Characterizing the cancer genome in lung adenocarcinoma

scientific article

Characterizing the cancer genome in lung adenocarcinoma is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1019681472
P356DOI10.1038/NATURE06358
P3181OpenCitations bibliographic resource ID544819
P932PMC publication ID2538683
P698PubMed publication ID17982442
P5875ResearchGate publication ID5865101

P50authorHarold E. VarmusQ295691
Elaine MardisQ5353251
George WeinstockQ5546130
Eric LanderQ970550
Richard K. WilsonQ16193441
Marc LadanyiQ28468944
Brad OzenbergerQ32414699
Gad GetzQ32646381
Wendy WincklerQ32646521
Heidi GreulichQ32646847
Stacey GabrielQ32649203
Frances A. ShepherdQ27430461
William PaoQ28025149
Carrie SougnezQ28321195
Matthew MeyersonQ47451221
Ming-Sound TsaoQ47492209
Aldi KrajaQ114291517
Margaret B MorganQ115165680
Alex H RamosQ123348827
Mark RubinQ37375521
John McPhersonQ37391589
Mark G KrisQ37621431
Andrew C. ChangQ37621533
Thomas GiordanoQ37621567
Alex LashQ37621599
Hanna WallachQ44651811
Valerie W RuschQ51775643
Akihiko YoshizawaQ57696572
John MinnaQ59751541
Richard A GibbsQ64856497
Ignacio I WistubaQ74766086
David G BeerQ87761086
Margaret SpitzQ87847501
Rameen BeroukhimQ88043871
Michael A ProvinceQ88244370
Roel G W VerhaakQ88447576
Ingrid B BoreckiQ89095223
Sven PernerQ89425842
Levi A GarrawayQ89916155
David A. WheelerQ91473919
Lucian R ChirieacQ92353485
Jack A RothQ104479118
Barbara A WeirQ106967220
Mark B. OrringerQ112545944
Maureen F ZakowskiQ114291510
Adi F GazdarQ114291514
Qunyuan ZhangQ114291516
P2093author name stringJames Robinson
Li Ding
Roman K Thomas
William D Travis
Bruce E Johnson
Derek Y Chiang
Laura A Johnson
Michele S Woo
Neal Lindeman
Justine A Barletta
Ling Lin
Stephen Broderick
Kinjal Shah
Mark A Watson
Mitsuo Sato
Yoshitaka Fujii
Hidefumi Sasaki
William M Lin
Mark Nadel
John R Osborne
Jeonghee Cho
Soyoung Yu
David Twomey
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P275copyright licenseCreative Commons Attribution-NonCommercial-ShareAlike 3.0 UnportedQ15643954
P6216copyright statuscopyrightedQ50423863
P433issue7171
P407language of work or nameEnglishQ1860
P921main subjectadenocarcinomaQ356033
adenocarcinoma of the lungQ843799
P304page(s)893-898
P577publication date2007-11-04
P1433published inNatureQ180445
P1476titleCharacterizing the cancer genome in lung adenocarcinoma
P478volume450

Reverse relations

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Q89555553High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations
Q35096589High-mobility group A2 protein modulates hTERT transcription to promote tumorigenesis.
Q33440056High-resolution analysis of copy number alterations and associated expression changes in ovarian tumors
Q80856831High-resolution genomic and expression analyses of copy number alterations in breast tumors
Q34050186High-throughput genotyping in osteosarcoma identifies multiple mutations in phosphoinositide-3-kinase and other oncogenes
Q34541232High-throughput mutation profiling of primary and metastatic endometrial cancers identifies KRAS, FGFR2 and PIK3CA to be frequently mutated
Q37068513Highly parallel identification of essential genes in cancer cells
Q27312570Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics
Q37466158Homozygous inactivating mutations in the NKX3-2 gene result in spondylo-megaepiphyseal-metaphyseal dysplasia
Q37065678How Genetically Engineered Mouse Tumor Models Provide Insights Into Human Cancers
Q33554201Human cancers express mutator phenotypes: origin, consequences and targeting
Q37385838Hybridization modeling of oligonucleotide SNP arrays for accurate DNA copy number estimation.
Q30351902Hypothesis driven single nucleotide polymorphism search (HyDn-SNP-S).
