| P50 | author | Mohammad Salem | Q51076077 |
| | Ole Haagen Nielsen | Q37836698 |
| | Jakob Benedict Seidelin | Q37841713 |
| P2093 | author name string | Kris Nys | |
| | Mette Ammitzboell | |
| P2860 | cites work | Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein | Q22003920 |
| | A Nonsynonymous SNP in ATG16L1 Predisposes to Ileal Crohn’s Disease and Is Independent of CARD15 and IBD5 | Q22250941 |
| | Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease | Q22251069 |
| | Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease | Q22251082 |
| | XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease | Q22252318 |
| | Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis | Q24294860 |
| | The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes | Q24305372 |
| | Ambra1 regulates autophagy and development of the nervous system | Q24313508 |
| | Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages | Q24318814 |
| | Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci | Q24618592 |
| | The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy | Q24647053 |
| | FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells | Q24648105 |
| | Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis | Q24656576 |
| | Association of the T300A non-synonymous variant of the ATG16L1 gene with susceptibility to paediatric Crohn's disease | Q24673589 |
| | Contribution of IL23R but not ATG16L1 to Crohn's disease susceptibility in Koreans. | Q46561609 |
| | Mutations in the NOD2/CARD15 gene in Crohn's disease are associated with ileocecal resection and are a risk factor for reoperation | Q47608059 |
| | Defects in autophagy favour adherent-invasive Escherichia coli persistence within macrophages leading to increased pro-inflammatory response. | Q50503026 |
| | Sirolimus ameliorates inflammatory responses by switching the regulatory T/T helper type 17 profile in murine colitis. | Q51825944 |
| | Loss of Dictyostelium ATG9 results in a pleiotropic phenotype affecting growth, development, phagocytosis and clearance and replication of Legionella pneumophila. | Q51918047 |
| | Host cell autophagy activated by antibiotics is required for their effective antimycobacterial drug action. | Q52737808 |
| | Many inflammatory bowel disease risk loci include regions that regulate gene expression in immune cells and the intestinal epithelium. | Q54447794 |
| | Autophagy 16-like 1 rs2241880 G allele is associated with Crohn's disease in German children. | Q54470443 |
| | Genetic association and functional role of Crohn disease risk alleles involved in microbial sensing, autophagy, and endoplasmic reticulum (ER) stress. | Q54577917 |
| | Genetic variation in the autophagy gene ULK1 and risk of Crohn's disease. | Q55054234 |
| | ATG16L1andIL23RAre Associated With Inflammatory Bowel Diseases but Not With Celiac Disease in The Netherlands | Q56968779 |
| | IL23R R381Q and ATG16L1 T300A Are Strongly Associated With Crohn's Disease in a Study of New Zealand Caucasians With Inflammatory Bowel Disease | Q57154975 |
| | TheATG16L1Gene Variants rs2241879 and rs2241880 (T300A) Are Strongly Associated With Susceptibility to Crohn's Disease in the German Population | Q60689143 |
| | T300A Variant of Autophagy ATG16L1 Gene is Associated with Decreased Antigen Sampling and Processing by Dendritic Cells in Pediatric Crohnʼs Disease | Q61387912 |
| | Autophagy genes variants and paediatric Crohn's disease phenotype: A single-centre experience | Q61629097 |
| | Autophagy gene ATG16L1 but not IRGM is associated with Crohn's disease in Canadian children | Q79792559 |
| | Therapeutic effect of a new immunosuppressive agent, everolimus, on interleukin-10 gene-deficient mice with colitis | Q80165547 |
| | Autophagy gene ATG16L1 influences susceptibility and disease location but not childhood-onset in Crohn's disease in Northern Europe | Q80220052 |
| | [Correlation of the autophagosome gene ATG16L1 polymorphism and inflammatory bowel disease] | Q81318342 |
| | Abnormal activation of autophagy-induced crinophagy in Paneth cells from patients with Crohn's disease | Q83348629 |
| | Autophagy attenuates the adaptive immune response by destabilizing the immunologic synapse | Q83523684 |
| | Impaired autophagy leads to abnormal dendritic cell-epithelial cell interactions | Q84976087 |
| | Participation of lysosomes in cellular autophagy induced in rat liver by glucagon | Q24682852 |
| | Autophagy in the immune system | Q26859005 |
| | The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy | Q27933717 |
| | Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast | Q27934020 |
| | A ubiquitin-like system mediates protein lipidation | Q27934137 |
| | Identification of stem cells in small intestine and colon by marker gene Lgr5 | Q28131701 |
| | Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate | Q28187453 |
| | LC3 and GATE-16 N termini mediate membrane fusion processes required for autophagosome biogenesis | Q28235680 |
| | Atg8: an autophagy-related ubiquitin-like protein family | Q28246433 |
| | Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients | Q28304174 |
| | To be or not to be? How selective autophagy and cell death govern cell fate | Q28385846 |
| | Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis | Q28472412 |
| | AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 | Q28506431 |
| | Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations | Q28943541 |
| | Developmental expression of LC3α and β: Absence of fibronectin or autophagy phenotype in LC3β knockout mice | Q29028461 |
| | Autophagy: from phenomenology to molecular understanding in less than a decade | Q29614174 |
| | How to interpret LC3 immunoblotting | Q29614175 |
| | Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production | Q29614472 |
| | A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells | Q29614565 |
| | A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1 | Q29614873 |
| | NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation | Q29615617 |
| | Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry | Q29615618 |
| | Autophagy in human health and disease | Q29620121 |
