ATR homolog Mec1 controls association of DNA polymerase zeta-Rev1 complex with regions near a double-strand break

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ATR homolog Mec1 controls association of DNA polymerase zeta-Rev1 complex with regions near a double-strand break is …
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scholarly articleQ13442814

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P356DOI10.1016/J.CUB.2006.01.063
P698PubMed publication ID16546083
P5875ResearchGate publication ID7232969

P2093author name stringKatsunori Sugimoto
Yukinori Hirano
P2860cites workThe BRCT Domain Is a Phospho-Protein Binding DomainQ24298428
Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesisQ24594244
A role for Saccharomyces cerevisiae histone H2A in DNA repair.Q27930827
The 9-1-1 checkpoint clamp physically interacts with polzeta and is partially required for spontaneous polzeta-dependent mutagenesis in Saccharomyces cerevisiaeQ27931291
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1Q27938100
The DNA replication fork in eukaryotic cells.Q27939216
The DNA damage response: putting checkpoints in perspectiveQ28131713
Interaction of hREV1 with three human Y-family DNA polymerasesQ28266239
Co-localization in replication foci and interaction of human Y-family members, DNA polymerase pol eta and REVl proteinQ28283240
Roles of yeast DNA polymerases delta and zeta and of Rev1 in the bypass of abasic sitesQ28363488
Cell cycle checkpoints: preventing an identity crisisQ29547644
Eukaryotic translesion synthesis DNA polymerases: specificity of structure and functionQ29617871
Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugationQ29619155
From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repairQ29619880
Partners and pathwaysrepairing a double-strand break.Q33927291
A role for REV3 in mutagenesis during double-strand break repair in Saccharomyces cerevisiaeQ33971118
Yeast histone 2A serine 129 is essential for the efficient repair of checkpoint-blind DNA damageQ34250284
Distribution and dynamics of chromatin modification induced by a defined DNA double-strand breakQ34354650
The roles of REV3 and RAD57 in double-strand-break-repair-induced mutagenesis of Saccharomyces cerevisiaeQ34616322
Specialized DNA polymerases, cellular survival, and the genesis of mutationsQ34662609
Cellular roles of DNA polymerase zeta and Rev1 proteinQ35037431
Dial 9-1-1 for DNA damage: the Rad9-Hus1-Rad1 (9-1-1) clamp complexQ35848485
Nonhomologous end joining in yeastQ36312212
Opposing effects of ubiquitin conjugation and SUMO modification of PCNA on replicational bypass of DNA lesions in Saccharomyces cerevisiaeQ37731934
Pie1, a protein interacting with Mec1, controls cell growth and checkpoint responses in Saccharomyces cerevisiaeQ39457690
ATM-related Tel1 associates with double-strand breaks through an Xrs2-dependent mechanismQ39896119
Dual roles for DNA polymerase eta in homologous DNA recombination and translesion DNA synthesisQ40342097
Human DNA polymerase eta promotes DNA synthesis from strand invasion intermediates of homologous recombinationQ40342102
Association of Rad9 with double-strand breaks through a Mec1-dependent mechanism.Q40737039
The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damageQ41854894
Evidence for a second function for Saccharomyces cerevisiae Rev1pQ74130085
MEC1-dependent phosphorylation of Rad9p in response to DNA damageQ77231583
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectRev7p YIL139CQ27551615
Deoxycytidyl transferase YOR346WQ27552082
P304page(s)586-90
P577publication date2006-03-21
P1433published inCurrent BiologyQ1144851
P1476titleATR homolog Mec1 controls association of DNA polymerase zeta-Rev1 complex with regions near a double-strand break
P478volume16

Reverse relations

cites work (P2860)
Q35049451Analysis of the tolerance to DNA alkylating damage in MEC1 and RAD53 checkpoint mutants of Saccharomyces cerevisiae
Q35810623Cdc13 telomere capping decreases Mec1 association but does not affect Tel1 association with DNA ends
Q34244941Competition between replicative and translesion polymerases during homologous recombination repair in Drosophila
Q37187991DNA damage tolerance: a double-edged sword guarding the genome
Q41860261DNA damage tolerance: when it's OK to make mistakes
Q34729967DNA polymerase zeta (pol zeta) in higher eukaryotes
Q36021801DNA polymerase ζ generates tandem mutations in immunoglobulin variable regions
Q37084895DNA polymerases and cancer.
Q36816885Emerging links between the biological clock and the DNA damage response
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Q35696052FANCD2 and REV1 cooperate in the protection of nascent DNA strands in response to replication stress
Q34778532Fragile DNA motifs trigger mutagenesis at distant chromosomal loci in saccharomyces cerevisiae
Q42497589Genomic deletions and point mutations induced in Saccharomyces cerevisiae by the trinucleotide repeats (GAA·TTC) associated with Friedreich's ataxia
Q36891684Integrating S-phase checkpoint signaling with trans-lesion synthesis of bulky DNA adducts
Q34432676Loss of DNA polymerase zeta enhances spontaneous tumorigenesis
Q35139973Molecular chaperone Hsp90 regulates REV1-mediated mutagenesis
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Q91592913Multigenic truncation of the semaphorin-plexin pathway by a germline chromothriptic rearrangement associated with Moebius syndrome
Q36247787Mutator alleles of yeast DNA polymerase zeta.
Q37023245Novel conserved motifs in Rev1 C-terminus are required for mutagenic DNA damage tolerance
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Q28509424PTIP/Swift is required for efficient PCNA ubiquitination in response to DNA damage
Q37106800Pol zeta ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability
Q36140297Pol31 and Pol32 subunits of yeast DNA polymerase δ are also essential subunits of DNA polymerase ζ.
Q21145041Proofreading activity of DNA polymerase Pol2 mediates 3'-end processing during nonhomologous end joining in yeast
Q28118890REV1 and polymerase ζ facilitate homologous recombination repair
Q40490032REV1 is important for the ATR-Chk1 DNA damage response pathway in Xenopus egg extracts
Q89794767Regulation of the abundance of Y-family polymerases in the cell cycle of budding yeast in response to DNA damage
Q36533084Rev1 and Polzeta influence toxicity and mutagenicity of Me-lex, a sequence selective N3-adenine methylating agent.
Q31154777Ribonucleotide incorporation by yeast DNA polymerase ζ.
Q43193261Role of budding yeast Rad18 in repair of HO-induced double-strand breaks.
Q36687824Roles of DNA polymerases in replication, repair, and recombination in eukaryotes.
Q42145649Roles of exonucleases and translesion synthesis DNA polymerases during mitotic gap repair in yeast
Q35683489The Protein Level of Rev1, a TLS Polymerase in Fission Yeast, Is Strictly Regulated during the Cell Cycle and after DNA Damage
Q36543289The Rad53 signal transduction pathway: Replication fork stabilization, DNA repair, and adaptation
Q40423246The Translesion Polymerase ζ Has Roles Dependent on and Independent of the Nuclease MUS81 and the Helicase RECQ4A in DNA Damage Repair in Arabidopsis.
Q33257520The fidelity of DNA synthesis by yeast DNA polymerase zeta alone and with accessory proteins.
Q39642875Trans-Lesion DNA Polymerases May Be Involved in Yeast Meiosis
Q38086224Translesion DNA synthesis and mutagenesis in eukaryotes

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