| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2009PNAS..106.9435V |
| P356 | DOI | 10.1073/PNAS.0900571106 |
| P8608 | Fatcat ID | release_7cz33pjigrc6npkrjicwfo6kzy |
| P3181 | OpenCitations bibliographic resource ID | 4298977 |
| P932 | PMC publication ID | 2687998 |
| P698 | PubMed publication ID | 19478061 |
| P50 | author | Chris Sander | Q5107972 |
| Timothy F. Cloughesy | Q47159504 | ||
| Philip Paty | Q59748411 | ||
| Linda Liau | Q59749173 | ||
| Paul Mischel | Q61594836 | ||
| Juliann Chmielecki | Q66809335 | ||
| Ingo K Mellinghoff | Q79440542 | ||
| Barry S. Taylor | Q88249464 | ||
| David B Solit | Q90267706 | ||
| Bhuvanesh Singh | Q91089154 | ||
| Adriana Heguy | Q100944806 | ||
| Selvaraju Veeriah | Q114291524 | ||
| Shasha Meng | Q114291525 | ||
| William Pao | Q28025149 | ||
| Marc Ladanyi | Q28468944 | ||
| Cameron Brennan | Q30502649 | ||
| Igor Vivanco | Q42690891 | ||
| Nikolaus Schultz | Q42862190 | ||
| P2093 | author name string | John Major | |
| Fang Fang | |||
| Dan Rohle | |||
| Timothy A. Chan | |||
| James A. Fagin | |||
| William L. Gerald | |||
| P2860 | cites work | Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T | Q24300141 |
| Structural requirements for signal transducer and activator of transcription 3 binding to phosphotyrosine ligands containing the YXXQ motif | Q24308065 | ||
| Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development | Q24317761 | ||
| Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands | Q24631957 | ||
| A census of human cancer genes | Q24647081 | ||
| Somatic mutations affect key pathways in lung adenocarcinoma | Q24648102 | ||
| Characterizing the cancer genome in lung adenocarcinoma | Q24649926 | ||
| Comprehensive genomic characterization defines human glioblastoma genes and core pathways | Q24656128 | ||
| Allelic imbalances and microdeletions affecting the PTPRD gene in cutaneous squamous cell carcinomas detected using single nucleotide polymorphism microarray analysis | Q24657188 | ||
| Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas | Q24669579 | ||
| Formation of intracranial tumors by genetically modified human astrocytes defines four pathways critical in the development of human anaplastic astrocytoma | Q46338106 | ||
| The fundamental role of epigenetic events in cancer | Q56421597 | ||
| Molecular and cytogenetic analysis of chromosome 9 deletions in 75 malignant gliomas | Q71608010 | ||
| The amino acid residues immediately carboxyl-terminal to the tyrosine phosphorylation site contribute to interleukin 6-specific activation of signal transducer and activator of transcription 3 | Q73182667 | ||
| Evidence for three tumor suppressor loci on chromosome 9p involved in melanoma development | Q73548869 | ||
| Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells | Q24802990 | ||
| Worms gang up on bacteria | Q27860588 | ||
| The consensus coding sequences of human breast and colorectal cancers | Q27861035 | ||
| Oncogenic kinase signalling | Q28189493 | ||
| DNMT1 and DNMT3b cooperate to silence genes in human cancer cells | Q28212826 | ||
| Principles of tumor suppression | Q28240740 | ||
| ONCOMINE: a cancer microarray database and integrated data-mining platform | Q28255103 | ||
| Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis | Q28472991 | ||
| Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6 | Q28637521 | ||
| Stat3 as an oncogene | Q29614606 | ||
| Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression | Q29615223 | ||
| Gene silencing in cancer in association with promoter hypermethylation | Q29617274 | ||
| Malignant astrocytic glioma: genetics, biology, and paths to treatment | Q29618156 | ||
| Cancer genetics. | Q34253580 | ||
| Mutational analysis of the tyrosine phosphatome in colorectal cancers | Q34322220 | ||
| Identification of chromosome arm 9p as the most frequent target of homozygous deletions in lung cancer | Q34444611 | ||
| Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia | Q36287377 | ||
| Protein-tyrosine phosphatases and cancer | Q36430193 | ||
| LLL-3 inhibits STAT3 activity, suppresses glioblastoma cell growth and prolongs survival in a mouse glioblastoma model | Q37080996 | ||
| Mutational inactivation of PTPRD in glioblastoma multiforme and malignant melanoma | Q37385138 | ||
| Optimal primer design using the novel primer design program: MSPprimer provides accurate methylation analysis of the ATM promoter. | Q38303382 | ||
| STAT3 silencing with lentivirus inhibits growth and induces apoptosis and differentiation of U251 cells | Q39931894 | ||
| JSI-124 inhibits glioblastoma multiforme cell proliferation through G(2)/M cell cycle arrest and apoptosis augment | Q39980916 | ||
