| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1007/BF02215949 |
| P698 | PubMed publication ID | 7948302 |
| P2093 | author name string | I Pastan | |
| F Herrmann | |||
| T Licht | |||
| M Gottesman | |||
| P2860 | cites work | Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease | Q24322810 |
| Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues | Q24633406 | ||
| ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells | Q24650215 | ||
| The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein | Q27939661 | ||
| Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins | Q28116625 | ||
| Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein | Q28186115 | ||
| Separation of drug transport and chloride channel functions of the human multidrug resistance P-glycoprotein | Q28188274 | ||
| Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport | Q28257874 | ||
| Expression of the proliferation-associated Ki-67 antigen of transferrin receptors and of DNA polymerase? in human tumour lines: implications for in vitro chemoresistance | Q67744132 | ||
| Immunohistochemical identification of P-glycoprotein in previously untreated, diffuse large cell and immunoblastic lymphomas | Q67883182 | ||
| Clinical significance of multidrug resistance P-glycoprotein expression on acute nonlymphoblastic leukemia cells at diagnosis | Q67894802 | ||
| Analysis of multidrug resistance (MDR-1) gene expression in chronic lymphocytic leukaemia (CLL) | Q68000093 | ||
| High-level expression of P-glycoprotein and 85 kD protein as assessed by flow cytometry and immunocytochemistry in leukemias and malignant lymphomas | Q68172782 | ||
| P-glycoprotein expression in malignant lymphoma and reversal of clinical drug resistance with chemotherapy plus high-dose verapamil | Q68289591 | ||
| Magnetic-Affinity Cell Sorting of Human Multidrug-Resistant Cells | Q68294418 | ||
| Multidrug-resistant myeloma: laboratory and clinical effects of verapamil as a chemosensitizer | Q68307412 | ||
| Multidrug-resistance phenotype of a subpopulation of T-lymphocytes without drug selection | Q69120390 | ||
| Expression of a multidrug resistance gene in human cancers | Q69366790 | ||
| Immunohistochemical detection and quantitation of P-glycoprotein in multiple drug-resistant human myeloma cells: association with level of drug resistance and drug accumulation | Q69367572 | ||
| Active outward transport of daunomycin in resistant Ehrlich ascites tumor cells | Q69700007 | ||
| Tissue distribution of P-glycoprotein encoded by a multidrug-resistant gene as revealed by a monoclonal antibody, MRK 16 | Q69914948 | ||
| Pseudomonas exotoxin conjugated to monoclonal antibody MRK16 specifically kills multidrug resistant cells in cultured renal carcinomas and in MDR-transgenic mice | Q70522257 | ||
| Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil | Q70721995 | ||
| Expression of multidrug resistance P-glycoprotein on peripheral blood mononuclear cells of patients with granular lymphocyte-proliferative disorders | Q72071954 | ||
| Predominance of functional multidrug resistance (MDR-1) phenotype in CD34+ acute myeloid leukemia cells | Q72101168 | ||
| Expression of MDR1 gene in acute leukemia cells: association with CD7+ acute myeloblastic leukemia/acute lymphoblastic leukemia | Q72105970 | ||
| Cleavage of human MDR1 mRNA by a hammerhead ribozyme | Q72213537 | ||
| Phase I/II trial of cyclosporine as a chemotherapy-resistance modifier in acute leukemia | Q72229025 | ||
| Activity of P-glycoprotein in B-cell chronic lymphocytic leukemia determined by a flow cytometric assay | Q72234865 | ||
| Common expression of the multidrug resistance marker P-glycoprotein in B-cell chronic lymphocytic leukaemia and correlation with in vitro drug resistance | Q72656825 | ||
| The transporters associated with antigen presentation | Q28267198 | ||
| Structure of the human MDR3 gene and physical mapping of the human MDR locus | Q28268133 | ||
| Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells | Q28275578 | ||
| Glutathione metabolism and its selective modification | Q28289187 | ||
| Heat shock and arsenite increase expression of the multidrug resistance (MDR1) gene in human renal carcinoma cells | Q28334120 | ||
| Biochemistry of multidrug resistance mediated by the multidrug transporter | Q29616476 | ||
| In vitro response of human small-cell lung-cancer cell lines to chemotherapeutic drugs; no correlation with clinical data | Q30829744 | ||
| Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities | Q33495468 | ||
