkeys
Q37108706Reconstructing historical changes in the force of infection of dengue fever in Singapore: implications for surveillance and control
Q37109553Reduced risk of disease during postsecondary dengue virus infections
Q58759739Refined efficacy estimates of the Sanofi Pasteur dengue vaccine CYD-TDV using machine learning
Q34374905Refining the global spatial limits of dengue virus transmission by evidence-based consensus
Q34087489Relationship between nonstructural protein 1 detection and plasma virus load in Dengue patients
Q36234359Replacement of pr gene with Japanese encephalitis virus pr using reverse genetics reduces antibody-dependent enhancement of dengue virus 2 infection
Q41926510Replication and Excretion of the Live Attenuated Tetravalent Dengue Vaccine CYD-TDV in a Flavivirus-Naive Adult Population: Assessment of Vaccine Viremia and Virus Shedding.
Q34058747Report of an NIAID workshop on dengue animal models
Q27022905Return of epidemic dengue in the United States: implications for the public health practitioner
Q35905785Revealing the molecular signatures of host-pathogen interactions.
Q37390846Reverse transcription loop-mediated isothermal amplification (RT-LAMP) for diagnosis of dengue
Q34640272Review article: Research on dengue during World War II revisited
Q38174301Revisiting dengue virus-host cell interaction: new insights into molecular and cellular virology
Q36181531Robust and Balanced Immune Responses to All 4 Dengue Virus Serotypes Following Administration of a Single Dose of a Live Attenuated Tetravalent Dengue Vaccine to Healthy, Flavivirus-Naive Adults
Q59790650Role of NS1 antibodies in the pathogenesis of acute secondary dengue infection
Q24655655Role of dendritic cells in antibody-dependent enhancement of dengue virus infection
Q92392677Role of microRNAs in antiviral responses to dengue infection
Q26860307Role of microparticles in dengue virus infection and its impact on medical intervention strategies
Q33393510Role of the chemokine receptors CCR1, CCR2 and CCR4 in the pathogenesis of experimental dengue infection in mice
Q28475368Roles of small GTPase Rac1 in the regulation of actin cytoskeleton during dengue virus infection
Q35131443Safety and immunogenicity of a tetravalent live-attenuated dengue vaccine in flavivirus-naive infants
Q37330751Scientific consultation on cell mediated immunity (CMI) in dengue and dengue vaccine development
Q45017668Scientific consultation on immunological correlates of protection induced by dengue vaccines report from a meeting held at the World Health Organization 17-18 November 2005.
Q54209744Screening of melatonin, α-tocopherol, folic acid, acetyl-L-carnitine and resveratrol for anti-dengue 2 virus activity.
Q36382589Sculpting humoral immunity through dengue vaccination to enhance protective immunity
Q27481677Secreted NS1 of Dengue Virus Attaches to the Surface of Cells via Interactions with Heparan Sulfate and Chondroitin Sulfate E
Q24558700Selection for virulent dengue viruses occurs in humans and mosquitoes
Q34855189Sequential waves of gene expression in patients with clinically defined dengue illnesses reveal subtle disease phases and predict disease severity
Q39302764Serological characterization of dengue virus infections observed among dengue hemorrhagic fever/dengue shock syndrome cases in upper Myanmar
Q27473050Serological differentiation of infections with dengue virus serotypes 1 to 4 by using recombinant antigens
Q40052267Serological, molecular and clinical correlates of dengue from a tertiary care centre in Chennai, India
Q27477501Serotype 1-Specific Monoclonal Antibody-Based Antigen Capture Immunoassay for Detection of Circulating Nonstructural Protein NS1: Implications for Early Diagnosis and Serotyping of Dengue Virus Infections
Q26314515Serotype influences on dengue severity: a cross-sectional study on 485 confirmed dengue cases in Vitória, Brazil
Q27491001Serotype-Specific Differences in the Risk of Dengue Hemorrhagic Fever: An Analysis of Data Collected in Bangkok, Thailand from 1994 to 2006
Q28289980Serotype-specific entry of dengue virus into liver cells: identification of the 37-kilodalton/67-kilodalton high-affinity laminin receptor as a dengue virus serotype 1 receptor
Q27468816Serum Procalcitonin and Peripheral Venous Lactate for Predicting Dengue Shock and/or Organ Failure: A Prospective Observational Study
Q97549435Serum chymase levels correlate with severe dengue warning signs and clinical fluid accumulation in hospitalized pediatric patients
Q58779698Serum fatty acids and progression from dengue fever to dengue haemorrhagic fever/dengue shock syndrome
Q36073685Serum levels of soluble vascular cell adhesion molecules may correlate with the severity of dengue virus-1 infection in adults
Q34500818Serum proteome and cytokine analysis in a longitudinal cohort of adults with primary dengue infection reveals predictive markers of DHF.
