The angiogenic inhibitor long pentraxin PTX3 forms an asymmetric octamer with two binding sites for FGF2

scientific journal article

The angiogenic inhibitor long pentraxin PTX3 forms an asymmetric octamer with two binding sites for FGF2 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M109.085639
P3181OpenCitations bibliographic resource ID3634297
P932PMC publication ID2878532
P698PubMed publication ID20363749

P50authorAlberto MantovaniQ22069468
Barbara BottazziQ42306567
Anthony J DayQ46788972
Karl E KadlerQ47164163
Clair BaldockQ61014577
P2093author name stringDavid C Briggs
Antonio Verdoliva
Marcella Marcellini
Ragnar Lindstedt
David F Holmes
Vincenzo Rivieccio
Antonio Inforzato
Thomas A Jowitt
Giovanni Salvatori
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Synergy between ficolin-2 and pentraxin 3 boosts innate immune recognition and complement depositionQ28115835
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Binding of the long pentraxin PTX3 to factor H: interacting domains and function in the regulation of complement activationQ29147380
Coiled coils: a highly versatile protein folding motifQ29616419
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Structures and functions of mammalian collectins.Q31974713
Structure and function of the long pentraxin PTX3 glycosidic moiety: fine-tuning of the interaction with C1q and complement activation.Q33257880
PTX3 in small-vessel vasculitides: an independent indicator of disease activity produced at sites of inflammationQ34106947
Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune responseQ34159058
Biochemical and functional characterization of the interaction between pentraxin 3 and C1q.Q34184675
Determining the structure of biological macromolecules by transmission electron microscopy, single particle analysis and 3D reconstructionQ34263843
PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilizationQ34302929
TSG-14, a tumor necrosis factor- and IL-1-inducible protein, is a novel member of the pentaxin family of acute phase proteinsQ34305784
Prognostic significance of the long pentraxin PTX3 in acute myocardial infarctionQ34357988
Cloning of mouse ptx3, a new member of the pentraxin gene family expressed at extrahepatic sitesQ34380249
Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertilityQ34403569
Multimer formation and ligand recognition by the long pentraxin PTX3. Similarities and differences with the short pentraxins C-reactive protein and serum amyloid P component.Q34450228
Coiled coils at the edge of configurational heterogeneity. Structural analyses of parallel and antiparallel homotetrameric coiled coils reveal configurational sensitivity to a single solvent-exposed amino acid substitutionQ35607513
Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesisQ36111400
The long pentraxin PTX3 as a link among innate immunity, inflammation, and female fertilityQ36396595
The long pentraxin PTX3 in vascular pathologyQ36615475
Role of the soluble pattern recognition receptor PTX3 in vascular biologyQ36924394
Fibroblast growth factor 2-antagonist activity of a long-pentraxin 3-derived anti-angiogenic pentapeptideQ37294970
The long pentraxin PTX3 as a prototypic humoral pattern recognition receptor: interplay with cellular innate immunityQ37361426
Anti-Aspergillus fumigatus efficacy of pentraxin 3 alone and in combination with antifungalsQ37598729
Selective recognition of fibroblast growth factor-2 by the long pentraxin PTX3 inhibits angiogenesisQ40576794
Size-exclusion chromatography with on-line light-scattering, absorbance, and refractive index detectors for studying proteins and their interactions.Q41115325
Long pentraxins: an emerging group of proteins with diverse functionsQ41194582
Investigating interactions of the pentraxins serum amyloid P component and C-reactive protein by mass spectrometryQ41877441
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Pentraxin 3 inhibits fibroblast growth factor 2-dependent activation of smooth muscle cells in vitro and neointima formation in vivoQ43905775
Structural characterization of PTX3 disulfide bond network and its multimeric status in cumulus matrix organizationQ46788898
PTX3 interacts with inter-alpha-trypsin inhibitor: implications for hyaluronan organization and cumulus oophorus expansionQ48786237
Knockout of pentraxin 3, a downstream target of growth differentiation factor-9, causes female subfertilityQ48859172
Identification of an antiangiogenic FGF2-binding site in the N terminus of the soluble pattern recognition receptor PTX3.Q51585406
High-level expression and efficient purification of recombinant human long pentraxin PTX3 in Chinese hamster ovary cells.Q51804571
Complexity and complementarity of outer membrane protein A recognition by cellular and humoral innate immunity receptors.Q51817209
Pentraxin 3, a new marker for vascular inflammation, predicts adverse clinical outcomes in patients with heart failure.Q53510759
Complement Dependent Amplification of the Innate Response to a Cognate Microbial Ligand by the Long Pentraxin PTX3Q59510820
P433issue23
P407language of work or nameEnglishQ1860
P921main subjectidentical protein bindingQ14762994
Pentraxin 3Q21120502
cell biologyQ7141
P304page(s)17681-17692
P577publication date2010-04-02
P1433published inJournal of Biological ChemistryQ867727
P1476titleThe angiogenic inhibitor long pentraxin PTX3 forms an asymmetric octamer with two binding sites for FGF2
P478volume285

Reverse relations

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