| A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells | Q33582717 | ||
| Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody | Q33611565 | ||
| Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction | Q33796247 | ||
| Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites | Q33832954 | ||
| Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR) | Q33970197 | ||
| Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein | Q34040187 | ||
| Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs | Q34059522 | ||
| Phase I trial of etoposide with cyclosporine as a modulator of multidrug resistance | Q34161308 | ||
| Mammalian multidrug-resistance gene: correlation of exon organization with structural domains and duplication of an ancestral gene | Q34299638 | ||
| A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants | Q34488592 | ||
| Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells. | Q34559072 | ||
| Expression of a multidrug-resistance gene in human tumors and tissues | Q34586576 | ||
| A monoclonal antibody-Pseudomonas toxin conjugate that specifically kills multidrug-resistant cells | Q34632908 | ||
| Cytotoxic and cytostatic effects of antitumor agents induced at the plasma membrane level | Q35183238 | ||
| Mechanisms of multidrug resistance in cancer treatment | Q35259390 | ||
| Genetic aspects of multidrug resistance | Q35264223 | ||
| P-glycoprotein-mediated multidrug resistance and cytotoxic effector cells | Q35268937 | ||
| Glutathione transferases and cancer | Q35815703 | ||
| Regulation of initial vinblastine influx by P-glycoprotein | Q35975817 | ||
| P-glycoprotein expression in normal and reactive bone marrows | Q35976039 | ||
| P-glycoprotein expression in primary breast cancer detected by immunocytochemistry with two monoclonal antibodies | Q35982216 | ||
| Levels of expression of the mdr1 gene and glutathione S-transferase genes 2 and 3 and response to chemotherapy in multiple myeloma | Q35993668 | ||
| Quantitative determination of mdr1 gene expression in leukaemic cells from patients with acute leukaemia | Q35994137 | ||
| Rhodamine123 reveals heterogeneity within murine Lin-, Sca-1+ hemopoietic stem cells | Q36231382 | ||
| The role of topoisomerase II in drug resistance | Q36389510 | ||
| Overcoming multidrug resistance in Chinese hamster ovary cells in vitro by cyclosporin A (Sandimmune) and non-immunosuppressive derivatives | Q36467823 | ||
| Various methods of analysis of mdr-1/P-glycoprotein in human colon cancer cell lines | Q44513816 | ||
| Serial transplantation shows that early hematopoietic precursor cells are transduced by MDR-1 retroviral vector in a mouse gene therapy model | Q44547314 | ||
| High expression of the mdr3 multidrug-resistance gene in advanced-stage chronic lymphocytic leukemia | Q44596137 | ||
| Relationship of the expression of the multidrug resistance gene product (P-glycoprotein) in human colon carcinoma to local tumor aggressiveness and lymph node metastasis | Q45020379 | ||
| Prediction of doxorubicin resistance in vitro in myeloma, lymphoma, and breast cancer by P-glycoprotein staining | Q45277795 | ||
| Transplantation of bone marrow cells from transgenic mice expressing the human MDR1 gene results in long-term protection against the myelosuppressive effect of chemotherapy in mice | Q45880815 | ||
| ATP and GTP as alternative energy sources for vinblastine transport by P-170 in KB-V1 plasma membrane vesicles | Q46403272 | ||
| Reversal by cefoperazone of resistance to etoposide, doxorubicin, and vinblastine in multidrug resistant human sarcoma cells | Q46679193 | ||
| Reversal of multi-drug resistance in human KB cell lines by structural analogs of verapamil | Q46908442 | ||
| Immunohistochemical detection of the multidrug transport protein P1 70 in human normal tissues and malignant lymphomas | Q48684788 | ||
| Expression of the Multidrug Transporter P-Glycoprotein and In Vitro Chemosensitivity: Correlation with In Vivo Response to Chemotherapy in Acute Myeloid Leukemia | Q50876287 | ||
| P-glycoprotein expression in human plasma cell myeloma: correlation with prior chemotherapy. | Q52402350 | ||
| MDR-1 expression and response to vincristine, doxorubicin, and dexamethasone chemotherapy in multiple myeloma refractory to alkylating agents. | Q52881061 | ||
| PCR-determined expression of the MDR1 gene in chronic lymphocytic leukemia | Q53024621 | ||
| Expression of the multidrug resistance gene in myeloid leukemias. | Q53510343 | ||
| Expression of the multidrug transporter, P-glycoprotein, in chronic myelogenous leukaemia cells in blast crisis. | Q53511590 | ||
