| scholarly article | Q13442814 |
| P50 | author | Nektarios Tavernarakis | Q20986533 |
| Christina Ploumi | Q57562283 | ||
| P2093 | author name string | Athanasios Metaxakis | |
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| Autophagy: molecular machinery for self-eating | Q24678361 | ||
| Mitophagy plays a central role in mitochondrial ageing | Q26746323 | ||
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| Autophagy in stem cells | Q26823995 | ||
| Why should autophagic flux be assessed? | Q26851723 | ||
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| A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. | Q27860836 | ||
| A ubiquitin-like system mediates protein lipidation | Q27934137 | ||
| Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae | Q27935838 | ||
| Dual roles of Atg8-PE deconjugation by Atg4 in autophagy. | Q27937267 | ||
| Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation | Q27939934 | ||
| TFEB at a glance | Q28074375 | ||
| Huntingtin functions as a scaffold for selective macroautophagy | Q28118022 | ||
| VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD | Q28118851 | ||
| Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation | Q28118966 | ||
| The hallmarks of aging | Q28131641 | ||
| Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice | Q28131756 | ||
| Loss of autophagy in the central nervous system causes neurodegeneration in mice | Q28131804 | ||
| The hunt for huntingtin function: interaction partners tell many different stories | Q28203006 | ||
| Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease | Q28261987 | ||
| The roles of intracellular protein-degradation pathways in neurodegeneration | Q28269322 | ||
| Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases | Q28269333 | ||
| Epidemiology of Parkinson's disease | Q28271626 | ||
| Role of axonal transport in neurodegenerative diseases | Q28284096 | ||
| Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain | Q34733374 | ||
| Lithium delays progression of amyotrophic lateral sclerosis | Q34746211 | ||
| Induction of autophagy by a novel small molecule improves aβ pathology and ameliorates cognitive deficits | Q34764295 | ||
| Mitochondrial biogenesis and healthy aging | Q34802002 | ||
| Tau in Alzheimer disease and related tauopathies | Q34953869 | ||
| Age-induced reduction of autophagy-related gene expression is associated with onset of Alzheimer's disease | Q34987490 | ||
| Regulation of neuron mitochondrial biogenesis and relevance to brain health | Q34997535 | ||
| A small-molecule enhancer of autophagy decreases levels of Abeta and APP-CTF via Atg5-dependent autophagy pathway | Q35003193 | ||
| Spermidine induces autophagy by inhibiting the acetyltransferase EP300. | Q35079516 | ||
| Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer's disease | Q35174706 | ||
| Autophagosome-lysosome fusion is independent of V-ATPase-mediated acidification | Q35597410 | ||
| Regulation of autophagy by neuropathological protein TDP-43. | Q35639841 | ||
| Autophagic stress in neuronal injury and disease. | Q35828319 | ||
| Temporal dynamics of PARK2/parkin and OPTN/optineurin recruitment during the mitophagy of damaged mitochondria | Q35852837 | ||
| Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism | Q35853004 | ||
| Endosome function and dysfunction in Alzheimer's disease and other neurodegenerative diseases | Q36003508 | ||
| The altered autophagy mediated by TFEB in animal and cell models of amyotrophic lateral sclerosis | Q36225846 | ||
| Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43 | Q36236376 | ||
| Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease | Q36320351 | ||
| Lithium induces autophagy by inhibiting inositol monophosphatase | Q36321015 | ||
| TDP-43 loss of function increases TFEB activity and blocks autophagosome-lysosome fusion. | Q36478806 | ||
| Loss of Aβ43 Production Caused by Presenilin-1 Mutations in the Knockin Mouse Brain | Q36824224 | ||
| Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death | Q36858699 | ||
| Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan | Q36884177 | ||
| Yes-associated protein 1 and transcriptional coactivator with PDZ-binding motif activate the mammalian target of rapamycin complex 1 pathway by regulating amino acid transporters in hepatocellular carcinoma | Q36939981 | ||
