scholarly article | Q13442814 |
P50 | author | Trey Ideker | Q16335202 |
Michael-Christopher Keogh | Q28324309 | ||
Nevan Krogan | Q28450952 | ||
Sean R Collins | Q37393509 | ||
Gerard Cagney | Q37393538 | ||
Pedro Beltrao | Q41044831 | ||
J Peter Svensson | Q41049883 | ||
Colm J. Ryan | Q55143837 | ||
Padraig Cunningham | Q57418766 | ||
Joseph I Kliegman | Q58810238 | ||
P2093 | author name string | Hyun-Soo Kim | |
Michael Shales | |||
Kevan M Shokat | |||
Christine Guthrie | |||
Zongtian Tong | |||
Chao Tang | |||
Winfried Edelmann | |||
Hong Qu | |||
Assen Roguev | |||
Derek Greene | |||
Elena Tosti | |||
Peter J Espenshade | |||
Lingli Jiang | |||
Jiewei Xu | |||
Dwight Kuo | |||
Harlizawati Jahari | |||
Kristin Patrick | |||
P2860 | cites work | The evolutionary origin of orphan genes | Q22122002 |
Epistasis--the essential role of gene interactions in the structure and evolution of genetic systems | Q22122008 | ||
Finding the missing heritability of complex diseases | Q22122198 | ||
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling | Q24306275 | ||
Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids | Q24306330 | ||
pICln inhibits snRNP biogenesis by binding core spliceosomal proteins | Q24517638 | ||
Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores | Q24534626 | ||
Functional organization of the S. cerevisiae phosphorylation network | Q24634340 | ||
High-quality binary protein interaction map of the yeast interactome network | Q24651397 | ||
A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast | Q24670484 | ||
A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin | Q24801790 | ||
Where does fission yeast sit on the tree of life? | Q24804391 | ||
Ribonuclease activity of Dis3 is required for mitotic progression and provides a possible link between heterochromatin and kinetochore function | Q27303046 | ||
Functional profiling of the Saccharomyces cerevisiae genome | Q27860544 | ||
ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex | Q27929959 | ||
The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program | Q27931213 | ||
A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria | Q27931884 | ||
Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription | Q27932406 | ||
A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing | Q27932638 | ||
The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex | Q27932742 | ||
A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1. | Q27933672 | ||
Global mapping of the yeast genetic interaction network | Q27934987 | ||
Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex | Q27935315 | ||
Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile | Q27935813 | ||
A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking | Q27937526 | ||
Degradation of misfolded endoplasmic reticulum glycoproteins in Saccharomyces cerevisiae is determined by a specific oligosaccharide structure | Q27938571 | ||
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae | Q27938796 | ||
Functional discovery via a compendium of expression profiles | Q27938962 | ||
Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes | Q27939264 | ||
The genetic landscape of a cell | Q28131628 | ||
The BioGRID Interaction Database: 2011 update | Q28298160 | ||
Genetic interaction maps in Escherichia coli reveal functional crosstalk among cell envelope biogenesis pathways | Q28478052 | ||
The mystery of missing heritability: Genetic interactions create phantom heritability | Q28732355 | ||
A gene-coexpression network for global discovery of conserved genetic modules | Q29614451 | ||
Genome-wide association studies for common diseases and complex traits | Q29615822 | ||
Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map | Q29618911 | ||
The DASH complex and Klp5/Klp6 kinesin coordinate bipolar chromosome attachment in fission yeast | Q30476087 | ||
HOPS interacts with Apl5 at the vacuole membrane and is required for consumption of AP-3 transport vesicles | Q30491341 | ||
A strategy for extracting and analyzing large-scale quantitative epistatic interaction data | Q31049488 | ||
Functional maps of protein complexes from quantitative genetic interaction data | Q31153034 | ||
Genome-wide association data reveal a global map of genetic interactions among protein complexes | Q33521286 | ||
Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe. | Q33579032 | ||
Systematic interpretation of genetic interactions using protein networks | Q33622989 | ||
Conserved patterns of protein interaction in multiple species | Q33837704 | ||
Improved functional overview of protein complexes using inferred epistatic relationships. | Q33909267 | ||
PomBase: a comprehensive online resource for fission yeast | Q34228886 | ||
Rewiring of genetic networks in response to DNA damage. | Q34425692 | ||
The evolutionary analysis of "orphans" from the Drosophila genome identifies rapidly diverging and incorrectly annotated genes | Q34613438 | ||
