Tertiary Lymphoid Organs in Central Nervous System Autoimmunity

scientific article

Tertiary Lymphoid Organs in Central Nervous System Autoimmunity is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3389/FIMMU.2016.00451
P8608Fatcat IDrelease_gbg23clevffltj5spso5vfmvte
P3181OpenCitations bibliographic resource ID2806431
P932PMC publication ID5078318
P698PubMed publication ID27826298

P2093author name stringMeike Mitsdoerffer
Anneli Peters
P2860cites workIL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 productionQ24338636
Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22Q24648620
Cytokine-Defined B Cell Responses as Therapeutic Targets in Multiple SclerosisQ26771459
The Ins and Outs of B Cells in Multiple SclerosisQ26776542
Ectopic lymphoid follicles: inducible centres for generating antigen-specific immune responses within tissuesQ26778348
A role for Th17 cells in the regulation of tertiary lymphoid folliclesQ26851559
A dural lymphatic vascular system that drains brain interstitial fluid and macromoleculesQ27308814
Structural and functional features of central nervous system lymphatic vesselsQ27316769
B-cell depletion with rituximab in relapsing-remitting multiple sclerosisQ28268626
Revisiting the Mechanisms of CNS Immune PrivilegeQ30278584
Artery Tertiary Lymphoid Organs Control Aorta Immunity and Protect against Atherosclerosis via Vascular Smooth Muscle Cell Lymphotoxin β ReceptorsQ30279169
Localizing central nervous system immune surveillance: meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitisQ30510541
2-photon imaging of phagocyte-mediated T cell activation in the CNS.Q30536629
Revised diagnostic criteria of multiple sclerosisQ30733519
Gray matter damage in multiple sclerosis: Impact on clinical symptomsQ30979785
Lymphotoxin beta receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE-/- miceQ33399367
Cortical lesions in multiple sclerosisQ33631075
Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosisQ33862720
Changes in B- and T-lymphocyte and chemokine levels with rituximab treatment in multiple sclerosis.Q34052870
Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypesQ34066077
Proinflammatory T helper type 17 cells are effective B-cell helpersQ34069686
B cells regulate autoimmunity by provision of IL-10.Q34150590
The development of inducible bronchus-associated lymphoid tissue depends on IL-17.Q34191942
Immunoglobulin class-switched B cells form an active immune axis between CNS and periphery in multiple sclerosis.Q34251673
Meningeal inflammation plays a role in the pathology of primary progressive multiple sclerosisQ34295012
Real-time in vivo analysis of T cell activation in the central nervous system using a genetically encoded calcium indicatorQ34345420
Extensive grey matter pathology in the cerebellum in multiple sclerosis is linked to inflammation in the subarachnoid spaceQ34449329
Related B cell clones populate the meninges and parenchyma of patients with multiple sclerosisQ34538912
Related B cell clones that populate the CSF and CNS of patients with multiple sclerosis produce CSF immunoglobulinQ34960518
Spontaneous opticospinal encephalomyelitis in a double-transgenic mouse model of autoimmune T cell/B cell cooperation.Q35009513
Myelin oligodendrocyte glycoprotein-specific T and B cells cooperate to induce a Devic-like disease in miceQ35009518
Effector and regulatory T-cell subsets in autoimmunity and tissue inflammationQ35084618
B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodesQ35298764
Inflammatory cortical demyelination in early multiple sclerosisQ35764685
IL-22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organsQ36055624
Central Nervous System and Peripheral Expression of CCL19, CCL21 and Their Receptor CCR7 in Experimental Model of Multiple SclerosisQ36065424
RORγt Expression and Lymphoid Neogenesis in the Brain of Patients with Secondary Progressive Multiple SclerosisQ36076923
Meningeal Infiltration of the Spinal Cord by Non-Classically Activated B Cells is Associated with Chronic Disease Course in a Spontaneous B Cell-Dependent Model of CNS Autoimmune DiseaseQ36097332
CXCL13 is the major determinant for B cell recruitment to the CSF during neuroinflammationQ36161486
Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammationQ36174679
Integration of Th17- and Lymphotoxin-Derived Signals Initiates Meningeal-Resident Stromal Cell Remodeling to Propagate Neuroinflammation.Q49130159
Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis.Q51027456
The rapid isolation of clonable antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitisQ53438445
Lineage Relationship Analysis of RORγt+Innate Lymphoid CellsQ57520258
Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesionsQ59070288
Multiple sclerosis: BAFF and CXCL13 in cerebrospinal fluidQ59543689
CCL19 is constitutively expressed in the CNS, up-regulated in neuroinflammation, active and also inactive multiple sclerosis lesionsQ60197446
Suppression of established experimental autoimmune encephalomyelitis and formation of meningeal lymphoid follicles by lymphotoxin β receptor-Ig fusion proteinQ60455093
Immunopathology of multiple sclerosisQ63285399
Cytokines and adhesion molecules contribute to the ability of myelin proteolipid protein-specific T cell clones to mediate experimental allergic encephalomyelitisQ63535318
B cells are critical to induction of experimental allergic encephalomyelitis by protein but not by a short encephalitogenic peptideQ73170385
Critical role of antigen-specific antibody in experimental autoimmune encephalomyelitis induced by recombinant myelin oligodendrocyte glycoproteinQ74456215
The pathology of multiple sclerosis is location-dependent: no significant complement activation is detected in purely cortical lesionsQ81485093
Dysregulated Epstein-Barr virus infection in the multiple sclerosis brainQ36229219
Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchymaQ36361169
Myelin basic protein-specific T helper 2 (Th2) cells cause experimental autoimmune encephalomyelitis in immunodeficient hosts rather than protect them from the diseaseQ36380402
Autopathogenic T helper cell type 1 (Th1) and protective Th2 clones differ in their recognition of the autoantigenic peptide of myelin proteolipid proteinQ36380584
Lymphoid organ development: from ontogeny to neogenesisQ36426808
Germinal-center organization and cellular dynamicsQ36459345
Mechanisms regulating regional localization of inflammation during CNS autoimmunity.Q36918129
Follicular dendritic cells emerge from ubiquitous perivascular precursorsQ36991851
Inhibition of LTi cell development by CD25 blockade is associated with decreased intrathecal inflammation in multiple sclerosisQ37354974
CXCL13 is a biomarker of inflammation in multiple sclerosis, neuromyelitis optica, and other neurological conditionsQ37646434
Stromal cell-immune cell interactionsQ37809072
Receptor-mediated antigen uptake and its effect on antigen presentation to class II-restricted T lymphocytesQ37925555
The clinical course of multiple sclerosisQ38186214
Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis.Q38196701
Th17 cells in central nervous system autoimmunityQ38200386
Ectopic lymphoid-like structures in infection, cancer and autoimmunityQ38221815
The biology of innate lymphoid cellsQ38319907
Role of the innate and adaptive immune responses in the course of multiple sclerosisQ38384621
Molecular biomarkers in cerebrospinal fluid of multiple sclerosis patients.Q38526863
IL-17-induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCsQ38641655
Increased prevalence of lymphoid tissue inducer cells in the cerebrospinal fluid of patients with early multiple sclerosisQ38954794
Central nervous system infiltrates are characterized by features of ongoing B cell-related immune activity in MP4-induced experimental autoimmune encephalomyelitisQ41184150
Multiple sclerosis: presence of lymphatic capillaries and lymphoid tissue in the brain and spinal cordQ41466361
Phenotypical and functional characterization of T helper 17 cells in multiple sclerosisQ42463447
A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis.Q42847184
Tertiary lymphoid organ development coincides with determinant spreading of the myelin-specific T cell responseQ43887998
Rat and human myelin oligodendrocyte glycoproteins induce experimental autoimmune encephalomyelitis by different mechanisms in C57BL/6 miceQ44484576
Identification of autoantibodies associated with myelin damage in multiple sclerosisQ46424597
IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentiumQ46485022
Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis.Q47357498
Intracortical multiple sclerosis lesions are not associated with increased lymphocyte infiltrationQ47680006
Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology.Q48200750
Lack of correlation between cortical demyelination and white matter pathologic changes in multiple sclerosisQ48315824
CXCL12 limits inflammation by localizing mononuclear infiltrates to the perivascular space during experimental autoimmune encephalomyelitisQ48365016
Meningeal inflammation is not associated with cortical demyelination in chronic multiple sclerosisQ48485900
Multiple sclerosis: in situ evidence for antibody- and complement-mediated demyelinationQ48489118
Functional expression of the lymphoid chemokines CCL19 (ELC) and CCL 21 (SLC) at the blood-brain barrier suggests their involvement in G-protein-dependent lymphocyte recruitment into the central nervous system during experimental autoimmune encephalQ48494770
A new focal EAE model of cortical demyelination: multiple sclerosis-like lesions with rapid resolution of inflammation and extensive remyelinationQ48530177
Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitmentQ48701331
The association of intrathecal immunoglobulin synthesis and cortical lesions predicts disease activity in clinically isolated syndrome and early relapsing-remitting multiple sclerosisQ48932530
Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosisQ48949792
P407language of work or nameEnglishQ1860
P921main subjecttertiary lymphoid organQ108017266
P304page(s)451
P577publication date2016-10-25
P1433published inFrontiers in ImmunologyQ27723748
P1476titleTertiary Lymphoid Organs in Central Nervous System Autoimmunity
P478volume7