| | An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure | Q30484302 |
| | Paneth cells as a site of origin for intestinal inflammation. | Q30559414 |
| | Genomic ATG16L1 risk allele-restricted Paneth cell ER stress in quiescent Crohn's disease | Q31126786 |
| | Cellular differentiation in the kidneys of newborn mice studies with the electron microscope. | Q31162064 |
| | Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant | Q33375721 |
| | Disease phenotype and genotype are associated with shifts in intestinal-associated microbiota in inflammatory bowel diseases | Q33691828 |
| | Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense | Q33694792 |
| | NOD2/CARD15, ATG16L1 and IL23R gene polymorphisms and childhood-onset of Crohn's disease | Q33782065 |
| | Human autophagy gene ATG16L1 is post-transcriptionally regulated by MIR142-3p | Q33831324 |
| | Inflammasome-independent modulation of cytokine response by autophagy in human cells | Q33872210 |
| | ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis | Q34258672 |
| | Diverse autophagosome membrane sources coalesce in recycling endosomes. | Q34370963 |
| | Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation | Q34684708 |
| | Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK. | Q34720900 |
| | Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology | Q40390478 |
| | Syntaxin 17: the autophagosomal SNARE. | Q41510414 |
| | mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6. | Q41792378 |
| | Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation | Q41792404 |
| | Atg16L2, a novel isoform of mammalian Atg16L that is not essential for canonical autophagy despite forming an Atg12–5-16L2 complex | Q41879755 |
| | Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection | Q41882233 |
| | A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease | Q41904813 |
| | A deficiency in the autophagy gene Atg16L1 enhances resistance to enteric bacterial infection | Q42042222 |
| | Vacuolating cytotoxin and variants in Atg16L1 that disrupt autophagy promote Helicobacter pylori infection in humans. | Q42134594 |
| | 'Nodophagy': New crossroads in Crohn disease pathogenesis | Q42575628 |
| | Genetic susceptibility to increased bacterial translocation influences the response to biological therapy in patients with Crohn's disease. | Q44784148 |
| | ATG16L1 gene polymorphisms are associated with palmoplantar pustulosis | Q45192665 |
| | Use of sirolimus (rapamycin) to treat refractory Crohn's disease | Q46417377 |
| | A multicenter, randomized, double-blind trial of everolimus versus azathioprine and placebo to maintain steroid-induced remission in patients with moderate-to-severe active Crohn's disease | Q46451550 |
| | ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase. | Q34728044 |
| | A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy | Q34962715 |
| | Genetic variants synthesize to produce paneth cell phenotypes that define subtypes of Crohn's disease. | Q35001662 |
| | Association between variants of the autophagy related gene--IRGM and susceptibility to Crohn's disease and ulcerative colitis: a meta-analysis | Q35043154 |
| | Transmission distortion in Crohn's disease risk gene ATG16L1 leads to sex difference in disease association | Q35190571 |
| | Autophagy suppresses interleukin-1β (IL-1β) signaling by activation of p62 degradation via lysosomal and proteasomal pathways. | Q35763237 |
| | Pattern recognition receptor and autophagy gene variants are associated with development of antimicrobial antibodies in Crohn's disease | Q36162274 |
| | Autophagic control of listeria through intracellular innate immune recognition in drosophila | Q36925388 |
| | Intestinal epithelium and autophagy: partners in gut homeostasis | Q37205898 |
| | Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2. | Q37297383 |
| | Autophagy genes protect against Salmonella typhimurium infection and mediate insulin signaling-regulated pathogen resistance | Q37318302 |
| | Autophagy regulation by nutrient signaling | Q37429067 |
| | Inflammatory bowel disease: pathogenesis | Q37454586 |
| | Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease | Q37539279 |
| | ATG16L1 and NOD2 polymorphisms enhance phagocytosis in monocytes of Crohn's disease patients | Q37629690 |
| | Muramyl dipeptide responsive pathways in Crohn's disease: from NOD2 and beyond | Q38070410 |
| | Evolution of the unfolded protein response. | Q38078141 |
| | Autophagy: a new target or an old strategy for the treatment of Crohn's disease? | Q38099513 |
| | Biology and trafficking of ATG9 and ATG16L1, two proteins that regulate autophagosome formation | Q38106561 |
| | Autophagosome formation--the role of ULK1 and Beclin1-PI3KC3 complexes in setting the stage. | Q38111131 |
| | A current perspective of autophagosome biogenesis | Q38168065 |
| | Historical landmarks of autophagy research | Q38173674 |
| | Debug Your Bugs - How NLRs Shape Intestinal Host-Microbe Interactions | Q38177269 |
| | mTOR and autophagy: a dynamic relationship governed by nutrients and energy. | Q38243394 |
| | A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3. | Q39022431 |
| | The protein ATG16L1 suppresses inflammatory cytokines induced by the intracellular sensors Nod1 and Nod2 in an autophagy-independent manner | Q39062783 |
| | Crohn's disease-associated adherent invasive Escherichia coli modulate levels of microRNAs in intestinal epithelial cells to reduce autophagy | Q39073755 |
| | Regulation of inflammatory response by 3-methyladenine involves the coordinative actions on Akt and glycogen synthase kinase 3β rather than autophagy | Q39279946 |
| | ATG16L1 meets ATG9 in recycling endosomes: additional roles for the plasma membrane and endocytosis in autophagosome biogenesis. | Q39394984 |
| | Measurement of autophagy in cells and tissues. | Q39668718 |
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 585-594 | |
| P577 | publication date | 2015-04-03 | |
| P1433 | published in | Autophagy | Q1255295 |
| P1476 | title | ATG16L1: A multifunctional susceptibility factor in Crohn disease | |
| P478 | volume | 11 | |