Novel genes exhibit distinct patterns of function acquisition and network integration | Q34613793 | ||
Modelling genotype-phenotype relationships and human disease with genetic interaction networks | Q34621400 | ||
High-throughput genetic interaction mapping in the fission yeast Schizosaccharomyces pombe | Q34692755 | ||
eSGA: E. coli synthetic genetic array analysis | Q34803849 | ||
Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes | Q34860078 | ||
Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. | Q34874112 | ||
High-throughput, quantitative analyses of genetic interactions in E. coli | Q34927322 | ||
Detecting gene-gene interactions that underlie human diseases | Q34980492 | ||
Quantitative analysis of fitness and genetic interactions in yeast on a genome scale | Q35051808 | ||
The Ubiquitous Nature of Epistasis in Determining Susceptibility to Common Human Diseases | Q35582337 | ||
Transcriptional regulation of protein complexes within and across species | Q35611673 | ||
Yeast sterol regulatory element-binding protein (SREBP) cleavage requires Cdc48 and Dsc5, a ubiquitin regulatory X domain-containing subunit of the Golgi Dsc E3 ligase | Q35643838 | ||
Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK | Q35749976 | ||
Conserved pathways within bacteria and yeast as revealed by global protein network alignment | Q36160907 | ||
Modeling cellular machinery through biological network comparison | Q36443509 | ||
A global analysis of genetic interactions in Caenorhabditis elegans | Q36640170 | ||
The TSC1-TSC2 complex is required for proper activation of mTOR complex 2 | Q36710799 | ||
The S. pombe SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8. | Q36995417 | ||
Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment | Q37038553 | ||
Exploiting the proteome to improve the genome-wide genetic analysis of epistasis in common human diseases | Q37190495 | ||
Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. | Q37365634 | ||
Epistatic relationships reveal the functional organization of yeast transcription factors | Q38339973 | ||
Mapping of signaling networks through synthetic genetic interaction analysis by RNAi | Q39580460 | ||
Optimal stepwise experimental design for pairwise functional interaction studies | Q41346415 | ||
Quantitative genetic interactions reveal biological modularity | Q41830607 | ||
Quantitative genetic interaction mapping using the E-MAP approach | Q42407989 | ||
Violations of robustness trade-offs | Q42618981 | ||
Two kinesin-like Kin I family proteins in fission yeast regulate the establishment of metaphase and the onset of anaphase A. | Q48307683 | ||
Epistasis: too often neglected in complex trait studies? | Q48541812 | ||
LAMMER kinase Kic1 is involved in pre-mRNA processing. | Q50516987 | ||
Vacuolar protein sorting receptor in Schizosaccharomyces pombe. | Q50733234 | ||
Evolutionary plasticity of genetic interaction networks | Q55554510 | ||
Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways | Q55554520 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell biology | Q7141 |
Ubiquitin-protein ligase TUL1 YKL034W | Q27547589 | ||
Dsc2p YOL073C | Q27548181 | ||
Dsc3p YOR223W | Q27550208 | ||
Ubx3p YDL091C | Q27551361 | ||
P304 | page(s) | 691-704 | |
P577 | publication date | 2012-06-08 | |
P1433 | published in | Molecular Cell | Q3319468 |
P1476 | title | Hierarchical modularity and the evolution of genetic interactomes across species. | |
P478 | volume | 46 |
Q46002486 | A Compendium of Co-regulated Protein Complexes in Breast Cancer Reveals Collateral Loss Events. |
Q38838357 | A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy. |
Q37636592 | A Pil1-Sle1-Syj1-Tax4 functional pathway links eisosomes with PI(4,5)P2 regulation |
Q89831441 | A Quantitative Genetic Interaction Map of HIV Infection |
Q64120456 | A genetic approach to study polyubiquitination in Saccharomyces cerevisiae |
Q41971229 | A genetic screen for functional partners of condensin in fission yeast. |
Q34466080 | A map of directional genetic interactions in a metazoan cell |
Q34441358 | A systematic genetic screen identifies new factors influencing centromeric heterochromatin integrity in fission yeast |
Q34581520 | A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility |
Q38955424 | A tool named Iris for versatile high-throughput phenotyping in microorganisms. |
Q34036638 | All or nothing: protein complexes flip essentiality between distantly related eukaryotes. |
Q26786228 | An Ancient Yeast for Young Geneticists: A Primer on the Schizosaccharomyces pombe Model System |
Q38563463 | Bacterial protein networks: properties and functions |
Q33742644 | Broad metabolic sensitivity profiling of a prototrophic yeast deletion collection |
Q38622324 | Cell-based screens and phenomics with fission yeast. |
Q33557346 | Chemical genetics of rapamycin-insensitive TORC2 in S. cerevisiae. |
