Functional cooperation of Dam1, Ipl1, and the inner centromere protein (INCENP)-related protein Sli15 during chromosome segregation

scientific article

Functional cooperation of Dam1, Ipl1, and the inner centromere protein (INCENP)-related protein Sli15 during chromosome segregation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1083/JCB.200105029
P932PMC publication ID2150868
P698PubMed publication ID11724818
P5875ResearchGate publication ID11630643

P2093author name stringG Barnes
J Kang
C S Chan
S Velmurugan
I M Cheeseman
G Kallstrom
P2860cites workMitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodesQ24290197
The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregationQ24290969
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinasesQ24319848
Cdc20 associates with the kinase aurora2/AikQ24648501
Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferaseQ27860571
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiaeQ27860636
Molecular analysis of kinetochore-microtubule attachment in budding yeast.Q27931971
Budding yeast centromere composition and assembly as revealed by in vivo cross-linkingQ27933562
The budding yeast proteins Spc24p and Spc25p interact with Ndc80p and Nuf2p at the kinetochore and are important for kinetochore clustering and checkpoint controlQ27934353
Isolation and characterization of chromosome-gain and increase-in-ploidy mutants in yeast.Q27934486
Sli15 associates with the ipl1 protein kinase to promote proper chromosome segregation in Saccharomyces cerevisiaeQ27935777
Regulation of chromosome segregation by Glc8p, a structural homolog of mammalian inhibitor 2 that functions as both an activator and an inhibitor of yeast protein phosphatase 1Q27937062
The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeastQ27937537
Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeastQ28131604
Drosophila aurora B kinase is required for histone H3 phosphorylation and condensin recruitment during chromosome condensation and to organize the central spindle during cytokinesisQ28206511
A dominant mutant of inner centromere protein (INCENP), a chromosomal protein, disrupts prometaphase congression and cytokinesisQ28263939
Vectors for the inducible overexpression of glutathione S-transferase fusion proteins in yeastQ29618547
The Aurora/Ipl1p kinase family: regulators of chromosome segregation and cytokinesis.Q30323011
Aurora/Ipl1p-related kinases, a new oncogenic family of mitotic serine-threonine kinasesQ33752816
Mapping Polycomb-repressed domains in the bithorax complex using in vivo formaldehyde cross-linked chromatinQ34321793
The inner centromere protein (INCENP) antigens: movement from inner centromere to midbody during mitosisQ36217808
Molecular analysis of the INCENPs (inner centromere proteins): separate domains are required for association with microtubules during interphase and with the central spindle during anaphase.Q36233402
Saccharomyces cerevisiae Duo1p and Dam1p, novel proteins involved in mitotic spindle functionQ36255914
Mitotic spindle integrity and kinetochore function linked by the Duo1p/Dam1p complexQ36370029
Type 1 protein phosphatase acts in opposition to IpL1 protein kinase in regulating yeast chromosome segregationQ36657172
Yeast Dam1p is required to maintain spindle integrity during mitosis and interacts with the Mps1p kinaseQ36895837
Identification of a novel microtubule binding and assembly domain in the developmentally regulated inter-repeat region of tau.Q38310577
Mis6, a fission yeast inner centromere protein, acts during G1/S and forms specialized chromatin required for equal segregationQ48047339
INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow.Q52541041
Incenp and an Aurora-like kinase form a complex essential for chromosome segregation and efficient completion of cytokinesisQ61455361
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
cooperationQ380962
Sli15p YBR156CQ27551297
Aurora kinase YPL209CQ27552652
P304page(s)763-74
P577publication date2001-11-26
P1433published inJournal of Cell BiologyQ1524550
P1476titleFunctional cooperation of Dam1, Ipl1, and the inner centromere protein (INCENP)-related protein Sli15 during chromosome segregation
P478volume155

