| scholarly article | Q13442814 |
| P356 | DOI | 10.1038/TP.2016.217 |
| P2888 | exact match | https://scigraph.springernature.com/pub.10.1038/tp.2016.217 |
| P932 | PMC publication ID | 5315558 |
| P698 | PubMed publication ID | 27922641 |
| P50 | author | Lilah Toker | Q58208491 |
| Galila Agam | Q124000673 | ||
| P2093 | author name string | G T Berry | |
| D Moechars | |||
| H Einat | |||
| S Rapoport | |||
| Y Bersudsky | |||
| N Z Kara | |||
| Y Sade | |||
| P2860 | cites work | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Q22676705 |
| Regulation of autophagy by the inositol trisphosphate receptor | Q24294716 | ||
| Spatial expression patterns and biochemical properties distinguish a second myo-inositol monophosphatase IMPA2 from IMPA1 | Q24309650 | ||
| Definition of a metal-dependent/Li(+)-inhibited phosphomonoesterase protein family based upon a conserved three-dimensional core structure | Q24562986 | ||
| In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker | Q24633015 | ||
| A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding | Q25938984 | ||
| Lithium and autophagy | Q26863513 | ||
| Lithium in the treatment of bipolar disorder: pharmacology and pharmacogenetics | Q28081249 | ||
| KCNQ1, KCNE2, and Na+-coupled solute transporters form reciprocally regulating complexes that affect neuronal excitability | Q28235219 | ||
| Chronic treatment of human astrocytoma cells with lithium, carbamazepine or valproic acid decreases inositol uptake at high inositol concentrations but increases it at low inositol concentrations. | Q55476227 | ||
| p62, an autophagy hero or culprit? | Q57651356 | ||
| Lithium Selectively Inhibits Muscarinic Receptor-Stimulated Inositol Tetrakisphosphate Accumulation in Mouse Cerebral Cortex Slices | Q68393972 | ||
| The effects of lithium on myo-inositol levels in layers of frontal cerebral cortex, in cerebellum, and in corpus callosum of the rat | Q71304848 | ||
| Evidence that Lithium Alters Phosphoinositide Metabolism: Chronic Administration Elevates Primarily d-myo-Inositol-1-Phosphate in Cerebral Cortex of the Rat | Q72895389 | ||
| Scyllo-inositol in post-mortem brain of bipolar, unipolar and schizophrenic patients | Q73175546 | ||
| Effects of lithium on platelet membrane phosphoinositides in bipolar disorder patients: a pilot study | Q73734135 | ||
| IMPA1 is essential for embryonic development and lithium-like pilocarpine sensitivity | Q80220342 | ||
| Myo-inositol-1-phosphate (MIP) synthase inhibition: in-vivo study in rats | Q81166433 | ||
| Knockout mice in understanding the mechanism of action of lithium | Q43276570 | ||
| Receptor reserve of phosphoinositide-coupled muscarinic receptors in mouse hippocampus in vivo | Q43764345 | ||
| Lithium Effects on Inositol Phospholipids and Inositol Phosphates: Evaluation of an In Vivo Model for Assessing Polyphosphoinositide Turnover in Brain | Q43943459 | ||
| Effects of systemically administered lithium on phosphoinositide metabolism in rat brain, kidney, and testis | Q43953937 | ||
| Chronic treatment with both lithium and sodium valproate may normalize phosphoinositol cycle activity in bipolar patients | Q44204395 | ||
| A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin. | Q45306622 | ||
| Effects of lithium on phosphoinositide metabolism in vivo | Q46243044 | ||
| Acute intracerebroventricular inositol does not reverse the effect of chronic lithium treatment in the forced swim test | Q46366428 | ||
| An antidepressant behaviour in mice carrying a gene-specific InsP3R1, InsP3R2 and InsP3R3 protein knockdown | Q46425998 | ||
| Homozygote inositol transporter knockout mice show a lithium-like phenotype | Q46614951 | ||
| Lithium enhances accumulation of [3H]inositol radioactivity and mass of second messenger inositol 1,4,5-trisphosphate in monkey cerebral cortex slices. | Q46687322 | ||
| Differential expression, activity and regulation of the sodium/myo-inositol cotransporter in astrocyte cultures from different regions of the rat brain | Q47875347 | ||
| Inhibition of the high affinity myo-inositol transport system: a common mechanism of action of antibipolar drugs? | Q48116157 | ||
| Increased brain myo-inositol 1-phosphate in lithium-treated rats. | Q48375284 | ||
| Inhibition of the effect of lithium on brain inositol by atropine and scopolamine | Q48402278 | ||
| Differential effects of lithium on muscarinic receptor stimulation of inositol phosphates in rat cerebral cortex slices. | Q48439595 | ||
| The origin of myo‐inositol in brain, cerebrospinal fluid and choroid plexus | Q48443341 | ||
| Genetic variability at IMPA2, INPP1 and GSK3β increases the risk of suicidal behavior in bipolar patients. | Q48506659 | ||
| Intracerebroventricular myo-inositol antagonizes lithium-induced suppression of rearing behaviour in rats. | Q48858121 | ||
| Inositol as an add-on treatment for bipolar depression. | Q48949641 | ||
| Choline, myo-inositol and mood in bipolar disorder: a proton magnetic resonance spectroscopic imaging study of the anterior cingulate cortex. | Q48951990 | ||
| Controlled trials of inositol in psychiatry | Q28239498 | ||
| Depression: a new animal model sensitive to antidepressant treatments | Q28254150 | ||
| Neural and developmental actions of lithium: a unifying hypothesis | Q28254375 | ||
| Inositol trisphosphate and calcium signalling | Q28262867 | ||
| The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain | Q28263692 | ||
| Trehalose induced antidepressant-like effects and autophagy enhancement in mice | Q28290140 | ||
