scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1028457185 |
P356 | DOI | 10.1038/SJ.ONC.1203847 |
P8608 | Fatcat ID | release_24dlemm6gjartgqm2vxhlr43v4 |
P3181 | OpenCitations bibliographic resource ID | 2277538 |
P698 | PubMed publication ID | 11039908 |
P5875 | ResearchGate publication ID | 12284368 |
P2093 | author name string | E Lees | |
W Seghezzi | |||
W Korver | |||
A O Walter | |||
J Sheung | |||
P2860 | cites work | Regulation of the cyclin B degradation system by an inhibitor of mitotic proteolysis | Q38612159 |
Cell cycle: checkpoint proteins and kinetochores | Q41642289 | ||
ayk1, a novel mammalian gene related to Drosophila aurora centrosome separation kinase, is specifically expressed during meiosis | Q48048486 | ||
Requirement for cAMP-PKA pathway activation by M phase-promoting factor in the transition from mitosis to interphase | Q49016602 | ||
A checkpoint on the road to cancer | Q58984637 | ||
Under arrest at atomic resolution | Q60081940 | ||
Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosophila and yeast Ipl1 | Q24321907 | ||
Inhibitory effect of okadaic acid derivatives on protein phosphatases. A study on structure-affinity relationship | Q24527865 | ||
Cdc20 associates with the kinase aurora2/Aik | Q24648501 | ||
Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase | Q27651185 | ||
Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex | Q27729793 | ||
Regulation of Saccharomyces cerevisiae kinetochores by the type 1 phosphatase Glc7p | Q27931654 | ||
The spindle checkpoint. | Q27931883 | ||
Defects in Saccharomyces cerevisiae protein phosphatase type I activate the spindle/kinetochore checkpoint | Q27933329 | ||
The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast | Q27937537 | ||
A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines | Q28239817 | ||
AIM-1: a mammalian midbody-associated protein required for cytokinesis | Q28260554 | ||
cDNA cloning, expression, subcellular localization, and chromosomal assignment of mammalian aurora homologues, aurora-related kinase (ARK) 1 and 2 | Q28265518 | ||
A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers | Q28272347 | ||
Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation | Q28285317 | ||
Polo-like kinases: a team that plays throughout mitosis | Q28292469 | ||
Protein kinase profile of sperm and eggs: cloning and characterization of two novel testis-specific protein kinases (AIE1, AIE2) related to yeast and fly chromosome segregation regulators | Q28506448 | ||
A novel mammalian, mitotic spindle-associated kinase is related to yeast and fly chromosome segregation regulators | Q28589729 | ||
Protein phosphatase type 1 in mammalian cell mitosis: chromosomal localization and involvement in mitotic exit | Q28755173 | ||
Universal control mechanism regulating onset of M-phase | Q29616481 | ||
Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles | Q29617537 | ||
The Shp-2 tyrosine phosphatase activates the Src tyrosine kinase by a non-enzymatic mechanism | Q30175786 | ||
The Aurora/Ipl1p kinase family: regulators of chromosome segregation and cytokinesis. | Q30323011 | ||
Cloning of STK13, a third human protein kinase related to Drosophila aurora and budding yeast Ipl1 that maps on chromosome 19q13.3-ter | Q31983674 | ||
Protein kinases in control of the centrosome cycle | Q33665649 | ||
Regulation of the APC and the exit from mitosis | Q33772649 | ||
The kinase Eg2 is a component of the Xenopus oocyte progesterone-activated signaling pathway | Q33889588 | ||
Polo-like kinases: positive regulators of cell division from start to finish. | Q34663706 | ||
AIR-2: An Aurora/Ipl1-related protein kinase associated with chromosomes and midbody microtubules is required for polar body extrusion and cytokinesis in Caenorhabditis elegans embryos | Q36255964 | ||
Type 1 protein phosphatase acts in opposition to IpL1 protein kinase in regulating yeast chromosome segregation | Q36657172 | ||
P433 | issue | 42 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | phosphorylation | Q242736 |
P304 | page(s) | 4906-16 | |
P577 | publication date | 2000-10-05 | |
P1433 | published in | Oncogene | Q1568657 |
P1476 | title | The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation | |
P478 | volume | 19 |
Q37371599 | A G-quadruplex stabilizer induces M-phase cell cycle arrest |
Q78954671 | A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly |
Q30502070 | A genetic screen identifies BRCA2 and PALB2 as key regulators of G2 checkpoint maintenance |
Q50861755 | A kinetic test characterizes kinase intramolecular and intermolecular autophosphorylation mechanisms. |
Q24797580 | A method for analyzing the ubiquitination and degradation of aurora-A |
Q35029166 | A non-mitotic role for Aurora kinase A as a direct activator of cell migration upon interaction with PLD, FAK and Src. |