Reverse relations

cites work (P2860)
Q92538007Anti-Myelin Proteolipid Protein Peptide Monoclonal Antibodies Recognize Cell Surface Proteins on Developing Neurons and Inhibit Their Differentiation
Q64996917Contribution of LTi and TH17 cells to B cell aggregate formation in the central nervous system in a mouse model of multiple sclerosis.
Q57175799Induction of Tertiary Lymphoid Structures With Antitumor Function by a Lymph Node-Derived Stromal Cell Line
Q63363253Innate, innate-like and adaptive lymphocytes in the pathogenesis of MS and EAE
Q89495110Lymphoid Aggregates in the CNS of Progressive Multiple Sclerosis Patients Lack Regulatory T Cells
Q49795149Lymphotoxin β receptor-mediated NFκB signaling promotes glial lineage differentiation and inhibits neuronal lineage differentiation in mouse brain neural stem/progenitor cells
Q64118459Mechanisms of neurobehavioral abnormalities in multiple sclerosis: Contributions from neural and immune components
Q57825775Role of CXCL13 in the formation of the meningeal tertiary lymphoid organ in multiple sclerosis
Q89278062Role of chemokines in ectopic lymphoid structures formation in autoimmunity and cancer
Q41000187Serum Lymphocyte-Associated Cytokine Concentrations Change More Rapidly over Time in Multiple System Atrophy Compared to Parkinson Disease.
Q64242492Severe headache in primary Sjögren's syndrome treated with intrathecal rituximab
Q39110320T cell responses in the central nervous system
Q90578057T lymphocytes and cytotoxic astrocyte blebs correlate across autism brains
Q58746430Tertiary Lymphoid Structures: Autoimmunity Goes Local
Q39201665Tertiary lymphoid organs in systemic autoimmune diseases:  pathogenic or protective?
Q41848000Use of Toll-Like Receptor Agonists to Induce Ectopic Lymphoid Structures in Myasthenia Gravis Mouse Models.

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