| Nilotinib induces autophagy in hepatocellular carcinoma through AMPK activation | Q36947802 | ||
| Autophagy failure in Alzheimer's disease and the role of defective lysosomal acidification | Q36960882 | ||
| Dynein disruption perturbs post-synaptic components and contributes to impaired MuSK clustering at the NMJ: implication in ALS. | Q36990596 | ||
| Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease | Q37178375 | ||
| Age- and calorie restriction-related changes in rat brain mitochondrial DNA and TFAM binding. | Q37179899 | ||
| Defective recognition of LC3B by mutant SQSTM1/p62 implicates impairment of autophagy as a pathogenic mechanism in ALS-FTLD. | Q37189122 | ||
| Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies | Q37219529 | ||
| Mechanism of tau-induced neurodegeneration in Alzheimer disease and related tauopathies | Q37239077 | ||
| Combined lithium and valproate treatment delays disease onset, reduces neurological deficits and prolongs survival in an amyotrophic lateral sclerosis mouse model | Q37258301 | ||
| PINK1 is degraded through the N-end rule pathway | Q33638689 | ||
| Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster | Q33665807 | ||
| Huntington's disease: from molecular pathogenesis to clinical treatment | Q33773061 | ||
| Incidence of amyotrophic lateral sclerosis in Europe | Q33774202 | ||
| Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease | Q33832866 | ||
| Autophagy and the immune function in aging | Q33992522 | ||
| Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits | Q34043165 | ||
| Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease. | Q34069706 | ||
| PARK6 is a common cause of familial parkinsonism | Q34172948 | ||
| The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS. | Q34326849 | ||
| Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis | Q34373108 | ||
| Huntington disease: pathogenesis and treatment | Q34450055 | ||
| Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans | Q34472739 | ||
| Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome | Q34600785 | ||
| Does Huntingtin play a role in selective macroautophagy? | Q34618914 | ||
| PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria | Q34641661 | ||
| ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase. | Q34728044 | ||
| Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes | Q28302701 | ||
| AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 | Q28506431 | ||
| Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations | Q28506710 | ||
| Therapeutic Effect of Berberine on Huntington's Disease Transgenic Mouse Model | Q28546885 | ||
| Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies | Q28590387 | ||
| The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice | Q28591283 | ||
| Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice | Q28594828 | ||
| The cybrid model of sporadic Parkinson's disease | Q28751790 | ||
| Dynamic recruitment and activation of ALS-associated TBK1 with its target optineurin are required for efficient mitophagy | Q28829663 | ||
| Overexpression of Atg5 in mice activates autophagy and extends lifespan | Q29038178 | ||
| Autophagy: renovation of cells and tissues | Q29547206 | ||
| Autophagy and the integrated stress response | Q29547398 | ||
| Regulation mechanisms and signaling pathways of autophagy | Q29547416 | ||
| The role of Atg proteins in autophagosome formation | Q29547418 | ||
| Sirtuin activators mimic caloric restriction and delay ageing in metazoans | Q29547766 | ||
| Isolation and characterization of yeast mutants in the cytoplasm to vacuole protein targeting pathway | Q29614186 | ||
| Induction of autophagy by spermidine promotes longevity | Q29614498 | ||
| Autophagic cell death: the story of a misnomer | Q29614564 | ||
| TFEB links autophagy to lysosomal biogenesis | Q29614835 | ||
| Mutations of optineurin in amyotrophic lateral sclerosis | Q29614836 | ||
| Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL | Q29615624 | ||
| Autophagy and aging | Q29616002 | ||
| Potential function for the Huntingtin protein as a scaffold for selective autophagy | Q30301372 | ||
| A microarray-based genetic screen for yeast chronological aging factors | Q30436367 | ||