Q73280786 | A novel mechanism for activation of the protein kinase Aurora A |
Q37296303 | A small-molecule inhibitor targeting the mitotic spindle checkpoint impairs the growth of uterine leiomyosarcoma |
Q31011135 | A translational regulator, PUM2, promotes both protein stability and kinase activity of Aurora-A |
Q40070142 | ASAP is a novel substrate of the oncogenic mitotic kinase Aurora-A: phosphorylation on Ser625 is essential to spindle formation and mitosis |
Q30433665 | Activation of Aurora-A kinase by protein phosphatase inhibitor-2, a bifunctional signaling protein |
Q28585404 | An essential role of the aPKC-Aurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamics |
Q93185770 | Antitumor profiles and cardiac electrophysiological effects of aurora kinase inhibitor ZM447439 |
Q51798018 | Antizyme1 mediates AURKAIP1-dependent degradation of Aurora-A. |
Q34026716 | Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A. |
Q47598076 | Aurora A activation in mitosis promoted by BuGZ. |
Q36352091 | Aurora A and B kinases as targets for cancer: will they be selective for tumors? |
Q36715681 | Aurora A kinase (AURKA) in normal and pathological cell division |
Q90788875 | Aurora A plays a dual role in migration and survival of human glioblastoma cells according to the CXCL12 concentration |
Q24318115 | Aurora A, centrosome structure, and the centrosome cycle |
Q34448311 | Aurora B is required for mitotic chromatin-induced phosphorylation of Op18/Stathmin |
Q30309901 | Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation |
Q27021024 | Aurora at the pole and equator: overlapping functions of Aurora kinases in the mitotic spindle |
Q37072448 | Aurora kinase A activates the vacuolar H+-ATPase (V-ATPase) in kidney carcinoma cells |
Q35327725 | Aurora kinase A controls meiosis I progression in mouse oocytes |
Q33830804 | Aurora kinase A is not involved in CPEB1 phosphorylation and cyclin B1 mRNA polyadenylation during meiotic maturation of porcine oocytes |
Q41737123 | Aurora kinase a regulates m1 macrophage polarization and plays a role in experimental autoimmune encephalomyelitis |
Q37666259 | Aurora kinase inhibitors: a new class of drugs targeting the regulatory mitotic system. |
Q37030878 | Aurora kinase inhibitors: identification and preclinical validation of their biomarkers |
Q40199075 | Aurora kinase targeted therapeutics in oncology: past, present and future |
Q38472421 | Aurora kinases orchestrate mitosis; who are the players? |
Q28118105 | Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells |
Q35022281 | Aurora-A in cell fate control |
Q35927244 | Aurora-A inhibition offers a novel therapy effective against intracranial glioblastoma. |
Q46658785 | Aurora-A kinase Ser349 phosphorylation is required during Xenopus laevis oocyte maturation |
Q28506140 | Aurora-A kinase is essential for bipolar spindle formation and early development |
Q34798251 | Aurora-A kinase-inactive mutants disrupt the interaction with Ajuba and cause defects in mitotic spindle formation and G2/M phase arrest in HeLa cells |
Q37613047 | Aurora-A kinase: a novel target both for cellular immunotherapy and molecular target therapy against human leukemia |
Q40388031 | Aurora-A site specificity: a study with synthetic peptide substrates |
Q27310808 | Aurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle Assembly |
Q28206898 | Aurora-B associated protein phosphatases as negative regulators of kinase activation |
Q35968406 | Aurora-kinase inhibitors as anticancer agents |
Q73320912 | Aurora2/BTAK/STK15 is involved in cell cycle checkpoint and cell survival of aggressive non‐Hodgkin's lymphoma |
Q40616838 | AuroraA overexpression overrides the mitotic spindle checkpoint triggered by nocodazole, a microtubule destabilizer |
Q44727121 | Autophosphorylation of a newly identified site of Aurora-B is indispensable for cytokinesis |
Q28247388 | BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition |
Q50881779 | Benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one derivatives as Aurora A kinase inhibitors: LQTA-QSAR analysis and detailed systematic validation of the developed model. |
Q35914001 | Bimodal Interaction of Mammalian Polo-Like Kinase 1 and a Centrosomal Scaffold, Cep192, in the Regulation of Bipolar Spindle Formation |
Q33531517 | Bioinformatic search of plant microtubule-and cell cycle related serine-threonine protein kinases. |
Q37736572 | Breast tumor subgroups reveal diverse clinical prognostic power |
Q53075287 | CDKN1A-mediated responsiveness of MLL-AF4-positive acute lymphoblastic leukemia to Aurora kinase-A inhibitors. |
Q28190491 | CENP-A phosphorylation by Aurora-A in prophase is required for enrichment of Aurora-B at inner centromeres and for kinetochore function |
