Pentraxins in the activation and regulation of innate immunity

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Pentraxins in the activation and regulation of innate immunity is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1111/IMR.12476
P932PMC publication ID5412954
P698PubMed publication ID27782337

P50authorAlberto MantovaniQ22069468
Barbara BottazziQ42306567
Seppo MeriQ42702450
Kenji DaigoQ42842871
Cecilia GarlandaQ60001307
Antonio InforzatoQ92379091
Isabella BarajonQ114780574
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Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instabilityQ22242922
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A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degenerationQ24523983
Complement factor H polymorphism in age-related macular degenerationQ24553334
Structural basis for engagement by complement factor H of C3b on a self surfaceQ24604385
Dual interaction of factor H with C3d and glycosaminoglycans in host-nonhost discrimination by complementQ24619612
C-reactive protein: a critical updateQ24672855
Neutralizing tumor-promoting chronic inflammation: a magic bullet?Q26830931
C-reactive protein and coronary heart disease: a critical reviewQ37281648
Neutrophil-derived azurocidin alarms the immune systemQ37310038
Humoral pattern recognition molecules: mannan-binding lectin and ficolins.Q37607216
The acute-phase protein PTX3 is an essential mediator of glial scar formation and resolution of brain edema after ischemic injuryQ37627769
Elevated Pentraxin 3 in bone metastatic breast cancer is correlated with osteolytic functionQ37660315
The long pentraxin PTX3: a modulator of the immunoinflammatory response in atherosclerosis and cardiovascular diseases.Q37775325
Complement deficiency states and associated infectionsQ37882132
Interactions of the humoral pattern recognition molecule PTX3 with the complement systemQ38042225
PTX3 as a paradigm for the interaction of pentraxins with the complement systemQ38112903
Prognostic and diagnostic potential of local and circulating levels of pentraxin 3 in lung cancer patientsQ38386941
Pentraxins and Collectins: Friend or Foe during Pathogen Invasion?Q38611424
Recombinant human pentraxin-2 therapy in patients with idiopathic pulmonary fibrosis: safety, pharmacokinetics and exploratory efficacy.Q38909103
The humoral pattern recognition molecule PTX3 is a key component of innate immunity against urinary tract infectionQ39003052
A single amino acid substitution in the hemagglutinin of H3N2 subtype influenza A viruses is associated with resistance to the long pentraxin PTX3 and enhanced virulence in miceQ39048437
Recombinant human serum amyloid P in healthy volunteers and patients with pulmonary fibrosisQ39472918
iC3b-opsonized apoptotic cells mediate a distinct anti-inflammatory response and transcriptional NF-kappaB-dependent blockadeQ39758134
The alternative pathway of complementQ40118346
The factor H variant associated with age-related macular degeneration (His-384) and the non-disease-associated form bind differentially to C-reactive protein, fibromodulin, DNA, and necrotic cellsQ40172276
Regulation of complement activation by C-reactive protein: targeting of the inhibitory activity of C4b-binding proteinQ40271737
Genetic variation in PTX3 and plasma levels associated with hepatocellular carcinoma in patients with HCV.Q40509021
Membrane proteins that protect against complement lysisQ40737575
Collectins: collagenous C-type lectins of the innate immune defense systemQ40738902
The immunoproteasome controls the availability of the cardioprotective pattern recognition molecule Pentraxin3.Q40906092
Long pentraxins: an emerging group of proteins with diverse functionsQ41194582
PTX3 Polymorphisms and Invasive Mold Infections After Solid Organ TransplantQ41228764
Pentraxin 3 Induces Vascular Endothelial Dysfunction Through a P-selectin/Matrix Metalloproteinase-1 PathwayQ41276392
Serum amyloid P-component is an acute-phase reactant in the mouseQ41461262
Elevations of inflammatory markers PTX3 and sST2 after resuscitation from cardiac arrest are associated with multiple organ dysfunction syndrome and early deathQ41726511
Protective effect of the long pentraxin PTX3 against histone-mediated endothelial cell cytotoxicity in sepsisQ41737016
Complement factor H binds at two independent sites to C-reactive protein in acute phase concentrationsQ42021566
Genetic PTX3 deficiency and aspergillosis in stem-cell transplantationQ42230664
Heterocomplexes of mannose-binding lectin and the pentraxins PTX3 or serum amyloid P component trigger cross-activation of the complement systemQ42584975
THE OCCURRENCE DURING ACUTE INFECTIONS OF A PROTEIN NOT NORMALLY PRESENT IN THE BLOOD : III. IMMUNOLOGICAL PROPERTIES OF THE C-REACTIVE PROTEIN AND ITS DIFFERENTIATION FROM NORMAL BLOOD PROTEINS.Q42812402
Persisting high levels of plasma pentraxin 3 over the first days after severe sepsis and septic shock onset are associated with mortality.Q43179135
