Regulation of Nlrp3 inflammasome by dietary metabolites

scientific article

Regulation of Nlrp3 inflammasome by dietary metabolites is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.SMIM.2015.10.004
P932PMC publication ID4821737
P698PubMed publication ID26776831

P2093author name stringChristina Camell
Emily Goldberg
Vishwa Deep Dixit
P2860cites workOmega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation.Q50870985
Myeloid-related proteins 8 and 14 contribute to monosodium urate monohydrate crystal-induced inflammation in gout.Q54225782
The NLRP3/ASC/Caspase-1 axis regulates IL-1β processing in neutrophils.Q54331250
NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B4 in a murine model of goutQ56797722
Effects of n-6 PUFAs compared with SFAs on liver fat, lipoproteins, and inflammation in abdominal obesity: a randomized controlled trialQ60057004
The β-hydroxybutyrate receptor HCA2 activates a neuroprotective subset of macrophagesQ60687194
A high-fat meal induces low-grade endotoxemia: evidence of a novel mechanism of postprandial inflammationQ60998567
Ceramide kinase deficiency improves diet-induced obesity and insulin resistanceQ83783188
Prevalence of gout and hyperuricemia in the US general population: the National Health and Nutrition Examination Survey 2007-2008Q84617958
A pilot study of IL-1 inhibition by anakinra in acute goutQ21195421
An overview of sphingolipid metabolism: from synthesis to breakdownQ24628769
Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasisQ24629044
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilizationQ24631966
CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimerQ24642646
IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiationQ24649009
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silicaQ24649598
Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammationQ24682128
The adipokine/ceramide axis: key aspects of insulin sensitizationQ27025041
Gout-associated uric acid crystals activate the NALP3 inflammasomeQ28131797
Mammalian lipoxygenases and their biological relevanceQ28249730
Medium-chain fatty acids as ligands for orphan G protein-coupled receptor GPR84Q28263047
Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetesQ28264518
Cryopyrin activates the inflammasome in response to toxins and ATPQ28291313
Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistanceQ28291556
CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammationQ28506984
Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120Q28507400
Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43Q28509150
Thioredoxin-interacting protein links oxidative stress to inflammasome activationQ29614471
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystalsQ29615704
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signalingQ29616024
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistanceQ29616026
Type 2 diabetes as an inflammatory diseaseQ29617184
CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesityQ29617380
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parametersQ29617381
Interleukin-1-receptor antagonist in type 2 diabetes mellitusQ29619001
K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matterQ29620146
Myeloid cell-specific serine palmitoyltransferase subunit 2 haploinsufficiency reduces murine atherosclerosisQ30538274
Succinate is an inflammatory signal that induces IL-1β through HIF-1α.Q33652731
Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome.Q33982897
Lipid storage by adipose tissue macrophages regulates systemic glucose toleranceQ34062793
Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophagesQ34071063
Weight loss and lipolysis promote a dynamic immune response in murine adipose tissueQ34162171
Calorie restriction and prevention of age-associated chronic disease.Q34170610
Identification of an adipogenic niche for adipose tissue remodeling and restorationQ34289690
Metabolic dysfunction drives a mechanistically distinct proinflammatory phenotype in adipose tissue macrophagesQ34316035
Macrophages in atherosclerosis: a dynamic balance.Q34368005
CCR2 deficiency leads to increased eosinophils, alternative macrophage activation, and type 2 cytokine expression in adipose tissue.Q34474720
Targeted Induction of Ceramide Degradation Leads to Improved Systemic Metabolism and Reduced Hepatic SteatosisQ34485836
Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instabilityQ34601356
Transcriptome-based network analysis reveals a spectrum model of human macrophage activation.Q34659689
Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria.Q34678595
Hematopoietic cell-restricted deletion of CD36 reduces high-fat diet-induced macrophage infiltration and improves insulin signaling in adipose tissueQ34718662
The monocarboxylate transporter 4 is required for glycolytic reprogramming and inflammatory response in macrophages.Q34801576
The impact of polyunsaturated fatty acid-based dietary supplements on disease biomarkers in a metabolic syndrome/diabetes populationQ34915433
Dietary oleic acid increases m2 macrophages in the mesenteric adipose tissueQ35009952
UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsisQ35056779
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory diseaseQ35155012
Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ effluxQ35206149
