scholarly article | Q13442814 |
P2093 | author name string | Itoh M | |
Sakaguchi S | |||
Takahashi T | |||
Shimizu J | |||
Sakaguchi N | |||
Toda M | |||
Iwata M | |||
Kuniyasu Y | |||
P433 | issue | 12 | |
P921 | main subject | autoimmune disease | Q8084905 |
P304 | page(s) | 1969-1980 | |
P577 | publication date | 1998-12-01 | |
P1433 | published in | International Immunology | Q15710043 |
P1476 | title | Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state | |
P478 | volume | 10 |
Q35980876 | 4-1BB Signaling in Conventional T Cells Drives IL-2 Production That Overcomes CD4+CD25+FoxP3+ T Regulatory Cell Suppression |
Q41891740 | A Novel mTORC1-Dependent, Akt-Independent Pathway Differentiates the Gut Tropism of Regulatory and Conventional CD4 T Cells. |
Q35757103 | A Short Peptide That Mimics the Binding Domain of TGF-β1 Presents Potent Anti-Inflammatory Activity |
Q35143924 | A dual altered peptide ligand down-regulates myasthenogenic T cell responses by up-regulating CD25- and CTLA-4-expressing CD4+T cells |
Q42841189 | A genetically selective inhibitor demonstrates a function for the kinase Zap70 in regulatory T cells independent of its catalytic activity |
Q24793306 | A paragon of self-tolerance: CD25+CD4+ regulatory T cells and the control of immune responses |
Q34171642 | A pivotal role of vitamin B9 in the maintenance of regulatory T cells in vitro and in vivo |
Q36721781 | A potential role for estrogen in experimental autoimmune encephalomyelitis and multiple sclerosis |
Q36389642 | A simple mechanistic explanation for original antigenic sin and its alleviation by adjuvants |
Q39887068 | A specific CD4 epitope bound by tregalizumab mediates activation of regulatory T cells by a unique signaling pathway |
Q36078042 | A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3. |
Q35172102 | About CD4pos CD25pos regulatory cells |
Q35175974 | Absence of β2 integrins impairs regulatory T cells and exacerbates CD4+ T cell-dependent autoimmune carditis |
Q36379628 | Accumulation Mechanisms of CD4(+)CD25(+)FOXP3(+) Regulatory T Cells in EBV-associated Gastric Carcinoma |
Q39654917 | Accumulation of human heat shock protein 60-reactive T cells in the gingival tissues of periodontitis patients |
Q33337399 | Achieving optimal outcomes in chronic lymphocytic leukaemia |
Q53671743 | Activated CD4+ CD25+ T cells suppress antigen-specific CD4+ and CD8+ T cells but induce a suppressive phenotype only in CD4+ T cells. |
Q79415991 | Activation of CD4+ CD25+ regulatory T cell suppressor function by analogs of the selecting peptide |
Q36002606 | Activation of naturally occurring lung CD4(+)CD25(+) regulatory T cells requires CD8 and MHC I interaction |
Q37818449 | Adaptive T-cell responses regulating oral tolerance to protein antigen |
Q35753012 | Administration of the stress protein gp96 prolongs rat cardiac allograft survival, modifies rejection-associated inflammatory events, and induces a state of peripheral T-cell hyporesponsiveness |
Q37419201 | Adoptive therapy with redirected primary regulatory T cells results in antigen-specific suppression of arthritis |
Q36988746 | Advancements in immune tolerance |
Q56901055 | Age-related changes in the occurrence and characteristics of thymic CD4(+) CD25(+) T cells in mice |
Q34580976 | All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation |
Q83485975 | Allogeneic apoptotic thymocyte-stimulated dendritic cells expand functional regulatory T cells |
Q78008037 | An established immune response against ovalbumin is suppressed by a transferable serum factor produced after ovalbumin feeding: a role of CD25+ regulatory cells |
Q43636357 | An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection. |
Q54608720 | An inverse correlation of human peripheral blood regulatory T cell frequency with the disease activity of ulcerative colitis. |
Q37729684 | An isoleucine-zipper motif enhances costimulation of human soluble trimeric GITR ligand. |
Q42427913 | An optimized multi-parameter flow cytometry protocol for human T regulatory cell analysis on fresh and viably frozen cells, correlation with epigenetic analysis, and comparison of cord and adult blood. |
Q34374544 | An overview of regulatory T cells |
Q34604727 | Analysis of adhesion molecules, target cells, and role of IL-2 in human FOXP3+ regulatory T cell suppressor function |
Q33958418 | Anergic T cells as active regulators of the immune response |
Q34096254 | Animal models of autoimmunity and their relevance to human diseases |
Q34975035 | Anti-CD25 antibody treatment of mice vaccinated and challenged with Borrelia spp. does not exacerbate arthritis but inhibits borreliacidal antibody production |
Q84459533 | Anti-PD-1 synergizes with cyclophosphamide to induce potent anti-tumor vaccine effects through novel mechanisms |
Q27000514 | Antibody-based immunotherapy for ovarian cancer: where are we at? |
Q35755287 | Antigen specificity and T-cell clonality in periodontal disease |
Q36371283 | Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo |
Q53663389 | Antigen-dependent suppression of alloresponses by Foxp3-induced regulatory T cells in transplantation. |
Q42126452 | Antigen-induced IL-10+ regulatory T cells are independent of CD25+ regulatory cells for their growth, differentiation, and function |
Q35092544 | Antigen-induced regulatory T cells in autoimmunity |
Q51889416 | Antigen-specific Treg impair CD8(+) T-cell priming by blocking early T-cell expansion. |
Q47239334 | Antigen-specific in vitro suppression of murine Helicobacter pylori-reactive immunopathological T cells by CD4CD25 regulatory T cells |
Q37381562 | Antigen-specific induced T regulatory cells impair dendritic cell function via an IL-10/MARCH1-dependent mechanism |
Q37270469 | Apoptosis as a mechanism of T-regulatory cell homeostasis and suppression |
Q33786819 | Apoptosis of purified CD4+ T cell subsets is dominated by cytokine deprivation and absence of other cells in new onset diabetic NOD mice |
Q37742101 | Approaches for immunological tolerance induction to stem cell-derived cell replacement therapies |
Q82249664 | Assay of T- and NK-cell subsets and the expression of NKG2A and NKG2D in patients with new-onset systemic lupus erythematosus |
Q37274087 | Assessment of regulatory T-cell function in forthcoming clinical trials of cell therapy. |
Q37595104 | Association of CD4+ CD25+ T cells with prevention of severe destructive arthritis in Borrelia burgdorferi-vaccinated and challenged gamma interferon-deficient mice treated with anti-interleukin-17 antibody |
Q41926669 | Association of two clones allows for optimal detection of human FOXP3. |
Q36979743 | Autoantibody production in lpr/lpr gld/gld mice reflects accumulation of CD4+ effector cells that are resistant to regulatory T cell activity |
Q35573371 | Autoimmune Diseases as the Loss of Active “Self‐Control” |
Q36522843 | Autoimmunity: basic mechanisms and implications in endocrine diseases. Part II. |
Q28204573 | B cells and professional APCs recruit regulatory T cells via CCL4 |
Q42502298 | B-cell-delivered gene therapy induces functional T regulatory cells and leads to a loss of antigen-specific effector cells |
Q82266368 | B7-1 and B7-2 differentially control peripheral homeostasis of CD4(+)CD25(+)Foxp3(+) regulatory T cells |
Q36595842 | BRG1-mediated immune tolerance: facilitation of Treg activation and partial independence of chromatin remodelling |
Q34079330 | Bacterial vaccines for the treatment of multiple sclerosis and other autoimmune disorders |
Q36791858 | Biphasic regulation of Il2 transcription in CD4+ T cells: roles for TNF-alpha receptor signaling and chromatin structure |
Q56903050 | Blockade of CD86 signaling facilitates a Th2 bias at the maternal-fetal interface and expands peripheral CD4+CD25+ regulatory T cells to rescue abortion-prone fetuses |
Q36107928 | Blockade of TNF-α signaling benefits cancer therapy by suppressing effector regulatory T cell expansion |
Q38020477 | Boosting regulatory T cell function by CD4 stimulation enters the clinic |
Q26744624 | Breaking Free of Control: How Conventional T Cells Overcome Regulatory T Cell Suppression |
Q29618394 | CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells |
Q35318823 | CD154 is a negative regulator of autoaggressive CD8+ T cells in type 1 diabetes |
Q36399104 | CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes. |
