Inositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicity

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Inositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicity is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1001899839
P356DOI10.1038/SREP07330
P3181OpenCitations bibliographic resource ID4878236
P932PMC publication ID4256660
P698PubMed publication ID25476455
P5875ResearchGate publication ID269187164

P2093author name stringWei Zhang
Hua Song
Susie Ahn
Aiguo Li
Hong Sug Kim
P2860cites workThe coiled-coil domain of Stat3 is essential for its SH2 domain-mediated receptor binding and subsequent activation induced by epidermal growth factor and interleukin-6Q24290231
Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cellsQ24293124
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphateQ24317714
Comprehensive genomic characterization defines human glioblastoma genes and core pathwaysQ24656128
The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancersQ28115840
Identification and characterization of a sac domain-containing phosphoinositide 5-phosphataseQ28117024
Specific inhibition of Stat3 signal transduction by PIAS3Q28255665
A Novel Sequence in the Coiled-coil Domain of Stat3 Essential for Its Nuclear TranslocationQ28505954
Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activityQ28508698
Inpp5f is a polyphosphoinositide phosphatase that regulates cardiac hypertrophic responsivenessQ28590549
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolismQ29547302
Stats: transcriptional control and biological impactQ29547776
STATs and gene regulationQ29547796
IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancerQ29614594
Stat3 as an oncogeneQ29614606
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell linesQ29615823
A randomized trial of bevacizumab for newly diagnosed glioblastomaQ30410163
STAT signaling in the pathogenesis and treatment of cancerQ33712802
Stat3 activation is required for cellular transformation by v-srcQ33786469
Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?.Q35120899
STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cellsQ35343534
Genetic pathways to primary and secondary glioblastomaQ35757144
Stat3 activation is limiting for reprogramming to ground state pluripotency.Q36282054
Tracking STAT nuclear trafficQ36547212
STAT3 as a central mediator of neoplastic cellular transformationQ36665485
Rembrandt: helping personalized medicine become a reality through integrative translational researchQ37103992
STAT3 regulation of glioblastoma pathogenesis.Q37550760
PI3K and STAT3: a new alliance.Q37986079
Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3.Q39560754
Stat3 activation by Src induces specific gene regulation and is required for cell transformationQ39583802
Activation of nonreceptor tyrosine kinase Bmx/Etk mediated by phosphoinositide 3-kinase, epidermal growth factor receptor, and ErbB3 in prostate cancer cellsQ40083890
Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cellsQ40685493
Phosphatidylinositol (3,4,5)P3 is essential but not sufficient for protein kinase B (PKB) activation; phosphatidylinositol (3,4)P2 is required for PKB phosphorylation at Ser-473: studies using cells from SH2-containing inositol-5-phosphatase knockouQ43847794
Regulation of Stat3 nuclear import by importin alpha5 and importin alpha7 via two different functional sequence elementsQ46812595
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectInositol polyphosphate-5-phosphatase FQ21122746
negative regulation of tyrosine phosphorylation of STAT proteinQ22245678
P304page(s)7330
P577publication date2014-12-05
P1433published inScientific ReportsQ2261792
P1476titleInositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicity
P478volume4

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cites work (P2860)
Q37376452BIS-mediated STAT3 stabilization regulates glioblastoma stem cell-like phenotypes.
Q37688839Coordination of signalling networks and tumorigenic properties by ABL in glioblastoma cells
Q55294157Exploring the molecular pathogenesis associated with T-cell prolymphocytic leukemia based on a comprehensive bioinformatics analysis.
Q28506127Gene-Silencing Screen for Mammalian Axon Regeneration Identifies Inpp5f (Sac2) as an Endogenous Suppressor of Repair after Spinal Cord Injury
Q92092479Locating potentially lethal genes using the abnormal distributions of genotypes
Q42002003Saw Palmetto Extract Inhibits Metastasis and Antiangiogenesis through STAT3 Signal Pathway in Glioma Cell
Q91657327Somatic mutation signatures in primary liver tumors of workers exposed to ionizing radiation

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