The microRNA-29 family in cartilage homeostasis and osteoarthritis

scientific journal article

The microRNA-29 family in cartilage homeostasis and osteoarthritis is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1023007892
P356DOI10.1007/S00109-015-1374-Z
P3181OpenCitations bibliographic resource ID4045514
P932PMC publication ID4856728
P698PubMed publication ID26687115
P5875ResearchGate publication ID287791501

P50authorTamas DalmayQ54997535
Tonia L VincentQ61070987
David Alan YoungQ44462616
P2093author name stringIan M Clark
Simon T Donell
Tracey E Swingler
Anne M Delany
Matthew J Barter
Linh T T Le
Natalie Crowe
P2860cites workConstitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinomaQ24336272
MicroRNAs: target recognition and regulatory functionsQ24609584
Emerging regulators of the inflammatory process in osteoarthritisQ26829840
Targets, models and challenges in osteoarthritis researchQ26850147
A pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturationQ26995910
Bone-cartilage interface crosstalk in osteoarthritis: potential pathways and future therapeutic strategiesQ27006808
Regulation of microRNA biogenesisQ28243976
The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6Q28593218
miRBase: annotating high confidence microRNAs using deep sequencing dataQ28660701
Integration of gene expression data with network-based analysis to identify signaling and metabolic pathways regulated during the development of osteoarthritisQ30778307
MicroRNA-140 plays dual roles in both cartilage development and homeostasisQ33885698
miR-29 suppression of osteonectin in osteoblasts: regulation during differentiation and by canonical Wnt signalingQ33923106
The roles of catabolic factors in the development of osteoarthritisQ34009214
Type II collagen expression is regulated by tissue-specific miR-675 in human articular chondrocytes.Q34042514
Sp1/NFkappaB/HDAC/miR-29b regulatory network in KIT-driven myeloid leukemiaQ34048276
miR-29 modulates Wnt signaling in human osteoblasts through a positive feedback loop.Q34055717
Smad proteins bind a conserved RNA sequence to promote microRNA maturation by DroshaQ34065396
Transcriptional suppression of mir-29b-1/mir-29a promoter by c-Myc, hedgehog, and NF-kappaB.Q34070947
Regulation of human chondrocyte function through direct inhibition of cartilage master regulator SOX9 by microRNA-145 (miRNA-145)Q34234586
The expression and function of microRNAs in chondrogenesis and osteoarthritis.Q34238501
Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritisQ34407611
Chondrocyte-specific microRNA-140 regulates endochondral bone development and targets Dnpep to modulate bone morphogenetic protein signaling.Q35096652
TGF-β/Smad3 signaling promotes renal fibrosis by inhibiting miR-29Q35142712
Emerging targets in osteoarthritis therapy.Q35752078
The miR-29 family: genomics, cell biology, and relevance to renal and cardiovascular injuryQ35786347
Detecting new microRNAs in human osteoarthritic chondrocytes identifies miR-3085 as a human, chondrocyte-selective, microRNA.Q35819840
Chondrogenesis, chondrocyte differentiation, and articular cartilage metabolism in health and osteoarthritisQ36111296
Genome-Wide MicroRNA and Gene Analysis of Mesenchymal Stem Cell Chondrogenesis Identifies an Essential Role and Multiple Targets for miR-140-5pQ36532581
SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen geneQ36567842
Chondrocyte miRNAs 221 and 483-5p respond to loss of matrix interaction by modulating proliferation and matrix synthesis.Q52962078
Restoration of the extracellular matrix in human osteoarthritic articular cartilage by overexpression of the transcription factor SOX9Q64377343
Differential Toll-like receptor-dependent collagenase expression in chondrocytesQ80656444
FOXO3A regulation by miRNA-29a Controls chondrogenic differentiation of mesenchymal stem cells and cartilage formationQ87171134
Experimental identification of microRNA-140 targets by silencing and overexpressing miR-140.Q36990769
NF-kappaB-YY1-miR-29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcomaQ37311506
Role of sox9 in growth factor regulation of articular chondrocytesQ37555671
Cartilage development and degeneration: a Wnt Wnt situationQ38020136
WNT signaling and cartilage: of mice and men.Q38065092
Wnt/β-catenin signalling: from plasma membrane to nucleusQ38076192
MicroRNA-29 family, a crucial therapeutic target for fibrosis diseasesQ38094545
Review: the role of microRNAs in osteoarthritis and chondrogenesisQ38105988
miRNAs: biogenesis, origin and evolution, functions on virus-host interactionQ38134596
Pathogenesis of post-traumatic OA with a view to interventionQ38209061
Fibroblast growth factor 2 drives changes in gene expression following injury to murine cartilage in vitro and in vivoQ38843439
Canonical Wnt signaling skews TGF-β signaling in chondrocytes towards signaling via ALK1 and Smad 1/5/8.Q39030668
Class I histone deacetylase inhibition modulates metalloproteinase expression and blocks cytokine-induced cartilage degradation.Q39168362
MicroRNA regulation associated chondrogenesis of mouse MSCs grown on polyhydroxyalkanoatesQ39526269
Analyzing mRNA expression identifies Smad3 as a microRNA-140 target regulated only at protein level.Q39752388
Isolation and characterization of CD146+ multipotent mesenchymal stromal cells.Q39978569
The cartilage specific microRNA-140 targets histone deacetylase 4 in mouse cellsQ40308810
The DF-1 chicken fibroblast cell line: transformation induced by diverse oncogenes and cell death resulting from infection by avian leukosis virusesQ41012360
Sox9 is upstream of microRNA-140 in cartilageQ42117754
Fibroblast growth factor 2 is an intrinsic chondroprotective agent that suppresses ADAMTS-5 and delays cartilage degradation in murine osteoarthritisQ42456204
Role of miR-146a in human chondrocyte apoptosis in response to mechanical pressure injury in vitroQ42733032
Sulforaphane represses matrix-degrading proteases and protects cartilage from destruction in vitro and in vivoQ43022838
The microRNA-producing enzyme Dicer1 is essential for zebrafish developmentQ47073131
The individual and socioeconomic impact of osteoarthritisQ47602911
Suppression of Wnt signaling by the miR-29 family is mediated by demethylation of WIF-1 in non-small-cell lung cancerQ47794745
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue5
P921main subjectosteoarthritisQ62736
microRNAQ310899
positive regulation of gene expressionQ14633893
transforming growth factor beta 1Q2062543
Nuclear factor kappa B subunit 1Q4044834
Interleukin 1 betaQ411529
cartilageQ502730
Wnt family member 3AQ21115939
SRY-box transcription factor 9Q21127264
P304page(s)583-596
P577publication date2015-12-19
P1433published inJournal of Molecular MedicineQ6295593
P1476titleThe microRNA-29 family in cartilage homeostasis and osteoarthritis
P478volume94