| Deletion of the huntingtin polyglutamine stretch enhances neuronal autophagy and longevity in mice. | Q30437121 | ||
| Amyloid-β and tau: the trigger and bullet in Alzheimer disease pathogenesis | Q30457367 | ||
| Cystatin C-cathepsin B axis regulates amyloid beta levels and associated neuronal deficits in an animal model of Alzheimer's disease | Q30490690 | ||
| On the use of in vivo cargo velocity as a biophysical marker | Q30495017 | ||
| Atg9 vesicles are an important membrane source during early steps of autophagosome formation | Q30523963 | ||
| mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies. | Q30539812 | ||
| Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease | Q30545790 | ||
| PGC-1α rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function. | Q30583566 | ||
| In vivo axonal transport deficits in a mouse model of fronto-temporal dementia | Q30831646 | ||
| WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy | Q30854841 | ||
| Protein aggregation and protein instability govern familial amyotrophic lateral sclerosis patient survival | Q33356197 | ||
| Sporadic and hereditary amyotrophic lateral sclerosis (ALS). | Q33359049 | ||
| Regulation of amyloid precursor protein processing by the Beclin 1 complex | Q33608732 | ||
| Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases | Q33613123 | ||
| SNARE-mediated membrane fusion in autophagy. | Q38898386 | ||
| Formation of hippocampal mHTT aggregates leads to impaired spatial memory, hippocampal activation and adult neurogenesis. | Q38912340 | ||
| Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activation | Q38978483 | ||
| Defects in trafficking bridge Parkinson's disease pathology and genetics | Q39004335 | ||
| Autophagy Receptors and Neurodegenerative Diseases | Q39124082 | ||
| Brain aging and neurodegeneration: from a mitochondrial point of view | Q39233558 | ||
| The Role of the Multifunctional BAG3 Protein in Cellular Protein Quality Control and in Disease | Q39416466 | ||
| Amyloid beta: structure, biology and structure-based therapeutic development | Q39437881 | ||
| C9ORF72 is a GDP/GTP exchange factor for Rab8 and Rab39 and regulates autophagy | Q39520699 | ||
| Pathogenic lysosomal depletion in Parkinson's disease | Q39655523 | ||
| The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy | Q39662062 | ||
| Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria. | Q39676476 | ||
| The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS). | Q39689378 | ||
| Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice | Q39812158 | ||
| HspB8 chaperone activity toward poly(Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy. | Q40050938 | ||
| Interaction between familial amyotrophic lateral sclerosis (ALS)-linked SOD1 mutants and the dynein complex | Q40150834 | ||
| A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease. | Q41513615 | ||
| Inhibition of autophagy induction delays neuronal cell loss caused by dysfunctional ESCRT-III in frontotemporal dementia | Q41909984 | ||
| A novel quantitative assay of mitophagy: Combining high content fluorescence microscopy and mitochondrial DNA load to quantify mitophagy and identify novel pharmacological tools against pathogenic heteroplasmic mtDNA. | Q41917170 | ||
| Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of lipid droplets. | Q41978043 | ||
| Novel targets for Huntington's disease in an mTOR-independent autophagy pathway | Q41978909 | ||
| Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism. | Q42066100 | ||
| Mechanism of phospho-ubiquitin-induced PARKIN activation | Q42356433 | ||
| Macroautophagy is impaired in old murine brain tissue as well as in senescent human fibroblasts. | Q42372625 | ||
| Amino acid deprivation promotes intestinal homeostasis through autophagy | Q42384901 | ||
| Autophagy and microtubules - new story, old players. | Q42437740 | ||
| Trehalose ameliorates dopaminergic and tau pathology in parkin deleted/tau overexpressing mice through autophagy activation | Q42472879 | ||
| Resveratrol induces autophagy through death-associated protein kinase 1 (DAPK1) in human dermal fibroblasts under normal culture conditions | Q42710527 | ||
| Nilotinib reverses loss of dopamine neurons and improves motor behavior via autophagic degradation of α-synuclein in Parkinson's disease models | Q42711308 | ||
