Kinase signaling in the spindle checkpoint

scientific article published on 19 February 2009

Kinase signaling in the spindle checkpoint is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.R900005200
P932PMC publication ID2708832
P698PubMed publication ID19228686

P2093author name stringHongtao Yu
Jungseog Kang
P2860cites workPhosphorylation- and polo-box-dependent binding of Plk1 to Bub1 is required for the kinetochore localization of Plk1Q24292817
Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1Q24299555
The human spindle assembly checkpoint protein Bub3 is required for the establishment of efficient kinetochore-microtubule attachmentsQ24306626
Mps1 phosphorylates Borealin to control Aurora B activity and chromosome alignmentQ24310028
NEK2A interacts with MAD1 and possibly functions as a novel integrator of the spindle checkpoint signalingQ24310671
Polo-like kinase-1 is activated by aurora A to promote checkpoint recoveryQ24311665
Mapping the assembly pathways that specify formation of the trilaminar kinetochore plates in human cellsQ36118921
Cdk1 phosphorylation of BubR1 controls spindle checkpoint arrest and Plk1-mediated formation of the 3F3/2 epitopeQ36149262
Autophosphorylation-dependent activation of human Mps1 is required for the spindle checkpointQ36299859
Kinetochore-microtubule interactions: the means to the endQ36606737
Phosphorylation sites in BubR1 that regulate kinetochore attachment, tension, and mitotic exitQ36972632
Regulation of kinetochore recruitment of two essential mitotic spindle checkpoint proteins by Mps1 phosphorylationQ37035104
Polo on the Rise-from Mitotic Entry to Cytokinesis with Plk1.Q37162736
Phosphorylation and activation of Bub1 on unattached chromosomes facilitate the spindle checkpointQ37491603
BubR1 and APC/EB1 cooperate to maintain metaphase chromosome alignmentQ39746594
BubR1 N terminus acts as a soluble inhibitor of cyclin B degradation by APC/C(Cdc20) in interphaseQ42575503
Chromosomal enrichment and activation of the aurora B pathway are coupled to spatially regulate spindle assemblyQ42745909
A dual role for Bub1 in the spindle checkpoint and chromosome congressionQ42844867
Autophosphorylation of a newly identified site of Aurora-B is indispensable for cytokinesisQ44727121
Activating and silencing the mitotic checkpoint through CENP-E-dependent activation/inactivation of BubR1.Q45952803
Polo-like kinase 1 facilitates chromosome alignment during prometaphase through BubR1.Q51991100
Chk1 is required for spindle checkpoint function.Q52576772
GFP tagging reveals human Polo-like kinase 1 at the kinetochore/centromere region of mitotic chromosomesQ57277601
Mps1 phosphorylation by MAP kinase is required for kinetochore localization of spindle-checkpoint proteinsQ80206801
The human mitotic checkpoint protein BubR1 regulates chromosome-spindle attachmentsQ81126953
Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congressionQ24316498
The mitotic checkpoint kinase NEK2A regulates kinetochore microtubule attachment stabilityQ24317171
The conserved KMN network constitutes the core microtubule-binding site of the kinetochoreQ24320105
Human Bub1 protects centromeric sister-chromatid cohesion through Shugoshin during mitosisQ24558607
Linking kinetochore-microtubule binding to the spindle checkpointQ24646166
Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signalingQ24679267
Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosisQ24682520
Bub1 is essential for assembly of the functional inner centromere.Q24683337
Cell signaling by receptor tyrosine kinasesQ27860474
The spindle-assembly checkpoint in space and timeQ27860766
Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanismQ27930787
Functional cooperation of Dam1, Ipl1, and the inner centromere protein (INCENP)-related protein Sli15 during chromosome segregationQ27935335
Bora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entryQ28115829
Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2Q28204299
Regulation of APC-Cdc20 by the spindle checkpointQ28216974
Complex formation of Plk1 and INCENP required for metaphase-anaphase transitionQ28288825
Mad3 KEN boxes mediate both Cdc20 and Mad3 turnover, and are critical for the spindle checkpointQ28469167
Kinetochore microtubule dynamics and attachment stability are regulated by Hec1Q29618389
On the road to cancer: aneuploidy and the mitotic checkpointQ29619455
Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connectionsQ29619579
Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assemblyQ30440998
Activation of the MKK/ERK pathway during somatic cell mitosis: direct interactions of active ERK with kinetochores and regulation of the mitotic 3F3/2 phosphoantigen.Q30442086
Centromeric Aurora-B activation requires TD-60, microtubules, and substrate priming phosphorylationQ30445470
Kinetochore localization of spindle checkpoint proteins: who controls whom?Q30448761
Distinct sequence elements of cyclin B1 promote localization to chromatin, centrosomes, and kinetochores during mitosisQ30480758
The spindle checkpoint, aneuploidy, and cancerQ33976673
Functional studies on the role of the C-terminal domain of mammalian polo-like kinaseQ34011891
Mad2-Independent inhibition of APCCdc20 by the mitotic checkpoint protein BubR1.Q34101240
Regulation of mitotic chromosome cohesion by Haspin and Aurora B.Q34579183
Cdc20: a WD40 activator for a cell cycle degradation machineQ34646331
Mps1 activation loop autophosphorylation enhances kinase activity.Q34668543
Interfaces between the detection, signaling, and repair of DNA damageQ34762844
Mad3p, a pseudosubstrate inhibitor of APCCdc20 in the spindle assembly checkpointQ35677350
Tension-sensitive Plk1 phosphorylation on BubR1 regulates the stability of kinetochore microtubule interactionsQ35946386
P433issue23
P407language of work or nameEnglishQ1860
P1104number of pages5
P304page(s)15359-15363
P577publication date2009-02-19
P1433published inJournal of Biological ChemistryQ867727
P1476titleKinase signaling in the spindle checkpoint
P478volume284