Reverse relations

cites work (P2860)
Q36491412A Bir1-Sli15 complex connects centromeres to microtubules and is required to sense kinetochore tension
Q30480133A Bir1p Sli15p kinetochore passenger complex regulates septin organization during anaphase
Q38654369A Functional Link Between Bir1 and the Saccharomyces cerevisiae Ctf19 Kinetochore Complex Revealed Through Quantitative Fitness Analysis.
Q91866560A Gradient in Metaphase Tension Leads to a Scaled Cellular Response in Mitosis
Q26995347Aurora B hyperactivation by Bub1 overexpression promotes chromosome missegregation
Q30440998Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly
Q30309901Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation
Q24307822Aurora B regulates MCAK at the mitotic centromere
Q36210257Aurora kinases: shining lights on the therapeutic horizon?
Q34361195Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells
Q44727121Autophosphorylation of a newly identified site of Aurora-B is indispensable for cytokinesis
Q34621622Beyond the ABCs of CKC and SCC. Do centromeres orchestrate sister chromatid cohesion or vice versa?
Q34688467Bi-orienting chromosomes on the mitotic spindle.
Q37078661Bir1 is required for the tension checkpoint
Q24676678Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle
Q35047487Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation
Q34888095Bub1, Sgo1, and Mps1 mediate a distinct pathway for chromosome biorientation in budding yeast
Q42120394CSC-1: a subunit of the Aurora B kinase complex that binds to the survivin-like protein BIR-1 and the incenp-like protein ICP-1
Q33603192Catch and release: how do kinetochores hook the right microtubules during mitosis?
Q99569148Cdk1 Phosphorylation of the Dam1 Complex Strengthens Kinetochore-Microtubule Attachments
Q26998631Cell division: control of the chromosomal passenger complex in time and space
Q56866576Centromere and Kinetochore: Essential Components for Chromosome Segregation
Q42745909Chromosomal enrichment and activation of the aurora B pathway are coupled to spatially regulate spindle assembly
Q29620468Chromosomal passengers: conducting cell division
Q36129371Chromosome bi-orientation on the mitotic spindle
Q34825158Chromosome passenger complexes control anaphase duration and spindle elongation via a kinesin-5 brake.
Q35646477Cleavage furrow positioning
Q35805293Cohesin release is required for sister chromatid resolution, but not for condensin-mediated compaction, at the onset of mitosis
Q34400059Combining genetic perturbations and proteomics to examine kinase-phosphatase networks in Drosophila embryos
Q30476703Contractile ring-independent localization of DdINCENP, a protein important for spindle stability and cytokinesis
Q35632434Correction of microtubule-kinetochore attachment errors: mechanisms and role in tumor suppression
Q34206167Cryo-EM studies of microtubule structural intermediates and kinetochore-microtubule interactions
Q30490452Cyclin B destruction triggers changes in kinetochore behavior essential for successful anaphase
Q34158944Dam1 is the right one: phosphoregulation of kinetochore biorientation
Q27936318Deficient sumoylation of yeast 2-micron plasmid proteins Rep1 and Rep2 associated with their loss from the plasmid-partitioning locus and impaired plasmid inheritance.
Q28277516Direct association with inner centromere protein (INCENP) activates the novel chromosomal passenger protein, Aurora-C
Q47071818Drosophila Incenp is required for cytokinesis and asymmetric cell division during development of the nervous system
Q34000717Dual detection of chromosomes and microtubules by the chromosomal passenger complex drives spindle assembly
Q27937233Efficient chromosome biorientation and the tension checkpoint in Saccharomyces cerevisiae both require Bir1.
Q37256638Emerging roles for centromeres in meiosis I chromosome segregation
Q90131687Enrichment of Aurora B kinase at the inner kinetochore controls outer kinetochore assembly
Q35936918Essential tension and constructive destruction: the spindle checkpoint and its regulatory links with mitotic exit
Q24682520Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis
Q35123861Function and regulation of Aurora/Ipl1p kinase family in cell division
Q27931042Glc7/protein phosphatase 1 regulatory subunits can oppose the Ipl1/aurora protein kinase by redistributing Glc7.
Q28776472Global control of histone modification by the anaphase-promoting complex
Q47072479INCENP and Aurora B promote meiotic sister chromatid cohesion through localization of the Shugoshin MEI-S332 in Drosophila
Q24652456Implication of a novel multiprotein Dam1p complex in outer kinetochore function
Q40431638In vivo requirements for rDNA chromosome condensation reveal two cell-cycle-regulated pathways for mitotic chromosome folding
Q34602644Integrating functions at the kinetochore
Q35102428Ipl1/Aurora-dependent phosphorylation of Sli15/INCENP regulates CPC-spindle interaction to ensure proper microtubule dynamics
Q27939198Ipl1p-dependent phosphorylation of Mad3p is required for the spindle checkpoint response to lack of tension at kinetochores.
Q41959848Kinase signaling in the spindle checkpoint
Q52347318Kinesins relocalize the chromosomal passenger complex to the midzone for spindle disassembly.
Q36337950Kinetochore capture and bi-orientation on the mitotic spindle.
Q27934784Kinetochore protein interactions and their regulation by the Aurora kinase Ipl1p