| Reversal of drug resistance by erythromycin: erythromycin increases the accumulation of actinomycin D and doxorubicin in multidrug-resistant cells. | Q53827442 | ||
| Binding properties of monoclonal antibodies recognizing external epitopes of the human MDR1 P-glycoprotein. | Q54230854 | ||
| High expression of the multidrug resistance P-glycoprotein in high-risk myelodysplasia is associated with immature phenotype. | Q54237527 | ||
| Expression of the multidrug resistance-associated P-glycoprotein (P-170) in 59 cases of de novo acute lymphoblastic leukemia: prognostic implications. | Q54242225 | ||
| Induction of multidrug resistance in human cells by transient exposure to different chemotherapeutic drugs. | Q54242542 | ||
| Expression of P-glycoprotein and anionic glutathione S-transferase genes in non-Hodgkin's lymphoma. | Q54249311 | ||
| Flow cytometric analysis of P-glycoprotein in normal and leukemic cells | Q54263700 | ||
| N-(5,5-diacetoxypent-1-yl)doxorubicin: a new intensely potent doxorubicin analogue | Q54264175 | ||
| Modulation of multidrug-resistant multiple myeloma by cyclosporin. The Leukaemia Group of the EORTC and the HOVON | Q54265673 | ||
| MDR1 RNA expression is an independent prognostic factor in acute myeloid leukemia | Q54266039 | ||
| Increased effectiveness of liposome-encapsulated doxorubicin in multidrug-resistant-transgenic mice compared with free doxorubicin | Q54270056 | ||
| Chemotherapy and chemosensitization of transgenic mice which express the human multidrug resistance gene in bone marrow: efficacy, potency, and toxicity | Q54288161 | ||
| Multidrug resistance (mdr1) gene expression in adult acute leukemias: correlations with treatment outcome and in vitro drug sensitivity | Q54291455 | ||
| MDR1 gene expression and treatment outcome in acute myeloid leukemia. | Q54296196 | ||
| Differentiation dependent expression of P-glycoprotein in the normal and neoplastic human kidney | Q54309279 | ||
| Expression of the multidrug transporter, P-glycoprotein, in acute leukemia cells and correlation to clinical drug resistance. | Q54317490 | ||
| Expression of a human complementary DNA for the multidrug resistance gene in murine hematopoietic precursor cells with the use of retroviral gene transfer. | Q54318113 | ||
| Effects of reoxygenation on cells from hypoxic regions of solid tumors: anticancer drug sensitivity and metastatic potential. | Q54328095 | ||
| Distribution of multi-drug resistance-associated P-glycoprotein in normal and neoplastic human tissues. Analysis with 3 monoclonal antibodies recognizing different epitopes of the P-glycoprotein molecule | Q54338292 | ||
| Reciprocal correlation between expression of P-glycoprotein and accumulation of rhodamine 123 in human tumors. | Q54342080 | ||
| Effects of tumor necrosis factor on sensitive and multidrug resistant human leukemia and myeloma cell lines. | Q54343312 | ||
| Doxorubicin resistance in P388 leukemia--evidence for reduced drug influx. | Q54344619 | ||
| MDR1 gene expression in lung cancer. | Q54346895 | ||
| Multidrug resistance in haemopoietic cell lines, myelodysplastic syndromes and acute myeloblastic leukaemia. | Q54354144 | ||
| Drug-resistance in multiple myeloma and non-Hodgkin's lymphoma: detection of P-glycoprotein and potential circumvention by addition of verapamil to chemotherapy. | Q54356862 | ||
| Exploring multidrug resistance using rhodamine 123. | Q54365299 | ||
| Purification of the 170- to 180-kilodalton membrane glycoprotein associated with multidrug resistance. 170- to 180-kilodalton membrane glycoprotein is an ATPase. | Q54390050 | ||
| Immunocytochemical localization of P170 at the plasma membrane of multidrug-resistant human cells. | Q54396700 | ||
| Single cell analysis of daunomycin uptake and efflux in multidrug-resistant and -sensitive KB cells: effects of verapamil and other drugs. | Q54420023 | ||
| Increased vinblastine binding to membrane vesicles from multidrug-resistant KB cells. | Q54426490 | ||
| Markedly altered membrane transport and intracellular binding of vincristine in multidrug-resistant Chinese hamster cells selected for resistance to vinca alkaloids. | Q54433051 | ||
| Amiodarone-induced enhancement of doxorubicin and 4'-deoxydoxorubicin cytotoxicity to rat colon cancer cells in vitro and in vivo. | Q54433093 | ||
| Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance | Q59050857 | ||
| Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule | Q67700733 | ||