Reverse relations

cites work (P2860)
Q64957773Analysis of non‑alcoholic fatty liver disease microRNA expression spectra in rat liver tissues.
Q42362626Association between circulating miRNAs and spinal involvement in patients with axial spondyloarthritis.
Q92392859Association of circulating microRNAs with prevalent and incident knee osteoarthritis in women: the OFELY study
Q64100869Bax Targeted by miR-29a Regulates Chondrocyte Apoptosis in Osteoarthritis
Q89514218Bone mesenchymal stem cell-derived exosomal microRNA-29b-3p prevents hypoxic-ischemic injury in rat brain by activating the PTEN-mediated Akt signaling pathway
Q47161268Computer simulation models as a tool to investigate the role of microRNAs in osteoarthritis
Q55177192Cryptotanshinone Protects Cartilage against Developing Osteoarthritis through the miR-106a-5p/GLIS3 Axis.
Q47578652Cushioning the cartilage: a canonical Wnt restricting matter
Q36105915Decoding the Regulatory Landscape of Ageing in Musculoskeletal Engineered Tissues Using Genome-Wide DNA Methylation and RNASeq.
Q47142546Deduction of Novel Genes Potentially Involved in Osteoblasts of Rheumatoid Arthritis Using Next-Generation Sequencing and Bioinformatic Approaches.
Q52901753Downregulation of miR-221-3p contributes to IL-1β-induced cartilage degradation by directly targeting the SDF1/CXCR4 signaling pathway.
Q92802485Inhibition of microRNA-495 suppresses chondrocyte apoptosis through activation of the NF-κB signaling pathway by regulating CCL4 in osteoarthritis
Q48242753KDM6A promotes chondrogenic differentiation of periodontal ligament stem cells by demethylation of SOX9.
Q39630055Long noncoding RNA GIHCG promotes hepatocellular carcinoma progression through epigenetically regulating miR-200b/a/429.
Q33804362MicroRNA-29a Counteracts Synovitis in Knee Osteoarthritis Pathogenesis by Targeting VEGF.
Q58605183MicroRNA-29a-3p enhances dental implant osseointegration of hyperlipidemic rats via suppressing dishevelled 2 and frizzled 4
Q33762372MicroRNA-29b Contributes to Collagens Imbalance in Human Osteoarthritic and Dedifferentiated Articular Chondrocytes
Q58805128MicroRNAs and Osteoarthritis
Q52770564MicroRNAs and their variants in an RNA world: implications for complex interactions and diverse roles in an RNA regulatory network.
Q54963377MicroRNAs in orthopaedic research: Disease associations, potential therapeutic applications, and perspectives.
Q58800992Onset and Progression of Human Osteoarthritis-Can Growth Factors, Inflammatory Cytokines, or Differential miRNA Expression Concomitantly Induce Proliferation, ECM Degradation, and Inflammation in Articular Cartilage?
Q92558034Significant changes in synovial fluid microRNAs after high tibial osteotomy in medial compartmental knee osteoarthritis: Identification of potential prognostic biomarkers
Q47298168Subchondral mesenchymal stem cells from osteoarthritic knees display high osteogenic differentiation capacity through microRNA-29a regulation of HDAC4.
Q92236596TMF inhibits miR-29a/Wnt/β-catenin signaling through upregulating Foxo3a activity in osteoarthritis chondrocytes
Q90415332The Involvement of MicroRNAs in Osteoarthritis and Recent Developments: A Narrative Review
Q57043965The Potential Roles of CircRNAs in Osteoarthritis: A Coming Journey to Find a Treasure
Q38893214The Role of MicroRNAs and Their Targets in Osteoarthritis
Q28068811The Role of miRNAs in Common Inflammatory Arthropathies: Osteoarthritis and Gouty Arthritis
Q90372415The Transcription Factor-microRNA Regulatory Network during hESC-chondrogenesis
Q58760737The complex landscape of microRNAs in articular cartilage: biology, pathology, and therapeutic targets
Q104471823The role of microRNA-3085 in chondrocyte function
Q42379009miR-29b regulates expression of collagens I and III in chondrogenically differentiating BMSC in an osteoarthritic environment
Q64967939miRNA-101 promotes chondrogenic differentiation in rat bone marrow mesenchymal stem cells.

Search more.