| High-resolution analysis of chromosomal breakpoints and genomic instability identifies PTPRD as a candidate tumor suppressor gene in neuroblastoma | Q40296399 | ||
| Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis | Q40402337 | ||
| Homozygous deletion of CDKN2A and codeletion of the methylthioadenosine phosphorylase gene in the majority of pleural mesotheliomas. | Q40641261 | ||
| Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells | Q40685493 | ||
| CDKN2A is not the principal target of deletions on the short arm of chromosome 9 in neuroendocrine (Merkel cell) carcinoma of the skin | Q40795427 | ||
| Analysis of tumor suppressor gene on human chromosome 9 in mouse x human somatic cell hybrids | Q41445843 | ||
| Single nucleotide polymorphism array analysis defines a specific genetic fingerprint for well-differentiated cutaneous SCCs | Q41783160 | ||
| Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations. | Q44760563 | ||
| P433 | issue | 23 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | glioblastoma | Q282142 |
| P304 | page(s) | 9435–9440 | |
| P577 | publication date | 2009-06-09 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers | |
| P478 | volume | 106 |
| Q36379915 | A Joint Bayesian Model for Integrating Microarray and RNA Sequencing Transcriptomic Data |
| Q34065944 | A catalog of genes homozygously deleted in human lung cancer and the candidacy of PTPRD as a tumor suppressor gene. |
| Q37019200 | A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival |
| Q36778202 | Abundant copy-number loss of CYCLOPS and STOP genes in gastric adenocarcinoma |
| Q34536679 | Allelotypes of lung adenocarcinomas featuring ALK fusion demonstrate fewer onco- and suppressor gene changes |
| Q39022069 | Anti-EGFR therapeutic efficacy correlates directly with inhibition of STAT3 activity. |
| Q44943632 | Atypical neurofibromas in neurofibromatosis type 1 are premalignant tumors |
| Q92978027 | B4GALNT1 induces angiogenesis, anchorage independence growth and motility, and promotes tumorigenesis in melanoma by induction of ganglioside GM2/GD2 |
| Q92648079 | BMP10 suppresses hepatocellular carcinoma progression via PTPRS-STAT3 axis |
| Q37598464 | Cancer driver-passenger distinction via sporadic human and dog cancer comparison: a proof-of-principle study with colorectal cancer. |
| Q51769275 | Candidate genes involving in tumorigenesis of cholangiocarcinoma induced by Opisthorchis viverrini infection |
| Q37092245 | Characterization of differential protein tethering at the plasma membrane in response to epidermal growth factor signaling |
| Q37082568 | Classical pathology and mutational load of breast cancer - integration of two worlds |
| Q34186632 | Clear-cell papillary renal cell carcinoma: molecular and immunohistochemical analysis with emphasis on the von Hippel-Lindau gene and hypoxia-inducible factor pathway-related proteins. |
| Q37075035 | Critical analysis of the potential for targeting STAT3 in human malignancy |
| Q35386200 | Cross-talk between Phospho-STAT3 and PLCγ1 Plays a Critical Role in Colorectal Tumorigenesis |
| Q54323035 | D9S168 microsatellite alteration predicts a poor prognosis in patients with clear cell renal cell carcinoma and correlates with the down-regulation of protein tyrosine phosphatase receptor delta. |
| Q92406835 | DDIAS promotes STAT3 activation by preventing STAT3 recruitment to PTPRM in lung cancer cells |
| Q34334463 | Deletion of Ptprd and Cdkn2a cooperate to accelerate tumorigenesis |
| Q36030770 | Delving into somatic variation in sporadic melanoma |
| Q41390271 | Determinants of the extent and duration of STAT3 signaling |
| Q43528418 | Distinct Involvement of 9p21-24 and 13q14.1-14.3 Chromosomal Regions in Raw Betel-Nut Induced Esophageal Cancers in the State of Meghalaya, India |
| Q42730244 | Epigenetic Regulation of Wnt Pathway Antagonists in Human Glioblastoma Multiforme |
| Q83435245 | Epigenetic silencing of PTPRR activates MAPK signaling, promotes metastasis and serves as a biomarker of invasive cervical cancer |
| Q33790698 | Evaluation of microsatellite variation in the 1000 Genomes Project pilot studies is indicative of the quality and utility of the raw data and alignments |
| Q39298204 | Exploration of Involved Key Genes and Signaling Diversity in Brain Tumors |
| Q28115604 | Focal DNA copy number changes in neuroblastoma target MYCN regulated genes |
| Q41776703 | Frequent HRAS Mutations in Malignant Ectomesenchymoma: Overlapping Genetic Abnormalities With Embryonal Rhabdomyosarcoma |
| Q37519638 | Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer |
| Q39351446 | Functional Analysis of the Putative Tumor SuppressorPTPRDin Neuroblastoma Cells |