Q44387441 | Cdc2-cyclin B triggers H3 kinase activation of Aurora-A in Xenopus oocytes |
Q35885862 | Cell and molecular biology of spindle poles and NuMA. |
Q40396015 | Characterization of plant Aurora kinases during mitosis |
Q39466789 | Computational investigation of cancer-associated molecular mechanism in Aurora A (S155R) mutation |
Q33836953 | Conditional transgenic system for mouse aurora a kinase: degradation by the ubiquitin proteasome pathway controls the level of the transgenic protein |
Q90221131 | Covalent Aurora A regulation by the metabolic integrator coenzyme A |
Q26771374 | Cross-Talk between AURKA and Plk1 in Mitotic Entry and Spindle Assembly |
Q27639665 | Crystal structure of aurora-2, an oncogenic serine/threonine kinase |
Q92315092 | Cyanidioschyzon merolae aurora kinase phosphorylates evolutionarily conserved sites on its target to regulate mitochondrial division |
Q24300312 | Depletion of IK causes mitotic arrest through aberrant regulation of mitotic kinases and phosphatases |
Q30488012 | Dietary flavonoid fisetin induces a forced exit from mitosis by targeting the mitotic spindle checkpoint |
Q36324220 | Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules. |
Q47071031 | Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis |
Q28279976 | EB1 promotes Aurora-B kinase activity through blocking its inactivation by protein phosphatase 2A |
Q84412773 | Evaluation of the cytotoxic activity of new jadomycin derivatives reveals the potential to improve its selectivity against tumor cells |
Q41994033 | Evidence for reciliation of RPE1 cells in late G1 phase, and ciliary localisation of cyclin B1. |
Q33792897 | Evidence toward a dual phosphatase mechanism that restricts Aurora A (Thr-295) phosphorylation during the early embryonic cell cycle. |
Q24682520 | Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis |
Q35123861 | Function and regulation of Aurora/Ipl1p kinase family in cell division |
Q44692651 | Human aurora-B binds to a proteasome alpha-subunit HC8 and undergoes degradation in a proteasome-dependent manner |
Q34447855 | INPP5E interacts with AURKA, linking phosphoinositide signaling to primary cilium stability |
Q38630091 | Id1 overexpression induces tetraploidization and multiple abnormal mitotic phenotypes by modulating aurora A |
Q48149761 | Identification and dynamics of two classes of aurora-like kinases in Arabidopsis and other plants |
Q28215792 | Identification of Aurora kinases as RasGAP Src homology 3 domain-binding proteins |
Q77166197 | Identification of a functional destruction box in the Xenopus laevis aurora-A kinase pEg2 |
Q35787361 | Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit |
Q40571912 | Identification of novel phosphorylation sites on Xenopus laevis Aurora A and analysis of phosphopeptide enrichment by immobilized metal-affinity chromatography |
Q34386813 | Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A. |
Q40374495 | Inhibition of Aurora A in response to DNA damage |
Q38741827 | Inhibition of Polo-like kinase 1 during the DNA damage response is mediated through loss of Aurora A recruitment by Bora. |
Q60951707 | Inhibitory Effect of Synthetic Flavone Derivatives on Pan-Aurora Kinases: Induction of G2/M Cell-Cycle Arrest and Apoptosis in HCT116 Human Colon Cancer Cells |
Q27679437 | Insights into Aurora-A Kinase Activation Using Unnatural Amino Acids Incorporated by Chemical Modification |
Q90341131 | Insights into the non-mitotic functions of Aurora kinase A: more than just cell division |
Q28215986 | Interaction and feedback regulation between STK15/BTAK/Aurora-A kinase and protein phosphatase 1 through mitotic cell division cycle |
Q35005238 | KUD773, a phenylthiazole derivative, displays anticancer activity in human hormone-refractory prostate cancers through inhibition of tubulin polymerization and anti-Aurora A activity. |
Q24301118 | LATS2-Ajuba complex regulates gamma-tubulin recruitment to centrosomes and spindle organization during mitosis |
Q37458626 | MET inhibition overcomes radiation resistance of glioblastoma stem-like cells |
Q39137312 | Mechanisms for nonmitotic activation of Aurora-A at cilia. |
Q34282234 | Microtubule-targeted anticancer agents and apoptosis |
Q27683971 | Molecular mechanism of Aurora A kinase autophosphorylation and its allosteric activation by TPX2 |
Q28587157 | NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment |
Q26752389 | Non-centrosomal TPX2-Dependent Regulation of the Aurora A Kinase: Functional Implications for Healthy and Pathological Cell Division |
Q34083310 | Novel 9'-substituted-noscapines: synthesis with Suzuki cross-coupling, structure elucidation and biological evaluation |
Q54977862 | Novel localization of Aurora A kinase in mouse testis suggests multiple roles in spermatogenesis. |
