Transforming growth factor (TGF)-β signaling in cardiac remodeling.

scientific article

Transforming growth factor (TGF)-β signaling in cardiac remodeling. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YJMCC.2010.10.033
P932PMC publication ID3072437
P698PubMed publication ID21059352
P5875ResearchGate publication ID47717305

P50authorNikolaos G FrangogiannisQ56899107
P2093author name stringWei Chen
Marcin Dobaczewski
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Dilated cardiomyopathy is associated with significant changes in collagen type I/III ratioQ77822656
Inhibition of TGF-beta signaling exacerbates early cardiac dysfunction but prevents late remodeling after infarctionQ80987635
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TGF-beta receptor function in the endothelium.Q36017194
Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblastsQ36232642
Transforming growth factor-beta: a key mediator of fibrosisQ36239091
Increased vulnerability to atrial fibrillation in transgenic mice with selective atrial fibrosis caused by overexpression of TGF-beta1.Q36249250
Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growthQ36351780
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The role of TGF-beta signaling in myocardial infarction and cardiac remodelingQ36655326
Aging and remodeling during healing of the wounded heart: current therapies and novel drug targetsQ37130706
TGF-[beta]1 limits plaque growth, stabilizes plaque structure, and prevents aortic dilation in apolipoprotein E-null mice.Q37339703
Transforming growth factor-beta 3 is required for secondary palate fusionQ37373842
Transforming growth factor-beta receptor antagonism attenuates myocardial fibrosis in mice with cardiac-restricted overexpression of tumor necrosis factorQ37412421
Characterization of the inflammatory and fibrotic response in a mouse model of cardiac pressure overload.Q37434655
Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosisQ37591872
Thrombospondins in the heart: potential functions in cardiac remodelingQ37607128
Potential therapeutic targets for cardiac fibrosis: TGFbeta, angiotensin, endothelin, CCN2, and PDGF, partners in fibroblast activationQ37764239
Balancing the activation state of the endothelium via two distinct TGF-beta type I receptorsQ39646992
TGF-beta1 mediates the hypertrophic cardiomyocyte growth induced by angiotensin II.Q39737677
A synthetic peptide from transforming growth factor-beta1 type III receptor prevents myocardial fibrosis in spontaneously hypertensive ratsQ39914658
Angiotensin-converting enzyme inhibition and ventricular remodeling after myocardial infarctionQ40543293
Identification of an inhibitor targeting macrophage production of monocyte chemoattractant protein-1 as TGF-beta 1.Q41098186
Transforming growth factor-beta: vasculogenesis, angiogenesis, and vessel wall integrityQ41489951
Smad3 signaling critically regulates fibroblast phenotype and function in healing myocardial infarctionQ41769718
Effects of an AT1 receptor antagonist, an ACE inhibitor and a calcium channel antagonist on cardiac gene expressions in hypertensive ratsQ42098308
Association between transforming growth factor-beta(1) and left ventricular mass and diameter in hypertensive patientsQ43062936
Targeted inhibition of activin receptor-like kinase 5 signaling attenuates cardiac dysfunction following myocardial infarctionQ43162631
Effects of combination of angiotensin-converting enzyme inhibitor and angiotensin receptor antagonist on inflammatory cellular infiltration and myocardial interstitial fibrosis after acute myocardial infarctionQ43754711
Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrixQ43755354
Alterations of beta-adrenergic signaling and cardiac hypertrophy in transgenic mice overexpressing TGF-beta(1).Q44103977
Transforming growth factor beta inhibition increases mortality and left ventricular dilatation after myocardial infarctionQ44528242
Postinfarction gene therapy against transforming growth factor-beta signal modulates infarct tissue dynamics and attenuates left ventricular remodeling and heart failureQ45883186
Angiotensin II stimulates cardiac myocyte hypertrophy via paracrine release of TGF-beta 1 and endothelin-1 from fibroblastsQ46061333
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Essential role of Smad3 in infarct healing and in the pathogenesis of cardiac remodeling.Q52583103
Activation of the cardiac renin-angiotensin system and increased myocardial collagen expression in human aortic valve disease.Q52965082
TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice.Q64979026
P433issue4
P304page(s)600-606
P577publication date2010-11-06
P1433published inJournal of Molecular and Cellular CardiologyQ2061932
P1476titleTransforming growth factor (TGF)-β signaling in cardiac remodeling
P478volume51