| Multidrug resistance mediated by P-glycoproteins | Q36521434 | ||
| The role of glutathione-dependent enzymes in drug resistance | Q36540883 | ||
| Expression of a human multidrug resistance cDNA (MDR1) in the bone marrow of transgenic mice: resistance to daunomycin-induced leukopenia | Q36762208 | ||
| Genetic transfer of non-P-glycoprotein-mediated multidrug resistance (MDR) in somatic cell fusion: dissection of a compound MDR phenotype | Q36957720 | ||
| Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis | Q37195950 | ||
| Transfer and expression of the human multiple drug resistance gene into live mice | Q37249173 | ||
| Tumor hypoxia, drug resistance, and metastases | Q38142553 | ||
| Exposure to lipophilic industrial solvents leads to increased P-glycoprotein expression in peripheral blood cells | Q38512228 | ||
| Mechanism of multidrug resistance | Q39469004 | ||
| Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum. | Q39596634 | ||
| Multiple-drug resistance in human cancer | Q39765553 | ||
| Multidrug resistance and mutagenesis | Q40484328 | ||
| Molecular analysis of the multidrug transporter | Q40535310 | ||
| Clinical trials of modulation of multidrug resistance. Pharmacokinetic and pharmacodynamic considerations | Q40618716 | ||
| P-glycoproteins: mediators of multidrug resistance | Q40708755 | ||
| Clinical trials of agents that reverse multidrug resistance. A literature review | Q40786414 | ||
| Clinical correlates of MDR1 (P-glycoprotein) gene expression in ovarian and small-cell lung carcinomas | Q41091016 | ||
| Characteristics of Multidrug Resistance in Plasmodium and Leishmania: Detection of P-Glycoprotein-Like Components | Q41134781 | ||
| Alternating versus hybrid MOPP-ABVD in Hodgkin’s disease: The Milan experience | Q41139162 | ||
| Ketoconazole effectively reverses multidrug resistance in highly resistant KB cells | Q41492388 | ||
| Fluorescent cellular indicators are extruded by the multidrug resistance protein. | Q41520976 | ||
| Subpopulations of normal peripheral blood and bone marrow cells express a functional multidrug resistant phenotype | Q41592100 | ||
| Effect of liposomes on P-glycoprotein function in multidrug resistant cells | Q41602930 | ||
| Collateral sensitivity to nitrosoureas in multidrug-resistant cells selected with verapamil | Q41603062 | ||
| Mdr1/P-glycoprotein, topoisomerase, and glutathione-S-transferase pi gene expression in primary and relapsed state adult and childhood leukaemias | Q41606250 | ||
| Active efflux of daunorubicin and adriamycin in sensitive and resistant sublines of P388 leukemia | Q41613500 | ||
| In vitro effect of P-glycoprotein (P-gp) modulators on drug sensitivity of leukemic progenitors (CFU-L) in acute myelogenous leukemia (AML) | Q41622634 | ||
| SDZ PSC 833, a non-immunosuppressive cyclosporine: its potency in overcoming P-glycoprotein-mediated multidrug resistance of murine leukemia | Q41639342 | ||
| Induction of multiple-drug resistance during anti-neoplastic chemotherapy in vitro | Q41660516 | ||
| Characterization of the human MDR3 P-glycoprotein and its recognition by P-glycoprotein-specific monoclonal antibodies | Q41684223 | ||
| Synergistic inhibition by verapamil and quinine of P-glycoprotein-mediated multidrug resistance in a human myeloma cell line model | Q41699684 | ||
| Efficient gene transfer in live mice using a unique retroviral packaging line | Q41711534 | ||
| Expression of P-glycoprotein in adult T-cell leukemia cells | Q41714839 | ||
| Synergistic effect of cyclosporin A and verapamil in overcoming vincristine resistance of multidrug-resistant cultured human leukemia cells | Q41727067 | ||
| Regulation of mdr RNA levels in response to cytotoxic drugs in rodent cells | Q41727345 | ||
| Combined use of cyclosporin A and verapamil in modulating multidrug resistance in human leukemia cell lines. | Q41734147 | ||
| Effect of transient hypoxia on sensitivity to doxorubicin in human and murine cell lines | Q41736961 | ||
| P-glycoprotein expression in plasma-cell myeloma is associated with resistance to VAD. | Q41788734 | ||
| Comparison of western blot analysis and immunocytochemical detection of P-glycoprotein in multidrug resistant cells | Q41955078 | ||
| Different types of non-P-glycoprotein mediated multiple drug resistance in children with relapsed acute lymphoblastic leukaemia | Q42281472 | ||
| Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins | Q42625821 | ||
| Kinetic evidence suggesting that the multidrug transporter differentially handles influx and efflux of its substrates. | Q42800356 | ||