Q45717413 | Novel pyrimidine-2,4-diamine derivative suppresses the cell viability and spindle assembly checkpoint activity by targeting Aurora kinases |
Q48126977 | Nuclear envelope breakdown may deliver an inhibitor of protein phosphatase 1 which triggers cyclin B translation in starfish oocytes |
Q37189439 | O-linked N-acetylglucosamine cycling regulates mitotic spindle organization |
Q34818218 | On the role of aurora-A in centrosome function |
Q38223676 | Pathways for genome integrity in G2 phase of the cell cycle |
Q64245408 | Phosphatases in Mitosis: Roles and Regulation |
Q79755823 | Phospho-regulation of human protein kinase Aurora-A: analysis using anti-phospho-Thr288 monoclonal antibodies |
Q27931713 | Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p |
Q41845102 | Phosphorylation is required for PMA- and cell-cycle-induced degradation of protein kinase Cdelta. |
Q30434079 | Phosphorylation of the par polarity complex protein Par3 at serine 962 is mediated by aurora a and regulates its function in neuronal polarity |
Q39956375 | Pituitary tumor transforming gene 1 regulates Aurora kinase A activity |
Q40666306 | Preparation and characterization of a human aurora-A kinase monoclonal antibody |
Q35125439 | Progesterone and insulin stimulation of CPEB-dependent polyadenylation is regulated by Aurora A and glycogen synthase kinase-3. |
Q24321572 | Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2 |
Q24337213 | Protein phosphorylation profiling using an in situ proximity ligation assay: phosphorylation of AURKA-elicited EGFR-Thr654 and EGFR-Ser1046 in lung cancer cells |
Q47564376 | RASSF1A interacts with and activates the mitotic kinase Aurora-A. |
Q60017621 | Ran modulates spindle assembly by regulating a subset of TPX2 and Kid activities including Aurora A activation |
Q28505990 | Regulated CPEB phosphorylation during meiotic progression suggests a mechanism for temporal control of maternal mRNA translation |
Q35591745 | Regulation of Aurora-A kinase on the mitotic spindle |
Q60017623 | Regulation ofXenopusAurora A Activation by TPX2 |
Q35879819 | Relationship of increased aurora kinase A gene copy number, prognosis and response to chemotherapy in patients with metastatic colorectal cancer |
Q51036906 | Roles of aurora-A kinase in mitotic entry and G2 checkpoint in mammalian cells. |
Q35133478 | SP600125 suppresses Cdk1 and induces endoreplication directly from G2 phase, independent of JNK inhibition |
Q54336316 | Simultaneous assessment of kinetic, site-specific, and structural aspects of enzymatic protein phosphorylation. |
Q24298490 | Structural basis of Aurora-A activation by TPX2 at the mitotic spindle |
Q27640105 | Structures of the cancer-related Aurora-A, FAK, and EphA2 protein kinases from nanovolume crystallography |
Q34831438 | Suppression of p160ROCK bypasses cell cycle arrest after Aurora-A/STK15 depletion |
Q38189984 | TPX2: of spindle assembly, DNA damage response, and cancer |
Q52639097 | Targeting cell cycle kinases and kinesins in anticancer drug development. |
Q38756932 | The Aurora kinase inhibitors in cancer research and therapy |
Q42162215 | The CUL3-KLHL18 ligase regulates mitotic entry and ubiquitylates Aurora-A. |
Q27320051 | The Functional Significance of Posttranslational Modifications on Polo-Like Kinase 1 Revealed by Chemical Genetic Complementation |
Q24515254 | The Schizosaccharomyces pombe aurora-related kinase Ark1 interacts with the inner centromere protein Pic1 and mediates chromosome segregation and cytokinesis |
Q27851718 | The aurora kinase A inhibitor MLN8237 enhances cisplatin-induced cell death in esophageal adenocarcinoma cells |
Q34203062 | The aurora kinases in cell cycle and leukemia |
Q29617749 | The cellular geography of aurora kinases |
Q24540283 | The centrosomal kinase Aurora-A/STK15 interacts with a putative tumor suppressor NM23-H1. |
Q35885867 | The centrosome in higher organisms: structure, composition, and duplication |
Q24315132 | The decision to enter mitosis: feedback and redundancy in the mitotic entry network |
Q34121234 | The flavonoid eupatorin inactivates the mitotic checkpoint leading to polyploidy and apoptosis. |
Q34221736 | The tumor suppressive role of NUMB isoform 1 in esophageal squamous cell carcinoma. |
Q39647543 | Tousled-mediated activation of Aurora B kinase does not require Tousled kinase activity in vivo. |
Q36268536 | Transcriptomic characterization of fibrolamellar hepatocellular carcinoma |
Q35925301 | Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells. |
Q39219725 | Two newly identified sites in the N-terminal regulatory domain of Aurora-A are essential for auto-inhibition |
Q28242189 | p21-activated kinases in cancer |
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