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Q93025612Sex-Specific Aspects in the Pathophysiology and Imaging of Coronary Macro- and Microvascular Disease
Q61799680Sex-specific influence on cardiac structural remodeling and therapy in cardiovascular disease
Q95661032Single-cell analysis of murine fibroblasts identifies neonatal to adult switching that regulates cardiomyocyte maturation
Q35005754Smad3 inactivation and MiR-29b upregulation mediate the effect of carvedilol on attenuating the acute myocardium infarction-induced myocardial fibrosis in rat.
Q57490976Sodium Houttuyfonate Alleviates Post-infarct Remodeling in Rats via AMP-Activated Protein Kinase Pathway
Q38667881Specific α7 nicotinic acetylcholine receptor agonist ameliorates isoproterenol-induced cardiac remodeling in mice through TGF-β1/Smad3 pathway.
Q45953214Suramin attenuates dystrophin-deficient cardiomyopathy in the mdx mouse model of duchenne muscular dystrophy.
Q85522346Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress
Q38842278Syndecans in heart fibrosis
Q92644753Synergistic effect of estradiol and testosterone protects against IL-6-inducedcardiomyocyte apoptosismediated by TGF-β1
Q47152878Systemic inflammation is associated with myocardial fibrosis, diastolic dysfunction, and cardiac hypertrophy in patients with hypertrophic cardiomyopathy
Q37682494Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice
Q47369105T cell subsets: an integral component in pathogenesis of rheumatic heart disease
Q58794179TAK-272 (imarikiren), a novel renin inhibitor, improves cardiac remodeling and mortality in a murine heart failure model
Q87681974TGF-β Signaling in Control of Cardiovascular Function
Q92311732TGF-β inhibitor therapy decreases fibrosis and stimulates cardiac improvement in a pre-clinical study of chronic Chagas' heart disease
Q37899212TGF-β signaling in fibrosis
Q53508778TGF-β1 and TIMP-4 regulate atrial fibrosis in atrial fibrillation secondary to rheumatic heart disease.
Q64279254TGFβ1 and HGF regulate CTGF expression in human atrial fibroblasts and are involved in atrial remodelling in patients with rheumatic heart disease
Q35805680TSC-22 up-regulates collagen 3a1 gene expression in the rat heart
Q37100838Targeting inflammatory pathways in myocardial infarction.
Q38120799Targeting the chemokines in cardiac repair.
Q42590775Targeting the transforming growth factor (TGF)-β cascade in the remodeling heart: benefits and perils
Q36912426Telomerase expression confers cardioprotection in the adult mouse heart after acute myocardial infarction
Q53306185Temporal cardiac remodeling post-myocardial infarction: dynamics and prognostic implications in personalized medicine.
Q90765693The ATRQβ-001 vaccine improves cardiac function and prevents postinfarction cardiac remodeling in mice
Q38875774The Biological Basis for Cardiac Repair After Myocardial Infarction: From Inflammation to Fibrosis.
Q52562680The Effects of PPAR Stimulation on Cardiac Metabolic Pathways in Barth Syndrome Mice.
Q38675294The Janus face of myofibroblasts in the remodeling heart
Q34071933The Notch pathway controls fibrotic and regenerative repair in the adult heart
Q42694416The Processes and Mechanisms of Cardiac and Pulmonary Fibrosis
Q26744761The Role of Hyperglycemia and Insulin Resistance in the Development and Progression of Pulmonary Arterial Hypertension
Q48220874The Role of c-SKI in Regulation of TGFβ-Induced Human Cardiac Fibroblast Proliferation and ECM Protein Expression
Q33737254The Soft- and Hard-Heartedness of Cardiac Fibroblasts: Mechanotransduction Signaling Pathways in Fibrosis of the Heart
Q38044657The TGF-β pathway as an emerging target for Chagas disease therapy.
Q92654748The aqueous extract of Gentianella acuta improves isoproterenol‑induced myocardial fibrosis via inhibition of the TGF‑β1/Smads signaling pathway
Q89629055The association between microRNA-21 and hypertension-induced cardiac remodeling
Q90104612The axis of local cardiac endogenous Klotho-TGF-β1-Wnt signaling mediates cardiac fibrosis in human