Q38659248ICRP Publication 131: Stem Cell Biology with Respect to Carcinogenesis Aspects of Radiological Protection
Q35631086IGDB.NSCLC: integrated genomic database of non-small cell lung cancer
Q30877356Identification and preliminary characterization of novel small molecules that inhibit growth of human lung adenocarcinoma cells
Q34207099Identification of DOK genes as lung tumor suppressors
Q35032328Identification of EGFR expression status association with metastatic lymph node density (ND) by expression microarray analysis of advanced gastric cancer
Q37262522Identification of PDE4D as a proliferation promoting factor in prostate cancer using a Sleeping Beauty transposon-based somatic mutagenesis screen
Q39035797Identification of ZDHHC14 as a novel human tumour suppressor gene.
Q38762535Identification of an NKX3.1-G9a-UTY transcriptional regulatory network that controls prostate differentiation
Q36011694Identification of cancer-driver genes in focal genomic alterations from whole genome sequencing data
Q55027358Identification of copy number alterations in colon cancer from analysis of amplicon-based next generation sequencing data.
Q34504751Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers
Q64941057Identification of key pathways and genes in lung carcinogenesis.
Q35152155Identification of logic relationships between genes and subtypes of non-small cell lung cancer.
Q33705551Identification of lung cancer with high sensitivity and specificity by blood testing
Q35166315Identification of oncogenic point mutations and hyperphosphorylation of anaplastic lymphoma kinase in lung cancer.
Q38717741Identification of proteasomal catalytic subunit PSMA6 as a therapeutic target for lung cancer.
Q35256884Identification of regulatory SNPs associated with genetic modifications in lung adenocarcinoma.
Q98177113Identification of relevant genetic alterations in cancer using topological data analysis
Q34787147Identification of the NEDD4L Gene as a Prognostic Marker by Integrated Microarray Analysis of Copy Number and Gene Expression Profiling in Non-small Cell Lung Cancer
Q42513461Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth
Q41090797Identifying CDKN3 Gene Expression as a Prognostic Biomarker in Lung Adenocarcinoma via Meta-analysis.
Q26781810Identifying activating mutations in the EGFR gene: prognostic and therapeutic implications in non-small cell lung cancer
Q36050371Imaging of Lung Cancer in the Era of Molecular Medicine
Q38323055Immunohistochemistry-based prognostic biomarkers in NSCLC: novel findings on the road to clinical use?
Q33988646Impact on disease development, genomic location and biological function of copy number alterations in non-small cell lung cancer.
Q36331013In Situ Conversion of Melanoma Lesions into Autologous Vaccine by Intratumoral Injections of α-gal Glycolipids
Q37355404In vivo/ex vivo and in situ assays used in cancer research: a brief review
Q34993692Increased BRAF copy number in lung adenocarcinoma
Q35926926Increased MET gene copy number negatively affects survival of surgically resected non-small-cell lung cancer patients
Q86073879Individualized chemotherapy for osteosarcoma and identification of gene mutations in osteosarcoma
Q37980724Inhibition and Termination of Physiological Responses by GTPase Activating Proteins
Q64895040Inhibition of mPGES-1 or COX-2 Results in Different Proteomic and Lipidomic Profiles in A549 Lung Cancer Cells.
Q27851654Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer
Q36240493Integrated Analysis of Genome-Wide Copy Number Alterations and Gene Expression Profiling of Lung Cancer in Xuanwei, China
Q36894394Integrated Genomics for Pinpointing Survival Loci within Arm-Level Somatic Copy Number Alterations.
Q52629222Integrated Oncogenomic Profiling of Copy Numbers and Gene Expression in Lung Adenocarcinomas without EGFR Mutations or ALK Fusion
Q34026325Integrated analyses of copy number variations and gene expression in lung adenocarcinoma
Q24649562Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers
Q36592406Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target
Q60910638Integrated landscape of copy number variation and RNA expression associated with nodal metastasis in invasive ductal breast carcinoma
Q34786771Integrating differentiation and cancer: the Nkx3.1 homeobox gene in prostate organogenesis and carcinogenesis
Q36152246Integrating the multiple dimensions of genomic and epigenomic landscapes of cancer
Q90715196Integrative Genomic Analyses Identifies GGA2 as a Cooperative Driver of EGFR-Mediated Lung Tumorigenesis
Q35837786Integrative Genomics Implicates EGFR as a Downstream Mediator in NKX2-1 Amplified Non-Small Cell Lung Cancer
Q43889503Integrative analysis of genome-wide gene copy number changes and gene expression in non-small cell lung cancer.
Q33644421Integrative genomic analyses identify BRF2 as a novel lineage-specific oncogene in lung squamous cell carcinoma
Q37216672Integrative genomic approaches to understanding cancer.
