Lung adenocarcinoma of never smokers and smokers harbor differential regions of genetic alteration and exhibit different levels of genomic instability

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Lung adenocarcinoma of never smokers and smokers harbor differential regions of genetic alteration and exhibit different levels of genomic instability is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...733003T
P356DOI10.1371/JOURNAL.PONE.0033003
P932PMC publication ID3296775
P698PubMed publication ID22412972
P5875ResearchGate publication ID221698736

P50authorEmily A VucicQ43585150
Calum E MacAulayQ63468497
P2093author name stringWei Zhang
Pei Wang
Adi F Gazdar
Ziding Feng
Rong Fu
William W Lockwood
Stephen Lam
John C English
Kelsie L Thu
Raj Chari
Wan L Lam
P2860cites workLung cancer in never smokers: clinical epidemiology and environmental risk factorsQ24598433
A small-cell lung cancer genome with complex signatures of tobacco exposureQ24600510
Characterizing the cancer genome in lung adenocarcinomaQ24649926
Global cancer statistics, 2002Q27860562
Lung cancer in never smokers: a reviewQ28287500
Genomic aberrations in lung adenocarcinoma in never smokersQ28385032
The UCSC Genome Browser database: update 2010Q29614173
Lung cancer in never smokers--a different diseaseQ29615414
Assessing the significance of chromosomal aberrations in cancer: methodology and application to gliomaQ30014823
Resolving the resolution of array CGH.Q33271882
Finding exclusively deleted or amplified genomic areas in lung adenocarcinomas using a novel chromosomal pattern analysisQ33481331
Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cellsQ33510334
FACADE: a fast and sensitive algorithm for the segmentation and calling of high resolution array CGH dataQ33605550
Integrated mutation, copy number and expression profiling in resectable non-small cell lung cancer.Q33840094
New driver mutations in non-small-cell lung cancerQ34161395
Lung cancer in never smokers: molecular profiles and therapeutic implicationsQ34177155
Chromosome aberrations in solid tumorsQ35201471
Mitochondrial DNA mutations in respiratory complex-I in never-smoker lung cancer patients contribute to lung cancer progression and associated with EGFR gene mutationQ35667130
Differential disruption of cell cycle pathways in small cell and non-small cell lung cancer.Q36614403
Smoking-related genomic signatures in non-small cell lung cancerQ37287242
An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumorsQ37294205
EGFR mutations and lung cancerQ37795807
Genomic profiles specific to patient ethnicity in lung adenocarcinomaQ39756938
Integrative genomic and gene expression analysis of chromosome 7 identified novel oncogene loci in non-small cell lung cancerQ39904378
Primary adenocarcinomas of the lung in nonsmokers show a distinct pattern of allelic imbalance.Q53388017
The genesis and evolution of high-grade serous ovarian cancerQ55053523
Chromosomal aberrations of primary lung adenocarcinomas in nonsmokersQ73031848
Chromosomal alterations in lung adenocarcinoma from smokers and nonsmokersQ73603262
Patterns of allelic loss differ in lung adenocarcinomas of smokers and nonsmokersQ78709816
P275copyright licenseCreative Commons CC0 LicenseQ6938433
P6216copyright statuscopyrighted, dedicated to the public domain by copyright holderQ88088423
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectadenocarcinomaQ356033
P304page(s)e33003
P577publication date2012-03-07
P1433published inPLOS OneQ564954
P1476titleLung adenocarcinoma of never smokers and smokers harbor differential regions of genetic alteration and exhibit different levels of genomic instability
P478volume7

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cites work (P2860)
Q57125214A network-based signature to predict the survival of non-smoking lung adenocarcinoma
Q35429274A search for novel cancer/testis antigens in lung cancer identifies VCX/Y genes, expanding the repertoire of potential immunotherapeutic targets
Q28390823An integrated inspection of the somatic mutations in a lung squamous cell carcinoma using next-generation sequencing
Q40259346Assessment of the clinical relevance of 17q25.3 copy number and three-dimensional telomere organization in non-small lung cancer patients
Q64075360Comparison of clinical characteristics and overall survival between spirometrically diagnosed chronic obstructive pulmonary disease (COPD) and non-COPD never-smoking stage I-IV non-small cell lung cancer patients
Q40675065Developmental transcription factor NFIB is a putative target of oncofetal miRNAs and is associated with tumour aggressiveness in lung adenocarcinoma
Q36741251EGFR, ALK, RET, KRAS and BRAF alterations in never-smokers with non-small cell lung cancer
Q35924241EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk
Q48240221Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing
Q51601238Gene Therapy for Lung Cancer.
Q33947935Genome-wide unmasking of epigenetically silenced genes in lung adenocarcinoma from smokers and never smokers
Q41513953Impact of smoking on outcome of resected lung adenocarcinoma
Q90715196Integrative Genomic Analyses Identifies GGA2 as a Cooperative Driver of EGFR-Mediated Lung Tumorigenesis
Q43889503Integrative analysis of genome-wide gene copy number changes and gene expression in non-small cell lung cancer.
Q38669282KRAS-Mutant Lung Cancers in the Era of Targeted Therapy
Q59791995Loss of the candidate tumor suppressor ZEB1 (TCF8, ZFHX1A) in Sézary syndrome
Q33888782Loss of tumour-specific ATM protein expression is an independent prognostic factor in early resected NSCLC.
Q34429985Lung cancer transcriptomes refined with laser capture microdissection
Q35957598Microtubule affinity-regulating kinase 2 is associated with DNA damage response and cisplatin resistance in non-small cell lung cancer.
Q26828860Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors
Q34159011Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular
Q47402801Never smokers with resected lung cancer: different demographics, similar survival
Q33649020Oncogenomic disruptions in arsenic-induced carcinogenesis
Q58804393Preface: lung cancer in never smokers
Q38993492Proportion of Never-Smoker Non-Small Cell Lung Cancer Patients at Three Diverse Institutions.
Q34436424Smoking status impacts microRNA mediated prognosis and lung adenocarcinoma biology
Q38103187The detection and implication of genome instability in cancer
Q38041993Transcriptome alterations induced by cigarette smoke
Q28388931Updates and controversies in the rapidly evolving field of lung cancer screening, early detection, and chemoprevention
Q38594037Variation in KRAS driver substitution distributions between tumor types is determined by both mutation and natural selection.
Q38113540Worldwide trend of increasing primary adenocarcinoma of the lung
Q34653749miR-146a inhibits cell growth, cell migration and induces apoptosis in non-small cell lung cancer cells

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