Q36232697 | CD25+ CD4+ regulatory T-cells in cancer |
Q37366174 | CD25+ T cells induce Helicobacter pylori-specific CD25- T-cell anergy but are not required to maintain persistent hyporesponsiveness |
Q83160035 | CD25+ T(reg) specifically suppress auto-Ab generation against pancreatic tissue autoantigens |
Q35044776 | CD25+ regulatory T cells and tumor immunity |
Q28215020 | CD28 function: a balance of costimulatory and regulatory signals |
Q87486130 | CD28 signals the differential control of regulatory T cells and effector T cells |
Q40730152 | CD39 and control of cellular immune responses |
Q42575046 | CD4(+) CD25(+) FoxP3(+) regulatory T cells suppress cytotoxicity of CD8(+) effector T cells: implications for their capacity to limit inflammatory central nervous system damage at the parenchymal level. |
Q34418015 | CD4(+) regulatory T cells |
Q34987296 | CD4(+) regulatory T cells in autoimmunity and allergy |
Q44786390 | CD4(+)CD25 (+)CD127 (low/-) T cells: a more specific Treg population in human peripheral blood |
Q36369151 | CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade |
Q34525987 | CD4(+)CD25(+) immunoregulatory T Cells: new therapeutics for graft-versus-host disease |
Q34116317 | CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor |
Q36370807 | CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness |
Q53666742 | CD4+ CD25+ FOXP3+ regulatory T cells from human thymus and cord blood suppress antigen-specific T cell responses. |
Q35694441 | CD4+ CD25+ Treg: divide and rule? |
Q34681157 | CD4+ CD25+ regulatory T cells modulate the T-cell and antibody responses in helicobacter-infected BALB/c mice |
Q34716304 | CD4+ CD25+ suppressor T cells: more questions than answers |
Q50784115 | CD4+ Foxp3+ regulatory T cells in autoimmune orchitis: phenotypic and functional characterization. |
Q78766784 | CD4+ T regulatory cells from the colonic lamina propria of normal mice inhibit proliferation of enterobacteria-reactive, disease-inducing Th1-cells from scid mice with colitis |
Q35936484 | CD4+ Tregs and immune control |
Q37106789 | CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance |
Q36251271 | CD4+ regulatory cells as a potential immunotherapy |
Q40624661 | CD4+CD25+ T Cells Lyse Antigen-Presenting B Cells by Fas-Fas Ligand Interaction in an Epitope-Specific Manner |
Q24673863 | CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms |
Q24804208 | CD4+CD25+ immunoregulatory T cells may not be involved in controlling autoimmune arthritis |
Q44643759 | CD4+CD25+ regulatory T cells generated in response to insulin B:9-23 peptide prevent adoptive transfer of diabetes by diabetogenic T cells. |
Q53517484 | CD4+CD25+ regulatory T cells have divergent effects on intestinal inflammation in IL-10 gene-deficient mice. |
Q37905796 | CD4+CD25+ regulatory T cells in systemic sclerosis and other rheumatic diseases |
Q34161141 | CD4+CD25+ regulatory T cells limit the risk of autoimmune disease arising from T cell receptor crossreactivity |
Q33614706 | CD4+CD25+ regulatory T cells restrain pathogenic responses during Leishmania amazonensis infection |
Q84348158 | CD4+CD25+ regulatory T cells suppress Th17-responses in an experimental colitis model |
Q40397533 | CD4+CD25+ regulatory T-cell lines from human cord blood have functional and molecular properties of T-cell anergy |
Q36223583 | CD4+CD25+-regulatory T cells from mouse to man. |
Q34709777 | CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells |
Q36978507 | CD4+CD25high T cell numbers are enriched in the peripheral blood of patients with rheumatoid arthritis. |
Q51041309 | CD4+CD25high regulatory T cells are markedly decreased in blood of patients with pemphigus vulgaris. |
Q92538754 | CD4+FOXP3+ Regulatory T Cell Therapies in HLA Haploidentical Hematopoietic Transplantation |
Q47692038 | CD8+CD122+ regulatory T cells recognize activated T cells via conventional MHC class I-alphabetaTCR interaction and become IL-10-producing active regulatory cells. |
Q35912427 | CD98 at the crossroads of adaptive immunity and cancer |
Q37765583 | Can vaccination or tyrosine kinase inhibitor therapy play a role in the adjuvant treatment of renal cell carcinoma? |
Q93048216 | Cancer Immunotherapies Targeting Tumor-Associated Regulatory T Cells |
Q34517421 | Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta |
Q26999223 | Cell death in the maintenance and abrogation of tolerance: the five Ws of dying cells |
Q36369181 | Certified professionals: CD4(+)CD25(+) suppressor T cells |
Q34374565 | Characterisation of thymus-derived regulatory T cells that protect against organ-specific autoimmune disease |
Q56902065 | Characteristics of rat CD4(+)CD25(+) T cells and their ability to prevent not only diabetes but also insulitis in an adoptive transfer model in BB rats |
Q45031474 | Characterization of mouse CD4 T cell subsets defined by expression of KLRG1. |
Q48440316 | Chemokine receptors associated with immunity within and outside the central nervous system in early relapsing-remitting multiple sclerosis |
Q64974096 | Chimeric antigen receptor costimulation domains modulate human regulatory T cell function. |
Q37486824 | Chronic follicular bronchiolitis requires antigen-specific regulatory T cell control to prevent fatal disease progression |
Q52682313 | Clinical Grade Regulatory CD4+ T Cells (Tregs): Moving Toward Cellular-Based Immunomodulatory Therapies. |
Q36150414 | Clinical application of human CD4+ CD25+ regulatory T cells for the treatment of inflammatory bowel diseases |
Q30645348 | Clinical features of idiopathic inflammatory polymyopathy in the Hungarian Vizsla |
Q54439076 | Cloning and expression of canine CD25 for validation of an anti-human CD25 antibody to compare T regulatory lymphocytes in healthy dogs and dogs with osteosarcoma. |
Q36403785 | Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia |
Q36485931 | Coinhibitory T-cell signaling in islet allograft rejection and tolerance |
Q40972048 | Combination treatment with fingolimod and a pathogenic antigen prevents relapse of glucose-6-phosphate isomerase peptide-induced arthritis |
Q84300301 | Comparative analysis of dendritic cells and anti-CD3/CD28 expanded regulatory T cells for application in transplantation |
Q37001564 | Comparative assessment of the prevalence of periodontal disease in subjects with and without systemic autoimmune diseases: A case-control study |
Q36960313 | Comparative methodologies of regulatory T cell depletion in a murine melanoma model |
Q41983541 | Comparative study of regulatory T cell function of human CD25CD4 T cells from thymocytes, cord blood, and adult peripheral blood |
Q38042925 | Competition for IL-2 between Regulatory and Effector T Cells to Chisel Immune Responses |
Q36915438 | Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression |
Q36371658 | Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state. |
Q35623006 | Control of autoimmunity by naturally arising regulatory CD4+ T cells |
Q34058688 | Control of experimental inflammatory bowel disease by regulatory T cells |
Q33833208 | Control of immune pathology by IL-10-secreting regulatory T cells |
Q42944823 | Control of immune responses by naturally arising CD4+ regulatory T cells that express toll-like receptors |
Q34374586 | Control of intestinal inflammation by regulatory T cells. |
Q34374577 | Control of organ-specific autoimmunity by immunoregulatory CD4(+)CD25(+) T cells |
Q36402576 | Conversion of CD4+ CD25- cells into CD4+ CD25+ regulatory T cells in vivo requires B7 costimulation, but not the thymus |
Q40051110 | Costimulation controls diabetes by altering the balance of pathogenic and regulatory T cells. |
Q34786861 | Costimulatory signals controlling regulatory T cells |
Q42821897 | Curcumin induces maturation-arrested dendritic cells that expand regulatory T cellsin vitroandin vivo |
Q42617070 | Curing CNS autoimmune disease with myelin-reactive Foxp3+ Treg |
Q89727168 | Current advances and outlooks in immunotherapy for pancreatic ductal adenocarcinoma |
Q37349582 | Cutting edge: regulatory T cells do not require stimulation through their TCR to suppress |
Q33246674 | Cytotoxic T lymphocyte antigen-4-dependent down-modulation of costimulatory molecules on dendritic cells in CD4+ CD25+ regulatory T-cell-mediated suppression |
