Regulation of NAB2 mRNA 3'-end formation requires the core exosome and the Trf4p component of the TRAMP complex

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Regulation of NAB2 mRNA 3'-end formation requires the core exosome and the Trf4p component of the TRAMP complex is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1261/RNA.709609
P8608Fatcat IDrelease_hech2gm7vfbuxntq2i7uzl2gxa
P932PMC publication ID2685527
P698PubMed publication ID19369424
P5875ResearchGate publication ID24280486

P2093author name stringFeng Fang
J Scott Butler
Kelly M Roth
Joel Byam
P2860cites workA new yeast poly(A) polymerase complex involved in RNA quality controlQ21146099
AU binding proteins recruit the exosome to degrade ARE-containing mRNAsQ24291926
The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elementsQ24292126
The yin and yang of the exosomeQ24292314
Adenylation and exosome-mediated degradation of cotranscriptionally cleaved pre-messenger RNA in human cellsQ24303497
Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'Q24305376
Human 5' --> 3' exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sitesQ24317135
Contribution of domain structure to the RNA 3' end processing and degradation functions of the nuclear exosome subunit Rrp6pQ24540216
Yeast exosome mutants accumulate 3'-extended polyadenylated forms of U4 small nuclear RNA and small nucleolar RNAsQ24554352
Assembly of a processive messenger RNA polyadenylation complexQ24564750
The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleasesQ24600315
The N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosomeQ24644651
Regulation of yeast NRD1 expression by premature transcription terminationQ82684606
Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysisQ27860815
Pta1, a component of yeast CF II, is required for both cleavage and poly(A) addition of mRNA precursorQ27930178
Nab2p is required for poly(A) RNA export in Saccharomyces cerevisiae and is regulated by arginine methylation via Hmt1pQ27931019
Identification of a regulated pathway for nuclear pre-mRNA turnover.Q27931532
Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymeraseQ27932117
Contributions of Trf4p- and Trf5p-dependent polyadenylation to the processing and degradative functions of the yeast nuclear exosomeQ27932187
Polyadenylation of rRNA in Saccharomyces cerevisiae.Q27932222
RNA degradation by the exosome is promoted by a nuclear polyadenylation complexQ27932438
Quality control of mRNA 3'-end processing is linked to the nuclear exosomeQ27932977
Rrp6p, the yeast homologue of the human PM-Scl 100-kDa autoantigen, is essential for efficient 5.8 S rRNA 3' end formationQ27933100
Exploration of essential gene functions via titratable promoter allelesQ27933619
Nrd1 interacts with the nuclear exosome for 3' processing of RNA polymerase II transcriptsQ27933675
A nuclear 3'-5' exonuclease involved in mRNA degradation interacts with Poly(A) polymerase and the hnRNA protein Npl3pQ27934140
The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complexQ27934144
The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II.Q27934493
Dual requirement for yeast hnRNP Nab2p in mRNA poly(A) tail length control and nuclear exportQ27934522
Nuclear surveillance and degradation of hypomodified initiator tRNAMet in S. cerevisiaeQ27934543
The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities.Q27934866
NAB2: a yeast nuclear polyadenylated RNA-binding protein essential for cell viabilityQ27934906
Rrp47p is an exosome-associated protein required for the 3' processing of stable RNAs.Q27935348
Yeast Trf5p is a nuclear poly(A) polymeraseQ27935421
A single subunit, Dis3, is essentially responsible for yeast exosome core activityQ27935552
Nuclear RNA surveillance in Saccharomyces cerevisiae: Trf4p-dependent polyadenylation of nascent hypomethylated tRNA and an aberrant form of 5S rRNA.Q27936202
5-fluorouracil enhances exosome-dependent accumulation of polyadenylated rRNAsQ27936402
Functional dissection of the zinc finger and flanking domains of the Yth1 cleavage/polyadenylation factorQ27937362
A panoramic view of yeast noncoding RNA processingQ27937560
Polyadenylation linked to transcription termination directs the processing of snoRNA precursors in yeastQ27937994
Interactions between mRNA export commitment, 3'-end quality control, and nuclear degradationQ27938985
Dob1p (Mtr4p) is a putative ATP-dependent RNA helicase required for the 3' end formation of 5.8S rRNA in Saccharomyces cerevisiaeQ27939006