Pentraxin 3 inhibits acute renal injury-induced interstitial fibrosis through suppression of IL-6/Stat3 pathwayQ43478901
Dynamic induction of the long pentraxin PTX3 in the CNS after limbic seizures: evidence for a protective role in seizure-induced neurodegenerationQ43694176
Plasma pentraxin 3 in patients with chronic kidney disease: associations with renal function, protein-energy wasting, cardiovascular disease, and mortalityQ44571381
DC-SIGN (CD209), pentraxin 3 and vitamin D receptor gene variants associate with pulmonary tuberculosis risk in West Africans.Q46515698
The physiological structure of human C-reactive protein and its complex with phosphocholineQ27618638
C-reactive protein and SAP-like pentraxin are both present in Limulus polyphemus haemolymph: crystal structure of Limulus SAPQ27619297
Structural recognition and functional activation of FcγR by innate pentraxinsQ27652907
Cancer-related inflammationQ27860907
Neutrophil extracellular traps kill bacteriaQ27860996
Long-Pentraxin 3 Derivative as a Small-Molecule FGF Trap for Cancer TherapyQ28115288
Synergy between ficolin-2 and pentraxin 3 boosts innate immune recognition and complement depositionQ28115835
Long pentraxin 3/tumor necrosis factor-stimulated gene-6 interaction: a biological rheostat for fibroblast growth factor 2-mediated angiogenesisQ28118263
The angiogenic inhibitor long pentraxin PTX3 forms an asymmetric octamer with two binding sites for FGF2Q28118397
M-ficolin interacts with the long pentraxin PTX3: a novel case of cross-talk between soluble pattern-recognition moleculesQ28118843
Analysis of variants in the complement factor H, the elongation of very long chain fatty acids-like 4 and the hemicentin 1 genes of age-related macular degeneration in the Finnish populationQ28255592
Heparin-binding protein: an early marker of circulatory failure in sepsisQ28257216
Acute-phase proteins and other systemic responses to inflammationQ28296941
Myeloperoxidase: a front-line defender against phagocytosed microorganismsQ28393101
PTX3 function as an opsonin for the dectin-1-dependent internalization of zymosan by macrophagesQ28588062
Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant dataQ28742740
Binding of the long pentraxin PTX3 to factor H: interacting domains and function in the regulation of complement activationQ29147380
Role of pentraxin 3 in shaping arthritogenic alphaviral disease: from enhanced viral replication to immunomodulation.Q30371909
Pandemic H1N1 influenza A viruses are resistant to the antiviral activities of innate immune proteins of the collectin and pentraxin superfamiliesQ30393325
Transgenic human C-reactive protein is not proatherogenic in apolipoprotein E-deficient mice.Q30475959
Alveolar pentraxin 3 as an early marker of microbiologically confirmed pneumonia: a threshold-finding prospective observational studyQ30596839
Deciphering the fine details of c1 assembly and activation mechanisms: "mission impossible"?Q30596999
High plasma level of long pentraxin 3 (PTX3) is associated with fatal disease in bacteremic patients: a prospective cohort studyQ31004218
Elevated plasma levels of the long pentraxin, pentraxin 3, in severe dengue virus infectionsQ33217837
Structure and function of the long pentraxin PTX3 glycosidic moiety: fine-tuning of the interaction with C1q and complement activation.Q33257880
Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcomeQ33359495
Genetics and complement in atypical HUS.Q33389945
Histones induce rapid and profound thrombocytopenia in miceQ33395916
Tissue-specific host recognition by complement factor H is mediated by differential activities of its glycosaminoglycan-binding regionsQ33405609
Complement activation in diseases presenting with thrombotic microangiopathyQ33408231
Disturbed sialic acid recognition on endothelial cells and platelets in complement attack causes atypical hemolytic uremic syndromeQ33430961
Self-nonself discrimination by the complement systemQ33433754
Discrimination between activators and nonactivators of the alternative pathway of complement: regulation via a sialic acid/polyanion binding site on factor HQ33596128
Aberrant methylation of the 3q25 tumor suppressor gene PTX3 in human esophageal squamous cell carcinomaQ35526413
An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair modeQ35671242
PTX3 gene activation in EGF-induced head and neck cancer cell metastasisQ35781404
Pentraxin-3 as a marker of disease severity and risk of death in patients with necrotizing soft tissue infections: a nationwide, prospective, observational study.Q35924554
The proteomic profile of circulating pentraxin 3 (PTX3) complex in sepsis demonstrates the interaction with azurocidin 1 and other components of neutrophil extracellular trapsQ36209095
Neutrophil extracellular traps: double-edged swords of innate immunityQ36226113
The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular trapsQ36229261