Q35555201 | Chemical genomics approach to identify genes associated with sensitivity to rapamycin in the fission yeast Schizosaccharomyces pombe. |
Q34850230 | Comparison of profile similarity measures for genetic interaction networks |
Q35006955 | Conserved abundance and topological features in chromatin-remodeling protein interaction networks |
Q36998501 | Conserved and Diverged Functions of the Calcineurin-Activated Prz1 Transcription Factor in Fission Yeast |
Q37184407 | Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways |
Q28550285 | Dbl2 Regulates Rad51 and DNA Joint Molecule Metabolism to Ensure Proper Meiotic Chromosome Segregation |
Q38076910 | Design principles of regulatory networks: searching for the molecular algorithms of the cell |
Q35086186 | Development of ultra-high-density screening tools for microbial "omics". |
Q40366064 | Differential genetic interactions of yeast stress response MAPK pathways |
Q30663150 | Dissection of DNA damage responses using multiconditional genetic interaction maps |
Q62673364 | Drug combinations: a strategy to extend the life of antibiotics in the 21st century |
Q36658548 | Epigenetic epistatic interactions constrain the evolution of gene expression |
Q37157035 | Evolution of a G protein-coupled receptor response by mutations in regulatory network interactions |
Q43079790 | Evolution. Systematic humanization of yeast genes reveals conserved functions and genetic modularity |
Q34306599 | Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologous relationships in mismatch repair-deficient cancer cells |
Q41882250 | From structure to systems: high-resolution, quantitative genetic analysis of RNA polymerase II. |
Q26830798 | From systems to structure: bridging networks and mechanism |
Q36215342 | Functional characterisation of long intergenic non-coding RNAs through genetic interaction profiling in Saccharomyces cerevisiae. |
Q35583065 | Genetic Interaction Landscape Reveals Critical Requirements for Schizosaccharomyces pombe Brc1 in DNA Damage Response Mutants |
Q60302058 | Genetic analysis reveals functions of atypical polyubiquitin chains |
Q90475922 | Genetic correlation network prediction of forest soil microbial functional organization |
Q42272826 | Genetic interaction analysis of point mutations enables interrogation of gene function at a residue-level resolution: exploring the applications of high-resolution genetic interaction mapping of point mutations |
Q35235099 | Genetic interaction mapping reveals a role for the SWI/SNF nucleosome remodeler in spliceosome activation in fission yeast |
Q27023184 | Genetic interaction networks: better understand to better predict |
Q35132881 | Genome-wide epistatic expression quantitative trait loci discovery in four human tissues reveals the importance of local chromosomal interactions governing gene expression. |
Q37399103 | Genotype to phenotype via network analysis |
Q38077445 | Genotype to phenotype: lessons from model organisms for human genetics |
Q55384044 | Harnessing synthetic lethality to predict the response to cancer treatment. |
Q38667267 | High-Throughput Quantitative Genetic Interaction Mapping in the Fission Yeast Schizosaccharomyces pombe. |
Q33623110 | High-resolution network biology: connecting sequence with function |
Q35105750 | High-resolution profiling of stationary-phase survival reveals yeast longevity factors and their genetic interactions. |
Q34391566 | How the nucleus copes with proteotoxic stress |
Q37671487 | Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function |
Q34468295 | Identification of candidate substrates for the Golgi Tul1 E3 ligase using quantitative diGly proteomics in yeast. |
Q92898651 | Identification of proteins associated with splicing factors Ntr1, Ntr2, Brr2 and Gpl1 in the fission yeast Schizosaccharomyces pombe |
Q30797535 | Imputing missing values for genetic interaction data |
Q64019134 | Integrating genetic and protein-protein interaction networks maps a functional wiring diagram of a cell |
Q95940288 | Integrative analysis of large-scale loss-of-function screens identifies robust cancer-associated genetic interactions |
Q26824897 | Integrative approaches for finding modular structure in biological networks |
Q36958121 | Interconnections Between RNA-Processing Pathways Revealed by a Sequencing-Based Genetic Screen for Pre-mRNA Splicing Mutants in Fission Yeast |
Q30834280 | Kinesin-8 effects on mitotic microtubule dynamics contribute to spindle function in fission yeast. |
Q36713548 | Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines |
Q36185332 | Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity |
Q42369678 | Lingering single-strand breaks trigger Rad51-independent homology-directed repair of collapsed replication forks in the polynucleotide kinase/phosphatase mutant of fission yeast |