Q29619905Integrative genomic profiling of human prostate cancer
Q39134067Inter-cellular adhesion disruption and the RAS/RAF and beta-catenin signalling in lung cancer progression
Q28303718International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma
Q35219746Intersections between Pulmonary Development and Disease
Q91649995Intratumor Heterogeneity in Early Lung Adenocarcinoma
Q38356968Intratumoral injection of alpha-gal glycolipids induces a protective anti-tumor T cell response which overcomes Treg activity
Q24570128Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls
Q33557528JISTIC: identification of significant targets in cancer.
Q37384068KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling.
Q28242884KRAS mutant allele-specific imbalance in lung adenocarcinoma
Q36464999KRAS mutation-positive bronchial surface epithelium (BSE)-type lung adenocarcinoma with strong expression of TTF-1: a case providing a further insight as for the role of TTF-1 in the oncogenesis
Q92003211Keratin 14-high subpopulation mediates lung cancer metastasis potentially through Gkn1 upregulation
Q24303485Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung
Q37850361LKB1 in lung cancerigenesis: a serine/threonine kinase as tumor suppressor
Q39101598LKB1 loss by alteration of the NKX2-1/p53 pathway promotes tumor malignancy and predicts poor survival and relapse in lung adenocarcinomas
Q36865568LKB1/STK11 inactivation leads to expansion of a prometastatic tumor subpopulation in melanoma
Q37377962Lack of inherited mutations of PTPRD in familial melanoma and melanoma-astrocytoma syndrome
Q44292546Landscape of somatic allelic imbalances and copy number alterations in human lung carcinoma
Q55485409Landscape of transcriptional deregulation in lung cancer.
Q38094259Lessons from the Cancer Genome
Q36943760Lessons from the first comprehensive molecular characterization of cell cycle control in rodent insulinoma cell lines
Q38395972Lineage factors and differentiation states in lung cancer progression
Q35565689Losing balance: Hardy-Weinberg disequilibrium as a marker for recurrent loss-of-heterozygosity in cancer
Q33956097Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression
Q37708984Loss of phosphodiesterase 4D mediates acquired triapine resistance via Epac-Rap1-Integrin signaling.
Q37428082Loss-of-function of an Arabidopsis NADPH pyrophosphohydrolase, AtNUDX19, impacts on the pyridine nucleotides status and confers photooxidative stress tolerance.
Q34281228Lung Adenocarcinoma From East Asian Never-Smokers Is a Disease Largely Defined by Targetable Oncogenic Mutant Kinases
Q82448154Lung Adenocarcinomas with HER2-Activating Mutations Are Associated with Distinct Clinical Features and HER2/EGFR Copy Number Gains
Q34110617Lung Cancer Cell Lines as Tools for Biomedical Discovery and Research
Q34193618Lung adenocarcinoma of never smokers and smokers harbor differential regions of genetic alteration and exhibit different levels of genomic instability
Q51081160Lung adenocarcinoma subtypes definable by lung development-related miRNA expression profiles in association with clinicopathologic features.
Q28754732Lung cancer and chronic obstructive pulmonary disease: needs and opportunities for integrated research
Q37487153Lung cancer biology: a genetic and genomic perspective.
Q35033316Lung cancer cell lines: Useless artifacts or invaluable tools for medical science?
Q37023811Lung cancer in never smokers: a call to action
Q34177155Lung cancer in never smokers: molecular profiles and therapeutic implications
Q35861107Lung cancer in the era of precision medicine
Q35636924Lung cancer mutations and use of targeted agents in Hispanics
Q24628852Lung cancer signatures in plasma based on proteome profiling of mouse tumor models
Q34094849Lung cancer: developmental networks gone awry?
Q34432733Lung injury and lung cancer caused by cigarette smoke-induced oxidative stress: Molecular mechanisms and therapeutic opportunities involving the ceramide-generating machinery and epidermal growth factor receptor.