| Transfer and expression of the human multidrug resistance gene in mouse erythroleukemia cells | Q42814062 | ||
| Elimination of drug-resistant myeloma tumor cell lines by monoclonal anti-P-glycoprotein antibody and rabbit complement | Q43512672 | ||
| Expression of the mdr3 gene in prolymphocytic leukemia: association with cyclosporin-A-induced increase in drug accumulation | Q43631965 | ||
| Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1 | Q43662819 | ||
| Immunohistochemical detection of P-glycoprotein: prognostic correlation in soft tissue sarcoma of childhood | Q43675408 | ||
| Deletion and insertion mutants of the multidrug transporter. | Q43716820 | ||
| Expression of the multidrug resistance gene product (P-glycoprotein) in myelodysplasia is associated with a stem cell phenotype | Q43718996 | ||
| Demonstration That CFTR Is a Chloride Channel by Alteration of Its Anion Selectivity | Q43847410 | ||
| Use of fluorescent dyes as molecular probes for the study of multidrug resistance | Q43915737 | ||
| Relevance of mdr1 gene expression in acute myeloid leukemia and comparison of different diagnostic methods | Q44134663 | ||
| Expression of multidrug resistance gene mdr1 mRNA in a subset of normal bone marrow cells | Q44186167 | ||
| Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes | Q44280015 | ||
| P433 | issue | 4 | |
| P921 | main subject | multiple drug resistance | Q643839 |
| P304 | page(s) | 159-171 | |
| P577 | publication date | 1994-10-01 | |
| P1433 | published in | Annals of Hematology | Q15766509 |
| P1476 | title | P-glycoprotein-mediated multidrug resistance in normal and neoplastic hematopoietic cells | |
| P478 | volume | 69 |
| Q37595188 | ABC drug transporters and immunity: novel therapeutic targets in autoimmunity and cancer |
| Q28078884 | Aldehyde dehydrogenase 2 in aplastic anemia, Fanconi anemia and hematopoietic stem cells |
| Q28343624 | Antifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug action |
| Q42802043 | Antisense inhibition of P-glycoprotein expression using peptide-oligonucleotide conjugates |
| Q41541083 | Classical multidrug resistance in acute myeloid leukaemia |
| Q43614306 | Combined action of PSC 833 (Valspodar), a novel MDR reversing agent, with mitoxantrone, etoposide and cytarabine in poor-prognosis acute myeloid leukemia |
| Q92408998 | Detection and quantification of Parascaris P-glycoprotein drug transporter expression with a novel mRNA hybridization technique |
| Q36141213 | Human hepatoma cells rich in P-glycoprotein are sensitive to aclarubicin and resistant to three other anthracyclines |
| Q73158363 | Immunohistochemical evidence that P-glycoprotein in non-small cell lung cancers is associated with shorter survival |
| Q34260591 | Immunosuppressive interactions among calcium channel antagonists and selected corticosteroids and macrolides using human whole blood lymphocytes |
| Q41734226 | In vivo model systems in P-glycoprotein-mediated multidrug resistance |
| Q28474030 | Inhibition of ABCB1 (MDR1) expression by an siRNA nanoparticulate delivery system to overcome drug resistance in osteosarcoma |
| Q39946545 | Inhibition of MDR1 gene expression by chimeric HNA antisense oligonucleotides |
| Q37159488 | Ixabepilone: a new microtubule-targeting agent for breast cancer |
| Q36585890 | Lipid-functionalized dextran nanosystems to overcome multidrug resistance in cancer: a pilot study |
| Q90781961 | Membrane bound IL-21 based NK cell feeder cells drive robust expansion and metabolic activation of NK cells |
| Q37761069 | Nanoparticles: a promising modality in the treatment of sarcomas. |
| Q43836964 | P-glycoprotein (P-gp) is upregulated in peripheral T-cell subsets from solid organ transplant recipients |
| Q33749785 | P-glycoprotein and drug therapy in organ transplantation |
| Q51744122 | Pharmacogenetics of toxicity of 5-fluorouracil, doxorubicin and cyclophosphamide chemotherapy in breast cancer patients. |
| Q54127650 | Selection and maintenance of multidrug-resistant cells. |
| Q40416179 | Stable suppression of MDR-1 gene using siRNA expression vector to reverse drug resistance in a human uterine sarcoma cell line |
| Q34417569 | Targeted therapies for high-risk acute myeloid leukemia |
| Q37791482 | The microtubule as a breast cancer target |
| Q39842390 | Tyrosine kinase inhibitors potentiate the cytotoxicity of MDR-substrate anticancer agents independent of growth factor receptor status in lung cancer cell lines. |
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