Langerin/CD207 Sheds Light on Formation of Birbeck Granules and Their Possible Function in Langerhans Cells

scientific article published on January 1, 2003

Langerin/CD207 Sheds Light on Formation of Birbeck Granules and Their Possible Function in Langerhans Cells is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1002397731
P356DOI10.1385/IR:28:2:93
P953full work available at URLhttp://www.springerlink.com/index/pdf/10.1385/IR:28:2:93
P698PubMed publication ID14610287

P50authorColette Dezutter-DambuyantQ57457668
P2093author name stringJenny Valladeau
Sem Saeland
P2860cites workLangerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granulesQ22011207
Birbeck granules are subdomains of endosomal recycling compartment in human epidermal Langerhans cells, which form where Langerin accumulatesQ24555038
The beta 1 and beta 2 subunits of the AP complexes are the clathrin coat assembly componentsQ24564302
Human mannose-binding protein carbohydrate recognition domain trimerizes through a triple alpha-helical coiled-coilQ27729805
A structural explanation for the recognition of tyrosine-based endocytotic signalsQ27766009
DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cellsQ28138968
C-type lectin-like domainsQ28145477
Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissuesQ28214619
Identification of a ten-amino acid proline-rich SH3 binding siteQ28266446
Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptorQ29618735
Human epidermal Langerhans cells cointernalize by receptor-mediated endocytosis "nonclassical" major histocompatibility complex class I molecules (T6 antigens) and class II molecules (HLA-DR antigens)Q34048997
Cross-presentation, dendritic cells, tolerance and immunityQ34178099
C-type lectin receptors on dendritic cells and Langerhans cellsQ34575346
ATPase and morphologic changes in Langerhans cells induced by epicutaneous application of a sensitizing dose of DNFB.Q35266079
Molecular recognition of lipid antigens by T cell receptorsQ35834577
Serial reconstruction of the characteristic granule of the Langerhans cellQ36189439
Demonstration of the Langerhans granule by lanthanumQ36189768
Osmium zinc iodide reactive sites in the epidermal Langerhans cellQ36191140
Interleukin 15 skews monocyte differentiation into dendritic cells with features of Langerhans cellsQ36369467
Accumulation of immature Langerhans cells in human lymph nodes draining chronically inflamed skinQ36376581
A role for endogenous transforming growth factor beta 1 in Langerhans cell biology: the skin of transforming growth factor beta 1 null mice is devoid of epidermal Langerhans cellsQ36377496
The fine structure of the Langerhans cell granuleQ41088742
Circular and branched Birbeck granules and cytomembrane blebbing in Langerhans' cells after dithranol irritation.Q41277636
Transforming growth factor beta1, in the presence of granulocyte/macrophage colony-stimulating factor and interleukin 4, induces differentiation of human peripheral blood monocytes into dendritic Langerhans cellsQ41965708
Quantification of Birbeck's granules in human Langerhans' cellsQ42464575
Disappearance of certain acidic organelles (endosomes and Langerhans cell granules) accompanies loss of antigen processing capacity upon culture of epidermal Langerhans cellsQ42938806
Freeze-fracture of langerhans granules. A comparative studyQ44335120
New mechanism for amino acid influx into human epidermal Langerhans cells: L-dopa/proton counter-transport systemQ44713589
Plasmalemmal and subsurface complexes in human leukemic cells: membrane bonding by zipperlike junctionsQ44780213
Alpha IIB beta 3 integrin dissociation induced by EDTA results in formation of Birbeck granule-like structures in human blood plateletsQ46545881
Direct evidence for the cytomembrane derivation of Birbeck granules: the membrane-sandwich effect.Q53678484
Some new aspects of the Langerhans cell.Q53722724
Macrophages containing langerhans cell granules in normal lymph nodes of the rabbitQ54396230
Epidermal Langerhans Cells of AIDS Patients Express HIV-1 Regulatory and Structural GenesQ57826870
GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cellsQ59067424
Differentiation of Langerhans cells in Langerhans cell histiocytosisQ62658257
Occurrence of "cored tubule" in the birbeck granule-containing cells of miceQ67429573
Appearance of Birbeck granule-like structures in anti-T6 antibody-treated human epidermal Langerhans cellsQ68091415
Cytomembrane-derived Birbeck granules transport horseradish peroxidase to the endosomal compartment in the human Langerhans cellsQ68159690
The three-dimensional structure of cored tubules in the dermal Langerhans cells of miceQ68703663
Internalization by receptor-mediated endocytosis of T6 (CD1 "NA1/34") surface antigen in T6 positive human cord blood cells (Langerhans cell precursors?)Q68837113
A monoclonal antibody specifically reactive to human Langerhans cellsQ68910521
Cytomembrane-sandwiching in human epidermal Langerhans cells: a novel reaction to an irritantQ69031549
Derivation of Langerhans cell granules from cytomembraneQ69383708
[Identification by electron microscope of particles of probable viral nature in the granulomatous connections of a pulmonary histiocytosis "X"]Q69980781
Human epidermal Langerhans cells internalize by receptor-mediated endocytosis T6 (CD1 "NA1/34") surface antigen. Birbeck granules are involved in the intracellular traffic of the T6 antigenQ70345365
Coated Langerhans cell granules in histiocytosis X cellsQ70457293
Distribution of cored tubule-containing Langerhans cells in the skin and lymph nodes of miceQ71199362
Sequential production of Birbeck granules through adsorptive pinocytosisQ71251913
Cells containing Birbeck granules (Langerhans cell granules) in the human thymusQ71633279
The monoclonal antibody DCGM4 recognizes Langerin, a protein specific of Langerhans cells, and is rapidly internalized from the cell surfaceQ73046052
CD1a molecules traffic through the early recycling endosomal pathway in human Langerhans cellsQ73569251
Human epidermal Langerhans cells lack functional mannose receptors and a fully developed endosomal/lysosomal compartment for loading of HLA class II moleculesQ74578843
Immature human dendritic cells express asialoglycoprotein receptor isoforms for efficient receptor-mediated endocytosisQ77136959
Anatomic location and T-cell stimulatory functions of mouse dendritic cell subsets defined by CD4 and CD8 expressionQ77725476
Cultured human Langerhans cells resemble lymphoid dendritic cells in phenotype and functionQ93522010
The Langerhans cell granule is an adsorptive endocytic organelleQ93576759
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectimmunologyQ101929
P304page(s)93-107
P577publication date2003-01-01
P1433published inImmunologic ResearchQ15754981
P1476titleLangerin/CD207 sheds light on formation of birbeck granules and their possible function in Langerhans cells
Langerin/CD207 Sheds Light on Formation of Birbeck Granules and Their Possible Function in Langerhans Cells
P478volume28

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cites work (P2860)
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Q37748449Dendritic cells and their role in atherogenesis
Q24558690Disruption of the langerin/CD207 gene abolishes Birbeck granules without a marked loss of Langerhans cell function
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