Pentraxins and Fc receptorsQ36317664
Implication of the oligomeric state of the N-terminal PTX3 domain in cumulus matrix assemblyQ36426931
The "sweet" side of a long pentraxin: how glycosylation affects PTX3 functions in innate immunity and inflammationQ36516810
Association between levels of pentraxin 3 and incidence of chronic kidney disease in the elderlyQ36533057
Inflammation and colorectal cancer: colitis-associated neoplasiaQ36597803
Influence of pH on wound-healing: a new perspective for wound-therapy?Q36647844
Novel links between the long pentraxin 3, endothelial dysfunction, and albuminuria in early and advanced chronic kidney diseaseQ36736700
Y402H polymorphism of complement factor H affects binding affinity to C-reactive proteinQ36860930
Role of the soluble pattern recognition receptor PTX3 in vascular biologyQ36924394
Decoys and Regulatory "Receptors" of the IL-1/Toll-Like Receptor SuperfamilyQ36994635
Clinical impact of pentraxin family expression on prognosis of pancreatic carcinomaQ37081859
Associations of pentraxin 3 with cardiovascular disease and all-cause death: the Cardiovascular Health StudyQ37141153
The long pentraxin PTX3 is crucial for tissue inflammation after intestinal ischemia and reperfusion in miceQ37164532
The pentraxins PTX3 and SAP in innate immunity, regulation of inflammation and tissue remodellingQ33632041
PTX3, a humoral pattern recognition molecule at the interface between microbe and matrix recognitionQ33632044
Associations of pentraxin 3 with cardiovascular disease: the Multi-Ethnic Study of AtherosclerosisQ33748025
Regulation of complement activation by C-reactive protein: targeting the complement inhibitory activity of factor H by an interaction with short consensus repeat domains 7 and 8-11.Q33874500
PTX3, A prototypical long pentraxin, is an early indicator of acute myocardial infarction in humansQ33912738
Lack of the long pentraxin PTX3 promotes autoimmune lung disease but not glomerulonephritis in murine systemic lupus erythematosusQ33920964
Targeting C-reactive protein for the treatment of cardiovascular disease.Q33995386
Human pentraxin 3 binds to the complement regulator c4b-binding protein.Q34018825
Extracellular histones are major mediators of death in sepsisQ34019901
An integrated view of humoral innate immunity: pentraxins as a paradigmQ34020449
Circulating levels of the long pentraxin PTX3 correlate with severity of infection in critically ill patientsQ34083517
Antitumor and anti-inflammatory effects of trabectedin on human myxoid liposarcoma cells.Q34102992
Associations of pentraxin-3 with cardiovascular events, incident heart failure, and mortality among persons with coronary heart disease: data from the Heart and Soul StudyQ34150807
Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune responseQ34159058
Biochemical and functional characterization of the interaction between pentraxin 3 and C1q.Q34184675
Mannose binding lectin is required for alphavirus-induced arthritis/myositisQ34211498
Prognostic significance of the long pentraxin PTX3 in acute myocardial infarctionQ34357988
Cloning of mouse ptx3, a new member of the pentraxin gene family expressed at extrahepatic sitesQ34380249
IFN-gamma-inducible protein 10 and pentraxin 3 plasma levels are tools for monitoring inflammation and disease activity in Mycobacterium tuberculosis infectionQ34395156
Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertilityQ34403569
PTX3 genetic variations affect the risk of Pseudomonas aeruginosa airway colonization in cystic fibrosis patientsQ34406338
Incorporation of pentraxin 3 into hyaluronan matrices is tightly regulated and promotes matrix cross-linkingQ34430984
Multimer formation and ligand recognition by the long pentraxin PTX3. Similarities and differences with the short pentraxins C-reactive protein and serum amyloid P component.Q34450228
PTX3 is an extrinsic oncosuppressor regulating complement-dependent inflammation in cancerQ34462648
Influence of pentraxin 3 (PTX3) genetic variants on myocardial infarction risk and PTX3 plasma levelsQ34534979
Pentraxin 3 (PTX3) is associated with severe sepsis and fatal disease in emergency room patients with suspected infection: a prospective cohort studyQ34558563
Microbes bind complement inhibitor factor H via a common siteQ34699715
Complement and systemic lupus erythematosusQ34731255
Pentraxin-3 serum levels are associated with disease severity and mortality in patients with systemic inflammatory response syndromeQ34988829
Incremental prognostic significance of the elevated levels of pentraxin 3 in patients with heart failure with normal left ventricular ejection fractionQ35026270
Recognition and clearance of apoptotic cells: a role for complement and pentraxinsQ35077167
Recognition of Neisseria meningitidis by the long pentraxin PTX3 and its role as an endogenous adjuvantQ35191828
Three-month variation of plasma pentraxin 3 compared with C-reactive protein, albumin and homocysteine levels in haemodialysis patientsQ35227705