Q24676080 | Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation |
Q51052689 | Decreased CD4+CD25+ T cells in peripheral blood of patients with systemic lupus erythematosus. |
Q35224581 | Decreased HIV-specific T-regulatory responses are associated with effective DC-vaccine induced immunity |
Q24804229 | Defective CD4+CD25+ regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-gamma |
Q45043921 | Defective suppression of Th2 cytokines by CD4CD25 regulatory T cells in birch allergics during birch pollen season |
Q48020872 | Demonstration of strong enterobacterial reactivity of CD4+CD25- T cells from conventional and germ-free mice which is counter-regulated by CD4+CD25+ T cells |
Q37045247 | Dendritic cells and T cells in the regulation of cutaneous immunity |
Q36563563 | Dendritic cells expand antigen-specific Foxp3+ CD25+ CD4+ regulatory T cells including suppressors of alloreactivity. |
Q38117138 | Dendritic cells in the periphery control antigen-specific natural and induced regulatory T cells |
Q54518230 | Dendritic cells modulated by innate immunity improve collagen-induced arthritis and induce regulatory T cells in vivo. |
Q40678738 | Development of CD4+ T cell lines that suppress an antigen-specific immune response in vivo |
Q83153136 | Development of a capture ELISA to determine kinetics of soluble CD25 following in vitro and in vivo stimulation of duck peripheral blood monocytes |
Q36941092 | Development of regulatory T cells requires IL-7Ralpha stimulation by IL-7 or TSLP. |
Q90601927 | Differential expression of immune markers in the patients with obstructive sleep apnea/hypopnea syndrome |
Q37702018 | Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation |
Q36954436 | Differentiation of regulatory Foxp3+ T cells in the thymic cortex |
Q37733238 | Direct detection of FoxP3 expression in thymic double-negative CD4-CD8- cells by flow cytometry |
Q36371345 | Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells |
Q33713280 | Dissecting the role of CD4+ T cells in autoimmune diabetes through the use of TCR transgenic mice |
Q33742099 | Distinct IL-2 receptor signaling pattern in CD4+CD25+ regulatory T cells |
Q38299845 | Diverse mechanisms regulate the surface expression of immunotherapeutic target ctla-4. |
Q34791870 | Diversity of regulatory CD4+T cells controlling distinct organ-specific autoimmune diseases |
Q36585041 | Does our current understanding of the molecular basis of immune tolerance predict new therapies for autoimmune disease? |
Q61651663 | Dominant transplantation tolerance impairs CD8+ T cell function but not expansion |
Q35865098 | Donor-derived, tolerogenic dendritic cells suppress immune rejection in the indirect allosensitization-dominant setting of corneal transplantation |
Q36370863 | Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation |
Q36604797 | Double-negative regulatory T cells: non-conventional regulators |
Q44914986 | Dynamic regulation of FoxP3 expression controls the balance between CD4+ T cell activation and cell death |
Q33993967 | Dysfunctional blood and target tissue CD4+CD25high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferation |
Q56903755 | Early Events in Peripheral Regulatory T Cell Induction via the Nasal Mucosa |
Q36676017 | Effect of bacillus Calmette-Guérin vaccination on CD4+Foxp3+ T cells during acquired immune response to Mycobacterium tuberculosis infection |
Q54563660 | Embelin suppresses dendritic cell functions and limits autoimmune encephalomyelitis through the TGF-β/β-catenin and STAT3 signaling pathways. |
Q36486882 | Emerging possibilities in the development and function of regulatory T cells |
Q34147162 | Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells |
Q41873492 | Essential roles of CD8+CD122+ regulatory T cells in the maintenance of T cell homeostasis |
Q51629955 | Estradiol-dependent perforin expression by human regulatory T-cells. |
Q35530818 | Evaluation of immunosuppressive function of regulatory T cells using a novel in vitro cytotoxicity assay |
Q51977695 | Evidence for immunological priming and increased frequency of CD4+ CD25+ cord blood T cells in children born to mothers with type 1 diabetes. |
Q44359280 | Ex vivo analysis of pancreatic cancer-infiltrating T lymphocytes reveals that ENO-specific Tregs accumulate in tumor tissue and inhibit Th1/Th17 effector cell functions |
Q42141982 | Ex vivo expansion of tumor specific lymphocytes with IL-15 and IL-21 for adoptive immunotherapy in melanoma |
Q41973912 | Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood |
Q56903817 | Exon-1 polymorphism of ctla-4 gene in Iranian patients with Graves' disease |
Q39287039 | Expanding Diversity and Common Goal of Regulatory T and B Cells. I: Origin, Phenotype, Mechanisms |
Q54549498 | Expansion and de novo generation of potentially therapeutic regulatory T cells in patients with autoimmune hepatitis. |
Q35990538 | Expansion of CD4+CD25+ suppressive regulatory T cells from rhesus macaque peripheral blood by FN18/antihuman CD28-coated Dynal beads |
Q37712267 | Expansion of Foxp3(+) T-cell populations by Candida albicans enhances both Th17-cell responses and fungal dissemination after intravenous challenge. |
Q36069509 | Experimental autoimmune gastritis: mouse models of human organ-specific autoimmune disease. |
Q38449217 | Expression of IL-2 in β cells by AAV8 gene transfer in pre-diabetic NOD mice prevents diabetes through activation of FoxP3-positive regulatory T cells |
Q24538658 | Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells |
Q38203784 | FOXP3 and scurfy: how it all began |
Q29307487 | FOXP3+ regulatory T cells in the human immune system |
Q37937127 | FOXP3+ regulatory T cells: from suppression of rejection to induction of renal allograft tolerance |
Q37349656 | Fc receptor-like 3 protein expressed on IL-2 nonresponsive subset of human regulatory T cells |
Q82277170 | Flow cytometric analysis of expression of transforming growth factor-beta and glucocorticoid-induced tumor necrosis factor receptor on CD4(+) CD25(+) T cells of patients with inflammatory bowel disease |
Q43128400 | Forkhead box p3+ regulatory T cell underlies male resistance to experimental type 2 autoimmune hepatitis |
Q24300625 | Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1 |
Q37972689 | Foxp3(+) regulatory T cells, immune stimulation and host defence against infection |
Q33932451 | Foxp3+ CD25- CD4 T cells constitute a reservoir of committed regulatory cells that regain CD25 expression upon homeostatic expansion |
Q55391463 | Foxp3+ T Regulatory Cells: Still Many Unanswered Questions-A Perspective After 20 Years of Study. |
Q36786930 | Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation |
Q85954238 | Foxp3+ regulatory T cells are activated in spite of B7-CD28 and CD40-CD40L blockade |
Q52624752 | Foxp3-independent loss of regulatory CD4+ T-cell suppressive capacities induced by self-deprivation. |
Q35102281 | Foxp3-positive macrophages display immunosuppressive properties and promote tumor growth |
Q38170088 | Foxp3⁺ T(reg) cells in humoral immunity. |
Q35172468 | Foxp3⁺ regulatory T cells exert asymmetric control over murine helper responses by inducing Th2 cell apoptosis. |
Q36232655 | Function of tumor necrosis factor receptor family members on regulatory T-cells |
Q35830699 | Functional Modulation of Regulatory T Cells by IL-2. |
Q38457268 | Functional changes in regulatory T cells during an experimental infection with sparganum (plerocercofid of Spirometra mansoni). |
Q33987128 | Functional characterization and gene expression analysis of CD4+ CD25+ regulatory T cells generated in mice treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin |
Q38022007 | Functional crosstalk between dendritic cells and Foxp3(+) regulatory T cells in the maintenance of immune tolerance |
Q36984057 | Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation |
Q33752581 | GITR engagement preferentially enhances proliferation of functionally competent CD4+CD25+FoxP3+ regulatory T cells |
Q34302055 | GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T lymphocyte subpopulations |
Q36072196 | GITR: a multifaceted regulator of immunity belonging to the tumor necrosis factor receptor superfamily |
Q37104636 | GM-CSF-induced CD11c+CD8a--dendritic cells facilitate Foxp3+ and IL-10+ regulatory T cell expansion resulting in suppression of autoimmune thyroiditis |
