scholarly article | Q13442814 |
P356 | DOI | 10.1007/BF01209030 |
P698 | PubMed publication ID | 8898977 |
P50 | author | Christian Thiede | Q42323747 |
P2093 | author name string | R Herrmann | |
E de Kant | |||
C F Rochlitz | |||
I Heide | |||
P2860 | cites work | Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues | Q24633406 |
p53 gene mutation in B-cell chronic lymphocytic leukemia is associated with drug resistance and is independent of MDR1/MDR3 gene expression | Q27853401 | ||
Expression of a multidrug-resistance gene in human tumors and tissues | Q34586576 | ||
P-glycoprotein is not expressed in a majority of colorectal carcinomas and is not regulated by mutant p53 in vivo | Q36081542 | ||
Multiple drug resistance gene expression in human renal cell cancer is associated with the histologic subtype | Q39228336 | ||
The multidrug transporter, a double-edged sword | Q39469668 | ||
The region 3' to the major transcriptional start site of the MDR1 downstream promoter mediates activation by a subset of mutant P53 proteins | Q41260571 | ||
Wild-type but not mutant p53 can repress transcription initiation in vitro by interfering with the binding of basal transcription factors to the TATA motif | Q41555610 | ||
c-Myc trans-activates the p53 promoter through a required downstream CACGTG motif | Q41574272 | ||
Modulation of activity of the promoter of the human MDR1 gene by Ras and p53. | Q41643433 | ||
Analysis of the Chinese hamster P-glycoprotein/multidrug resistance gene pgp1 reveals that the AP-1 site is essential for full promoter activity | Q41668137 | ||
Constitutive expression of multidrug resistance in human colorectal tumours and cell lines | Q42389991 | ||
P-glycoprotein, HER-2/neu, and mutant p53 expression in human gynecologic tumors | Q42491214 | ||
Relationship of the expression of the multidrug resistance gene product (P-glycoprotein) in human colon carcinoma to local tumor aggressiveness and lymph node metastasis | Q45020379 | ||
Position specificity of Ki-ras oncogene mutations during the progression of colorectal carcinoma. | Q53023758 | ||
PCR-determined expression of the MDR1 gene in chronic lymphocytic leukemia | Q53024621 | ||
Transformation of rat liver epithelial cells with v-H-ras or v-raf causes expression of MDR-1, glutathione-S-transferase-P and increased resistance to cytotoxic chemicals. | Q53519384 | ||
The core promoter region of the P-glycoprotein gene is sufficient to confer differential responsiveness to wild-type and mutant p53. | Q54238383 | ||
P-glycoprotein associated expression of c-fos and c-jun products in human lung carcinomas. | Q54246959 | ||
MDR1 gene expression in lung cancer. | Q54346895 | ||
Down-regulation of ras and myc expression associated with mdr-1 overexpression in adriamycin-resistant tumor cells | Q67890183 | ||
Immunocytochemical detection of oncoproteins in animal and human tumor lines with acquired or inherent multidrug resistance | Q67958977 | ||
p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis | Q68623436 | ||
Expression of a multidrug resistance gene in human cancers | Q69366790 | ||
Evidence for a mutual regulation of p53 and c-myc expression in human colorectal cancer metastases | Q71375252 | ||
Relationship between p53 gene mutations and multidrug resistance (mdr1) gene expression in myelodysplastic syndromes | Q72656838 | ||
Wild type p53 stimulates expression from the human multidrug resistance promoter in a p53-negative cell line | Q95822405 | ||
P433 | issue | 11 | |
P921 | main subject | colorectal cancer | Q188874 |
colorectal carcinoma | Q25493920 | ||
cancer metastasis | Q120912394 | ||
P304 | page(s) | 671-675 | |
P577 | publication date | 1996-01-01 | |
P1433 | published in | Journal of Cancer Research and Clinical Oncology | Q2081599 |
P1476 | title | MDR1 expression correlates with mutant p53 expression in colorectal cancer metastases | |
P478 | volume | 122 |
Q38986437 | A cisplatin-resistant head and neck cancer cell line with cytoplasmic p53(mut) exhibits ATP-binding cassette transporter upregulation and high glutathione levels. |
Q40077983 | Ad-PUMA sensitizes drug-resistant choriocarcinoma cells to chemotherapeutic agents |
Q49485946 | Association between MDR1 C3435T polymorphism and colorectal cancer risk: A meta-analysis |
Q64086618 | Glucose starvation induces resistance to metformin through the elevation of mitochondrial multidrug resistance protein 1 |
Q48168333 | Relationship between expression of multiple drug resistance proteins and p53 tumor suppressor gene proteins in human brain astrocytes |