Q57731812Severe dengue and pregnancy: a review of data from the Rio de Janeiro, Brazil, surveillance information system
Q39264890Signaling by Antibodies: Recent Progress
Q54988577Simulation Model for Dynamics of Dengue with Innate and Humoral Immune Responses.
Q33709817Simulations to compare efficacies of tetravalent dengue vaccines and mosquito vector control
Q40140549Single point mutations in the helicase domain of the NS3 protein enhance dengue virus replicative capacity in human monocyte-derived dendritic cells and circumvent the type I interferon response.
Q34702394Single-reaction, multiplex, real-time rt-PCR for the detection, quantitation, and serotyping of dengue viruses
Q40469577Slower rates of clearance of viral load and virus-containing immune complexes in patients with dengue hemorrhagic fever.
Q33906261Space-time analysis of hospitalised dengue patients in rural Thailand reveals important temporal intervals in the pattern of dengue virus transmission
Q29353638Spatial Distribution of Epidemiological Cases of Dengue Fever in Suriname, 2001-2012.
Q27487319Spatial and Temporal Clustering of Dengue Virus Transmission in Thai Villages
Q38876970Spatial patterns of dengue cases in Brazil
Q27488364Structural Insights into the Mechanisms of Antibody-Mediated Neutralization of Flavivirus Infection: Implications for Vaccine Development
Q93162327Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody
Q38959153Sub-genomic RNA of defective interfering (D.I.) dengue viral particles is replicated in the same manner as full length genomes
Q39576880Substitution of the precursor peptide prevents anti-prM antibody-mediated antibody-dependent enhancement of dengue virus infection
Q56355933Successful Vaccines
Q27485468Superior infectivity for mosquito vectors contributes to competitive displacement among strains of dengue virus
Q38745464Suppressive Effects of the Site 1 Protease (S1P) Inhibitor, PF-429242, on Dengue Virus Propagation
Q27491097Sylvatic Dengue Viruses Share the Pathogenic Potential of Urban/Endemic Dengue Viruses
Q34500910Synchrony of sylvatic dengue isolations: a multi-host, multi-vector SIR model of dengue virus transmission in Senegal
Q47136667TLR2/MyD88 pathway-dependent regulation of dendritic cells by dengue virus promotes antibody-dependent enhancement via Th2-biased immunity
Q36118259Targeted mutagenesis as a rational approach to dengue virus vaccine development
Q90319214Targeting viral entry as a strategy for broad-spectrum antivirals
Q92593979Temperature impacts on dengue emergence in the United States: Investigating the role of seasonality and climate change
Q36192685Temperature-dependent production of pseudoinfectious dengue reporter virus particles by complementation
Q34075136The 2012 Madeira dengue outbreak: epidemiological determinants and future epidemic potential
Q26995782The Complexity of a Dengue Vaccine: A Review of the Human Antibody Response
Q27491317The Development of Therapeutic Antibodies That Neutralize Homologous and Heterologous Genotypes of Dengue Virus Type 1
Q37073267The Emerging Duck Flavivirus Is Not Pathogenic for Primates and Is Highly Sensitive to Mammalian Interferon Antiviral Signaling
Q39119333The Influence of Spatial Configuration of Residential Area and Vector Populations on Dengue Incidence Patterns in an Individual-Level Transmission Model
Q99240509The RNA secondary structural variation in the cyclization elements of the dengue genome and the possible implications in pathogenicity
Q39088502The Role and Function of Fcγ Receptors on Myeloid Cells
Q33817714The Role of Heterotypic DENV-specific CD8+T Lymphocytes in an Immunocompetent Mouse Model of Secondary Dengue Virus Infection
Q36217775The Significance of Prolonged and Saddleback Fever in Hospitalised Adult Dengue
Q35427943The basic reproduction number R0 and effectiveness of reactive interventions during dengue epidemics: the 2002 dengue outbreak in Easter Island, Chile.