Q34510143 | GM-CSF-induced, bone-marrow-derived dendritic cells can expand natural Tregs and induce adaptive Tregs by different mechanisms |
Q38202991 | Genetic and epigenetic basis of Treg cell development and function: from a FoxP3-centered view to an epigenome-defined view of natural Treg cells |
Q34171280 | Genetic susceptibility to autoimmune thyroid disease: past, present, and future |
Q36444055 | Glucosamine Modulates T Cell Differentiation through Down-regulating N-Linked Glycosylation of CD25. |
Q36586957 | Guarding the immune system: suppression of autoimmunity by CD4+CD25+ immunoregulatory T cells |
Q24802813 | HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells |
Q34540245 | HSP70 enhances immunosuppressive function of CD4(+)CD25(+)FoxP3(+) T regulatory cells and cytotoxicity in CD4(+)CD25(-) T cells |
Q34852739 | Helicobacter pylori-specific CD4+ CD25high regulatory T cells suppress memory T-cell responses to H. pylori in infected individuals |
Q43073496 | Helios induces epigenetic silencing of IL2 gene expression in regulatory T cells |
Q40156868 | Hepatocellular carcinoma cell supernatants increase expansion and function of CD4(+)CD25(+) regulatory T cells |
Q35767591 | Higher Sensitivity of Foxp3+ Treg Compared to Foxp3- Conventional T Cells to TCR-Independent Signals for CD69 Induction |
Q77342616 | Homeostasis and anergy of CD4(+)CD25(+) suppressor T cells in vivo |
Q26853599 | Homeostasis and function of regulatory T cells (Tregs) in vivo: lessons from TCR-transgenic Tregs |
Q34604828 | Homeostasis of intestinal immune regulation |
Q36402763 | Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization |
Q37223366 | Homing in on acute graft vs. host disease: tissue-specific T regulatory and Th17 cells |
Q37596517 | How do regulatory T cells work? |
Q54568607 | How many mechanisms do regulatory T cells need? |
Q29614262 | How regulatory T cells work |
Q36758537 | Hsp65-producing Lactococcus lactis prevents experimental autoimmune encephalomyelitis in mice by inducing CD4+LAP+ regulatory T cells |
Q34529123 | Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells. |
Q41907086 | Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected]. |
Q33942128 | Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitro |
Q34626852 | Human FoxP3(+)CD4(+) regulatory T cells: their knowns and unknowns |
Q24656069 | Human T regulatory cell therapy: take a billion or so and call me in the morning |
Q42223144 | Human antigen-specific CD4⁺ CD25⁺ CD134⁺ CD39⁺ T cells are enriched for regulatory T cells and comprise a substantial proportion of recall responses |
Q40801370 | Human cd25(+)cd4(+) t regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function. |
Q47677023 | Human dendritic cells infected with an adenoviral vector suppress proliferation of autologous and allogeneic T cells |
Q37452486 | Human regulatory T cells are targets for human immunodeficiency Virus (HIV) infection, and their susceptibility differs depending on the HIV type 1 strain |
Q40852264 | Human regulatory T cells control TCR signaling and susceptibility to suppression in CD4+ T cells. |
Q34636235 | Human regulatory T cells rapidly suppress T cell receptor-induced Ca(2+), NF-κB, and NFAT signaling in conventional T cells. |
Q37387234 | Hydrodynamic vaccination with DNA encoding an immunologically privileged retinal antigen protects from autoimmunity through induction of regulatory T cells |
Q35571367 | IFN-α and CD46 stimulation are associated with active lupus and skew natural T regulatory cell differentiation to type 1 regulatory T (Tr1) cells |
Q82243350 | IL-10-producing Langerhans cells and regulatory T cells are responsible for depressed contact hypersensitivity in grafted skin |
Q37008475 | IL-13 production by regulatory T cells protects against experimental autoimmune encephalomyelitis independently of autoantigen |
Q35615786 | IL-15 and dermal fibroblasts induce proliferation of natural regulatory T cells isolated from human skin |
Q34428659 | IL-15 augments TCR-induced CD4+ T cell expansion in vitro by inhibiting the suppressive function of CD25 High CD4+ T cells. |
Q33851806 | IL-21 receptor signalling partially mediates Th2-mediated allergic airway responses |
Q36108954 | IL-33 Receptor-Expressing Regulatory T Cells Are Highly Activated, Th2 Biased and Suppress CD4 T Cell Proliferation through IL-10 and TGFβ Release |
Q36070380 | INFα-2b inhibitory effects on CD4(+)CD25(+)FOXP3(+) regulatory T cells in the tumor microenvironment of C57BL/6 J mice with melanoma xenografts. |
Q41988688 | Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood |
Q61651904 | Identification of a CD4+CD25+ T?cell subset committedin vivoto suppress antigen-specific T?cell responses without additional stimulation |
Q33988297 | Identification of novel immunoregulatory molecules in human thymic regulatory CD4+CD25+ T cells by phage display |
Q42798944 | Idiotype‐specific CD4+CD25+ T suppressor cells prevent, by limiting antibody diversity, the occurrence of anti‐dextran antibodies crossreacting with histone H3 |
Q36395703 | Imbalance of regulatory T cells in human autoimmune diseases |
Q36354925 | Imbalanced signal transduction in regulatory T cells expressing the transcription factor FoxP3. |
Q42181842 | Immature dendritic cells convert anergic nonregulatory T cells into Foxp3- IL-10+ regulatory T cells by engaging CD28 and CTLA-4. |
Q94470282 | Immune Suppression in Pregnancy and Cancer: Parallels and Insights |
Q38020961 | Immune checkpoints in central nervous system autoimmunity. |
Q35216470 | Immune regulation by CD4+CD25+ regulatory T cells: implications for transplantation tolerance |
Q35766216 | Immune regulation through mitochondrion-dependent dendritic cell death induced by T regulatory cells |
Q37606564 | Immune regulatory cells in umbilical cord blood: T regulatory cells and mesenchymal stromal cells |
Q47325622 | Immunoglobulin and lymphocyte responses following silica exposure in New Zealand mixed mice |
Q34374572 | Immunologic self tolerance maintained by T-cell-mediated control of self-reactive T cells: implications for autoimmunity and tumor immunity |
Q34509694 | Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. |
Q34839054 | Immunological considerations in in utero hematopoetic stem cell transplantation (IUHCT) |
Q34609440 | Immunological principles of T-cell-mediated adverse drug reactions in skin |
Q90050590 | Immunometabolic Checkpoints of Treg Dynamics: Adaptation to Microenvironmental Opportunities and Challenges |
Q42590646 | Immunomodulatory effects of mesenchymal stromal cells in Crohn's disease |
Q35683325 | Immunoregulatory T cells in autoimmunity |
Q35040824 | Immunoregulatory T cells in cancer immunotherapy. |
Q26798402 | Immunosuppressive Mechanisms of Malignant Gliomas: Parallels at Non-CNS Sites |
Q54125905 | Impact of alemtuzumab treatment on the survival and function of human regulatory T cells in vitro. |
Q36886212 | Impact of methimazole treatment on magnesium concentration and lymphocytes activation in adolescents with Graves' disease. |
Q53232463 | Impaired immune regulation after radioiodine therapy for Graves' disease and the protective effect of Methimazole. |
Q80516143 | Importance of CD80/CD86-CD28 interactions in the recognition of target cells by CD8+CD122+ regulatory T cells |
Q42951816 | Improved generation of anti-tumor immunity by antigen dose limitation |
Q34593804 | In vitro Treg suppression assays |
Q41774667 | In vitro induction of regulatory T cells by anti-CD3 antibody in humans |
Q84978571 | In vitro lipopolysaccharide treatment alters regulatory T cell properties in chickens |
Q51987584 | In vivo depletion of CD4+CD25+ regulatory T cells enhances the antigen-specific primary and memory CTL response elicited by mature mRNA-electroporated dendritic cells. |
Q35171080 | In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro |
Q40511233 | In vivo elimination of CD25+ regulatory T cells leads to tumor rejection of B16F10 melanoma, when combined with interleukin-12 gene transfer |
Q39559727 | In vivo inhibition of human CD19-targeted effector T cells by natural T regulatory cells in a xenotransplant murine model of B cell malignancy |
Q42726353 | Increase of CD4(+)CD25(+) T cells in Smad3(-/-) mice |