Inflammasome is a central player in the induction of obesity and insulin resistanceQ35216914
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.Q35350543
Elimination of the NLRP3-ASC inflammasome protects against chronic obesity-induced pancreatic damageQ35417136
Regulation of inflammasome activationQ35456425
Visualized macrophage dynamics and significance of S100A8 in obese fatQ35549380
Pathways and control of ketone body metabolism: on the fringe of lipid biochemistryQ35652442
A 2-Year Randomized Controlled Trial of Human Caloric Restriction: Feasibility and Effects on Predictors of Health Span and LongevityQ35695494
Increased macrophage migration into adipose tissue in obese miceQ35696560
Interleukin-1 (IL-1) signaling in intestinal stromal cells controls KC/ CXCL1 secretion, which correlates with recruitment of IL-22- secreting neutrophils at early stages of Citrobacter rodentium infectionQ35833796
Akt3 deficiency in macrophages promotes foam cell formation and atherosclerosis in miceQ36024453
Short term high fat diet challenge promotes alternative macrophage polarization in adipose tissue via natural killer T cells and interleukin-4.Q36097975
Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient miceQ36375776
Antigen- and cytokine-driven accumulation of regulatory T cells in visceral adipose tissue of lean miceQ36561831
Palmitate and lipopolysaccharide trigger synergistic ceramide production in primary macrophagesQ36579422
Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophagesQ36694157
Macrophage lipoprotein lipase modulates the development of atherosclerosis but not adiposityQ36709603
Cellular cholesterol trafficking and compartmentalizationQ37064008
Unsaturated fatty acids prevent activation of NLRP3 inflammasome in human monocytes/macrophagesQ37222666
Glyburide inhibits the Cryopyrin/Nalp3 inflammasomeQ37387873
Sphingosine kinase 1 regulates adipose proinflammatory responses and insulin resistanceQ37656009
The IL-1 family: regulators of immunityQ37676929
Old and new generation lipid mediators in acute inflammation and resolutionQ37775277
Alternative macrophage activation and metabolismQ37804862
The monocarboxylate transporter family--role and regulationQ37967617
Neutrophils, IL-1β, and gout: is there a link?Q38076334
Mechanisms of NOD-like receptor-associated inflammasome activationQ38140207
Metabolic regulation of immune responsesQ38198155
Acyl-CoA metabolism and partitioningQ38211152
Mechanisms and functions of inflammasomesQ38214128
Protection from high fat diet-induced increase in ceramide in mice lacking plasminogen activator inhibitor 1.Q38291637
IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balanceQ38983262
Inhibition of macrophage fatty acid β-oxidation exacerbates palmitate-induced inflammatory and endoplasmic reticulum stress responsesQ39027982
DGAT1-dependent triacylglycerol storage by macrophages protects mice from diet-induced insulin resistance and inflammation.Q39250720
Pyruvate dehydrogenase kinase 1 participates in macrophage polarization via regulating glucose metabolismQ40949635
Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumptionQ41119321
Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation.Q41464597
T-cell recruitment and Th1 polarization in adipose tissue during diet-induced obesity in C57BL/6 miceQ41560139
Local proliferation of macrophages contributes to obesity-associated adipose tissue inflammationQ41838863
Interleukin-1beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expressionQ41862754
PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cellsQ42183814
Rates of utilization and fates of glucose, glutamine, pyruvate, fatty acids and ketone bodies by mouse macrophagesQ42523070
A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions.Q44081169
Comorbidities of gout and hyperuricemia in the US general population: NHANES 2007-2008.Q46075227
Interleukin-1 plays a major role in vascular inflammation and atherosclerosis in male apolipoprotein E-knockout miceQ46507912
Obesity, fat distribution, and weight gain as risk factors for clinical diabetes in men.Q47369917
Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intoleranceQ47431942
Lack of interleukin-1 receptor antagonist modulates plaque composition in apolipoprotein E-deficient miceQ47835280
IL-1 regulates in vivo C-X-C chemokine induction and neutrophil sequestration following endotoxemia.Q50109905
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectinflammasome complexQ412405
P304page(s)334-42
P577publication date2015-09-01
P1433published inSeminars in ImmunologyQ15762658
P1476titleRegulation of Nlrp3 inflammasome by dietary metabolites
P478volume27

Reverse relations

cites work (P2860)
Q99561717Gut microbiota, NLR proteins, and intestinal homeostasis
Q39236078How Factors Involved in the Resolution of Crystal-Induced Inflammation Target IL-1β.
Q49501276Immunometabolism in 2017: Metabolism and the inflammasome in health and ageing.
Q39331486Role of dietary fatty acids in liver injury caused by vinyl chloride metabolites in mice.
Q39036066The role of caloric load and mitochondrial homeostasis in the regulation of the NLRP3 inflammasome
Q60924142The role of hepatic macrophages in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

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