| Mitochondria and PGC-1α in Aging and Age-Associated Diseases | Q42738266 | ||
| Regulation of TDP-43 aggregation by phosphorylation and p62/SQSTM1. | Q42818503 | ||
| Aβ secretion and plaque formation depend on autophagy | Q44061458 | ||
| Amyloid beta-protein toxicity and the pathogenesis of Alzheimer disease | Q37310651 | ||
| Autophagy and aging: keeping that old broom working | Q37321185 | ||
| Differential autophagy power in the spinal cord and muscle of transgenic ALS mice. | Q37342284 | ||
| AMPK regulates autophagy by phosphorylating BECN1 at threonine 388. | Q37371625 | ||
| Impaired retrograde transport of axonal autophagosomes contributes to autophagic stress in Alzheimer's disease neurons | Q37585792 | ||
| Presenilin-1 mutations and Alzheimer's disease | Q37612530 | ||
| The beta-secretase enzyme BACE in health and Alzheimer's disease: regulation, cell biology, function, and therapeutic potential | Q37614747 | ||
| IP3 accumulation and/or inositol depletion: two downstream lithium's effects that may mediate its behavioral and cellular changes. | Q37650454 | ||
| Regulation of mATG9 trafficking by Src- and ULK1-mediated phosphorylation in basal and starvation-induced autophagy | Q37683998 | ||
| Chaperone-mediated autophagy dysfunction in the pathogenesis of neurodegeneration | Q37774072 | ||
| Genetic analysis of pathways to Parkinson disease | Q37801078 | ||
| A longer and healthier life with TOR down-regulation: genetics and drugs | Q37856372 | ||
| Autophagy: for better or for worse | Q37930982 | ||
| Autophagy dysregulation in amyotrophic lateral sclerosis. | Q37965873 | ||
| Autophagy and ageing: insights from invertebrate model organisms | Q38013488 | ||
| The global prevalence of dementia: a systematic review and metaanalysis | Q38073027 | ||
| Protein aggregation in amyotrophic lateral sclerosis. | Q38106862 | ||
| Advances in the pharmacological treatment of Parkinson's disease: targeting neurotransmitter systems | Q38123275 | ||
| At the end of the autophagic road: an emerging understanding of lysosomal functions in autophagy. | Q38173908 | ||
| Dysfunctional autophagy in Alzheimer's disease: pathogenic roles and therapeutic implications | Q38194496 | ||
| Autophagy in Huntington disease and huntingtin in autophagy | Q38256703 | ||
| Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease | Q38345839 | ||
| Autophagic activity in neuronal cell death | Q38528547 | ||
| Autophagosome closure requires membrane scission | Q38607125 | ||
| Nilotinib-induced autophagic changes increase endogenous parkin level and ubiquitination, leading to amyloid clearance | Q38615100 | ||
| Amphisomes: out of the autophagosome shadow? | Q38677867 | ||
| Disruption of microtubule network by Alzheimer abnormally hyperphosphorylated tau. | Q38686402 | ||
| Orchestrating the network of molecular pathways affecting aging: Role of nonselective autophagy and mitophagy | Q38712939 | ||
| Mechanisms of Selective Autophagy | Q38733387 | ||
| PINK1/Parkin mitophagy and neurodegeneration-what do we really know in vivo? | Q38755998 | ||
| The Biology of Huntingtin. | Q38759081 | ||
| Therapeutic potential of autophagy-enhancing agents in Parkinson's disease. | Q38765856 | ||
| Familial Alzheimer's Disease Mutations in Presenilin Generate Amyloidogenic Aβ Peptide Seeds | Q38776399 | ||
| mTor mediates tau localization and secretion: Implication for Alzheimer's disease | Q38897377 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 5 | |
| P921 | main subject | autophagy | Q288322 |
| neurodegeneration | Q1755122 | ||
| P577 | publication date | 2018-05-05 | |
| P1433 | published in | Cells | Q27724621 |
| P1476 | title | Autophagy in Age-Associated Neurodegeneration. | |
| P478 | volume | 7 |
| Q91656850 | A Comprehensive Review of Autophagy and Its Various Roles in Infectious, Non-Infectious, and Lifestyle Diseases: Current Knowledge and Prospects for Disease Prevention, Novel Drug Design, and Therapy |
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| Q92150931 | Circular RNA NF1-419 enhances autophagy to ameliorate senile dementia by binding Dynamin-1 and Adaptor protein 2 B1 in AD-like mice |
| Q92021892 | Could autophagy dysregulation link neurotropic viruses to Alzheimer's disease? |
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