Q48021387 | Increased Susceptibility to Plasmodium falciparum in Infants is associated with Low, not High, Placental Malaria Parasitemia |
Q44466939 | Increased production of interleukin-17 over interleukin-10 by treg cells implicates inducible costimulator molecule in experimental spondyloarthritis |
Q33770196 | Induced Regulatory T Cells Superimpose Their Suppressive Capacity with Effector T Cells in Lymph Nodes via Antigen-Specific S1p1-Dependent Egress Blockage |
Q33814943 | Inducing CTLA-4-dependent immune regulation by selective CD28 blockade promotes regulatory T cells in organ transplantation |
Q42804882 | Induction of Donor-Specific Tolerance Using Superagonistic CD28 Antibody in Rat Renal Allografts: Regulatory T-Cell Expansion Before Engraftment May Be Important |
Q36957222 | Induction of Th17 cells in the tumor microenvironment improves survival in a murine model of pancreatic cancer |
Q47240621 | Induction of antigen-specific immunologic tolerance by in vivo and in vitro antigen-specific expansion of naturally arising Foxp3+CD25+CD4+ regulatory T cells |
Q30907499 | Induction of granzyme B expression in T-cell receptor/CD28-stimulated human regulatory T cells is suppressed by inhibitors of the PI3K-mTOR pathway |
Q34983446 | Induction of immune tolerance by dendritic cells: implications for preventative and therapeutic immunotherapy of autoimmune disease |
Q37120570 | Induction of mucosal tolerance in SLE: a sniff or a sip away from ameliorating lupus? |
Q37096361 | Inflammation in lung carcinogenesis: new targets for lung cancer chemoprevention and treatment |
Q39188242 | Influence of CD4+CD25+ T cells on Plasmodium berghei NK65 infection in BALB/c mice |
Q43282513 | Influence of enamel matrix derivative on primary CD4+ T-helper lymphocyte migration, CD25 activation, and apoptosis. |
Q42112406 | Influence of serum and soluble CD25 (sCD25) on regulatory and effector T-cell function in hepatocellular carcinoma |
Q34656577 | Inhibiting cardiac allograft rejection with interleukin-35 therapy combined with decitabine treatment in mice |
Q28221643 | Inhibition of NF-kappa B during human dendritic cell differentiation generates anergy and regulatory T-cell activity for one but not two human leukocyte antigen DR mismatches |
Q40311949 | Inhibition of T-cell responses by CD4 on an antigen-presenting cell |
Q37455696 | Innate immunity and asthma |
Q35662882 | Integrin αvβ8-Mediated TGF-β Activation by Effector Regulatory T Cells Is Essential for Suppression of T-Cell-Mediated Inflammation. |
Q55337327 | Interactions Between the Neuroendocrine System and T Lymphocytes in Diabetes. |
Q80984051 | Interactions between immune cells and their microenvironment |
Q34527240 | Interleukin 2 signaling is required for CD4(+) regulatory T cell function |
Q36796532 | Interleukin-10 deficiency impairs regulatory T cell-derived neuropilin-1 functions and promotes Th1 and Th17 immunity |
Q47291768 | Interleukin-2 blocks the antitumour activity caused by depletion of CD25 cells in a murine renal adenocarcinoma model |
Q45387848 | Interleukin-6 small interfering RNA improved the herpes simplex virus-induced systemic inflammation in vivo Behcet's disease-like mouse model |
Q35849633 | Intratumoral CD4+CD25+ regulatory T-cell-mediated suppression of infiltrating CD4+ T cells in B-cell non-Hodgkin lymphoma |
Q37864700 | Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 family |
Q33888375 | Janus kinase 3 (Jak3) is essential for common cytokine receptor gamma chain (gamma(c))-dependent signaling: comparative analysis of gamma(c), Jak3, and gamma(c) and Jak3 double-deficient mice |
Q92358696 | Knockdown of serine/threonine-protein kinase 24 promotes tumorigenesis and myeloid-derived suppressor cell expansion in an orthotopic immunocompetent gastric cancer animal model |
Q36227859 | LAT-mediated signaling in CD4+CD25+ regulatory T cell development |
Q83921292 | Lack of IL-2 in PPAR-α-deficient mice triggers allergic contact dermatitis by affecting regulatory T cells |
Q80097552 | Large-scale expansion of rat CD4+ CD25+ T(reg) cells in the absence of T-cell receptor stimulation |
Q37408819 | Latency-associated peptide identifies a novel CD4+CD25+ regulatory T cell subset with TGFbeta-mediated function and enhanced suppression of experimental autoimmune encephalomyelitis |
Q36073220 | Layers of dendritic cell-mediated T cell tolerance, their regulation and the prevention of autoimmunity |
Q35101466 | Levels of interleukin-35 and its relationship with regulatory T-cells in chronic hepatitis B patients |
Q39127345 | Loss of Tolerance and Autoimmunity Affecting Multiple Organs inSTAT5A/5B-Deficient Mice |
Q53319780 | Lymphopenia in occupational pulmonary silicosis with or without autoimmune disease. |
Q36278295 | MHC class II derived recombinant T cell receptor ligands protect DBA/1LacJ mice from collagen-induced arthritis |
Q36369536 | Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells |
Q35624707 | Mechanisms of peripheral immune tolerance: conversion of the immune to the unresponsive phenotype |
Q37111968 | Mechanisms of regulatory T-cell suppression - a diverse arsenal for a moving target |
Q38059338 | Mesenchymal stromal cells and regulatory T cells: the Yin and Yang of peripheral tolerance? |
Q42210265 | Migration matters: regulatory T-cell compartmentalization determines suppressive activity in vivo |
Q38097311 | Modulating T regulatory cells in cancer: how close are we? |
Q41895496 | Modulation of monocyte/macrophage function by human CD4+CD25+ regulatory T cells |
Q44632333 | Modulation of tryptophan catabolism by regulatory T cells. |
Q50671091 | Molecular Mechanisms of Regulatory T Cell Development and Suppressive Function |
Q38008361 | Molecular mechanisms of treg-mediated T cell suppression |
Q42138753 | Monoclonal regulatory T cells provide insights into T cell suppression |
Q35792672 | Multi-peptide coupled-cell tolerance ameliorates ongoing relapsing EAE associated with multiple pathogenic autoreactivities |
Q38023409 | Multiple treg suppressive modules and their adaptability. |
Q81862487 | Murine liver antigen presenting cells control suppressor activity of CD4+CD25+ regulatory T cells |
Q53990042 | Murine metal-induced systemic autoimmunity: baseline and stimulated cytokine mRNA expression in genetically susceptible and resistant strains. |
Q35740112 | Murine regulatory T cells contain hyperproliferative and death-prone subsets with differential ICOS expression |
Q53523527 | Natural Tregs, CD4+CD25+ inhibitory hybridomas, and their cell contact dependent suppression. |
Q34374592 | Natural regulatory CD4 T cells expressing CD25. |
Q34676250 | Natural regulatory T cells in autoimmunity |
Q29619194 | Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self |
Q35146722 | Negative T cell costimulation and islet tolerance. |
Q36278051 | Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells |
Q90197782 | Next-generation regulatory T cell therapy |
Q34299829 | Non-Th2 regulatory T-cell control of Th1 autoimmunity |
Q33638166 | Normal human pregnancy results in maternal immune activation in the periphery and at the uteroplacental interface |
Q34506140 | Normal regulatory alpha/beta T cells effectively eliminate abnormally activated T cells lacking the interleukin 2 receptor beta in vivo |
Q36938411 | Novel exosome-targeted CD4+ T cell vaccine counteracting CD4+25+ regulatory T cell-mediated immune suppression and stimulating efficient central memory CD8+ CTL responses |
Q36399562 | Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells. |
Q36537926 | OX40 triggering blocks suppression by regulatory T cells and facilitates tumor rejection |
Q37761492 | OX40-OX40 ligand interaction in T-cell-mediated immunity and immunopathology. |
Q41927855 | Obstructive jaundice expands intrahepatic regulatory T cells, which impair liver T lymphocyte function but modulate liver cholestasis and fibrosis. |
Q38161566 | Optimizing the use of regulatory T cells in allotransplantation: recent advances and future perspectives |
Q36097025 | Oral Squamous Carcinoma Cells Express B7-H1 and B7-DC Receptors in Vivo |
Q34305347 | Osteoclast activated FoxP3+ CD8+ T-cells suppress bone resorption in vitro. |
Q64265316 | PD-1 regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer |
Q42017650 | PD-L1 negatively regulates CD4+CD25+Foxp3+ Tregs by limiting STAT-5 phosphorylation in patients chronically infected with HCV. |
Q34997285 | PTEN inhibits IL-2 receptor-mediated expansion of CD4+ CD25+ Tregs |
Q77704341 | Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signals |
Q87245704 | Participation of T regulatory cells in equine recurrent airway obstruction |
Q41446869 | Pathogenic T cells have a paradoxical protective effect in murine autoimmune diabetes by boosting Tregs. |
Q36652177 | Physiological roles of murine DAP10 adapter protein in tumor immunity and autoimmunity |
Q34774087 | Plasticity and overlap of in vitro-induced regulatory T-cell markers in healthy humans |
Q73688321 | Policing the regulators |
Q33927418 | Pregnancy induces a fetal antigen-specific maternal T regulatory cell response that contributes to tolerance |
Q37669512 | Preoperative lymphocyte-to-monocyte ratio predicts survival in primary hepatitis B virus-positive hepatocellular carcinoma after curative resection |
Q48751155 | Prevention of lupus nephritis development in NZB/NZW mice by selective blockade of CD28. |
Q38806901 | Prognostic value of preoperative lymphocyte-to-monocyte ratio in pancreatic adenocarcinoma |
Q40217993 | Prognostic value of preoperative peripheral blood monocyte count in patients with colorectal liver metastasis after liver resection |
Q43856158 | Progranulin promotes tumour necrosis factor-induced proliferation of suppressive mouse CD4⁺ Foxp3⁺ regulatory T cells. |
Q91638895 | Protease Activated Receptor 4 as a Novel Modulator of Regulatory T Cell Function |
Q46401511 | Putative regulatory T cells are impaired in cord blood from neonates with hereditary allergy risk |
Q42392644 | Raf signaling but not the ERK effector SAP-1 is required for regulatory T cell development |
Q30437887 | Rapid and selective expansion of nonclonotypic T cells in regulatory T cell-deficient, foreign antigen-specific TCR-transgenic scurfy mice: antigen-dependent expansion and TCR analysis |
Q83194142 | Re-establishing immunological self-tolerance in autoimmune disease |
Q30573918 | Real-time immune cell interactions in target tissue during autoimmune-induced damage and graft tolerance |
Q45148312 | Recent thymic origin, differentiation, and turnover of regulatory T cells |
Q33629928 | Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia |
Q41146735 | Recovered changes in the spleen by agmatine treatment after transient cerebral ischemia |
Q28595009 | Recruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor |
Q37583435 | Reduction of retrovirus-induced immunosuppression by in vivo modulation of T cells during acute infection |
Q36631649 | Regulating regulatory T cells |
Q37474900 | Regulating the regulators: costimulatory signals control the homeostasis and function of regulatory T cells |
Q26823216 | Regulation generation: the suppressive functions of human regulatory T cells |
Q36097043 | Regulation of CD4+CD25+ regulatory T cell activity: it takes (IL-)two to tango |
Q37400302 | Regulation of interferon gamma signaling by suppressors of cytokine signaling and regulatory T cells |
Q33860019 | Regulation of the T helper cell type 2 (Th2)/T regulatory cell (Treg) balance by IL-4 and STAT6 |
Q34842135 | Regulation of tumour immunity by CD25+ T cells |
Q37051205 | Regulatory CD8+ T cells associated with erosion of immune surveillance in persistent virus infection suppress in vitro and have a reversible proliferative defect |
Q64949232 | Regulatory Role of CD4+ T Cells in Myocarditis. |
Q92129582 | Regulatory T (Treg) cells in cancer: Can Treg cells be a new therapeutic target? |
Q52715799 | Regulatory T Cells As Potential Targets for HIV Cure Research. |
Q90220063 | Regulatory T Cells in Tumor Microenvironment and Approach for Anticancer Immunotherapy |
Q48668293 | Regulatory T Cells: Molecular and Cellular Basis for Immunoregulation |
Q37233985 | Regulatory T cell suppression is potentiated by target T cells in a cell contact, IL-35- and IL-10-dependent manner |
Q21131435 | Regulatory T cell suppressive potency dictates the balance between bacterial proliferation and clearance during persistent Salmonella infection |
Q36388773 | Regulatory T cell-mediated transplantation tolerance |
Q36986732 | Regulatory T cells - a brief history and perspective |
Q35582278 | Regulatory T cells accumulate in the lung allergic inflammation and efficiently suppress T-cell proliferation but not Th2 cytokine production |
Q37900645 | Regulatory T cells and IL-17-producing cells in graft-versus-host disease |
Q36079905 | Regulatory T cells and autoimmune disease |
Q36079900 | Regulatory T cells and intestinal homeostasis |
Q41834768 | Regulatory T cells and the control of the allergic response. |
Q37338455 | Regulatory T cells and their role in rheumatic diseases: a potential target for novel therapeutic development |
Q36969926 | Regulatory T cells and toll-like receptors: regulating the regulators |
Q35029947 | Regulatory T cells control HIV replication in activated T cells through a cAMP-dependent mechanism |
Q28267935 | Regulatory T cells exert checks and balances on self tolerance and autoimmunity |
Q82609485 | Regulatory T cells exhibit enhanced migratory characteristics, a feature impaired in patients with multiple sclerosis |
Q54332931 | Regulatory T cells expanded by rapamycin in vitro suppress colitis in an experimental mouse model. |
Q35621984 | Regulatory T cells for tolerance therapy: revisiting the concept |
Q35553553 | Regulatory T cells in acute myelogenous leukemia: is it time for immunomodulation? |
Q84073243 | Regulatory T cells in cancer |
Q91297827 | Regulatory T cells in cancer immunosuppression - implications for anticancer therapy |
Q39044365 | Regulatory T cells in cancer immunotherapy |
Q36534833 | Regulatory T cells in graft-versus-host disease. |
Q36562855 | Regulatory T cells in human autoimmune diseases |
Q82076756 | Regulatory T cells in rheumatoid arthritis |
Q36203572 | Regulatory T cells in the control of autoimmune diabetes: the case of the NOD mouse |
Q34348983 | Regulatory T cells in the control of immune pathology. |
Q36563523 | Regulatory T cells in the periphery |
Q35092535 | Regulatory T cells in transplantation tolerance |
Q34786943 | Regulatory T cells in transplantation. |
Q37691776 | Regulatory T cells in transplantation: does extracellular adenosine triphosphate metabolism through CD39 play a crucial role? |
Q34633260 | Regulatory T cells inhibit acute IFN-γ synthesis without blocking T-helper cell type 1 (Th1) differentiation via a compartmentalized requirement for IL-10 |
Q41891844 | Regulatory T cells modulate Th2 responses induced by Brugia pahangi third-stage larvae |
Q37412624 | Regulatory T cells overturned: the effectors fight back |
Q90518726 | Regulatory T cells promote corneal endothelial cell survival following transplantation via interleukin-10 |
Q35472407 | Regulatory T cells require TCR signaling for their suppressive function |
Q34531452 | Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide |
Q35092531 | Regulatory T cells under scrutiny |
Q26827787 | Regulatory T cells: Mechanisms of suppression and impairment in autoimmune liver disease |
Q37967097 | Regulatory T cells: banned cells for decades |
Q37593768 | Regulatory T cells: how do they suppress immune responses? |
Q35912319 | Regulatory T cells: peace keepers in the gut. |
Q37697589 | Regulatory T cells: roles of T cell receptor for their development and function |
Q37498880 | Regulatory T lymphocytes from ALS mice suppress microglia and effector T lymphocytes through different cytokine-mediated mechanisms |
Q36563537 | Regulatory T-cell physiology and application to treat autoimmunity |
Q36212618 | Regulatory T-cells in chronic lymphocytic leukemia and autoimmune diseases |
Q37914338 | Regulatory T-cells in systemic lupus erythematosus and rheumatoid arthritis |
Q46934849 | Regulatory-T-cell inhibition versus depletion: the right choice in cancer immunotherapy |
Q37205678 | Regulatory T cell subsets in filarial infection and their function |
Q48020021 | Resistance of regulatory T cells to glucocorticoid-induced [corrected] TNFR family-related protein (GITR) during Plasmodium yoelii infection. |
Q33373073 | Resting regulatory CD4 T cells: a site of HIV persistence in patients on long-term effective antiretroviral therapy |