Q56916580The battle between infection and host immune responses of dengue virus and its implication in dengue disease pathogenesis
Q35594746The burden of dengue and chikungunya worldwide: implications for the southern United States and California
Q24288879The changing epidemiology of dengue in China, 1990-2014: a descriptive analysis of 25 years of nationwide surveillance data
Q28250383The complexity of antibody-dependent enhancement of dengue virus infection
Q34048432The correlation between the presence of viremia and clinical severity in patients with enterovirus 71 infection: a multi-center cohort study
Q42987133The dengue human challenge model: has the time come to accept this challenge?
Q39540120The dengue virus conceals double-stranded RNA in the intracellular membrane to escape from an interferon response.
Q38179175The dengue virus non-structural 1 protein: risks and benefits
Q28478345The early clinical features of dengue in adults: challenges for early clinical diagnosis
Q40109065The effect of Wolbachia on dengue dynamics in the presence of two serotypes of dengue: symmetric and asymmetric epidemiological characteristics
Q33680283The effects of tertiary and quaternary infections on the epidemiology of dengue
Q34980736The future of dengue vaccines
Q34903764The history and evolution of human dengue emergence
Q40205673The human dengue challenge experience at the Walter Reed Army Institute of Research
Q36132065The impact of transgenic mosquitoes on dengue virulence to humans and mosquitoes
Q36612659The importance of hematopoietic progenitor cells in dengue.
Q44170022The introduction of dengue follows transportation infrastructure changes in the state of Acre, Brazil: A network-based analysis.
Q34542621The native Wolbachia symbionts limit transmission of dengue virus in Aedes albopictus
Q37904027The pathogenesis of dengue
Q38284671The relevance of dengue virus genotypes surveillance at country level before vaccine approval
Q33954195The role of climate variability and change in the transmission dynamics and geographic distribution of dengue
Q37713190The role of endothelial activation in dengue hemorrhagic fever and hantavirus pulmonary syndrome
Q35496004The role of pre-existing cross-reactive antibodies in determining the efficacy of vaccination in humans: study protocol for a randomized controlled trial
Q40568715The seasonal pattern of dengue in endemic areas: mathematical models of mechanisms
Q26700076The tortoise or the hare? Impacts of within-host dynamics on transmission success of arthropod-borne viruses
Q35069160The type-specific neutralizing antibody response elicited by a dengue vaccine candidate is focused on two amino acids of the envelope protein
Q34431491Therapeutics for dengue: recommendations for design and conduct of early-phase clinical trials
Q22305635Threat of dengue to blood safety in dengue-endemic countries
Q50052067Tick-Borne Encephalitis Virus Vaccine-Induced Human Antibodies Mediate Negligible Enhancement of Zika Virus Infection InVitro and in a Mouse Model
Q27469955Tick-Borne Langat/Mosquito-Borne Dengue Flavivirus Chimera, a Candidate Live Attenuated Vaccine for Protection against Disease Caused by Members of the Tick-Borne Encephalitis Virus Complex: Evaluation in Rhesus Monkeys and in Mosquitoes
Q28266913Traitors of the immune system-enhancing antibodies in HIV infection: their possible implication in HIV vaccine development
Q27468674Transcriptome meta-analysis reveals a dysregulation in extra cellular matrix and cell junction associated gene signatures during Dengue virus infection
Q50117666Transcytosis Involvement in Transport System and Endothelial Permeability of Vascular Leakage during Dengue Virus Infection
Q34147626Transient CD4/CD8 ratio inversion and aberrant immune activation during dengue virus infection
Q55333503Transmission-clearance trade-offs indicate that dengue virulence evolution depends on epidemiological context.