Q99608553MBIP (MAP3K12 binding inhibitory protein) drives NSCLC metastasis by JNK-dependent activation of MMPs
Q24646295MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
Q24297454MYBPH, a transcriptional target of TTF-1, inhibits ROCK1, and reduces cell motility and metastasis
Q36166125MYC and human telomerase gene (TERC) copy number gain in early-stage non-small cell lung cancer
Q33820617MYCxing it up with FGFR1 in squamous cell lung cancer
Q64136466MYEOV functions as an amplified competing endogenous RNA in promoting metastasis by activating TGF-β pathway in NSCLC
Q89777623Maintenance of telomere length in AML
Q33329722Major copy proportion analysis of tumor samples using SNP arrays
Q33846850Making sense of cancer genomic data
Q28275103Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing
Q38010665Measuring molecular biomarkers in epidemiologic studies: laboratory techniques and biospecimen considerations
Q39911616Met gene copy number predicts the prognosis for completely resected non-small cell lung cancer
Q47735795Meta-analysis of mRNA expression profiles to identify differentially expressed genes in lung adenocarcinoma tissue from smokers and non-smokers
Q52617931Metastatic cutaneous squamous cell carcinoma shows frequent deletion in the protein tyrosine phosphatase receptor Type D gene.
Q47761912Metformin as a repurposed therapy in advanced non-small cell lung cancer (NSCLC): results of a phase II trial.
Q34241853MiR-365 regulates lung cancer and developmental gene thyroid transcription factor 1
Q37702742MicroRNA expression profiles and clinicopathological implications in lung adenocarcinoma according to EGFR, KRAS, and ALK status
Q39041572MicroRNA-198 inhibits proliferation and induces apoptosis of lung cancer cells via targeting FGFR1.
Q36910037MicroRNA-33a Mediates the Regulation of High Mobility Group AT-Hook 2 Gene (HMGA2) by Thyroid Transcription Factor 1 (TTF-1/NKX2–1)
Q38005062MicroRNAs and lung cancers: from pathogenesis to clinical implications
Q42833899Mina53, a novel c-Myc target gene, is frequently expressed in lung cancers and exerts oncogenic property in NIH/3T3 cells
Q39210492Molecular Dissection of AKT Activation in Lung Cancer Cell Lines
Q24610335Molecular biology of lung cancer: clinical implications
Q33468458Molecular characterization of lung dysplasia induced by c-Raf-1.
Q56795277Molecular classification of nonsmall cell lung cancer using a 4-protein quantitative assay
Q38716717Molecular definition of a metastatic lung cancer state reveals a targetable CD109-Janus kinase-Stat axis
Q37200438Molecular inversion probe analysis detects novel copy number alterations in Ewing sarcoma
Q37919395Molecular oncology of lung cancer
Q33688872Molecular pathways and therapeutic targets in lung cancer
Q34608584Molecular therapeutic advances in personalized therapy of melanoma and non-small cell lung cancer
Q54648969Morphological and molecular pathology of lung cancer
Q34205443Mouse models of cancers: opportunities to address heterogeneity of human cancer and evaluate therapeutic strategies.
Q38245669Moving from histological subtyping to molecular characterization: new treatment opportunities in advanced non-small-cell lung cancer
Q37150862MtDNA mutation pattern in tumors and human evolution are shaped by similar selective constraints.
Q96128436Multifunctional magnetic iron oxide nanoparticles: an advanced platform for cancer theranostics
Q28237604Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma
Q82905302Multiplexed analysis of angiogenesis and lymphangiogenesis factors predicts outcome for non-small cell lung cancer patients
Q35382936Mutational and functional analysis of the tumor-suppressor PTPRD in human melanoma
Q36031579Mutational heterogeneity in human cancers: origin and consequences.
Q37385138Mutational inactivation of PTPRD in glioblastoma multiforme and malignant melanoma
Q37369422Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma
Q24338837NIRF constitutes a nodal point in the cell cycle network and is a candidate tumor suppressor
Q37957618NKL homeobox genes in leukemia.
