Dendritic cells and T cells in the regulation of cutaneous immunity

scientific article published on January 2007

Dendritic cells and T cells in the regulation of cutaneous immunity is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/J.YADR.2007.07.014
P698PubMed publication ID18159907

P50authorKarin LoserQ88870845
P2093author name stringStefan Beissert
Karin Loser
P2860cites workLangerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granulesQ22011207
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouseQ24290693
Langerin is a natural barrier to HIV-1 transmission by Langerhans cellsQ24298848
Development and function of T cells in mice rendered interleukin-2 deficient by gene targetingQ24318910
Disruption of the langerin/CD207 gene abolishes Birbeck granules without a marked loss of Langerhans cell functionQ24558690
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3Q24672849
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammationQ24676080
Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activationQ24677534
Control of regulatory T cell development by the transcription factor Foxp3Q27860489
Foxp3 programs the development and function of CD4+CD25+ regulatory T cellsQ27860714
Langerin/CD207 Sheds Light on Formation of Birbeck Granules and Their Possible Function in Langerhans CellsQ28183293
Regulation of cutaneous malignancy by gammadelta T cellsQ28188439
DC-SIGN: escape mechanism for pathogensQ28204447
IL-15 is expressed by dendritic cells in response to type I IFN, double-stranded RNA, or lipopolysaccharide and promotes dendritic cell activationQ28207915
Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissuesQ28214619
The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cellsQ28257250
Immunosurveillance and immunoregulation by gammadelta T cellsQ28292156
Langerhans cells arise from monocytes in vivoQ28294423
The amount of scurfin protein determines peripheral T cell number and responsivenessQ28504592
Identification and expression of mouse Langerin (CD207) in dendritic cellsQ28507435
Regulatory T cell lineage specification by the forkhead transcription factor foxp3Q28510328
Survival adjustment of mature dendritic cells by IL-15.Q28510429
A function for interleukin 2 in Foxp3-expressing regulatory T cellsQ28590646
Ulcerative colitis-like disease in mice with a disrupted interleukin-2 geneQ28593669
An autoimmune disease-associated CTLA-4 splice variant lacking the B7 binding domain signals negatively in T cellsQ28610420
Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responsesQ28616569
An essential role for Scurfin in CD4+CD25+ T regulatory cellsQ29618395
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitisQ29619339
Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic miceQ30498716
An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammationQ33876035
Dysfunctional blood and target tissue CD4+CD25high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferationQ33993967
{gamma}{delta} T cell homeostasis is established in competition with {alpha}{beta} T cells and NK cellsQ34055649
Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-toleranceQ34111451
CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptorQ34116317
Epidermal viral immunity induced by CD8alpha+ dendritic cells but not by Langerhans cellsQ34265522
Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosisQ34311395
Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanismQ34392100
Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.Q34509694
Identification of regulatory T cells in tolerated allograftsQ34524237
Interleukin 2 signaling is required for CD4(+) regulatory T cell functionQ34527240
G protein-coupled receptor 83 overexpression in naive CD4+CD25- T cells leads to the induction of Foxp3+ regulatory T cells in vivoQ34540026
TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cellsQ34556464
C-type lectin receptors on dendritic cells and Langerhans cellsQ34575346
Langerhans cells - dendritic cells of the epidermis.Q35219303
The role of the combination of IL-2 and TGF-β or IL-10 in the generation and function of CD4+ CD25+ and CD8+regulatory T cell subsetsQ35547512
Activated CD4+CD25+ T cells selectively kill B lymphocytesQ35848308
GITR: a multifaceted regulator of immunity belonging to the tumor necrosis factor receptor superfamilyQ36072196
Mechanisms of suppression by suppressor T cellsQ36078047
Cutaneous dendritic cellsQ36161713
Identification of a radio-resistant and cycling dermal dendritic cell population in mice and men.Q36228168
The integration of conventional and unconventional T cells that characterizes cell-mediated responsesQ36231104
Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivityQ36321301
Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitroQ36349915
Presentation of exogenous protein antigens by dendritic cells to T cell clones. Intact protein is presented best by immature, epidermal Langerhans cellsQ36356239
Resident skin-specific gammadelta T cells provide local, nonredundant regulation of cutaneous inflammationQ36370190
Vaginal submucosal dendritic cells, but not Langerhans cells, induce protective Th1 responses to herpes simplex virus-2Q36370493
Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cellsQ36371345
Gamma delta T cells provide an early source of interferon gamma in tumor immunityQ36371404
The distinct contributions of murine T cell receptor (TCR)gammadelta+ and TCRalphabeta+ T cells to different stages of chemically induced skin cancerQ36371644
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetesQ36399048
CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes.Q36399104
Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumorsQ36402716
EXCEPTIONAL INHERITANCE OF A SEX-LINKED GENE IN THE MOUSE EXPLAINED ON THE BASIS THAT THE X/O SEX-CHROMOSOME CONSTITUTION IS FEMALEQ36428216
Langerhans cells renew in the skin throughout life under steady-state conditionsQ36505129
Therapeutic modulation of cutaneous autoimmunity by regulatory T cellsQ36599177
CD4+CD25bright regulatory T cells actively regulate inflammation in the joints of patients with the remitting form of juvenile idiopathic arthritis.Q47643874
The effects of interleukin-15 on human gammadelta T cell responses to Plasmodium falciparum in vitroQ47841596
IL-1beta-induced Langerhans' cell migration and TNF-alpha production in human skin: regulation by lactoferrinQ47969493
Relation of CD4+CD25+ regulatory T-cell suppression of allergen-driven T-cell activation to atopic status and expression of allergic diseaseQ48029520
Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells.Q50768287
Decreased CD4+CD25+ T cells in peripheral blood of patients with systemic lupus erythematosus.Q51052689
Telomere length of in vivo expanded CD4(+)CD25 (+) regulatory T-cells is preserved in cancer patients.Q53351188