| Molecular actions and clinical pharmacogenetics of lithium therapy | Q28307770 | ||
| Myo-inositol attenuates two specific behavioral effects of acute lithium in rats | Q28325375 | ||
| Characterization of the null murine sodium/myo-inositol cotransporter 1 (Smit1 or Slc5a3) phenotype: myo-inositol rescue is independent of expression of its cognate mitochondrial ribosomal protein subunit 6 (Mrps6) gene and of [...] | Q28513344 | ||
| Loss of murine Na+/myo-inositol cotransporter leads to brain myo-inositol depletion and central apnea | Q28585058 | ||
| PIP2 and PIP3: complex roles at the cell surface | Q28609413 | ||
| The Beclin 1 network regulates autophagy and apoptosis | Q29616539 | ||
| Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium | Q30362607 | ||
| Differential sensitivity to lithium's reversal of amphetamine-induced open-field activity in two inbred strains of mice | Q31863580 | ||
| Decreased anterior cingulate myo-inositol/creatine spectroscopy resonance with lithium treatment in children with bipolar disorder | Q31969376 | ||
| A human myo-inositol monophosphatase gene (IMPA2) localized in a putative susceptibility region for bipolar disorder on chromosome 18p11.2: genomic structure and polymorphism screening in manic-depressive patients | Q33902758 | ||
| A common mechanism of action for three mood-stabilizing drugs | Q34128871 | ||
| The high affinity inositol transport system--implications for the pathophysiology and treatment of bipolar disorder | Q34185317 | ||
| Preclinical and clinical investigations of mood stabilizers for Huntington's disease: what have we learned? | Q34284039 | ||
| Examination of IMPA1 and IMPA2 genes in manic-depressive patients: association between IMPA2 promoter polymorphisms and bipolar disorder | Q34286895 | ||
| Phosphorylation of proteins by inositol pyrophosphates | Q34377316 | ||
| A promoter haplotype of the inositol monophosphatase 2 gene (IMPA2) at 18p11.2 confers a possible risk for bipolar disorder by enhancing transcription | Q34605987 | ||
| The effect of lithium on the adrenoceptor-mediated second messenger system in the rat brain. | Q34716497 | ||
| Lithium delays progression of amyotrophic lateral sclerosis | Q34746211 | ||
| Inositol, lithium, and the brain. | Q34979391 | ||
| Chronic treatment with lithium or valproate modulates the expression of Homer1b/c and its related genes Shank and Inositol 1,4,5-trisphosphate receptor. | Q35992454 | ||
| Lithium induces autophagy by inhibiting inositol monophosphatase | Q36321015 | ||
| Inositol-related gene knockouts mimic lithium's effect on mitochondrial function | Q37409627 | ||
| The Putative Use of Lithium in Alzheimer's Disease | Q38739790 | ||
| Lithium improves survival of PC12 pheochromocytoma cells in high-density cultures and after exposure to toxic compounds | Q39021456 | ||
| Antidepressive-like effects of rapamycin in animal models: Implications for mTOR inhibition as a new target for treatment of affective disorders | Q39275724 | ||
| The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1. | Q39867616 | ||
| The effects of acute and chronic lithium treatment on pilocarpine-stimulated phosphoinositide hydrolysis in mouse brain in vivo | Q41893041 | ||
| Lithium stimulates accumulation of second-messenger inositol 1,4,5-trisphosphate and other inositol phosphates in mouse pancreatic minilobules without inositol supplementation | Q41909715 | ||
| Li+ increases accumulation of inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate in cholinergically stimulated brain cortex slices in guinea pig, mouse and rat. The increases require inositol supplementation in mouse and rat but not | Q42792899 | ||
| Time-dependent effects of lithium on the agonist-stimulated accumulation of second messenger inositol 1,4,5-trisphosphate in SH-SY5Y human neuroblastoma cells | Q42822478 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 12 | |
| P304 | page(s) | e968 | |
| P577 | publication date | 2016-12-06 | |
| P1433 | published in | Translational Psychiatry | Q15716636 |
| P1476 | title | IP3 accumulation and/or inositol depletion: two downstream lithium's effects that may mediate its behavioral and cellular changes | |
| P478 | volume | 6 |
| Q94686319 | A novel function of IMPA2, plays a tumor-promoting role in cervical cancer |
| Q55405496 | Autophagy in Age-Associated Neurodegeneration. |
| Q92698941 | Dual Role of Autophagy in Diseases of the Central Nervous System |
| Q101051196 | Dynamic changes in the brain protein interaction network correlates with progression of Aβ42 pathology in Drosophila |
| Q98665104 | Inositol monophosphatase 1 (IMPA1) mutation in intellectual disability patients impairs neurogenesis but not gliogenesis |
| Q58782283 | Lithium and fluoxetine regulate the rate of phosphoinositide synthesis in neurons: a new view of their mechanisms of action in bipolar disorder |
| Q60919892 | Loss-of-function mutation in inositol monophosphatase 1 (IMPA1) results in abnormal synchrony in resting-state EEG |
| Q98465071 | The Role of Cathepsins in Memory Functions and the Pathophysiology of Psychiatric Disorders |
| Q99572006 | The influence of choline treatment on behavioral and neurochemical autistic-like phenotype in Mthfr-deficient mice |
| Q55262536 | The observed alteration in BCL2 expression following lithium treatment is influenced by the choice of normalization method. |
| Q60800989 | mTOR-Related Brain Dysfunctions in Neuropsychiatric Disorders |
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