Could autophagy dysregulation link neurotropic viruses to Alzheimer's disease?

scientific article published on 01 September 2019

Could autophagy dysregulation link neurotropic viruses to Alzheimer's disease? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4103/1673-5374.253508
P932PMC publication ID6557098
P698PubMed publication ID31089040

P2093author name stringAlberto Faggioni
Mara Cirone
Maria Anele Romeo
P2860cites workBeta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACEQ22010705
Herpes simplex virus type 1 DNA is located within Alzheimer's disease amyloid plaquesQ22252858
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Herpes simplex virus type 1 in brain and risk of Alzheimer's diseaseQ28302548
Autophagic flux without a block differentiates varicella-zoster virus infection from herpes simplex virus infectionQ30615036
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Variant-specific tropism of human herpesvirus 6 in human astrocytesQ33908734
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Herpes simplex virus 1 tropism for human sensory ganglion neurons in the severe combined immunodeficiency mouse model of neuropathogenesisQ36607105
The activation of KSHV lytic cycle blocks autophagy in PEL cellsQ36777265
Degradation of tau protein by autophagy and proteasomal pathwaysQ38027933
Circulating microRNAs as Biomarkers of Alzheimer's Disease: A Systematic ReviewQ38612037
Autophagy-mediated Regulation of BACE1 Protein Trafficking and Degradation.Q38777412
Herpes Simplex Virus-1 Encephalitis in Adults: Pathophysiology, Diagnosis, and ManagementQ38815369
Epstein-barr virus blocks the autophagic flux and appropriates the autophagic machinery to enhance viral replicationQ38964209
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APP and APLP1 are degraded through autophagy in response to proteasome inhibition in neuronal cells.Q39533342
Alzheimer's disease-specific tau phosphorylation is induced by herpes simplex virus type 1.Q39883251
HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy proteinQ40051258
beta-Amyloid precursor protein metabolites and loss of neuronal Ca2+ homeostasis in Alzheimer's disease.Q40384274
KSHV reduces autophagy in THP-1 cells and in differentiating monocytes by decreasing CAST/calpastatin and ATG5 expressionQ40509197
APP metabolism regulates tau proteostasis in human cerebral cortex neuronsQ40660550
Mitophagy plays an essential role in reducing mitochondrial production of reactive oxygen species and mutation of mitochondrial DNA by maintaining mitochondrial quantity and quality in yeastQ40810283
Aβ secretion and plaque formation depend on autophagyQ44061458
Infection with an endemic human herpesvirus disrupts critical glial precursor cell properties.Q44610816
Neuronal cytoskeletal dynamic modification and neurodegeneration induced by infection with herpes simplex virus type 1.Q45394000
Herpes simplex virus type 1 DNA is present in specific regions of brain from aged people with and without senile dementia of the Alzheimer typeQ45877119
Identification of Herpes Zoster-Associated Temporal Arteritis Among Cases of Giant Cell ArteritisQ47182000
The role of astrocytes in amyloid production and Alzheimer's diseaseQ47296419
Detection of active human herpesvirus-6 infection in the brain: correlation with polymerase chain reaction detection in cerebrospinal fluidQ48318086
Herpes simplex type 1 infects and establishes latency in the brain and trigeminal ganglia during primary infection of the lip in cotton rats and mice.Q48683086
Autophagy and Alzheimer's Disease: From Molecular Mechanisms to Therapeutic Implications.Q50023771
Modulation of the cytokine network in human adult astrocytes by human herpesvirus-6A.Q53675078
Contributions of neurotropic human herpesviruses herpes simplex virus 1 and human herpesvirus 6 to neurodegenerative disease pathology.Q54252789
Microglia in Alzheimer's Disease: Activated, Dysfunctional or Degenerative.Q55073016
Autophagy in Age-Associated Neurodegeneration.Q55405496
Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human HerpesvirusQ56004691
EBV reduces autophagy, intracellular ROS and mitochondria to impair monocyte survival and differentiationQ57455782
EBV and KSHV Infection Dysregulates Autophagy to Optimize Viral Replication, Prevent Immune Recognition and Promote TumorigenesisQ58588672
Active HHV-6 Infection of Cerebellar Purkinje Cells in Mood DisordersQ58729103
Impact of HHV-6A and HHV-6B lytic infection on autophagy and endoplasmic reticulum stressQ59351077
EBV up-regulates PD-L1 on the surface of primary monocytes by increasing ROS and activating TLR signaling and STAT3Q59356131
Alzheimer's Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain InfectionQ59357082
P433issue9
P921main subjectautophagyQ288322
P304page(s)1503-1506
P577publication date2019-09-01
P1433published inNeural Regeneration ResearchQ15710164
P1476titleCould autophagy dysregulation link neurotropic viruses to Alzheimer's disease?
P478volume14

Reverse relations

Q102149307The cross-talk between STAT1/STAT3 and ROS up-regulates PD-L1 and promotes the release of pro-inflammatory/immune suppressive cytokines in primary monocytes infected by HHV-6Bcites workP2860

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