Galectin-3 and IL-33/ST2 axis roles and interplay in diet-induced steatohepatitis

scientific article

Galectin-3 and IL-33/ST2 axis roles and interplay in diet-induced steatohepatitis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3748/WJG.V22.I44.9706
P8608Fatcat IDrelease_uennxdc2pjbvdk2qdbzoiai5xa
P932PMC publication ID5124975
P698PubMed publication ID27956794

P50authorNada PejnovićQ64433631
Ilija JefticQ86719097
Nebojsa ArsenijevicQ47155565
Nemanja U JovicicQ61109629
P2093author name stringMiodrag L Lukic
P2860cites workAdvanced glycation end products are eliminated by scavenger-receptor-mediated endocytosis in hepatic sinusoidal Kupffer and endothelial cellsQ24530074
Galectin-3 regulates myofibroblast activation and hepatic fibrosisQ24546358
Non-alcoholic fatty liver disease: what the clinician needs to knowQ24563068
Insulin resistance in development and progression of nonalcoholic fatty liver diseaseQ26748687
Novel Molecular Mechanisms in the Development of Non-Alcoholic SteatohepatitisQ26766533
Role of Galectin-3 in Obesity and Impaired Glucose HomeostasisQ26771826
The role of fatty acids in insulin resistanceQ26785440
Lessons from mouse models of high-fat diet-induced NAFLDQ26829532
Role of cytokines and chemokines in non-alcoholic fatty liver diseaseQ26830328
The roles of Galectin-3 in autoimmunity and tumor progressionQ28261890
Regression of fibrosis and reversal of cirrhosis in rats by galectin inhibitors in thioacetamide-induced liver diseaseQ28534290
IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling systemQ28585033
IL-33 reduces the development of atherosclerosisQ28594104
Steatohepatitis: a tale of two "hits"?Q29547771
Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesisQ29619888
Evolving concepts in the pathogenesis of NASH: beyond steatosis and inflammationQ33755829
Reduction of galectin-3 expression and liver fibrosis after cell therapy in a mouse model of cirrhosisQ34093510
Endogenous lectins from cultured cells: nuclear localization of carbohydrate-binding protein 35 in proliferating 3T3 fibroblastsQ34345937
Cytokine receptors and signaling in hepatic stellate cellsQ34391388
Galectin-3: an open-ended storyQ34494555
Increased adiposity, dysregulated glucose metabolism and systemic inflammation in Galectin-3 KO miceQ34603941
Interleukin-33 induces protective effects in adipose tissue inflammation during obesity in miceQ34626217
Inflammatory links between obesity and metabolic diseaseQ35015802
Role of galectin-3 in diabetic nephropathyQ35182376
IL-1 signaling in obesity-induced hepatic lipogenesis and steatosisQ35250416
Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation.Q35574021
Differential Immunometabolic Phenotype in Th1 and Th2 Dominant Mouse Strains in Response to High-Fat FeedingQ35720450
Mechanisms Linking Inflammation to Insulin ResistanceQ35744922
Inflammation as a Link between Obesity and Metabolic SyndromeQ35864675
Galectin-3 Ablation Enhances Liver Steatosis, but Attenuates Inflammation and IL-33-Dependent Fibrosis in Obesogenic Mouse Model of Nonalcoholic SteatohepatitisQ36025690
On the role of galectin-3 in cancer apoptosisQ36103556
When galectins recognize glycans: from biochemistry to physiology and back againQ36196146
Interleukin-33 is hepatoprotective during liver ischemia/reperfusion in miceQ36301170
Galectin-3 deficiency prevents concanavalin A-induced hepatitis in miceQ61903452
Protective role of IL-33/ST2 axis in Con A-induced hepatitisQ61903472
The role of galectin-3 in endocytosis of advanced glycation end products and modified low density lipoproteinsQ73405607
Liver fibrosisQ80851925
Galectin-3, a marker of cardiac fibrosis, predicts incident heart failure in the communityQ36439679
Role of galectin-3 in classical and alternative macrophage activation in the liver following acetaminophen intoxicationQ36456913
Detection of galectin-3 interaction with commensal bacteria.Q36827014
Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors.Q36887564
Phosphorylation of IRS proteins, insulin action, and insulin resistanceQ37252616
Interleukin-33 overexpression is associated with liver fibrosis in mice and humans.Q37311036
Can Serum ST2 Levels Be Used as a Marker of Fibrosis in Chronic Hepatitis B Infection?Q37328464
IL-33 treatment attenuated diet-induced hepatic steatosis but aggravated hepatic fibrosisQ37376114
Hepatic inflammation and progressive liver fibrosis in chronic liver diseaseQ37629675
Mechanisms of hepatic fibrogenesisQ37865859
Defining macrophage phenotype and function in adipose tissueQ37880478
IL-33/ST2 axis in inflammation and immunopathology.Q37990785
The cellular and signaling networks linking the immune system and metabolism in diseaseQ37991199
Soluble ST2 and galectin-3 in heart failureQ38186257
Functions of galectin-3 and its role in fibrotic diseasesQ38246458
Galectin-3: an emerging all-out player in metabolic disorders and their complicationsQ38258947
Galectin-3 stimulates cell proliferationQ38330513
ST2 testing for chronic heart failure therapy monitoring: the International ST2 Consensus PanelQ38351562
Interleukin 33 is a guardian of barriers and a local alarminQ38702558
Galectin-3-induced cell spreading and motility relies on distinct signaling mechanisms compared to fibronectinQ38774367
Regulation of alternative macrophage activation by galectin-3.Q40016366
Metabolically Healthy Obesity and the Development of Nonalcoholic Fatty Liver DiseaseQ40751811
High Serum Levels of the Interleukin-33 Receptor Soluble ST2 as a Negative Prognostic Factor in Hepatocellular CarcinomaQ40917751
Galectin-3 deficiency accelerates high-fat diet-induced obesity and amplifies inflammation in adipose tissue and pancreatic isletsQ40944709
IL-33 Reverses an Obesity-Induced Deficit in Visceral Adipose Tissue ST2+ T Regulatory Cells and Ameliorates Adipose Tissue Inflammation and Insulin Resistance.Q41077951
Functional evidence that cell surface galectin-3 mediates homotypic cell adhesion.Q41322039
Interleukin-33-dependent innate lymphoid cells mediate hepatic fibrosisQ41945735
Galectin-3 is a regulator of metaflammation in adipose tissue and pancreatic isletsQ42624178
Animal models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitisQ43174499
Do advanced glycation end products contribute to the development of long-term diabetic complications?Q43458994
Head-to-head comparison of 2 myocardial fibrosis biomarkers for long-term heart failure risk stratification: ST2 versus galectin-3.Q44118879
Serum levels of the interleukin-1 receptor family member ST2 predict mortality and clinical outcome in acute myocardial infarctionQ44245130
Galectin-3 is an independent marker for ventricular remodeling and mortality in patients with chronic heart failureQ44426645
Galectin-3 ablation protects mice from diet-induced NASH: a major scavenging role for galectin-3 in liver.Q45052723
Galectin-3 is a negative regulator of lipopolysaccharide-mediated inflammationQ46442221
Accelerated lipid-induced atherogenesis in galectin-3-deficient mice: role of lipoxidation via receptor-mediated mechanisms.Q48024001
Disrupted galectin-3 causes non-alcoholic fatty liver disease in male mice.Q52574179
Deficiency in galectin-3 promotes hepatic injury in CDAA diet-induced nonalcoholic fatty liver disease.Q55692292
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P433issue44
P407language of work or nameEnglishQ1860
P921main subjecthuman digestive systemQ9649
peptideQ172847
Galectin 3Q3094567
lectinQ408693
membrane proteinQ423042
metabolic dysfunction–associated steatotic liver diseaseQ1546498
steatohepatitisQ2335423
cell surface receptorQ2476074
physiological phenomenonQ66615932
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)9706-9717
P577publication date2016-11-01
P1433published inWorld Journal of GastroenterologyQ15708885
P1476titleGalectin-3 and IL-33/ST2 axis roles and interplay in diet-induced steatohepatitis
P478volume22

