| scholarly article | Q13442814 |
| P2093 | author name string | Erika L. F. Holzbaur | |
| Yvette C. Wong | |||
| P2860 | cites work | PINK1 is selectively stabilized on impaired mitochondria to activate Parkin | Q21145802 |
| PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1 | Q24297155 | ||
| Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis | Q24300284 | ||
| Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy | Q24300975 | ||
| p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both | Q24301629 | ||
| Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth | Q24304447 | ||
| Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism | Q24309753 | ||
| p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy | Q24312147 | ||
| A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation | Q24315723 | ||
| A role for NBR1 in autophagosomal degradation of ubiquitinated substrates | Q24316135 | ||
| Parkin is recruited selectively to impaired mitochondria and promotes their autophagy | Q24317471 | ||
| Hereditary early-onset Parkinson's disease caused by mutations in PINK1 | Q24337084 | ||
| Optineurin negatively regulates TNFalpha- induced NF-kappaB activation by competing with NEMO for ubiquitinated RIP | Q24337587 | ||
| LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing | Q24597817 | ||
| Mechanisms of mitophagy | Q27310261 | ||
| Adult-onset primary open-angle glaucoma caused by mutations in optineurin | Q28217964 | ||
| Huntingtin interacts with a family of WW domain proteins | Q28279245 | ||
| The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation | Q28591685 | ||
| Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum | Q29614500 | ||
| Mutations of optineurin in amyotrophic lateral sclerosis | Q29614836 | ||
| The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria | Q29615619 | ||
| Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization | Q29615622 | ||
| Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin | Q29615623 | ||
| Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin | Q29615625 | ||
| PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy | Q29616005 | ||
| PINK1-dependent recruitment of Parkin to mitochondria in mitophagy | Q29620567 | ||
| Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons | Q30425491 | ||
| Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome | Q30525665 | ||
| VCP is essential for mitochondrial quality control by PINK1/Parkin and this function is impaired by VCP mutations | Q30540665 | ||
| The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway | Q33552320 | ||
| Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming | Q34107322 | ||
| p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria | Q34269257 | ||
| Organization and dynamics of human mitochondrial DNA. | Q34320137 | ||
| Bit-by-bit autophagic removal of parkin-labelled mitochondria | Q34369366 | ||
| Genome-wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget's disease of bone | Q35552797 | ||
| Cellular and molecular biology of optineurin | Q36905164 | ||
| Mitochondria removal by autophagy | Q37831014 | ||
| Mitochondria and ALS: implications from novel genes and pathways. | Q38019306 | ||
| Maintenance of retinal ganglion cell mitochondrial functions as a neuroprotective strategy in glaucoma. | Q38045590 | ||
| Mitochondrial dynamics in neurodegeneration | Q38060435 | ||
| The LC3 interactome at a glance | Q38171884 | ||
| Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates | Q40710483 | ||
| Alterations in the common fragile site gene Parkin in ovarian and other cancers | Q44653680 | ||
| Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age. | Q48199015 | ||
| Chromophore-assisted light inactivation (CALI) using the phototoxic fluorescent protein KillerRed. | Q50690849 | ||
| Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin. | Q51387140 | ||
| Structures containing Atg9A and the ULK1 complex independently target depolarized mitochondria at initial stages of Parkin-mediated mitophagy. | Q54534151 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 42 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | mitochondrion | Q39572 |
| amyotrophic lateral sclerosis | Q206901 | ||
| Optineurin | Q7098997 | ||
| autophagy | Q288322 | ||
| parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization | Q22282659 | ||
| P304 | page(s) | E4439–4448 | |
| P577 | publication date | 2014-10-21 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation | |
| P478 | volume | 111 |
| Q28548061 | A Glaucoma-Associated Variant of Optineurin, M98K, Activates Tbk1 to Enhance Autophagosome Formation and Retinal Cell Death Dependent on Ser177 Phosphorylation of Optineurin |
| Q38720656 | A STRIPAK complex mediates axonal transport of autophagosomes and dense core vesicles through PP2A regulation |
| Q56532448 | A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy |
| Q38882232 | A critical role of Hrd1 in the regulation of optineurin degradation and aggresome formation |
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| Q55286697 | A novel CHCHD10 mutation implicates a Mia40-dependent mitochondrial import deficit in ALS. |
| Q29347553 | A novel amyotrophic lateral sclerosis mutation in OPTN induces ER stress and Golgi fragmentation in vitro. |
