P-glycoprotein is not expressed in a majority of colorectal carcinomas and is not regulated by mutant p53 in vivo

scientific article

P-glycoprotein is not expressed in a majority of colorectal carcinomas and is not regulated by mutant p53 in vivo is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/BJC.1995.329
P932PMC publication ID2034003
P698PubMed publication ID7640210
P5875ResearchGate publication ID15559364

P50authorRagnhild A. LotheQ11996941
P2093author name stringChen Y
Clausen OP
De Angelis P
Lehne G
Stokke T
Smedshammer L
P2860cites workIsolation and expression of a complementary DNA that confers multidrug resistanceQ24295219
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
p53 gene mutation in B-cell chronic lymphocytic leukemia is associated with drug resistance and is independent of MDR1/MDR3 gene expressionQ27853401
Separation of drug transport and chloride channel functions of the human multidrug resistance P-glycoproteinQ28188274
Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reactionQ33796247
Expression of a multidrug-resistance gene in human tumors and tissuesQ34586576
Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastineQ34620070
MDR1 gene expression in primary colorectal carcinomasQ35977393
Understanding anticancer drug resistance: opportunities for modulation and impact on new drug designQ36022425
Clinical implications of multidrug resistance to chemotherapyQ36546687
Constant denaturant gel electrophoresis as a rapid screening technique for p53 mutationsQ37597399
Glutathione S-transferases: role in alkylating agent resistance and possible target for modulation chemotherapy--a review.Q37955790
DNA flow cytometry in solid tumors: practical aspects and clinical applications.Q38604398
Direct solid phase sequencing of genomic and plasmid DNA using magnetic beads as solid support.Q40451069
Consensus review of the clinical utility of DNA flow cytometry in colorectal cancerQ40836534
Flow cytometric analysis of multidrug-resistance-associated antigen (P-glycoprotein) and DNA ploidy in human colon cancerQ41090493
Modulation of activity of the promoter of the human MDR1 gene by Ras and p53.Q41643433
Protein kinase C phosphorylates P-glycoprotein in multidrug resistant human KB carcinoma cells.Q41734532
Constitutive expression of multidrug resistance in human colorectal tumours and cell linesQ42389991
Phosphorylation of the Mr 170,000 to 180,000 glycoprotein specific to multidrug-resistant tumor cells: effects of verapamil, trifluoperazine, and phorbol esters.Q42522544
Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissuesQ48913115
The grading of rectal cancer: historical perspectives and a multivariate analysis of 447 cases.Q52641814
Drug-metabolizing enzyme expression in human normal, peritumoral and tumoral colorectal tissue samples.Q53498685
Detection of P-glycoprotein in solid tumors by flow cytometry.Q54228205
Expression of drug-metabolizing enzymes and P-170 glycoprotein in colorectal carcinoma and normal mucosaQ54265683
Assessment of P-glycoprotein, glutathione-based detoxifying enzymes and O6-alkylguanine-DNA alkyltransferase as potential indicators of constitutive drug resistance in human colorectal tumorsQ54698089
Stabilised p53 facilitates aneuploid clonal divergence in colorectal cancerQ58423655
Enhanced expression of glutathione S-transferases in colorectal carcinoma compared to non-neoplastic mucosaQ64445217
Expression of a multidrug resistance gene in human cancersQ69366790
Glutathione S-transferases in normal and malignant human colon tissueQ70141022
Screening for TP53 mutations in osteosarcomas using constant denaturant gel electrophoresis (CDGE)Q70484971
Relationship between p53 gene mutations and multidrug resistance (mdr1) gene expression in myelodysplastic syndromesQ72656838
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)307-311
P577publication date1995-08-01
P1433published inBritish Journal of CancerQ326309
P1476titleP-glycoprotein is not expressed in a majority of colorectal carcinomas and is not regulated by mutant p53 in vivo
P478volume72

Reverse relations

cites work (P2860)
Q38986437A cisplatin-resistant head and neck cancer cell line with cytoplasmic p53(mut) exhibits ATP-binding cassette transporter upregulation and high glutathione levels.
Q37208654A new mdr-1 encoded P-170 specific monoclonal antibody: (6/1C) on paraffin wax embedded tissue without pretreatment of sections.
Q37641452Apoptosis and expression of Bax, Bcl-x, and Bcl-2 apoptotic regulatory proteins in colorectal carcinomas, and association with p53 genotype/phenotype
Q34580489Cancer chemoresistance: the relationship between p53 and multidrug transporters
Q64927462Changes in P-glycoprotein expression in gastric carcinoma with respect to distant gastric mucosa may be influenced by p53.
Q36617839Chromosomal gains and losses in primary colorectal carcinomas detected by CGH and their associations with tumour DNA ploidy, genotypes and phenotypes
Q35556544Decreased functional activity of multidrug resistance protein in primary colorectal cancer
Q34742986Expression of P-glycoprotein and p53 in advanced hepatocellular carcinoma treated by single agent chemotherapy: clinical correlation
Q37218281Expression of P-glycoprotein in hepatocellular carcinoma: a potential marker of prognosis
Q54125615Expression of P-glycoprotein, a multidrug-resistance gene product, is induced by radiotherapy in patients with oral squamous cell carcinoma.
Q36115974Expression of the multidrug resistance-associated protein (MRP) gene in colorectal carcinomas
Q71740233MDR1 expression correlates with mutant p53 expression in colorectal cancer metastases
Q44672133Modulation of doxorubicin sensitivity by a novel organic compound, oxalyl bis (N-phenyl) hydroxamic acid on acetyl aminofluorene-induced preneoplastic hepatocytes
Q40788757Mutant p53 cooperates with ETS and selectively up-regulates human MDR1 not MRP1.
Q35550932Overcoming Antiapoptotic Responses to Promote Chemosensitivity in Metastatic Colorectal Cancer to the Liver
Q41129549P53 protein expression in human multidrug-resistant CEM lymphoblasts
Q73184474Prognostic significance of DNA ploidy, S-phase fraction, and P-glycoprotein expression in colorectal cancer
Q74531411Proliferation-dependent expression and phosphorylation of pRB in B cell non-Hodgkin's lymphomas: dependence on RB1 copy number
Q35159123Regulation of expression of the multidrug resistance protein MRP1 by p53 in human prostate cancer cells
Q47370432Synthetically lethal nanoparticles for treatment of endometrial cancer.
Q33516216Visualization and enrichment of live putative cancer stem cell populations following p53 inactivation or Bax deletion using non-toxic fluorescent dyes.

Search more.