Q36224502 | Resveratrol analogue HS-1793 induces the modulation of tumor-derived T cells |
Q41132577 | Reversal of gastrointestinal carcinoma-induced immunosuppression and induction of antitumoural immunity by a combination of cyclophosphamide and gene transfer of IL-12. |
Q35705245 | Revival of the regulatory T cell: new targets for drug development |
Q35981635 | Role of CD25+ dendritic cells in the generation of Th17 autoreactive T cells in autoimmune experimental uveitis |
Q36563507 | Role of TCR specificity in CD4+ CD25+ regulatory T-cell selection |
Q37090518 | Role of regulatory T cells in gastrointestinal inflammatory disease |
Q38830072 | Roles of regulatory T cells in cancer immunity |
Q35671669 | Routes to transplant tolerance versus rejection; the role of cytokines. |
Q40771683 | SHARPIN controls the development of regulatory T cells |
Q37701348 | Self-tolerance and autoimmunity in a regulatory T cell model |
Q44418597 | Sequential Involvement of Two Distinct CD4+ Regulatory T Cells during the Course of Transplantable Tumor Growth and Protection from 3–Methylcholanthrene‐induced Tumorigenesis by CD25–depletion |
Q61806576 | Sex Differences in Mouse Popliteal Lymph Nodes |
Q37055402 | Shifting the equilibrium in cancer immunoediting: from tumor tolerance to eradication |
Q44788673 | Simultaneous blockade of co-stimulatory signals, CD28 and ICOS, induced a stable tolerance in rat heart transplantation |
Q37702272 | Soluble common gamma chain exacerbates COPD progress through the regulation of inflammatory T cell response in mice |
Q27002575 | Sorting through subsets: which T-cell populations mediate highly effective adoptive immunotherapy? |
Q34032006 | Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice. |
Q34190602 | Specificity, restriction and effector mechanisms of immunoregulatory CD8 T cells |
Q39402895 | Spectrum of T-lymphocyte activities regulating allergic lung inflammation |
Q40360050 | Standardization, Evaluation, and Area-Under-Curve Analysis of Human and Murine Treg Suppressive Function |
Q34111451 | Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance |
Q42906446 | Stimulation of α7 Nicotinic Acetylcholine Receptor by Nicotine Increases Suppressive Capacity of Naturally Occurring CD4+CD25+Regulatory T Cells in Mice In Vitro |
Q36203554 | Stress proteins as inducers and targets of regulatory T cells in arthritis |
Q80405125 | Studies on naïve CD4+CD25+T cells inhibition of naïve CD4+CD25- T cells in mixed lymphocyte cultures |
Q37224027 | Subpopulations of bovine WC1(+) gammadelta T cells rather than CD4(+)CD25(high) Foxp3(+) T cells act as immune regulatory cells ex vivo |
Q44628780 | Subpopulations of equine blood lymphocytes expressing regulatory T cell markers. |
Q56903922 | Superantigen-Induced Regulatory T Cells Display Different Suppressive Functions in the Presence or Absence of Natural CD4+CD25+ Regulatory T Cells In Vivo |
Q35762936 | Supplementation of CD4+CD25+ regulatory T cells suppresses experimental autoimmune uveoretinitis |
Q37967572 | Suppression assays with human T regulatory cells: a technical guide. |
Q33359540 | Suppression of HIV-specific and allogeneic T cell activation by human regulatory T cells is dependent on the strength of signals |
Q30388030 | Suppression of Th2 and Tfh immune reactions by Nr4a receptors in mature T reg cells |
Q45106594 | Suppressive properties of human CD4+CD25+ regulatory T cells are dependent on CTLA-4 expression |
Q37290190 | Suppressor T cells regulate the nonanergic cell population that remains after peripheral tolerance is induced to the Mls-1 antigen in T cell receptor Vbeta 8.1 transgenic mice |
Q35849305 | Suppressor activity and potency among regulatory T cells is discriminated by functionally active CD44 |
Q36376333 | Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses |
Q37000546 | Systemic targeting of CpG-ODN to the tumor microenvironment with anti-neu-CpG hybrid molecule and T regulatory cell depletion induces memory responses in BALB-neuT tolerant mice |
Q30252330 | T Cells Deficient in the Tyrosine Phosphatase SHP-1 Resist Suppression by Regulatory T Cells |
Q36370619 | T cell regulation as a side effect of homeostasis and competition |
Q73703389 | T cells at the turn of the twenty-first century |
Q92715292 | T cells engrafted with a UniCAR 28/z outperform UniCAR BB/z-transduced T cells in the face of regulatory T cell-mediated immunosuppression |
Q39017604 | T regulatory cell mediated immunotherapy for solid organ transplantation: A clinical perspective |
Q36425917 | T regulatory cells as an immunotherapy for transplantation |
Q35459820 | T regulatory cells: aid or hindrance in the clearance of disease? |
Q37993692 | T-cell receptor signaling and the pathogenesis of autoimmune arthritis: insights from mouse and man. |
Q34552317 | T-cell tolerance and autoimmune diabetes |
Q36079878 | T-cell tolerance and autoimmunity to systemic and tissue-restricted self-antigens |
Q24805370 | T-cell-mediated control of autoimmunity |
Q35589560 | T-helper cell tolerance to ubiquitous nuclear antigens |
Q50567211 | T-lymphocyte and glycemic status after vitamin D treatment in type 1 diabetes: A randomized controlled trial with sequential crossover. |
Q34987498 | T-regulatory cells: are we re-discovering T suppressors? |
Q37358159 | TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes |
Q47667692 | TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes |
Q38647664 | TGF-beta-dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasis |
Q34556464 | TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells |
Q38632049 | TGF-β blockade depletes T regulatory cells from metastatic pancreatic tumors in a vaccine dependent manner |
Q53644347 | TRAF1 regulates Th2 differentiation, allergic inflammation and nuclear localization of the Th2 transcription factor, NIP45. |
Q38224804 | TREG-cell therapies for autoimmune rheumatic diseases. |
Q89861814 | Technical Considerations in Ex Vivo Human Regulatory T Cell Migration and Suppression Assays |
Q27312315 | Temporal pattern of ICAM-I mediated regulatory T cell recruitment to sites of inflammation in adoptive transfer model of multiple sclerosis |
Q21245397 | Th17/Treg ratio derived using DNA methylation analysis is associated with the late phase asthmatic response |
Q47755372 | The Dual Role of Treg in Cancer |
Q64241294 | The Effects of Immunosuppressive Factors on Primary Dendritic Cells from C57BL/6 and CBA Mice |
Q37088900 | The Foxp3+ regulatory T cell: a jack of all trades, master of regulation |
Q24633549 | The PD-1 pathway in tolerance and autoimmunity |
Q36063908 | The Preoperative Peripheral Blood Monocyte Count Is Associated with Liver Metastasis and Overall Survival in Colorectal Cancer Patients |
Q36222003 | The Role of Regulatory B Cell-Like Malignant Cells and Treg Cells in the Mouse Model of BCL1 Tumor Dormancy |
Q37364109 | The T-cell receptor repertoire of regulatory T cells |
Q64256609 | The Tolerogenic Function of Regulatory T Cells in Pregnancy and Cancer |
Q64235834 | The absolute counts of peripheral T lymphocyte subsets in patient with ankylosing spondylitis and the effect of low-dose interleukin-2 |
Q47955968 | The altered PD-1/PD-L1 pathway delivers the 'one-two punch' effects to promote the Treg/Th17 imbalance in pre-eclampsia |
Q33953206 | The causative H+/K+ ATPase antigen in the pathogenesis of autoimmune gastritis. |
Q38008355 | The cellular and molecular mechanisms of immuno-suppression by human type 1 regulatory T cells |
Q83194650 | The cellular basis of cardiac allograft rejection. IX. Ratio of naïve CD4+CD25+ T cells/CD4+CD25- T cells determines rejection or tolerance |
Q37274250 | The development and function of regulatory T cells |
Q43061565 | The different effects of cyclosporin A and rapamycin on regulatory CD4+CD25+ T cells: potential relationship with transplant tolerance induction |
Q46046855 | The effect of various disease-modifying anti-rheumatic drugs on the suppressive function of CD4⁺CD25⁺ regulatory T cells |
Q37176386 | The effects of immunosuppression on regulatory CD4(+)CD25(+) T cells: impact on immunosuppression selection in transplantation |
Q37727704 | The fate of regulatory T cells: survival or apoptosis |
Q42656251 | The immune system in cancer metastasis: friend or foe? |