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| Q41525479 | Autophagy Dysregulation in ALS: When Protein Aggregates Get Out of Hand |
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| Q38743703 | Autophagy and Obesity-Related Lung Disease |
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| Q89623380 | Blockage of Autophagic Flux and Induction of Mitochondria Fragmentation by Paroxetine Hydrochloride in Lung Cancer Cells Promotes Apoptosis via the ROS-MAPK Pathway |
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| Q54987116 | ER-mitochondria signaling in Parkinson's disease. |
| Q47140884 | Effects of exercise on obesity-induced mitochondrial dysfunction in skeletal muscle |
| Q61799073 | Emerging Concepts and Functions of Autophagy as a Regulator of Synaptic Components and Plasticity |
| Q64078574 | Emerging Role of the Nucleolar Stress Response in Autophagy |
| Q27009194 | Emerging strategies to effectively target autophagy in cancer |
| Q92876450 | Emerging views of mitophagy in immunity and autoimmune diseases |
| Q90424438 | Evolving and Expanding the Roles of Mitophagy as a Homeostatic and Pathogenic Process |
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| Q39267828 | Expanding perspectives on the significance of mitophagy in cancer. |
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| Q90127184 | Impairment of Lysosome Function and Autophagy in Rare Neurodegenerative Diseases |
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| Q90072341 | Inter-Organelle Membrane Contact Sites and Mitochondrial Quality Control during Aging: A Geroscience View |
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| Q38638036 | Lost in translation: miRNAs and mRNAs in ischemic preconditioning and ischemia/reperfusion injury |
| Q39303267 | Major review: Molecular genetics of primary open-angle glaucoma |
| Q91650616 | Mammalian Mitophagosome Formation: A Focus on the Early Signals and Steps |
| Q35819272 | Measurement of Systemic Mitochondrial Function in Advanced Primary Open-Angle Glaucoma and Leber Hereditary Optic Neuropathy |
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| Q36840116 | Mechanisms of Selective Autophagy in Normal Physiology and Cancer |
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| Q49612593 | Mechanisms, pathophysiological roles and methods for analyzing mitophagy - recent insights. |
| Q38887102 | Mechanistic insights into selective autophagy pathways: lessons from yeast |
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| Q38336639 | Minireview: Autophagy in pancreatic β-cells and its implication in diabetes |
| Q37346842 | Miro phosphorylation sites regulate Parkin recruitment and mitochondrial motility |
| Q91982212 | Mitochondrial Transport and Turnover in the Pathogenesis of Amyotrophic Lateral Sclerosis |
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| Q47820990 | Mitochondrial fission facilitates the selective mitophagy of protein aggregates. |
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| Q38688806 | Mitochondrial quality control in the diabetic heart |
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| Q92129107 | Mitophagy in Parkinson's Disease: From Pathogenesis to Treatment |
| Q92481855 | Mitophagy in hepatocytes: Types, initiators and role in adaptive ethanol metabolism☆ |
| Q90398052 | Mitophagy in the Retinal Pigment Epithelium of Dry Age-Related Macular Degeneration Investigated in the NFE2L2/PGC-1α-/- Mouse Model |
| Q26776469 | Mitophagy programs: mechanisms and physiological implications of mitochondrial targeting by autophagy |
| Q97526682 | Mitophagy, Mitochondrial Homeostasis, and Cell Fate |
| Q91795612 | Mitophagy: An Emerging Role in Aging and Age-Associated Diseases |
| Q28383419 | Mitophagy: Basic Mechanism and Potential Role in Kidney Diseases |
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| Q46254743 | PINK1-PRKN/PARK2 pathway of mitophagy is activated to protect against Renal ischemia-reperfusion injury |
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| Q64068837 | STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism |
| Q59329245 | Selective Autophagy and Xenophagy in Infection and Disease |
| Q92230753 | Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform |
| Q53513139 | Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum. |
| Q28073077 | Sending Out an SOS: Mitochondria as a Signaling Hub |
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| Q91723371 | Somatic and germline mutations in the tumor suppressor gene PARK2 impair PINK1/Parkin-mediated mitophagy in lung cancer cells |
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| Q38875214 | TBK1 controls autophagosomal engulfment of polyubiquitinated mitochondria through p62/SQSTM1 phosphorylation |
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| Q91812568 | The Impact of Kinases in Amyotrophic Lateral Sclerosis at the Neuromuscular Synapse: Insights into BDNF/TrkB and PKC Signaling |
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| Q87629781 | The Role of Txnip in Mitophagy Dysregulation and Inflammasome Activation in Diabetic Retinopathy: A New Perspective |
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