Q58695806NKX2-1-AS1 negatively regulates CD274/PD-L1, cell-cell interaction genes, and limits human lung carcinoma cell migration
Q35987328NKX2-1-mediated p53 expression modulates lung adenocarcinoma progression via modulating IKKβ/NF-κB activation
Q24308684NKX2-1/TITF1/TTF-1-Induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma
Q38114206NKX2-1/TTF-1: An Enigmatic Oncogene that Functions as a Double-Edged Sword for Cancer Cell Survival and Progression
Q24317081NKX3.1 activates expression of insulin-like growth factor binding protein-3 to mediate insulin-like growth factor-I signaling and cell proliferation
Q34428676NOTCH1, HIF1A and Other Cancer-Related Proteins in Lung Tissue from Uranium Miners—Variation by Occupational Exposure and Subtype of Lung Cancer
Q44337507Napsin A is an independent prognostic factor in surgically resected adenocarcinoma of the lung
Q40725339Network-Based Logistic Classification with an Enhanced L 1/2 Solver Reveals Biomarker and Subnetwork Signatures for Diagnosing Lung Cancer
Q37340439New applications and developments in the use of multiplex ligation-dependent probe amplification
Q34161395New driver mutations in non-small-cell lung cancer
Q42271046New lung cancer panel for high-throughput targeted resequencing
Q21183966New strategies and emerging technologies for massively parallel sequencing: applications in medical research
Q34544846Next generation sequencing analysis of platinum refractory advanced germ cell tumor sensitive to Sunitinib (Sutent®) a VEGFR2/PDGFRβ/c-kit/ FLT3/RET/CSF1R inhibitor in a phase II trial
Q36458217Next generation sequencing in clinical medicine: Challenges and lessons for pathology and biomedical informatics
Q37138662Next-generation sequencing of paired tyrosine kinase inhibitor-sensitive and -resistant EGFR mutant lung cancer cell lines identifies spectrum of DNA changes associated with drug resistance
Q37041088Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma
Q26995181Nkx2-1: a novel tumor biomarker of lung cancer
Q49787050Nkx2-3-A Slippery Slope From Development Through Inflammation Toward Hematopoietic Malignancies.
Q36217272Occludin Is a Direct Target of Thyroid Transcription Factor-1 (TTF-1/NKX2–1)
Q27023347Omics of Cancer
Q33510334Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells
Q28082384Oncogenic Signaling Adaptor Proteins
Q27852873Oncogenic and sorafenib-sensitive ARAF mutations in lung adenocarcinoma
Q38213830Oncogenic drivers, targeted therapies, and acquired resistance in non-small-cell lung cancer
Q27023342One mouse, one patient paradigm: New avatars of personalized cancer therapy
Q37410396One-step immortalization of primary human airway epithelial cells capable of oncogenic transformation.
Q48632489Opposite roles of FOXA1 and NKX2-1 in lung cancer progression
Q40844290Optimizing copy number variation analysis using genome-wide short sequence oligonucleotide arrays
Q38073157Other signalization targets
Q35368205Our changing view of the genomic landscape of cancer
Q34612346Overexpression of MEOX2 and TWIST1 is associated with H3K27me3 levels and determines lung cancer chemoresistance and prognosis
Q38578968Overview of KRAS-Driven Genetically Engineered Mouse Models of Non-Small Cell Lung Cancer
Q64280891PAX8 regulon in human ovarian cancer links lineage dependency with epigenetic vulnerability to HDAC inhibitors
Q92497822PD-L1 and PD-L2 expression correlated genes in non-small-cell lung cancer
Q33511182PICNIC: an algorithm to predict absolute allelic copy number variation with microarray cancer data
Q64053991PITX2 enhances progression of lung adenocarcinoma by transcriptionally regulating WNT3A and activating Wnt/β-catenin signaling pathway
Q60922787PSPH Mediates the Metastasis and Proliferation of Non-small Cell Lung Cancer through MAPK Signaling Pathways
Q28240702PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR
Q37666205Pan-cancer patterns of somatic copy number alteration
Q44748335Parallel evolution of tumour subclones mimics diversity between tumours
Q37389526Pathogenesis of lung cancer signalling pathways: roadmap for therapies
Q48322740Paul Ehrlich's magic bullet concept: 100 years of progress
Q35037810Performance of common analysis methods for detecting low-frequency single nucleotide variants in targeted next-generation sequence data
Q37909661Personalized Therapy for Non–Small Cell Lung Cancer: Hype or Clinical Reality?
Q37776547Personalized therapies in the cancer "omics" era
Q37080513Personalizing lung cancer prevention through a reverse migration strategy
Q35058948Pleiomorphic adenoma gene-like 2 expression is associated with the development of lung adenocarcinoma and emphysema
Q37620148Polycomb group proteins: navigators of lineage pathways led astray in cancer
Q37327531Precise inference of copy number alterations in tumor samples from SNP arrays
Q37742635Precision medicine driven by cancer systems biology
Q37209222Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions
Q37695981Preprocessing and downstream analysis of microarray DNA copy number profiles
Q92107648Prevalence of the epidermal growth factor receptor mutations in lung adenocarcinoma patients from the Middle East region
Q34171479Principles and strategies for developing network models in cancer
Q33692550Probability Theory-Based SNP Association Study Method for Identifying Susceptibility Loci and Genetic Disease Models in Human Case-Control Data
Q30694445Progenetix: 12 years of oncogenomic data curation
Q36060090Prognostic Value of Baseline 18F-FDG PET/CT Functional Parameters in Patients with Advanced Lung Adenocarcinoma Stratified by EGFR Mutation Status
Q30497419Prognostic and predictive gene signature for adjuvant chemotherapy in resected non-small-cell lung cancer
Q38493294Prognostic and predictive value of MET deregulation in non-small cell lung cancer
Q40155594Prognostic impact of TTF-1 expression in patients with stage IV lung adenocarcinomas.
