IPW-5371 Proves Effective as a Radiation Countermeasure by Mitigating Radiation-Induced Late Effects

scientific article published in November 2016

IPW-5371 Proves Effective as a Radiation Countermeasure by Mitigating Radiation-Induced Late Effects is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1667/RR14403.2
P932PMC publication ID5278768
P698PubMed publication ID27841740

P2093author name stringAntonio Abbate
Ramesh Mullangi
Ross Mikkelsen
Eleonora Mezzaroma
Adolfo G Mauro
Barry Hart
Christopher Rabender
Mitchell Anscher
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Pentoxifylline inhibits transforming growth factor-beta signaling and renal fibrosis in experimental crescentic glomerulonephritis in ratsQ46446652
Kinetics of response to long-term treatment combining pentoxifylline and tocopherol in patients with superficial radiation-induced fibrosis.Q46784009
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Postmastectomy hypofractionated and accelerated radiation therapy with (and without) subcutaneous amifostine cytoprotection.Q51313107
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Cardiotoxicity after childhood cancer: beginning with the end in mindQ82833695
Oxymatrine attenuates bleomycin-induced pulmonary fibrosis in mice via the inhibition of inducible nitric oxide synthase expression and the TGF-β/Smad signaling pathwayQ83517786
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Heart irradiation as a risk factor for radiation pneumonitis.Q33698930
Right ventricular dysfunction following acute myocardial infarction in the absence of pulmonary hypertension in the mouseQ33859417
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Pharmacological induction of transforming growth factor-beta1 in rat models enhances radiation injury in the intestine and the heartQ34922963
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Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivityQ35591349
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A Preliminary Study on Racial Differences in HMOX1, NFE2L2, and TGFβ1 Gene Polymorphisms and Radiation-Induced Late Normal Tissue Toxicity.Q36074303
Cancer-related fatigue--mechanisms, risk factors, and treatmentsQ36332266
Targeting the TGFβ signalling pathway in diseaseQ36462348
Progressive pulmonary fibrosis is mediated by TGF-beta isoform 1 but not TGF-beta3Q36597016
A mouse model of radiation-induced cardiomyopathy.Q36985606
Radiation-related heart disease: current knowledge and future prospectsQ37542024
Transforming growth factor (TGF)-β signaling in cardiac remodeling.Q37808014
The role of TGF-β in bone metastasis: novel therapeutic perspectivesQ38129383
Semi-mechanistic modelling of the tumour growth inhibitory effects of LY2157299, a new type I receptor TGF-beta kinase antagonist, in miceQ40044519
Prevention of radiation-induced pneumonitis by recombinant adenovirus-mediated transferring of soluble TGF-beta type II receptor geneQ40277998
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Irradiation induces a biphasic expression of pro-inflammatory cytokines in the lung.Q42464320
Dose-dependent induction of transforming growth factor beta (TGF-beta) in the lung tissue of fibrosis-prone mice after thoracic irradiationQ42489472
Assessment of the protective effect of amifostine on radiation-induced pulmonary toxicity.Q44191372
Latent TGFbeta1 activation in the lung irradiated in vivoQ44300497
Radiation pneumonitis successfully treated with inhaled corticosteroidsQ44544730
Effects of lecithinized superoxide dismutase and/or pirfenidone against bleomycin-induced pulmonary fibrosis.Q44854084
Small molecular inhibitor of transforming growth factor-beta protects against development of radiation-induced lung injury.Q44937602
P433issue5
P304page(s)478-488
P577publication date2016-11-01
P1433published inRadiation ResearchQ2446628
P1476titleIPW-5371 Proves Effective as a Radiation Countermeasure by Mitigating Radiation-Induced Late Effects
P478volume186

Reverse relations

cites work (P2860)
Q89132824Intercellular communications-redox interactions in radiation toxicity; potential targets for radiation mitigation
Q88899477Mechanisms of Normal Tissue Injury From Irradiation
Q92859097New therapeutic insights into radiation-induced myocardial fibrosis
Q90581263Radiation-induced heart disease: a review of classification, mechanism and prevention
Q64986292The Role of Nrf2 in the Response to Normal Tissue Radiation Injury.
Q90238296The conditioned medium of human mesenchymal stromal cells reduces irradiation-induced damage in cardiac fibroblast cells