Q34237039Laterally attached kinetochores recruit the checkpoint protein Bub1, but satisfy the spindle checkpoint
Q35012127Microfilaments and microtubules: the news from yeast.
Q34368625Microtubule-associated proteins and their essential roles during mitosis.
Q41909947Microtubules accelerate the kinase activity of Aurora-B by a reduction in dimensionality
Q74083645Mitosis: aurora gives chromosomes a healthy stretch
Q28748324Mitotic spindle disassembly occurs via distinct subprocesses driven by the anaphase-promoting complex, Aurora B kinase, and kinesin-8
Q27929767Mps1 phosphorylation of Dam1 couples kinetochores to microtubule plus ends at metaphase
Q34602318Mutations in the chromosomal passenger complex and the condensin complex differentially affect synaptonemal complex disassembly and metaphase I configuration in Drosophila female meiosis.
Q27934475Nbl1p: a Borealin/Dasra/CSC-1-like protein essential for Aurora/Ipl1 complex function and integrity in Saccharomyces cerevisiae
Q35133597Overlapping kinetochore targets of CK2 and Aurora B kinases in mitotic regulation
Q27931713Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p
Q35099863Phosphorylation of Sli15 by Ipl1 is important for proper CPC localization and chromosome stability in Saccharomyces cerevisiae.
Q35758017Phosphorylation of the carboxyl terminus of inner centromere protein (INCENP) by the Aurora B Kinase stimulates Aurora B kinase activity
Q37095418Phosphorylation regulates kinase and microtubule binding activities of the budding yeast chromosomal passenger complex in vitro
Q36890081Regulation of Sli15/INCENP, kinetochore, and Cdc14 phosphatase functions by the ribosome biogenesis protein Utp7
Q52716073Regulation of kinetochore configuration during mitosis.
Q36710819Regulation of the Aurora B chromosome passenger protein complex during oocyte maturation in Xenopus laevis
Q81471169Rings around kinetochore microtubules in yeast
Q34629172Sensing centromere tension: Aurora B and the regulation of kinetochore function
Q44647087Separase Regulates INCENP-Aurora B Anaphase Spindle Function Through Cdc14
Q34603024Simple centromere, complex kinetochore: linking spindle microtubules and centromeric DNA in budding yeast
Q24298466Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together
Q37411553Structure-function insights into the yeast Dam1 kinetochore complex
Q36451335Suppressors of ipl1-2 in components of a Glc7 phosphatase complex, Cdc48 AAA ATPase, TORC1, and the kinetochore
Q58079220Survivin regulates chromosome segregation by modulating the phosphorylation of Aurora B during porcine oocyte meiosis
Q36332561Tetraploidy/aneuploidy and stem cells in cancer promotion: The role of chromosome passenger proteins
Q36325654The 2 micron plasmid purloins the yeast cohesin complex: a mechanism for coupling plasmid partitioning and chromosome segregation?
Q26777130The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling
Q30565377The Aurora B kinase in Trypanosoma brucei undergoes post-translational modifications and is targeted to various subcellular locations through binding to TbCPC1.
Q27316300The Aurora Kinase in Trypanosoma brucei plays distinctive roles in metaphase-anaphase transition and cytokinetic initiation
Q37122543The C. elegans Tousled-like kinase contributes to chromosome segregation as a substrate and regulator of the Aurora B kinase.
Q83232806The COMA complex interacts with Cse4 and positions Sli15/Ipl1 at the budding yeast inner kinetochore
Q30376716The Inner Centromere Protein (INCENP) Coil Is a Single α-Helix (SAH) Domain That Binds Directly to Microtubules and Is Important for Chromosome Passenger Complex (CPC) Localization and Function in Mitosis.
Q47253052The Ins and Outs of Aurora B Inner Centromere Localization
Q91816384The Opposing Functions of Protein Kinases and Phosphatases in Chromosome Bipolar Attachment
Q28217817The aurora B kinase AIR-2 regulates kinetochores during mitosis and is required for separation of homologous Chromosomes during meiosis
Q28213756The aurora kinase AIR-2 functions in the release of chromosome cohesion in Caenorhabditis elegans meiosis
Q27931138The budding yeast Cdc48(Shp1) complex promotes cell cycle progression by positive regulation of protein phosphatase 1 (Glc7).
Q27934497The budding yeast Ipl1/Aurora protein kinase regulates mitotic spindle disassembly
Q41399844The cell cycle as a therapeutic target against Trypanosoma brucei: Hesperadin inhibits Aurora kinase-1 and blocks mitotic progression in bloodstream forms
Q29617749The cellular geography of aurora kinases
Q36504489The chromosomal passenger complex: guiding Aurora-B through mitosis
Q30479953The localization of inner centromeric protein (INCENP) at the cleavage furrow is dependent on Kif12 and involves interactions of the N terminus of INCENP with the actin cytoskeleton
Q41717680The phosphorylation of a kinetochore protein Dam1 by Aurora B/Ipl1 kinase promotes chromosome bipolar attachment in yeast
Q36333350The role of centromere-binding factor 3 (CBF3) in spindle stability, cytokinesis, and kinetochore attachment.
Q33976673The spindle checkpoint, aneuploidy, and cancer
Q33992545Unrestrained spindle elongation during recovery from spindle checkpoint activation in cdc15-2 cells results in mis-segregation of chromosomes
Q27022835Visualizing kinetochore architecture
Q27932728Ypi1, a positive regulator of nuclear protein phosphatase type 1 activity in Saccharomyces cerevisiae.

Search more.