Impaired retrograde transport of axonal autophagosomes contributes to autophagic stress in Alzheimer's disease neurons

scientific article published on 13 January 2017

Impaired retrograde transport of axonal autophagosomes contributes to autophagic stress in Alzheimer's disease neurons is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.7554/ELIFE.21776
P932PMC publication ID5235353
P698PubMed publication ID28085665

P50authorQian CaiQ89203734
P2093author name stringDaniyal Aikal
Prasad Tammineni
Tuancheng Feng
Xuan Ye
P2860cites workPersistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer diseaseQ21144713
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Axonal autophagosomes use the ride-on service for retrograde transport toward the somaQ36111774
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Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's diseaseQ37178375
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O-GlcNAc-modification of SNAP-29 regulates autophagosome maturationQ42152336
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Axonopathy and transport deficits early in the pathogenesis of Alzheimer's diseaseQ42474769
Impaired parkin-mediated mitochondrial targeting to autophagosomes differentially contributes to tissue pathology in lysosomal storage diseasesQ42564297
Rab5 and Rab7 control endocytic sorting along the axonal retrograde transport pathwayQ42600951
Age-dependent accumulation of soluble amyloid beta (Abeta) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-alpha (sAPP(alpha)) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK-3beta pathway in Alzheimer mQ42737591
Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spinesQ42913207
Amyloid-beta peptide oligomers disrupt axonal transport through an NMDA receptor-dependent mechanism that is mediated by glycogen synthase kinase 3beta in primary cultured hippocampal neurons.Q42976903
Glutamate and Amyloid β-Protein Rapidly Inhibit Fast Axonal Transport in Cultured Rat Hippocampal Neurons by Different MechanismsQ44605317
Axonal mitochondrial transport and potential are correlatedQ44901240
Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain.Q47798328
Alzheimer's disease-like dystrophic neurites characteristically associated with senile plaques are not found within other neurodegenerative diseases unless amyloid beta-protein deposition is presentQ48319297
Acute impairment of mitochondrial trafficking by beta-amyloid peptides in hippocampal neurons.Q48398341
The Vici Syndrome Protein EPG5 Is a Rab7 Effector that Determines the Fusion Specificity of Autophagosomes with Late Endosomes/Lysosomes.Q51536770
Characterization of transgene expression and Cre recombinase activity in a panel of Thy-1 promoter-Cre transgenic mice.Q52117446
Inflammatory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer's disease: age-dependent switch in the microglial phenotype from alternative to classic.Q53297957
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Multidisciplinary approaches for characterizing synaptic vesicle proteinsQ81130901
P4510describes a project that usesImageJQ1659584
P407language of work or nameEnglishQ1860
P921main subjectAlzheimer's diseaseQ11081
autophagyQ288322
autophagosomeQ14882441
P577publication date2017-01-13
P1433published ineLifeQ2000008
P1476titleImpaired retrograde transport of axonal autophagosomes contributes to autophagic stress in Alzheimer's disease neurons
P478volume6

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cites work (P2860)
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