Nuclear retention of unspliced mRNAs in yeast is mediated by perinuclear Mlp1.Q27939910
Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activitiesQ28207318
The exosome and the proteasome: nano-compartments for degradationQ28241383
RNA-quality control by the exosomeQ28251052
Precision and functional specificity in mRNA decayQ29618689
A history of poly A sequences: from formation to factors to functionQ33960046
RNA polymerase III defects suppress a conditional-lethal poly(A) polymerase mutation in Saccharomyces cerevisiae.Q33967897
Poly(A) tail length control is caused by termination of processive synthesis.Q34059279
Functional link between the mammalian exosome and mRNA decappingQ34105440
Nuclear export of RNA.Q34364012
Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factorsQ34419716
Mechanism of a genetic glissando: structural biology of indel mutations.Q34503186
Recognition of polyadenylation sites in yeast pre-mRNAs by cleavage and polyadenylation factorQ34770170
Polyadenylation: a tail of two complexes.Q35033251
Early formation of mRNP: license for export or quality control?Q35137961
Degradation of normal mRNA in the nucleus of Saccharomyces cerevisiaeQ35169986
Depletion of the yeast nuclear exosome subunit Rrp6 results in accumulation of polyadenylated RNAs in a discrete domain within the nucleolusQ35856993
Connections between mRNA 3' end processing and transcription terminationQ36131487
Process or perish: quality control in mRNA biogenesisQ36149583
Messenger RNA deadenylylation precedes decapping in mammalian cellsQ36153241
3'-end-forming signals of yeast mRNA.Q36555679
PCF11 encodes a third protein component of yeast cleavage and polyadenylation factor I.Q36565604
RNA processing in vitro produces mature 3' ends of a variety of Saccharomyces cerevisiae mRNAsQ36710092
Conditional defect in mRNA 3' end processing caused by a mutation in the gene for poly(A) polymeraseQ36819714
Reconstitution of RNA exosomes from human and Saccharomyces cerevisiae cloning, expression, purification, and activity assays.Q37412496
The mRNA encoding the yeast ARE-binding protein Cth2 is generated by a novel 3' processing pathwayQ38621829
The role of nuclear cap binding protein Cbc1p of yeast in mRNA termination and degradationQ39452112
A nuclear surveillance pathway for mRNAs with defective polyadenylation.Q39613458
Taq DNA polymerase slippage mutation rates measured by PCR and quasi-likelihood analysis: (CA/GT)n and (A/T)n microsatellitesQ39731447
The nuclear exosome contributes to autogenous control of NAB2 mRNA levelsQ41098311
Aberrant mRNAs with extended 3' UTRs are substrates for rapid degradation by mRNA surveillanceQ41899506
Processing of 3'-extended read-through transcripts by the exosome can generate functional mRNAs.Q44042962
Domain analysis of the Saccharomyces cerevisiae heterogeneous nuclear ribonucleoprotein, Nab2p. Dissecting the requirements for Nab2p-facilitated poly(A) RNA exportQ44259025
A novel poly(A)-binding protein acts as a specificity factor in the second phase of messenger RNA polyadenylationQ45284501
Yeast mRNA Poly(A) tail length control can be reconstituted in vitro in the absence of Pab1p-dependent Poly(A) nuclease activity.Q53675884
Inhibition of translational initiation in Saccharomyces cerevisiae by secondary structure: the roles of the stability and position of stem-loops in the mRNA leaderQ70511704
Efficient translation of poly(A)-deficient mRNAs in Saccharomyces cerevisiaeQ72801099
Analysis of poly(A) tail lengths by PCR: the PAT assayQ73151841
Assaying the polyadenylation state of mRNAsQ74602849
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectATP-dependent RNA helicase MTR4 YJL050WQ27548544
Non-canonical poly(A) polymerase PAP2 YOL115WQ27549284
Exosome nuclease subunit RRP6 YOR001WQ27551691
Exosome non-catalytic core subunit RRP43 YCR035CQ27551845
Exosome non-catalytic core subunit RRP46 YGR095CQ27552269
P304page(s)1045-58
P577publication date2009-06-01
P1433published inRNAQ7277164
P1476titleRegulation of NAB2 mRNA 3'-end formation requires the core exosome and the Trf4p component of the TRAMP complex
P478volume15

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cites work (P2860)
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Q42182202The yeast RPL9B gene is regulated by modulation between two modes of transcription termination
Q26851853Threading the barrel of the RNA exosome
Q37982068Yeast nuclear RNA processing

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