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cites work (P2860)
Q42956392A novel protein phosphatase 1-dependent spindle checkpoint silencing mechanism
Q33709439An oral quinoline derivative, MPT0B392, causes leukemic cells mitotic arrest and overcomes drug resistant cancer cells
Q35869925Arabidopsis Cell Division Cycle 20.1 Is Required for Normal Meiotic Spindle Assembly and Chromosome Segregation.
Q42167079Constitutive Mad1 targeting to kinetochores uncouples checkpoint signalling from chromosome biorientation
Q34026669Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine
Q37783732Function of Protein Phosphatase-1, Glc7, in Saccharomyces cerevisiae
Q30500882KNL1/Spc105 recruits PP1 to silence the spindle assembly checkpoint
Q42116229Kinase activity of fission yeast Mph1 is required for Mad2 and Mad3 to stably bind the anaphase promoting complex
Q35925170Mps1Mph1 Kinase Phosphorylates Mad3 to Inhibit Cdc20Slp1-APC/C and Maintain Spindle Checkpoint Arrests
Q35011977Overexpression of the dynein light chain km23-1 in human ovarian carcinoma cells inhibits tumor formation in vivo and causes mitotic delay at prometaphase/metaphase
Q37317376Protein phosphatase 1 regulates exit from the spindle checkpoint in budding yeast
Q64058303Recent Progress on the Localization of the Spindle Assembly Checkpoint Machinery to Kinetochores
Q28087413Regulatory roles of phosphorylation in model and pathogenic fungi
Q92932427Role of protein phosphatases PP1, PP2A, PP4 and Cdc14 in the DNA damage response
Q46957547Role of the Y-located putative gonadoblastoma gene in human spermatogenesis
Q37956287Spindle assembly checkpoint: the third decade
Q37063126The composition, functions, and regulation of the budding yeast kinetochore
Q30540340UV-C irradiation delays mitotic progression by recruiting Mps1 to kinetochores
Q30504218Zwint-1 is a novel Aurora B substrate required for the assembly of a dynein-binding platform on kinetochores.