Ueber die Nerven der menschlichen HautQ54268491
Activation requirements for the induction of CD4+CD25+ T cell suppressor functionQ56903555
Induction of CD4+/CD25+ regulatory T cells by targeting of antigens to immature dendritic cellsQ56903879
Heavy chain ferritin activates regulatory T cells by induction of changes in dendritic cellsQ56904454
Induction of T-cell-mediated skin disease specific for antigen transgenically expressed in keratinocytesQ57174480
Epidermal RANKL controls regulatory T-cell numbers via activation of dendritic cellsQ57184743
Cutting Edge: TGF- Signaling Is Required for the In Vivo Expansion and Immunosuppressive Capacity of Regulatory CD4+CD25+ T CellsQ58131166
Epidermal Langerhans cells bear Fc and C3 receptorsQ59049033
Langerhans Cells Activate Naive Self-Antigen-Specific CD8 T Cells in the Steady StateQ60181710
Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell levelQ60311694
Langerhans Cell Function Dictates Induction of Contact Hypersensitivity or Unresponsiveness to DNFB in Syrian HamstersQ70877425
Tumour necrosis factor receptor II (p75) signalling is required for the migration of Langerhans' cellsQ71216216
Adhesion molecule expression by epidermal Langerhans cells and lymph node dendritic cells: a comparisonQ71848351
Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor betaQ72287439
The monoclonal antibody DCGM4 recognizes Langerin, a protein specific of Langerhans cells, and is rapidly internalized from the cell surfaceQ73046052
Increased T cell autoreactivity in the absence of CD40-CD40 ligand interactions: a role of CD40 in regulatory T cell developmentQ73311881
Interleukin 1 beta and the stimulation of Langerhans cell migration: comparisons with tumour necrosis factor alphaQ73369495
The TCR-delta repertoire in normal human skin is restricted and distinct from the TCR-delta repertoire in the peripheral bloodQ73443686
Evidence for a novel function of the CD40 ligand as a signalling molecule in T-lymphocytesQ73966934
Langerhans cells require signals from both tumour necrosis factor-alpha and interleukin-1 beta for migrationQ74254654
Immature human dendritic cells express asialoglycoprotein receptor isoforms for efficient receptor-mediated endocytosisQ77136959
Dermal-resident CD14+ cells differentiate into Langerhans cellsQ77149823
Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signalsQ77704341
Langerhans cell migration in mice requires intact type I interleukin 1 receptor (IL-1RI) functionQ78043610
Tumour necrosis factor-alpha induces Langerhans cell migration in humansQ78196282
Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbersQ78404451
The fine structure of the melanocyte and melanin granuleQ79118683
Identification of lesional CD4+ CD25+ Foxp3+ regulatory T cells in PsoriasisQ80093849
CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditionsQ80444912
Turnover of epidermal Langerhans' cellsQ81152740
Cutaneous CXCL14 targets blood precursors to epidermal niches for Langerhans cell differentiationQ81230336
Homing and function of human skin gammadelta T cells and NK cells: relevance for tumor surveillanceQ82878964
Control of autoimmune myocarditis and multiorgan inflammation by glucocorticoid-induced TNF receptor family-related protein(high), Foxp3-expressing CD25+ and CD25- regulatory T cellsQ83059351
Characteristics of CD4+CD25+ regulatory T cells in the peripheral circulation of patients with head and neck cancerQ36616391
Biology of Langerhans cells: selective migration of Langerhans cells into allogeneic and xenogeneic grafts on nude miceQ37606634
Epidermal langerhans cell-deficient mice develop enhanced contact hypersensitivityQ38317679
Antigen-presenting cells in the induction of contact hypersensitivity in mice: evidence that Langerhans cells are sufficient but not requiredQ38516917
Localization of antigen on lymph node dendritic cells after exposure to the contact sensitizer fluorescein isothiocyanate. Functional and morphological studiesQ38518849
An important role of CD80/CD86-CTLA-4 signaling during photocarcinogenesis in miceQ40432672
Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cellsQ40498116
Neuropilin-1: a surface marker of regulatory T cellsQ40584286
Visualization and characterization of migratory Langerhans cells in murine skin and lymph nodes by antibodies against Langerin/CD207.Q40675455
Ia antigen expression on human epidermal Langerhans cellsQ40792234
Epidermal Langerhans cells express Ia antigensQ40792241
The fine structure of the Langerhans cell granuleQ41088742
Adhesion of epidermal Langerhans cells to keratinocytes mediated by E-cadherinQ41578917
Depletion of epidermal langerhans cells and Ia immunogenicity from tape-stripped mouse skinQ41808649
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive stateQ42466421
Overexpression of CD40 ligand in murine epidermis results in chronic skin inflammation and systemic autoimmunityQ42509581
Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cellsQ42944333
Autocrine/paracrine IL-15 that is required for type I IFN-mediated dendritic cell expression of MHC class I-related chain A and B is impaired in hepatitis C virus infectionQ42981145
Epidermal Langerhans cells are derived from cells originating in bone marrowQ44522186
CD8 alpha- and Langerin-negative dendritic cells, but not Langerhans cells, act as principal antigen-presenting cells in leishmaniasis.Q44910134
Defective suppression of Th2 cytokines by CD4CD25 regulatory T cells in birch allergics during birch pollen seasonQ45043921
In vitro-generated regulatory T cells induced by Foxp3-retrovirus infection control murine contact allergy and systemic autoimmunityQ45884432
Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokinesQ45889051
Generation ex vivo of TGF-beta-producing regulatory T cells from CD4+CD25- precursors.Q45972944
Cutting Edge: CD28 Controls Peripheral Homeostasis of CD4+CD25+ Regulatory T CellsQ46025217
Distinct roles of CTLA-4 and TGF-beta in CD4+CD25+ regulatory T cell functionQ46468450
IL-12 breaks dinitrothiocyanobenzene (DNTB)-mediated tolerance and converts the tolerogen DNTB into an immunogenQ46763995
FK506 controls CD40L-induced systemic autoimmunity in miceQ46937604
Enhanced contact hypersensitivity and antiviral immune responses in vivo by keratinocyte-targeted overexpression of IL-15.Q47299543
Induction of GVHD-like skin disease by passively transferred CD8(+) T-cell receptor transgenic T cells into keratin 14-ovalbumin transgenic miceQ47361035
Type I regulatory T cells specific for desmoglein 3 are more frequently detected in healthy individuals than in patients with pemphigus vulgarisQ47643831
P921main subjectdendritic cellQ506253
P304page(s)307-333
P577publication date2007-01-01
P1433published inAdvances in dermatologyQ26839851
P1476titleDendritic cells and T cells in the regulation of cutaneous immunity
P478volume23

