MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils

scientific journal article

MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M313672200
P698PubMed publication ID15131124

P50authorEric HanssenQ42996213
P2093author name stringMark A Gibson
Emma Moore
Fan Hing Hew
P2860cites workFibrillin, a new 350-kD glycoprotein, is a component of extracellular microfibrilsQ24299279
The association of human fibulin-1 with elastic fibers: an immunohistological, ultrastructural, and RNA studyQ24306799
Further characterization of proteins associated with elastic fiber microfibrils including the molecular cloning of MAGP-2 (MP25)Q24316167
Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated proteinQ24317720
The gene for a human microfibril-associated glycoprotein is commonly deleted in Smith-Magenis syndrome patientsQ24321563
Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matricesQ24336069
The latent transforming growth factor beta binding protein (LTBP) familyQ24532213
Latent transforming growth factor-beta binding proteins (LTBPs)--structural extracellular matrix proteins for targeting TGF-beta actionQ28140281
Tropoelastin binding to fibulins, nidogen-2 and other extracellular matrix proteinsQ28146123
Molecular interactions of biglycan and decorin with elastic fiber components: biglycan forms a ternary complex with tropoelastin and microfibril-associated glycoprotein 1Q28207686
Protein interaction studies of MAGP-1 with tropoelastin and fibrillin-1Q28210209
Identification of a matrix-binding domain in MAGP1 and MAGP2 and intracellular localization of alternative splice formsQ28215811
Microfibril-associated glycoprotein-1 (MAGP-1) binds to the pepsin-resistant domain of the alpha3(VI) chain of type VI collagenQ28247738
Identification of a major microfibril-associated glycoprotein-1-binding domain in fibrillin-2Q28252785
Fibrillin-1 and fibulin-2 interact and are colocalized in some tissuesQ28284384
Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrilsQ28504747
Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndromeQ29618845
Quality control in the endoplasmic reticulumQ29619929
The EMILIN protein familyQ30610055
Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assemblyQ31097011
Fibrillin: from domain structure to supramolecular assemblyQ34078143
Differential expression of fibrillin-3 adds to microfibril variety in human and avian, but not rodent, connective tissuesQ34298597
Structure of the human gene encoding the associated microfibrillar protein (MFAP1) and localization to chromosome 15q15-q21.Q34317230
Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genesQ34592768
The microfibrillar proteins MAGP-1 and fibrillin-1 form a ternary complex with the chondroitin sulfate proteoglycan decorinQ34707917
Fibrillin-rich microfibrils: elastic biopolymers of the extracellular matrix.Q35144668
Bovine latent transforming growth factor beta 1-binding protein 2: molecular cloning, identification of tissue isoforms, and immunolocalization to elastin-associated microfibrilsQ36556405
Genomic organization of the sequence coding for fibrillin, the defective gene product in Marfan syndrome.Q36768408
Defective secretion of recombinant fragments of fibrillin-1: implications of protein misfolding for the pathogenesis of Marfan syndrome and related disordersQ40662043
Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differencesQ40690444
Microfibril-associated glycoprotein-2 specifically interacts with a range of bovine and human cell types via alphaVbeta3 integrinQ40957482
Fibrillln mutations in Marfan syndrome and related phenotypesQ41099958
Fibrillin-1: organization in microfibrils and structural propertiesQ41204597
The supramolecular organization of fibrillin-rich microfibrils.Q41883015
Molecular cloning of the microfibrillar protein MFAP3 and assignment of the gene to human chromosome 5q32-q33.2.Q42805748
Synthesis and structural organization of zonular fibers during development and agingQ46181778
Microfibril-associated glycoprotein-2 (MAGP-2) is specifically associated with fibrillin-containing microfibrils but exhibits more restricted patterns of tissue localization and developmental expression than its structural relative MAGP-1.Q47813935
Covalent and non-covalent interactions of betaig-h3 with collagen VI. Beta ig-h3 is covalently attached to the amino-terminal region of collagen VI in tissue microfibrils.Q53932209
P433issue28
P407language of work or nameEnglishQ1860
P304page(s)29185-29194
P577publication date2004-05-06
P1433published inJournal of Biological ChemistryQ867727
P1476titleMAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils
P478volume279

Reverse relations

cites work (P2860)
Q33641386Biogenesis and function of fibrillin assemblies
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Q33628905Defining elastic fiber interactions by molecular fishing: an affinity purification and mass spectrometry approach
Q87285382Elastic fibres in health and disease
Q54439202Enhanced fibrillin-2 expression is a general feature of wound healing and sclerosis: potential alteration of cell attachment and storage of TGF-beta.
Q38903109FBN1: The disease-causing gene for Marfan syndrome and other genetic disorders
Q42376279Fell-Muir Lecture: Fibrillin microfibrils: structural tensometers of elastic tissues?
Q36101310Fibrillin microfibrils
Q64077240Fibrillin microfibrils and elastic fibre proteins: Functional interactions and extracellular regulation of growth factors
Q89666788Hypoxia-induced MFAP5 Promotes Tumor Migration and Invasion via AKT Pathway in Head and Neck Squamous Cell Carcinoma
Q35742847LTBP-2 Has a Single High-Affinity Binding Site for FGF-2 and Blocks FGF-2-Induced Cell Proliferation.
Q42673678Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites
Q36755549MAGP2 controls Notch via interactions with RGD binding integrins: Identification of a novel ECM-integrin-Notch signaling axis.
Q33924430Microfibril structure masks fibrillin-2 in postnatal tissues
Q28509623Microfibril-associated MAGP-2 stimulates elastic fiber assembly
Q34025344Microfibril-associated glycoprotein-1, an extracellular matrix regulator of bone remodeling
Q28298567Microfibrillar proteins MAGP-1 and MAGP-2 induce Notch1 extracellular domain dissociation and receptor activation
Q39793330Microfibrils, elastin fibres and collagen fibres in the human intervertebral disc and bovine tail disc
Q41768833Molecular analysis of fibulin-5 function during de novo synthesis of elastic fibers
Q37682494Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice
Q37822821TB domain proteins: evolutionary insights into the multifaceted roles of fibrillins and LTBPs
Q37500188The microfibril-associated glycoproteins (MAGPs) and the microfibrillar niche
Q24656172The molecular genetics of Marfan syndrome and related disorders

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