Q36141851Prolonged early G1 arrest by selective CDK4/CDK6 inhibition sensitizes myeloma cells to cytotoxic killing through cell cycle–coupled loss of IRF4
Q37775627Prospects for molecular staging of non-small-cell lung cancer from genomic alterations
Q27307731Proteasome inhibitors block DNA repair and radiosensitize non-small cell lung cancer
Q53269470Protein tyrosine phosphatases receptor type D is a potential tumour suppressor gene inactivated by deoxyribonucleic acid methylation in paediatric acute myeloid leukaemia
Q28395348Pulmonary adenocarcinoma: A renewed entity in 2011
Q91676950RB constrains lineage fidelity and multiple stages of tumour progression and metastasis
Q92542047Ras Downstream Effector GGCT Alleviates Oncogenic Stress
Q34773458Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer
Q38643392Receptor tyrosine kinase-like orphan receptor 1, a target of NKX2-1/TTF-1 lineage-survival oncogene, inhibits apoptosis signal-regulating kinase 1-mediated pro-apoptotic signaling in lung adenocarcinoma
Q52653017Recurrent copy number alterations in young women with breast cancer.
Q64044073Recurrent genomic aberrations combined with deletions of various tumour suppressor genes may deregulate the G1/S transition in CD4+CD56+ haematodermic neoplasms and contribute to the aggressiveness of the disease
Q33472669Recurrent genomic gains in preinvasive lesions as a biomarker of risk for lung cancer
Q34550261Reduced expression of PTPRD correlates with poor prognosis in gastric adenocarcinoma
Q53121013Reflections on the Founding of the International Cancer Genome Consortium
Q28603652Registered report: Diverse somatic mutation patterns and pathway alterations in human cancers
Q38004927Regulation of Parkin E3 ubiquitin ligase activity.
Q39384713Regulation of TPD52 by antitumor microRNA-218 suppresses cancer cell migration and invasion in lung squamous cell carcinoma.
Q36650250Regulation of Transient Site-specific Copy Gain by MicroRNA.
Q53233695Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development.
Q38164307Regulatory variation: an emerging vantage point for cancer biology
Q34637846Relationship of thyroid transcription factor 1 to EGFR status in non-small-cell lung cancer
Q54333038Reliability of tumor primary cultures as a model for drug response prediction: expression profiles comparison of tissues versus primary cultures from colorectal cancer patients
Q35063579Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients
Q26826821Research progress of thyroid transcription factor-1 as molecular marker in lung carcinoma
Q35668629Rewiring of human lung cell lineage and mitotic networks in lung adenocarcinomas.
Q37956397Role of genotyping in non-small cell lung cancer treatment: current status
Q36953349SH3GL2 is frequently deleted in non-small cell lung cancer and downregulates tumor growth by modulating EGFR signaling
Q28587694SIRT4 has tumor-suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism
Q57693361SOX2 gene amplification and protein overexpression are associated with better outcome in squamous cell lung cancer
Q30491937SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
Q90043990SOX2 mediates cisplatin resistance in small-cell lung cancer with downregulated expression of hsa-miR-340-5p
Q34176566Secretoglobin 3A2/uteroglobin-related protein 1 is a novel marker for pulmonary carcinoma in mice and humans
Q33367138Segmental duplications arise from Pol32-dependent repair of broken forks through two alternative replication-based mechanisms
Q33312522Sex, dose, and equality
Q90609854ShinyCNV: a Shiny/R application to view and annotate DNA copy number variations
Q38974422Shisa3 is associated with prolonged survival through promoting β-catenin degradation in lung cancer
Q34143340Should we continue to use the term non-small-cell lung cancer?