Differential expression of pentraxin 3 in neutrophilsQ35467092
Antiviral activity of the long chain pentraxin PTX3 against influenza virusesQ46739811
Structural characterization of PTX3 disulfide bond network and its multimeric status in cumulus matrix organizationQ46788898
Long pentraxin PTX3 is associated with mortality and disease severity in severe LeptospirosisQ47798697
Pentraxin-3 in chronic heart failure: the CORONA and GISSI-HF trialsQ48458509
Inhibition of pentraxin 3 in glioma cells impairs proliferation and invasion in vitro and in vivoQ48687445
PTX3 interacts with inter-alpha-trypsin inhibitor: implications for hyaluronan organization and cumulus oophorus expansionQ48786237
Streptococcus pneumoniae evades complement attack and opsonophagocytosis by expressing the pspC locus-encoded Hic protein that binds to short consensus repeats 8-11 of factor H.Q51728887
Regulation of leukocyte recruitment by the long pentraxin PTX3.Q51774594
Complexity and complementarity of outer membrane protein A recognition by cellular and humoral innate immunity receptors.Q51817209
Effect of chronic ethanol consumption on the expression of complement components and acute-phase proteins in liver.Q51902264
Pentraxin-3 Silencing Suppresses Gastric Cancer-related Inflammation by Inhibiting Chemotactic Migration of Macrophages.Q53218177
The long pentraxin PTX-3 in prevalent hemodialysis patients: associations with comorbidities and mortality.Q53496784
Pentraxin 3, a new marker for vascular inflammation, predicts adverse clinical outcomes in patients with heart failure.Q53510759
Pentraxin 3 accelerates lung injury in high tidal volume ventilation in mice.Q54318838
Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunityQ56595317
PTX3 Binds MD-2 and Promotes TRIF-Dependent Immune Protection in AspergillosisQ56942190
Endogenous and exogenous pentraxin-3 limits postischemic acute and chronic kidney injuryQ56942220
The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosaQ56942421
Role of complement and Fc receptors in the protective activity of the long pentraxin PTX3 against Aspergillus fumigatusQ56942510
Deficiency of the Long Pentraxin PTX3 Promotes Vascular Inflammation and AtherosclerosisQ56942567
PENTRAXIN 3 AND C-REACTIVE PROTEIN IN SEVERE MENINGOCOCCAL DISEASEQ56942619
Cardioprotective Function of the Long Pentraxin PTX3 in Acute Myocardial InfarctionQ56942653
PTX3 as a Potential Novel Tool for the Diagnosis and Monitoring of Pulmonary Fungal Infections in Immuno-compromised Pediatric PatientsQ56942714
Dual function of the long pentraxin PTX3 in resistance against pulmonary infection with Klebsiella pneumoniae in transgenic miceQ56942821
Pentraxin 3 protects from MCMV infection and reactivation through TLR sensing pathways leading to IRF3 activationQ56942879
Pentraxin-3 Is a Novel Biomarker of Lung CarcinomaQ57941010
Complement Dependent Amplification of the Innate Response to a Cognate Microbial Ligand by the Long Pentraxin PTX3Q59510820
Plasma and Tissue Expression of the Long Pentraxin 3 During Normal Pregnancy and PreeclampsiaQ60609634
Primary structure of human C-reactive proteinQ67469036
Independent association of serum amyloid P component, protein S, and complement C4b with complement C4b-binding protein and subsequent association of the complex with membranesQ68434491
Binding and complement activation by C-reactive protein via the collagen-like region of C1q and inhibition of these reactions by monoclonal antibodies to C-reactive protein and C1qQ70120011
Evidence for the binding of human serum amyloid P component to Clq and Fab gammaQ70317183
Serum ?2-microglobulin, sialic acid, and C-reactive protein in systemic lupus erythematosusQ72696406
C-reactive protein inhibits pneumococcal activation of the alternative pathway by increasing the interaction between factor H and C3bQ72818234
Each of the three binding sites on complement factor H interacts with a distinct site on C3bQ73850099
Complement C3b/C3d and cell surface polyanions are recognized by overlapping binding sites on the most carboxyl-terminal domain of complement factor HQ78625995
Pentraxin 3 is a new inflammatory marker correlated with left ventricular diastolic dysfunction and heart failure with normal ejection fractionQ83395035
Long pentraxin 3 (PTX3) expression and release by neutrophils in vitro and in ulcerative colitisQ83892738
Pentraxin 3, a sensitive early marker of hemodialysis-induced inflammationQ85647931
Pentraxin 3: a novel biomarker for predicting progression from prostatic inflammation to prostate cancerQ88123573
P433issue1
P304page(s)202-217
P577publication date2016-11-01
P1433published inImmunological ReviewsQ15724582
P1476titlePentraxins in the activation and regulation of innate immunity
P478volume274

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cites work (P2860)
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