Q33721878The calcium release-activated calcium channel Orai1 represents a crucial component in hypertrophic compensation and the development of dilated cardiomyopathy
Q35125156The complex regulation of tanshinone IIA in rats with hypertension-induced left ventricular hypertrophy
Q38407430The different role of sex hormones on female cardiovascular physiology and function: not only oestrogens
Q37341800The effect of losartan therapy on ventricular function in Marfan patients with haploinsufficient or dominant negative FBN1 mutations
Q38144845The immune system and the remodeling infarcted heart: cell biological insights and therapeutic opportunities.
Q35529656The inflammatory response in myocardial injury, repair, and remodelling.
Q53615353The liver X receptor agonist AZ876 protects against pathological cardiac hypertrophy and fibrosis without lipogenic side effects.
Q34807853The overexpression of Twinkle helicase ameliorates the progression of cardiac fibrosis and heart failure in pressure overload model in mice
Q37161329The pathogenesis of cardiac fibrosis.
Q27002949The physiology of cardiovascular disease and innovative liposomal platforms for therapy
Q92453964The relationship between myocardial fibrosis detected by cardiac magnetic resonance and Tp-e interval, 5-year sudden cardiac death risk score in hypertrophic cardiomyopathy patients
Q35065245The role of TGFβ1 and LRG1 in cardiac remodelling and heart failure.
Q38023271The role of TWEAK/Fn14 in cardiac remodeling
Q38034004The role of cardiac fibroblasts in the transition from inflammation to fibrosis following myocardial infarction
Q39265526The role of transforming growth factor (TGF)-β in the infarcted myocardium
Q53124136The transcardiac gradient of cardio-microRNAs in the failing heart.
Q55289622Therapeutic Potential of Polyphenols in Cardiac Fibrosis.
Q90643368Therapeutic Targets for the Treatment of Cardiac Fibrosis and Cancer: Focusing on TGF-β Signaling
Q35534242Thrombospondin-1 induction in the diabetic myocardium stabilizes the cardiac matrix in addition to promoting vascular rarefaction through angiopoietin-2 upregulation
Q54785371Tissue transglutaminase induction in the pressure-overloaded myocardium regulates matrix remodelling.
Q35923510Tomoregulin-1 prevents cardiac hypertrophy after pressure overload in mice by inhibiting TAK1-JNK pathways
Q87224605Transcriptional network analysis for the regulation of left ventricular hypertrophy and microvascular remodeling
Q48728454Transcriptional regulation of endothelial-to-mesenchymal transition in cardiac fibrosis: role of myocardin-related transcription factor A and activating transcription factor 3.
Q42247071Transforming growth factor β and its role in heart disease
Q34089713Transforming growth factor β receptor 1 is a new candidate prognostic biomarker after acute myocardial infarction
Q36549555Transforming growth factor-beta 1 produced by vascular smooth muscle cells predicts fibrosis in the gastrocnemius of patients with peripheral artery disease
Q96817489Ubiquitin C-terminal hydrolase L1 (UCHL1) regulates post-myocardial infarction cardiac fibrosis through glucose-regulated protein of 78 kDa (GRP78)
Q91971971Upregulation of Circular RNA CircNFIB Attenuates Cardiac Fibrosis by Sponging miR-433
Q50201254Vascularized Cardiac Spheroids as Novel 3D in vitro Models to Study Cardiac Fibrosis.
Q84788582Where are the new drugs to treat heart failure? Introduction to the special issue on "key signaling molecules in hypertrophy and heart failure"
Q92860289Zebrafish as a Smart Model to Understand Regeneration After Heart Injury: How Fish Could Help Humans
Q89938818miR-1-5p targets TGF-βR1 and is suppressed in the hypertrophying hearts of rats with pulmonary arterial hypertension
Q57823449miR-146a Suppresses SUMO1 Expression and Induces Cardiac Dysfunction in Maladaptive Hypertrophy
Q39413020miR-29b as a therapeutic agent for angiotensin II-induced cardiac fibrosis by targeting TGF-β/Smad3 signaling
Q90255266βIV-Spectrin/STAT3 complex regulates fibroblast phenotype, fibrosis, and cardiac function

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