PCR-determined expression of the MDR1 gene in chronic lymphocytic leukemia

scientific article published on December 1, 1992

PCR-determined expression of the MDR1 gene in chronic lymphocytic leukemia is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/BF01836067
P698PubMed publication ID1360821

P2093author name stringR. Herrmann
D. Huhn
A. Neubauer
R. Böhmer
C. F. Rochlitz
E. de Kant
J. Oertel
I. Heide
P2860cites workCellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissuesQ24633406
Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteinsQ28116625
Localization of the human multiple drug resistance gene, MDR1, to 7q21.1Q28298881
Expression of mdr1 and mdr3 multidrug-resistance genes in human acute and chronic leukemias and association with stimulation of drug accumulation by cyclosporineQ33499728
Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reactionQ33796247
Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.Q34559072
Expression of a multidrug-resistance gene in human tumors and tissuesQ34586576
P-glycoprotein and multidrug resistance in cancer chemotherapy.Q38345745
Multiple drug resistance gene expression in human renal cell cancer is associated with the histologic subtypeQ39228336
Non-P-glycoprotein mediated mechanism for multidrug resistance precedes P-glycoprotein expression during in vitro selection for doxorubicin resistance in a human lung cancer cell lineQ41724047
P-glycoprotein expression in plasma-cell myeloma is associated with resistance to VAD.Q41788734
Is the mdr 1 gene relevant in chronic lymphocytic leukemia?Q42465255
Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell linesQ42818012
Overexpression of the mdr1 gene in blast cells from patients with acute myelocytic leukemia is associated with decreased anthracycline accumulation that can be restored by cyclosporin-A.Q43420831
The role of the MDR-1/P-170 mechanism in the development of multidrug resistance in chronic myeloid leukemia.Q44071455
High expression of the mdr3 multidrug-resistance gene in advanced-stage chronic lymphocytic leukemiaQ44596137
Multidrug resistance (MDR 1) in leukemia: is it time to test?Q44818043
Increased P-glycoprotein expression and multidrug-resistant gene (mdr1) amplification are infrequently found in fresh acute leukemia cells. Sequential analysis of 15 cases at initial presentation and relapsed stageQ45331742
Expression of the multidrug resistance gene in myeloid leukemias.Q53510343
Expression of the multidrug transporter, P-glycoprotein, in chronic myelogenous leukaemia cells in blast crisis.Q53511590
Multidrug resistance (mdr1) gene expression in adult acute leukemias: correlations with treatment outcome and in vitro drug sensitivityQ54291455
MDR1 gene expression and treatment outcome in acute myeloid leukemia.Q54296196
The expression of the multidrug resistance-associated glycoprotein in B-cell chronic lymphocytic leukaemiaQ54299681
High risk of early resistant relapse for leukaemic patients with presence of multidrug resistance associated P-glycoprotein positive cells in complete remission.Q54309308
Reversal of drug-resistance by cyclosporin-A in a patient with acute myelocytic leukaemia.Q54322223
Expression of the mdr-1/P-170 gene in patients with acute lymphoblastic leukemia.Q54345353
Multidrug resistance in haemopoietic cell lines, myelodysplastic syndromes and acute myeloblastic leukaemia.Q54354144
Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistanceQ59050857
Clinical significance of multidrug resistance P-glycoprotein expression on acute nonlymphoblastic leukemia cells at diagnosisQ67894802
Analysis of multidrug resistance (MDR-1) gene expression in chronic lymphocytic leukaemia (CLL)Q68000093
Rapid analysis and purification of polymerase chain reaction products by high-performance liquid chromatographyQ68824122
Expression of a multidrug resistance gene in human cancersQ69366790
Immunohistochemical detection of P-glycoprotein in human tumor cells with a low degree of drug resistanceQ69367628
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectgene expressionQ26972
leukemiaQ29496
lymphocyteQ715347
P304page(s)241-246
P577publication date1992-12-01
P1433published inAnnals of HematologyQ15766509
P1476titlePCR-determined expression of the MDR1 gene in chronic lymphocytic leukemia
P478volume65

Reverse relations

cites work (P2860)
Q40534105Antibodies in the study of multiple drug resistance
Q53017876Detection of allelic loss within the beta 1-interferon gene in childhood acute lymphoblastic leukemia using differential PCR.
Q86525182Different frequencies and effects of ABCB1 T3435C polymorphism on clinical and laboratory features of B cell chronic lymphocytic leukemia in Kurdish patients
Q54426860MDR-1 polymorphisms (G2677T and C3435T) in B-chronic lymphocytic leukemia: an impact on susceptibility and prognosis.
Q71740233MDR1 expression correlates with mutant p53 expression in colorectal cancer metastases
Q40464059P-glycoprotein in Adult Hematologic Malignancies
Q45871082P-glycoprotein-mediated multidrug resistance in normal and neoplastic hematopoietic cells
Q78156200Transforming growth factor-beta and multidrug resistance in chronic lymphocytic leukemia

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