Reverse relations

cites work (P2860)
Q94465802An Integrated Approach Exploring the Synergistic Mechanism of Herbal Pairs in a Botanical Dietary Supplement: A Case Study of a Liver Protection Health Food
Q98178483An Overview of Lipid Metabolism and Nonalcoholic Fatty Liver Disease
Q90073141Galectin-3 as a Next-Generation Biomarker for Detecting Early Stage of Various Diseases
Q47127784IL-33-ST2 Axis in Liver Disease: Progression and Challenge
Q55514878IL-33/ST2 Pathway and Galectin-3 as a New Analytes in Pathogenesis and Cardiometabolic Risk Evaluation in Psychosis.
Q53137711Inflammation and insulin resistance: New targets encourage new thinking: Galectin-3 and LTB4 are pro-inflammatory molecules that can be targeted to restore insulin sensitivity.
Q55308149Mice lacking galectin-3 (Lgals3) function have decreased home cage movement.
Q58745474NLRP3 Inflammasome and IL-33: Novel Players in Sterile Liver Inflammation
Q92162938Redefining Cirrhotic Cardiomyopathy for the Modern Era
Q89891175The pro-inflammatory marker soluble suppression of tumorigenicity-2 (ST2) is reduced especially in diabetic morbidly obese patients undergoing bariatric surgery
Q55353688Usefulness of Enhanced Liver Fibrosis, Glycosylation Isomer of Mac-2 Binding Protein, Galectin-3, and Soluble Suppression of Tumorigenicity 2 for Assessing Liver Fibrosis in Chronic Liver Diseases.

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