Q39737975Signatures of mutation and selection in the cancer genome
Q36886177Significant frequency of allelic imbalance in 3p region covering RARβ and MLH1 loci seems to be essential in molecular non-small cell lung cancer diagnosis
Q33934743Simultaneous inhibition of key growth pathways in melanoma cells and tumor regression by a designed bidentate constrained helical peptide
Q33902184Single nucleotide polymorphism-based genome-wide chromosome copy change, loss of heterozygosity, and aneuploidy in Barrett's esophagus neoplastic progression
Q39127721Sirt3 is a tumor suppressor in lung adenocarcinoma cells
Q39565398Small-molecule binding sites to explore protein-protein interactions in the cancer proteome
Q37287242Smoking-related genomic signatures in non-small cell lung cancer
Q36214274Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study.
Q24648102Somatic mutations affect key pathways in lung adenocarcinoma
Q42713219Somatic mutations in cancer development
Q39009613Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies
Q34073818Sox2 protein expression is an independent poor prognostic indicator in stage I lung adenocarcinoma.
Q34442770Spatial and temporal diversity in genomic instability processes defines lung cancer evolution
Q37236636Specificity in cancer immunotherapy
Q28742090Spectrum of Oncogenic Driver Mutations in Lung Adenocarcinomas from East Asian Never Smokers
Q47715326Spectrum of germline mutations in smokers and non-smokers in Brazilian non-small-cell lung cancer (NSCLC) patients.
Q36909843Squamous Cell Cancers: A Unified Perspective on Biology and Genetics
Q27026425Squamous Cell Carcinoma of the Lung: Molecular Subtypes and Therapeutic Opportunities
Q37132800State of the art in tumor antigen and biomarker discovery.
Q42273036Stromal control of oncogenic traits expressed in response to the overexpression of GLI2, a pleiotropic oncogene
Q34163784Strong expression of IGF1R in pediatric gastrointestinal stromal tumors without IGF1R genomic amplification
Q38035556Structural mutations in cancer: mechanistic and functional insights
Q27680966Structural, Biochemical, and Clinical Characterization of Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations in Lung Cancer
Q35008652SubPatCNV: approximate subspace pattern mining for mapping copy-number variations
Q34939788Suppression of lung adenocarcinoma progression by Nkx2-1
Q35134003Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer
Q34345632TAGCNA: A Method to Identify Significant Consensus Events of Copy Number Alterations in Cancer
Q35370365TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer
Q27851543TSC1 loss synergizes with KRAS activation in lung cancer development in the mouse and confers rapamycin sensitivity.
Q48247270TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas.
Q34754045Tailoring tyrosine kinase inhibitors to fit the lung cancer genome.
Q37851009Taming the dragon: genomic biomarkers to individualize the treatment of cancer.
Q57327189Targeted Genomic Screen Reveals Focal Long Non-Coding RNA Copy Number Alterations in Cancer Cell Lines
Q34149286Targeted Therapies for Thymic Malignancies
Q92337932Targeted deep sequencing from multiple sources demonstrates increased NOTCH1 alterations in lung cancer patient plasma
Q36928888Targeted therapies for hepatocellular carcinoma.
Q36054970Targeted therapies for lung cancer: clinical experience and novel agents
Q37410635Targeting SOD1 reduces experimental non–small-cell lung cancer
Q33347458Telomeres and disease
Q35919877The 8q24 gene desert: an oasis of non-coding transcriptional activity.
Q37132018The Complexity of Thyroid Transcription Factor 1 with Both Pro- and Anti-oncogenic Activities
Q35400332The E3 ubiquitin ligase Trim7 mediates c-Jun/AP-1 activation by Ras signalling
Q40289758The EGFR family members sustain the neoplastic phenotype of ALK+ lung adenocarcinoma via EGR1.
Q37809678The Evolving Role of Histology in the Management of Advanced Non–Small-Cell Lung Cancer
Q41891513The Genomics of Lung Adenocarcinoma: Opportunities for Targeted Therapies
Q34456234The UCSC Cancer Genomics Browser: update 2011
Q37018751The chromosome 3p21.3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development
Q36450685The clinical pathological characteristics and prognosis of FGFR1 gene amplification in non-small-cell lung cancer: a meta-analysis
Q34129229The detection of chromosomal aneusomy by fluorescence in situ hybridization in sputum predicts lung cancer incidence
Q35083049The essential role of evasion from cell death in cancer
Q37462617The expression of AIP-related molecules in elucidation of cellular pathways in pituitary adenomas
Q38296670The hypoxic tumor microenvironment: driving the tumorigenesis of non-small-cell lung cancer
Q29547648The landscape of somatic copy-number alteration across human cancers
Q37703901The molecular genetic basis of ovarian cancer and its roadmap towards a better treatment
Q34117627The mutation spectrum revealed by paired genome sequences from a lung cancer patient
Q35216054The potential utility of telomere‐related markers for cancer diagnosis
Q36906563The prognostic and predictive value of KRAS oncogene substitutions in lung adenocarcinoma
Q90612096The prognostic effect of TTF-1 expression in the Chinese population of patients with advanced lung adenocarcinomas
Q37296558The role of AUTS2 in neurodevelopment and human evolution
Q37900640The role of inflammation in the pathogenesis of lung cancer
Q28083838The role of splicing factors in deregulation of alternative splicing during oncogenesis and tumor progression
Q28246658The somatic genomic landscape of chromophobe renal cell carcinoma
Q36354852The transcriptional landscape and mutational profile of lung adenocarcinoma.