| Q36854427 | Gene deletions and amplifications in human hepatocellular carcinomas: correlation with hepatocyte growth regulation |
| Q55416344 | Genetic Insights Into Frailty: Association of 9p21-23 Locus With Frailty. |
| Q35001574 | Genetic alterations and signaling pathways in the evolution of gliomas |
| Q38255066 | Genetic alterations of protein tyrosine phosphatases in human cancers |
| Q42365255 | Genetic defects of the IRF1-mediated major histocompatibility complex class I antigen presentation pathway occur prevalently in the JAK2 gene in non-small cell lung cancer |
| Q34422582 | Genetic determinants at the interface of cancer and neurodegenerative disease |
| Q54940815 | Genetic overlap between endometriosis and endometrial cancer: evidence from cross-disease genetic correlation and GWAS meta-analyses. |
| Q37684508 | Genetic variants in PTPRD and risk of gestational diabetes mellitus. |
| Q35738663 | Genome-Wide Loss of Heterozygosity and DNA Copy Number Aberration in HPV-Negative Oral Squamous Cell Carcinoma and Their Associations with Disease-Specific Survival |
| Q36097570 | Genomic Alteration in Head and Neck Squamous Cell Carcinoma (HNSCC) Cell Lines Inferred from Karyotyping, Molecular Cytogenetics, and Array Comparative Genomic Hybridization. |
| Q86103494 | Genomic aberration patterns and expression profiles of squamous cell carcinomas of the vulva |
| Q33840816 | Genomic profiling of advanced-stage oral cancers reveals chromosome 11q alterations as markers of poor clinical outcome |
| Q33777454 | Genomics of Squamous Cell Lung Cancer |
| Q37132240 | Germline PTPRD mutations in Ewing sarcoma: biologic and clinical implications |
| Q39611034 | High resolution ArrayCGH and expression profiling identifies PTPRD and PCDH17/PCH68 as tumor suppressor gene candidates in laryngeal squamous cell carcinoma. |
| Q38950010 | Host genetic variants and gene expression patterns associated with Epstein-Barr virus copy number in lymphoblastoid cell lines. |
| Q84703029 | IL-6 activates STAT5 in T cells |
| Q34191958 | Identification and functional analysis of 9p24 amplified genes in human breast cancer |
| Q24646348 | Identification and functional characterization of paxillin as a target of protein tyrosine phosphatase receptor T |
| Q90317093 | Identification of Acer2 as a First Susceptibility Gene for Lithium-Induced Nephrogenic Diabetes Insipidus in Mice |
| Q33917547 | Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing |
| Q50988840 | In Vivo RNAi Screen for BMI1 Targets Identifies TGF-β/BMP-ER Stress Pathways as Key Regulators of Neural- and Malignant Glioma-Stem Cell Homeostasis |
| Q40980854 | Increased PTPRA expression leads to poor prognosis through c-Src activation and G1 phase progression in squamous cell lung cancer |
| Q36545999 | Increased metastasis with loss of E2F2 in Myc-driven tumors |
| Q28118996 | Inositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicity |
| Q34156227 | Inside the human cancer tyrosine phosphatome |
| Q36894394 | Integrated Genomics for Pinpointing Survival Loci within Arm-Level Somatic Copy Number Alterations. |
| Q33990951 | Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease |
| Q33950522 | Integration and analysis of genome-scale data from gliomas |
| Q34228757 | Integrative Analysis of N-Linked Human Glycoproteomic Data Sets Reveals PTPRF Ectodomain as a Novel Plasma Biomarker Candidate for Prostate Cancer |
| Q92964242 | Leveraging protein dynamics to identify cancer mutational hotspots using 3D structures |
| Q35565689 | Losing balance: Hardy-Weinberg disequilibrium as a marker for recurrent loss-of-heterozygosity in cancer |
| Q28584911 | Loss of the tyrosine phosphatase PTPRD leads to aberrant STAT3 activation and promotes gliomagenesis |
| Q27853197 | Loss-of-Function PTPRD Mutations Lead to Increased STAT3 Activation and Sensitivity to STAT3 Inhibition in Head and Neck Cancer |
| Q41472760 | Maintenance of cancer stemness by miR-196b-5p contributes to chemoresistance of colorectal cancer cells via activating STAT3 signaling pathway |
| Q52617931 | Metastatic cutaneous squamous cell carcinoma shows frequent deletion in the protein tyrosine phosphatase receptor Type D gene. |
| Q35032621 | Missing-in-Metastasis regulates cell motility and invasion via PTPδ-mediated changes in SRC activity |
| Q35382936 | Mutational and functional analysis of the tumor-suppressor PTPRD in human melanoma |
| Q26830388 | NF-κB and STAT3 in glioblastoma: therapeutic targets coming of age |
| Q92861949 | Negative regulators of STAT3 signaling pathway in cancers |
| Q24618920 | Novel human genetic variants associated with extrapulmonary tuberculosis: a pilot genome wide association study |