Q35876653Travel-related dengue virus infection, The Netherlands, 2006-2007.
Q34787775Treatment of AG129 mice with antisense morpholino oligomers increases survival time following challenge with dengue 2 virus.
Q37047163Trends in patterns of dengue transmission over 4 years in a pediatric cohort study in Nicaragua
Q38540058Trials and tribulations on the path to developing a dengue vaccine
Q39565037Under-recognition and reporting of dengue in Cambodia: a capture-recapture analysis of the National Dengue Surveillance System
Q94461357Under-the-Radar Dengue Virus Infections in Natural Populations of Aedes aegypti Mosquitoes
Q39653165Unfolded protein response (UPR) gene expression during antibody-dependent enhanced infection of cultured monocytes correlates with dengue disease severity
Q30409538Unusual dengue virus 3 epidemic in Nicaragua, 2009
Q39593503Update on dengue: epidemiology, virus evolution, antiviral drugs, and vaccine development
Q37132070Use of a Rapid Test for Diagnosis of Dengue during Suspected Dengue Outbreaks in Resource-Limited Regions
Q65054977Using Macaques to Address Critical Questions in Zika Virus Research.
Q40457125Using dimension reduction to improve outbreak predictability of multistrain diseases.
Q33586742Utility of warning signs in guiding admission and predicting severe disease in adult dengue
Q37184768Vaccination of volunteers with low-dose, live-attenuated, dengue viruses leads to serotype-specific immunologic and virologic profiles
Q37330748Vaccine-induced enhancement of viral infections.
Q36161353Validation and Application of a Commercial Quantitative Real-Time Reverse Transcriptase-PCR Assay in Investigation of a Large Dengue Virus Outbreak in Southern Taiwan
Q35141237Validation of an internally controlled one-step real-time multiplex RT-PCR assay for the detection and quantitation of dengue virus RNA in plasma
Q36213311Variation in inflammatory/regulatory cytokines in secondary, tertiary, and quaternary challenges with dengue virus
Q33910950Variation in vector competence for dengue viruses does not depend on mosquito midgut binding affinity.
Q33413903Vascular events in viral hemorrhagic fevers: a comparative study of dengue and hantaviruses
Q40303277Vascular leakage in severe dengue virus infections: a potential role for the nonstructural viral protein NS1 and complement
Q62485177Vector-borne transmission and evolution of Zika virus
Q33652446Vertical transmission of Key West dengue-1 virus by Aedes aegypti and Aedes albopictus (Diptera: Culicidae) mosquitoes from Florida
Q39629453Viral entry inhibitors block dengue antibody-dependent enhancement in vitro
Q36082908Viral kinetics of primary dengue virus infection in non-human primates: a systematic review and individual pooled analysis
Q35656099Viral resistance of MOGS-CDG patients implies a broad-spectrum strategy against acute virus infections
Q60046445Viral-Induced Enhanced Disease Illness
Q26746890Viremia and Clinical Presentation in Nicaraguan Patients Infected with Zika Virus, Chikungunya Virus, and Dengue Virus
Q40267017Viremic profiles in asymptomatic and symptomatic chikungunya fever: a blood transfusion threat?
Q27472941Virus Replication and Cytokine Production in Dengue Virus-Infected Human B Lymphocytes
Q40222559Virus antibody dynamics in primary and secondary dengue infections
Q27478050Virus-Induced Decline in Soluble Vascular Endothelial Growth Receptor 2 Is Associated with Plasma Leakage in Dengue Hemorrhagic Fever
Q34675123Virus-specific differences in rates of disease during the 2010 Dengue epidemic in Puerto Rico
Q47232816Vivo-morpholino oligomers strongly inhibit dengue virus replication and production.
Q57168259What Does the Future Hold for Yellow Fever Virus? (II)
Q40047862Which Dengue Vaccine Approach Is the Most Promising, and Should We Be Concerned about Enhanced Disease after Vaccination? The Risks of Incomplete Immunity to Dengue Virus Revealed by Vaccination
Q38947779Within-host viral dynamics of dengue serotype 1 infection
Q92647408Yellow fever control: current epidemiology and vaccination strategies

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