scholarly article | Q13442814 |
P50 | author | Qian Cai | Q89203734 |
P2093 | author name string | Daniyal Aikal | |
Prasad Tammineni | |||
Tuancheng Feng | |||
Xuan Ye | |||
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Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP | Q28592685 | ||
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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis | Q29547501 | ||
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Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons | Q30425491 | ||
The cleavage products of amyloid-beta precursor protein are sorted to distinct carrier vesicles that are independently transported within neurites. | Q30487072 | ||
Long-distance axonal transport of AAV9 is driven by dynein and kinesin-2 and is trafficked in a highly motile Rab7-positive compartment | Q30573520 | ||
Autophagosome biogenesis in primary neurons follows an ordered and spatially regulated pathway | Q30584888 | ||
LC3 binding to the scaffolding protein JIP1 regulates processive dynein-driven transport of autophagosomes | Q30584890 | ||
Beta-amyloid causes depletion of synaptic vesicles leading to neurotransmission failure | Q33593939 | ||
Expression of A2V-mutated Aβ in Caenorhabditis elegans results in oligomer formation and toxicity | Q33797442 | ||
Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease | Q33814719 | ||
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Autophagy failure in Alzheimer's disease--locating the primary defect | Q34987827 | ||
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Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology | Q35747757 | ||
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Endolysosomal Deficits Augment Mitochondria Pathology in Spinal Motor Neurons of Asymptomatic fALS Mice. | Q35879849 | ||
Characterizing synaptic vesicle proteins using synaptosomal fractions and cultured hippocampal neurons | Q35939936 | ||
Lysosomal proteolysis inhibition selectively disrupts axonal transport of degradative organelles and causes an Alzheimer's-like axonal dystrophy | Q35955959 | ||
Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis. | Q35985387 | ||
Axonal autophagosomes use the ride-on service for retrograde transport toward the soma | Q36111774 | ||
Snapin recruits dynein to BDNF-TrkB signaling endosomes for retrograde axonal transport and is essential for dendrite growth of cortical neurons | Q36128601 | ||
Intraneuronal Abeta accumulation and origin of plaques in Alzheimer's disease | Q36196976 | ||
Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease | Q36320351 | ||
Docking of axonal mitochondria by syntaphilin controls their mobility and affects short-term facilitation | Q36484737 | ||
Further observations on hippocampal neurons in dispersed cell culture | Q36486488 | ||
The role of intracellular amyloid beta in Alzheimer's disease | Q36949148 | ||
Compartment-Specific Regulation of Autophagy in Primary Neurons | Q36952634 | ||
Autophagy, amyloidogenesis and Alzheimer disease | Q37011121 | ||
Kinesin-1-syntaphilin coupling mediates activity-dependent regulation of axonal mitochondrial transport | Q37034285 | ||
Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease | Q37178375 | ||
Early BDNF treatment ameliorates cell loss in the entorhinal cortex of APP transgenic mice | Q37196325 | ||
The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases | Q37336182 | ||
Mitochondrial trafficking and anchoring in neurons: New insight and implications | Q37677601 | ||
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Early and selective impairments in axonal transport kinetics of synaptic cargoes induced by soluble amyloid β-protein oligomers | Q41340280 | ||
Snapin-mediated BACE1 retrograde transport is essential for its degradation in lysosomes and regulation of APP processing in neurons | Q41896833 | ||
Role of endoplasmic reticulum, endosomal-lysosomal compartments, and microtubules in amyloid precursor protein metabolism of human neurons | Q41924248 | ||
GM1-ganglioside accumulation at the mitochondria-associated ER membranes links ER stress to Ca(2+)-dependent mitochondrial apoptosis | Q41970238 | ||
Primary lysosomal dysfunction causes cargo-specific deficits of axonal transport leading to Alzheimer-like neuritic dystrophy | Q42101162 | ||
O-GlcNAc-modification of SNAP-29 regulates autophagosome maturation | Q42152336 | ||
Amyloid-β Oligomers May Impair SNARE-Mediated Exocytosis by Direct Binding to Syntaxin 1a. | Q42409562 | ||
Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease | Q42474769 | ||
Impaired parkin-mediated mitochondrial targeting to autophagosomes differentially contributes to tissue pathology in lysosomal storage diseases | Q42564297 | ||
Rab5 and Rab7 control endocytic sorting along the axonal retrograde transport pathway | Q42600951 | ||
Age-dependent accumulation of soluble amyloid beta (Abeta) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-alpha (sAPP(alpha)) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK-3beta pathway in Alzheimer m | Q42737591 | ||
Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines | Q42913207 | ||
Amyloid-beta peptide oligomers disrupt axonal transport through an NMDA receptor-dependent mechanism that is mediated by glycogen synthase kinase 3beta in primary cultured hippocampal neurons. | Q42976903 | ||
Glutamate and Amyloid β-Protein Rapidly Inhibit Fast Axonal Transport in Cultured Rat Hippocampal Neurons by Different Mechanisms | Q44605317 | ||
Axonal mitochondrial transport and potential are correlated | Q44901240 | ||
Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain. | Q47798328 | ||
Alzheimer's disease-like dystrophic neurites characteristically associated with senile plaques are not found within other neurodegenerative diseases unless amyloid beta-protein deposition is present | Q48319297 | ||
Acute impairment of mitochondrial trafficking by beta-amyloid peptides in hippocampal neurons. | Q48398341 | ||
The Vici Syndrome Protein EPG5 Is a Rab7 Effector that Determines the Fusion Specificity of Autophagosomes with Late Endosomes/Lysosomes. | Q51536770 | ||
Characterization of transgene expression and Cre recombinase activity in a panel of Thy-1 promoter-Cre transgenic mice. | Q52117446 | ||
Inflammatory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer's disease: age-dependent switch in the microglial phenotype from alternative to classic. | Q53297957 | ||
Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study. | Q53369656 | ||
The mannose 6-phosphate receptor and the biogenesis of lysosomes | Q57960197 | ||
Multidisciplinary approaches for characterizing synaptic vesicle proteins | Q81130901 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Alzheimer's disease | Q11081 |
autophagy | Q288322 | ||
autophagosome | Q14882441 | ||
P577 | publication date | 2017-01-13 | |
P1433 | published in | eLife | Q2000008 |
P1476 | title | Impaired retrograde transport of axonal autophagosomes contributes to autophagic stress in Alzheimer's disease neurons | |
P478 | volume | 6 |
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Q55405496 | Autophagy in Age-Associated Neurodegeneration. |
Q38683916 | Autophagy-ERK1/2-Involved Disinhibition of Hippocampal Neurons Contributes to the Pre-Synaptic Toxicity Induced by Aβ42 Exposure |
Q52660576 | Axonal transport and maturation of lysosomes. |
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