| Q35224188 | Novel secondary somatic mutations in Ewing's sarcoma and desmoplastic small round cell tumors |
| Q36677516 | PTPRD gene associated with blood pressure response to atenolol and resistant hypertension |
| Q35955186 | PTPRD silencing by DNA hypermethylation decreases insulin receptor signaling and leads to type 2 diabetes |
| Q91729236 | PTPRD-inactivation-induced CXCL8 promotes angiogenesis and metastasis in gastric cancer and is inhibited by metformin |
| Q37609203 | PTPRO represses ERBB2-driven breast oncogenesis by dephosphorylation and endosomal internalization of ERBB2 |
| Q45988269 | Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors. |
| Q50207491 | Polymorphism of receptor-type tyrosine-protein phosphatase delta gene in the development of non-alcoholic fatty liver disease |
| Q59333218 | Potential Epigenetic-Based Therapeutic Targets for Glioma |
| Q35934571 | Prognostic implication of PTPRH hypomethylation in non-small cell lung cancer. |
| Q64245074 | Protein Phosphatases-A Touchy Enemy in the Battle Against Glioblastomas: A Review |
| Q58749617 | Protein Tyrosine Phosphatases as Potential Regulators of STAT3 Signaling |
| Q50938980 | Protein Tyrosine Signaling and its Potential Therapeutic Implications in Carcinogenesis. |
| Q43768047 | Protein tyrosine phosphatase receptor R and Z1 expression as independent prognostic indicators in oral squamous cell carcinoma. |
| Q36092374 | Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase A oncogene. |
| Q34308099 | Protein tyrosine phosphatase receptor-like genes are frequently hypermethylated in sporadic colorectal cancer. |
| Q47152563 | Protein tyrosine phosphatase receptor-type δ acts as a negative regulator suppressing breast cancer |
| Q26861574 | Protein tyrosine phosphatases as wardens of STAT signaling |
| Q37638344 | Protein tyrosine phosphatases in glioma biology |
| Q53269470 | Protein tyrosine phosphatases receptor type D is a potential tumour suppressor gene inactivated by deoxyribonucleic acid methylation in paediatric acute myeloid leukaemia |
| Q24632905 | Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis |
| Q90240030 | RNA-seq as a tool for evaluating human embryo competence |
| Q24632928 | Recent advances in the molecular understanding of glioblastoma |
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| Q38710424 | Recurrent epigenetic silencing of the PTPRD tumor suppressor in laryngeal squamous cell carcinoma. |
| Q34550261 | Reduced expression of PTPRD correlates with poor prognosis in gastric adenocarcinoma |
| Q38962315 | Role of STAT3 in Genesis and Progression of Human Malignant Gliomas. |
| Q38116768 | STAT transcription factors in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention |
| Q38671957 | STAT3 Activation in Glioblastoma: Biochemical and Therapeutic Implications |
| Q38185622 | STAT3 and metabolism: how many ways to use a single molecule? |
| Q34154674 | STAT3 is activated by JAK2 independent of key oncogenic driver mutations in non-small cell lung carcinoma. |
| Q58762125 | Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine malignant melanoma by integrated comparative genomic analysis |
| Q35606411 | Specific genomic aberrations predict survival, but low mutation rate in cancer hot spots, in clear cell renal cell carcinoma |
| Q47715326 | Spectrum of germline mutations in smokers and non-smokers in Brazilian non-small-cell lung cancer (NSCLC) patients. |
| Q33921803 | Stat3: linking inflammation to epithelial cancer - more than a "gut" feeling? |
| Q35929525 | Studying a complex tumor: potential and pitfalls |
| Q34754045 | Tailoring tyrosine kinase inhibitors to fit the lung cancer genome. |
| Q35925127 | Targeting the Interleukin-6/Jak/Stat Pathway in Human Malignancies |
| Q55260605 | The Roles of Protein Tyrosine Phosphatases in Hepatocellular Carcinoma. |
| Q38687571 | The STAT3 pathway as a therapeutic target in head and neck cancer: Barriers and innovations |
| Q37243257 | The genetics of nodal marginal zone lymphoma |
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| Q37609740 | The prognostic role of intragenic copy number breakpoints and identification of novel fusion genes in paediatric high grade glioma |
| Q43276275 | The protein tyrosine phosphatase receptor D, a broadly inactivated tumor suppressor regulating STAT function. |
| Q38090432 | The regulatory roles of phosphatases in cancer |
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| Q55082067 | Tobacco habituated and non-habituated subjects exhibit different mutational spectrums in head and neck squamous cell carcinoma. |
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