Q57041494 | The immunoregulatory role of CD4+FoxP3+CD25−regulatory T cells in lungs of mice infected withBordetella pertussis |
Q38350483 | The impact of biological therapy on regulatory T cells in rheumatoid arthritis |
Q36882243 | The influence of IL-2 family cytokines on activation and function of naturally occurring regulatory T cells |
Q35916845 | The influence of commensal bacteria on infection with enteric viruses |
Q28258462 | The inhibitory cytokine IL-35 contributes to regulatory T-cell function |
Q42441813 | The inhibitory function of B7 costimulators in T cell responses to foreign and self-antigens |
Q42758392 | The interplay between regulatory T cells and metabolism in immune regulation |
Q35928046 | The molecular mechanisms of regulatory T cell immunosuppression |
Q83834480 | The myocardium of fetuses with endocardial fibroelastosis contains fewer B and T lymphocytes than normal control myocardium |
Q34238425 | The origin and regulation of autopathogenic T cells |
Q54518671 | The paradox role of regulatory T cells in ischemic stroke. |
Q28236898 | The pathogenesis of immune thrombocytopaenic purpura |
Q35154721 | The peripheral generation of CD4+ CD25+ regulatory T cells |
Q50987847 | The plasticity and stability of regulatory T cells. |
Q34009654 | The power and the promise of restimulation-induced cell death in human immune diseases |
Q34604823 | The puzzling world of murine T regulatory cells. |
Q46774844 | The relationship of FOXP3 expression and clinicopathological characteristics in adult T-cell leukemia/lymphoma |
Q35207494 | The role of CD4(+)CD25(+) regulatory T cells in Leishmania infection |
Q54587598 | The role of CD4CD25 T cells in autoantibody production in murine lupus. |
Q36141498 | The role of CD8+CD28 regulatory cells in suppressing myasthenia gravis-associated responses by a dual altered peptide ligand |
Q36747499 | The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease |
Q30441254 | The role of physiological self-antigen in the acquisition and maintenance of regulatory T-cell function |
Q35107549 | The role of regulatory T cells in controlling immunologic self-tolerance |
Q38035240 | The role of regulatory T cells in neurodegenerative diseases |
Q37738676 | The role of regulatory T cells in respiratory infections and allergy and asthma. |
Q36652214 | The role of regulatory T cells in the control of natural killer cells: relevance during tumor progression |
Q27004368 | The role of regulatory T cells in the pathogenesis of sepsis and its clinical implication |
Q49710338 | The role of salt for immune cell function and disease. |
Q36822300 | The role of the LAT-PLC-gamma1 interaction in T regulatory cell function |
Q34569892 | The role of the transcription factor Foxp3 in the development of regulatory T cells |
Q36535760 | The role of virus-induced regulatory T cells in immunopathology |
Q37803117 | The roles of c‐rel and interleukin‐2 in tolerance: a molecular explanation of self–nonself discrimination |
Q34648178 | The soluble isoform of CTLA-4 as a regulator of T-cell responses |
Q36715471 | The straw that stirs the drink: insight into the pathogenesis of inflammatory bowel disease revealed through the study of microflora-induced inflammation in genetically modified mice |
Q39455086 | The suppressive effect of CD25+Treg cells on Th1 differentiation requires cell-cell contact partially via TGF-β production |
Q33826591 | The third function of the thymus. |
Q28080019 | The thymus and rheumatology: should we care? |
Q92312875 | Theoretical modeling reveals that regulatory T cells increase T-cell interaction with antigen-presenting cells for stable immune tolerance |
Q28066677 | Therapeutic efficacy of monthly subcutaneous injection of daclizumab in relapsing multiple sclerosis |
Q82771162 | Therapeutic potential of self-antigen-specific CD4+ CD25+ regulatory T cells selected in vitro from a polyclonal repertoire |
Q35867877 | Therapeutic vaccination using CD4+CD25+ antigen-specific regulatory T cells |
Q36719265 | Thymic deletion and regulatory T cells prevent antimyeloperoxidase GN. |
Q73688337 | Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide |
Q36959215 | Thymic versus induced regulatory T cells - who regulates the regulators? |
Q27013062 | Thymus, innate immunity and autoimmune arthritis: interplay of gene and environment |
Q74121842 | Tolerance and bystander suppression, with involvement of CD25-positive cells, is induced in rats receiving serum from ovalbumin-fed donors |
Q61679981 | Tolerance and immunity in a mathematical model of T-cell mediated suppression |
Q47948107 | Tolerance associated with cord blood transplantation may depend on the state of host dendritic cells |
Q42157420 | Tolerance of activated pathogenic CD4+ T cells by transcriptional targeting of dendritic cells |
Q36943091 | Tolerance to melanin-associated antigen in autoimmune uveitis is mediated by CD4+CD25+ T-regulatory cells |
Q35877199 | Tolerance, not immunity, crucially depends on IL-2. |
Q34264024 | Toll-like receptor 2 controls expansion and function of regulatory T cells |
Q45252623 | Total colectomy improves altered distribution of regulatory T cells in patients with ulcerative colitis |
Q34572232 | Transforming growth factor-beta in T-cell biology |
Q24804340 | Transforming growth factor-beta-induced regulatory T cells referee inflammatory and autoimmune diseases |
Q36736462 | Translational mini-review series on vaccines: Dendritic cell-based vaccines in renal cancer |
Q42091259 | Transplantation survival is maintained by granzyme B+ regulatory cells and adaptive regulatory T cells |
Q46602988 | Treatment of Uveitis by In Situ Administration of Ex Vivo-Activated Polyclonal Regulatory T Cells. |
Q99726047 | Treg Enhancing Therapies to Treat Autoimmune Diseases |
Q104068523 | Treg cell therapy: how cell heterogeneity can make the difference |
Q36192911 | Treg cells, life history, and diversity |
Q34273253 | Treg lymphocytes in autoimmune uveitis. |
Q36497238 | Treg-mediated suppression of atherosclerosis requires MYD88 signaling in DCs. |
Q35951541 | Tregs and transplantation tolerance |
Q37788679 | Tumor Infiltrating Regulatory T Cells: Tractable Targets for Immunotherapy |
Q36403539 | Tumor cells convert immature myeloid dendritic cells into TGF-beta-secreting cells inducing CD4+CD25+ regulatory T cell proliferation |
Q37085357 | Tumor-induced impairment of TCR signaling results in compromised functionality of tumor-infiltrating regulatory T cells |
Q64108546 | Turning the Tide Against Regulatory T Cells |
Q41852651 | Type I diabetes-associated tolerogenic properties of interleukin-2. |
Q34193045 | UXT is a novel regulatory factor of regulatory T cells associated with Foxp3. |
Q53101377 | Unique roles of Schistosoma japonicum protein Sj16 to induce IFN-γ and IL-10 producing CD4(+)CD25(+) regulatory T cells in vitro and in vivo. |
Q37190443 | Unravelling the association of partial T-cell immunodeficiency and immune dysregulation |
Q44476443 | Upregulation of GRAIL is associated with remission of ulcerative colitis. |
Q37892594 | Vaccination therapy in renal cell carcinoma: current position and future options in metastatic and localized disease |
Q33768325 | Virus-induced dysfunction of CD4+CD25+ T cells in patients with HTLV-I-associated neuroimmunological disease |
Q35845351 | Vγ1+ γδ T cells reduce IL-10-producing CD4+CD25+ T cells in the lung of ovalbumin-sensitized and challenged mice |
Q42278097 | WITHDRAWN: The majority of T cells, including Treg cells, are developed from CD4(-)CD8(-)T progenitor cells without the involvement of the CD4(+)CD8(+) stage in the thymus |
Q33745150 | What is the role of regulatory T cells in transplantation tolerance? |
Q37227956 | What roles do regulatory T cells play in the control of the adaptive immune response? |
Q35155949 | What's the difference between CD80 and CD86? |
Q36762514 | When three is not a crowd: a Crossregulation model of the dynamics and repertoire selection of regulatory CD4+ T cells. |
Q52689973 | When worlds collide: Th17 and Treg cells in cancer and autoimmunity. |
Q37998914 | Working out mechanisms of controlled/physiologic inflammation in the GI tract |
Q82893705 | [Immunological aspects of atherosclerosis] |
Q61628000 | c-Rel but not NF-κB1 is important for T regulatory cell development |
Q37137541 | mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function |