Q64232908 | Modular epistasis and the compensatory evolution of gene deletion mutants |
Q50211661 | Native gel analysis of macromolecular protein complexes in cultured mammalian cells |
Q36238554 | Network Centrality Analysis in Fungi Reveals Complex Regulation of Lost and Gained Genes. |
Q92131450 | PS-MCL: parallel shotgun coarsened Markov clustering of protein interaction networks |
Q34923804 | Parallel profiling of fission yeast deletion mutants for proliferation and for lifespan during long-term quiescence. |
Q42425984 | Potential unsatisfiability of cyclic constraints on stochastic biological networks biases selection towards hierarchical architectures |
Q58098406 | Predicting bioprocess targets of chemical compounds through integration of chemical-genetic and genetic interactions |
Q45826942 | Predicting functional gene interactions with the hierarchical interaction score |
Q35130411 | Protein complexes in bacteria. |
Q35689663 | Quantitative Fitness Analysis Identifies exo1∆ and Other Suppressors or Enhancers of Telomere Defects in Schizosaccharomyces pombe. |
Q35204646 | Quantitative analysis of triple-mutant genetic interactions |
Q36811345 | Quantitative genetic-interaction mapping in mammalian cells |
Q35400929 | Rapid epigenetic adaptation to uncontrolled heterochromatin spreading |
Q41758914 | Rewiring of genetic networks in response to modification of genetic background |
Q35247564 | SANTA: quantifying the functional content of molecular networks |
Q43625940 | Schizosaccharomyces pombe centromere protein Mis19 links Mis16 and Mis18 to recruit CENP-A through interacting with NMD factors and the SWI/SNF complex |
Q41825385 | Set5 and Set1 cooperate to repress gene expression at telomeres and retrotransposons |
Q45141810 | Shelterin components mediate genome reorganization in response to replication stress. |
Q38783458 | Similarity analysis between chromosomes of Homo sapiens and monkeys with correlation coefficient, rank correlation coefficient and cosine similarity measures |
Q56170738 | Species-specific activity of antibacterial drug combinations |
Q41826440 | Splicing functions and global dependency on fission yeast slu7 reveal diversity in spliceosome assembly |
Q35922301 | Structural and Functional Characterization of a Caenorhabditis elegans Genetic Interaction Network within Pathways |
Q37175122 | Subunit architecture of the Golgi Dsc E3 ligase required for sterol regulatory element-binding protein (SREBP) cleavage in fission yeast |
Q89187412 | Synthetic Lethal Networks for Precision Oncology: Promises and Pitfalls |
Q57190621 | Synthetic Lethality and Cancer - Penetrance as the Major Barrier |
Q38709651 | Synthetic lethality and cancer. |
Q64082743 | Systematic analysis reveals the prevalence and principles of bypassable gene essentiality |
Q36701055 | Systematic identification and correction of annotation errors in the genetic interaction map of Saccharomyces cerevisiae |
Q35086142 | Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth. |
Q37032537 | Systematic triple-mutant analysis uncovers functional connectivity between pathways involved in chromosome regulation. |
Q30276470 | Systems level analysis of the Chlamydomonas reinhardtii metabolic network reveals variability in evolutionary co-conservation |
Q30009309 | The Cdc15 and Imp2 SH3 domains cooperatively scaffold a network of proteins that redundantly ensure efficient cell division in fission yeast |
Q37193578 | The Effect of G-ORS Along With Rice Soup in the Treatment of Acute Diarrhea in Children: A Single-Blind Randomized Controlled Trial |
Q52376069 | The INO80 chromatin remodeler sustains metabolic stability by promoting TOR signaling and regulating histone acetylation. |
Q55077869 | The contribution of non-essential Schizosaccharomyces pombe genes to fitness in response to altered nutrient supply and target of rapamycin activity. |
Q90187249 | The fission yeast FHIT homolog affects checkpoint control of proliferation and is regulated by mitochondrial electron transport |
Q37318693 | The fission yeast cell wall stress sensor-like proteins Mtl2 and Wsc1 act by turning on the GTPase Rho1p but act independently of the cell wall integrity pathway |
Q38818040 | The histone variant H2A.Z promotes splicing of weak introns. |
Q104100296 | The phosphatase inhibitor Sds23 promotes symmetric spindle positioning in fission yeast |
Q36258476 | Transient structural variations have strong effects on quantitative traits and reproductive isolation in fission yeast |
Q91011163 | Using BEAN-counter to quantify genetic interactions from multiplexed barcode sequencing experiments |
Q48042369 | Using genetic buffering relationships identified in fission yeast to reveal susceptibilities in cells lacking hamartin or tuberin function. |
Q28818537 | Widespread Genetic Incompatibilities between First-Step Mutations during Parallel Adaptation of Saccharomyces cerevisiae to a Common Environment |
Search more.