Q28115840The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers
Q36615870Thyroid Transcription Factor 1 Reprograms Angiogenic Activities of Secretome.
Q82099060Thyroid Transcription Factor-1 Amplification and Expressions in Lung Adenocarcinoma Tissues and Pleural Effusions Predict Patient Survival and Prognosis
Q88091776Thyroid transcription factor 1 enhances cellular statin sensitivity via perturbing cholesterol metabolism
Q36642670Thyroid transcription factor 1 represses the expression of Ki-67 and induces apoptosis in non-small cell lung cancer
Q35325144Thyroid transcription factor-1 (TTF-1) gene: identification of ZBP-89, Sp1, and TTF-1 sites in the promoter and regulation by TNF-α in lung epithelial cells
Q64938110Thyroid transcription factor-1 as a prognostic indicator for stage IV lung adenocarcinoma with and without EGFR-sensitizing mutations.
Q33873336Thyroid transcription factor-1-regulated microRNA-532-5p targets KRAS and MKL2 oncogenes and induces apoptosis in lung adenocarcinoma cells
Q35038884Thyroid-Specific Transcription Factors and Their Roles in Thyroid Cancer
Q37118065Tight junction proteins: from barrier to tumorigenesis.
Q91861384Towards quantitative and multiplexed in vivo functional cancer genomics
Q28655985Tracking genomic cancer evolution for precision medicine: the lung TRACERx study
Q28488566Transcriptome Sequencing of Tumor Subpopulations Reveals a Spectrum of Therapeutic Options for Squamous Cell Lung Cancer
Q34762165Transcriptome meta-analysis of lung cancer reveals recurrent aberrations in NRG1 and Hippo pathway genes
Q36491120Transcriptome sequencing of malignant pleural mesothelioma tumors
Q24653386Transcriptome sequencing to detect gene fusions in cancer
Q36354845Translating genomic information into clinical medicine: lung cancer as a paradigm
Q54484638Translational research and diagnostics in lung cancer
Q97538366Tumor evolution in epidermal growth factor receptor mutated non-small cell lung cancer
Q38209599Tumor protein D52 (TPD52) and cancer-oncogene understudy or understudied oncogene?
Q37960077Tumor-promoting functions of transforming growth factor-β in progression of cancer.
Q40398766Tumor-specific immune responses
Q33353558Tyrosine hydroxylase gene: another piece of the genetic puzzle of Parkinson's disease
Q43080951Tyrosine phosphatase PTPRD suppresses colon cancer cell migration in coordination with CD44.
Q22241904Update in lung cancer 2007
Q37287067Update in lung cancer 2008
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Q33688583Whole genome sequencing of matched tumor, adjacent non-tumor tissues and corresponding normal blood samples of hepatocellular carcinoma patients revealed dynamic changes of the mutations profiles during hepatocarcinogenesis
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Q37649231YEATS4 is a novel oncogene amplified in non-small cell lung cancer that regulates the p53 pathway.
Q58761037and Deleterious Mutations and Deletion Predict Bevacizumab Resistance in Metastatic Colorectal Cancer Patients
Q21134582arrayMap: a reference resource for genomic copy number imbalances in human malignancies
Q35238414cMyc is a principal upstream driver of beta-cell proliferation in rat insulinoma cell lines and is an effective mediator of human beta-cell replication.
Q37529618iCAGES: integrated CAncer GEnome Score for comprehensively prioritizing driver genes in personal cancer genomes
Q41412761miR-133b acts as a tumor suppressor and negatively regulates FGFR1 in gastric cancer
Q54385560miR-138 inhibits proliferation by targeting 3-phosphoinositide-dependent protein kinase-1 in non-small cell lung cancer cells.

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