Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice

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Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice is …
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scholarly articleQ13442814

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P356DOI10.1016/J.CELS.2016.10.016
P932PMC publication ID5338604
P698PubMed publication ID27866946

P50authorYibin WangQ40664206
Jessica WangQ56606124
Marc SantoliniQ56905625
Aldons Jake LusisQ60642067
Alain KarmaQ91716298
James N WeissQ93175069
Milagros C RomayQ117283400
Shuxun RenQ117283402
P2093author name stringChristoph D Rau
Mary Tuteryan
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Determination of the substrate repertoire of ADAMTS2, 3, and 14 significantly broadens their functions and identifies extracellular matrix organization and TGF-β signaling as primary targets.Q51572180
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P4510describes a project that useslimmaQ112236343
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcardiomyopathyQ847583
P304page(s)121-128.e4
P577publication date2016-11-16
P1433published inCell SystemsQ27726426
P1476titleSystems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice
P478volume4

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Q38597918A Systems Biology Approach to Investigating Sex Differences in Cardiac Hypertrophy.
Q50420738A personalized, multiomics approach identifies genes involved in cardiac hypertrophy and heart failure.
Q44234183A systems genetics approach identifies Trp53inp2 as a link between cardiomyocyte glucose utilization and hypertrophic response
Q92652905Isoproterenol-Induced Cardiac Diastolic Dysfunction in Mice: A Systems Genetics Analysis
Q89614848Mouse Systems Genetics as a Prelude to Precision Medicine
Q92409586Relevance of Multi-Omics Studies in Cardiovascular Diseases
Q58697049The Ca transient as a feedback sensor controlling cardiomyocyte ionic conductances in mouse populations
Q88461673Topological Arrangement of Cardiac Fibroblasts Regulates Cellular Plasticity

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