Reverse relations

cites work (P2860)
Q37090131Antagonism of CRTH2 ameliorates chronic epicutaneous sensitization-induced inflammation by multiple mechanisms
Q35798899Cervical (pre)neoplastic microenvironment promotes the emergence of tolerogenic dendritic cells via RANKL secretion
Q38569504Chemical allergy: translating biology into hazard characterization
Q47711199Chemokine receptors in T-cell-mediated diseases of the skin
Q51566897Cottontail rabbit papillomavirus in Langerhans cells in Sylvilagus spp.
Q38154918Cytokines as biomarkers in depressive disorder: current standing and prospects.
Q42017216Gingiva Equivalents Secrete Negligible Amounts of Key Chemokines Involved in Langerhans Cell Migration Compared to Skin Equivalents
Q35606553Helminth Infection and Commensal Microbiota Drive Early IL-10 Production in the Skin by CD4+ T Cells That Are Functionally Suppressive
Q40098383Host immune responses to the itch mite, Sarcoptes scabiei, in humans
Q84991259Immunosuppressive Effect of Cordyceps CS-4 on Human Monocyte-Derived Dendritic Cellsin Vitro
Q37191348Langerhans cell deficiency impairs Ixodes scapularis suppression of Th1 responses in mice
Q35894485Langerhans cell precursors acquire RANK/CD265 in prenatal human skin
Q23919296Physical-chemical and solvent considerations in evaluating the influence of carbon chain length on the skin sensitization activity of 1-bromoalkanes
Q33880072Proliferative and non-proliferative lesions of the rat and mouse integument.
Q42453848Skin-specific promoters for genetic immunisation by DNA electroporation
Q34235746The role of the IL-12 cytokine family in directing T-cell responses in oral candidosis.
Q37743180Viruses and Langerhans cells
Q37460941What determines the success or failure of intracellular cutaneous parasites? Lessons learned from leishmaniasis