Aldehyde dehydrogenase 2 in aplastic anemia, Fanconi anemia and hematopoietic stem cells

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Aldehyde dehydrogenase 2 in aplastic anemia, Fanconi anemia and hematopoietic stem cells is …
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review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.YMGME.2016.07.004
P8608Fatcat IDrelease_toj7zjmhl5a43l2apuvczyngce
P932PMC publication ID5082284
P698PubMed publication ID27650066

P50authorDaria Mochly-RosenQ56073232
P2093author name stringKenneth I. Weinberg
Lauren D. Van Wassenhove
P2860cites workAplastic anemiaQ81025689
Aldehyde dehydrogenase-2 polymorphism contributes to the progression of bone marrow failure in children with idiopathic aplastic anaemiaQ85289952
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Refined geographic distribution of the oriental ALDH2*504Lys (nee 487Lys) variantQ24611914
Genotypes for aldehyde dehydrogenase deficiency and alcohol sensitivity. The inactive ALDH2(2) allele is dominantQ24628653
Acetaldehyde stimulates FANCD2 monoubiquitination, H2AX phosphorylation, and BRCA1 phosphorylation in human cells in vitro: implications for alcohol-related carcinogenesisQ24645589
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Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heartQ24656840
Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cellsQ24676524
Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variantQ27658903
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Catalytic contribution of threonine 244 in human ALDH2Q28282806
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Activation of aldehyde dehydrogenase 2 (ALDH2) confers cardioprotection in protein kinase C epsilon (PKCvarepsilon) knockout miceQ33724453
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Aldehyde dehydrogenase 2 in cardiac protection: a new therapeutic target?Q33797190
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Aldehyde dehydrogenase activation prevents reperfusion arrhythmias by inhibiting local renin release from cardiac mast cellsQ39669262
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In vitro effect of fludarabine, cyclophosphamide, and cytosine arabinoside on chromosome breakage in Fanconi anemia patients: relevance to stem cell transplantationQ80273731
Aldehyde dehydrogenase 2 activation in heart failure restores mitochondrial function and improves ventricular function and remodelling.Q34137983
Fancd2 counteracts the toxic effects of naturally produced aldehydes in miceQ34198217
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Maternal aldehyde elimination during pregnancy preserves the fetal genomeQ34244123
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Aldehyde dehydrogenase-2 regulates nociception in rodent models of acute inflammatory painQ34522391
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Crosstalk between translesion synthesis, Fanconi anemia network, and homologous recombination repair pathways in interstrand DNA crosslink repair and development of chemoresistanceQ35205030
Aldehydic load and aldehyde dehydrogenase 2 profile during the progression of post-myocardial infarction cardiomyopathy: benefits of Alda-1Q35510238
Alcohol metabolism in human cells causes DNA damage and activates the Fanconi anemia-breast cancer susceptibility (FA-BRCA) DNA damage response networkQ35566416
A personalized medicine approach for Asian Americans with the aldehyde dehydrogenase 2*2 variantQ35619842
Is nonalcoholic fatty liver disease an endogenous alcoholic fatty liver disease? - A mechanistic hypothesisQ35625744
Correcting Neuromuscular Deficits With Gene Therapy in Pompe DiseaseQ35903220
Deficient CD4+ CD25+ FOXP3+ T regulatory cells in acquired aplastic anemia.Q35989456
Alcohol, ALDH2, and esophageal cancer: a meta-analysis which illustrates the potentials and limitations of a Mendelian randomization approachQ36231579
Aldehyde sources, metabolism, molecular toxicity mechanisms, and possible effects on human healthQ36370381
Natural history and management of Fanconi anemia patients with head and neck cancer: A 10-year follow-upQ36717334
Anemia of Central OriginQ36784115
Analysis of crotonaldehyde- and acetaldehyde-derived 1,n(2)-propanodeoxyguanosine adducts in DNA from human tissues using liquid chromatography electrospray ionization tandem mass spectrometry.Q36999501
Lessons learned about human stem cell responses to ionizing radiation exposures: a long road still ahead of us.Q37139081
Regulation of human hematopoietic stem cell self-renewal by the microenvironment's control of retinoic acid signalingQ37218410
Inhibition of aldehyde dehydrogenase expands hematopoietic stem cells with radioprotective capacityQ37539087
Acetaldehyde and the genome: beyond nuclear DNA adducts and carcinogenesisQ38166683
Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients.Q38267184
Aldehyde-modified proteins as mediators of early inflammation in atherosclerotic disease.Q38598292
Progress toward improved therapies for inborn errors of metabolismQ38601073
P433issue1-2
P407language of work or nameEnglishQ1860
P921main subjectFanconi anemiaQ845779
aplastic anemiaQ846316
P304page(s)28-36
P577publication date2016-09-01
P1433published inMolecular Genetics and MetabolismQ6895949
P1476titleAldehyde dehydrogenase 2 in aplastic anemia, Fanconi anemia and hematopoietic stem cells
P478volume119